MeSH term
Frequency | Condition_Probility | Humans | 89 | 0.0 |
Animals | 30 | 0.0 |
Research Support, Non-U.S. Gov't | 45 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 45 | 0.0 |
Cell Line, Transformed | 4 | 0.0 |
*DNA Damage | 6 | 1.0 |
DNA Repair | 12 | 1.0 |
Fibroblasts | 2 | 0.0 |
Models, Genetic | 8 | 0.0 |
Phosphorylation | 7 | 0.0 |
Comparative Study | 10 | 0.0 |
DNA Helicases/*genetics/physiology | 2 | 50.0 |
Gene Frequency | 2 | 0.0 |
Genotype | 4 | 0.0 |
*Loss of Heterozygosity | 2 | 0.0 |
Mutation | 19 | 0.0 |
Phenotype | 9 | 0.0 |
Plasmids/genetics | 2 | 0.0 |
DNA/*metabolism | 4 | 0.0 |
DNA Damage | 8 | 0.0 |
*DNA Repair | 5 | 0.0 |
Models, Biological | 5 | 0.0 |
Protein p53/genetics/metabolism | 2 | 2.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 7 | 0.0 |
Blotting, Western | 3 | 0.0 |
Cell Line, Tumor | 2 | 0.0 |
Heterozygote | 3 | 0.0 |
Cells, Cultured | 7 | 0.0 |
Female | 9 | 0.0 |
RNA, Messenger/metabolism | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 3 | 0.0 |
DNA/chemistry/metabolism | 4 | 4.0 |
DNA Helicases/*metabolism | 15 | 30.0 |
DNA Replication | 4 | 1.0 |
Substrate Specificity | 7 | 0.0 |
Werner Syndrome/*genetics | 19 | 63.0 |
Middle Aged | 5 | 0.0 |
Mutation/genetics | 4 | 0.0 |
Alleles | 5 | 0.0 |
DNA Helicases/*genetics | 10 | 22.0 |
DNA Mutational Analysis | 2 | 0.0 |
Molecular Sequence Data | 18 | 0.0 |
Base Sequence | 18 | 0.0 |
Catalysis | 6 | 0.0 |
DNA Primers | 5 | 0.0 |
*DNA-Binding Proteins | 4 | 0.0 |
Hela Cells | 10 | 0.0 |
Insects | 4 | 2.0 |
Protein-Serine-Threonine Kinases/*metabolism | 3 | 0.0 |
Recombinant Proteins/metabolism | 7 | 0.0 |
Werner Syndrome/*metabolism | 8 | 88.0 |
Amino Acid Sequence | 9 | 0.0 |
Cloning, Molecular | 6 | 0.0 |
DNA Helicases/chemistry/genetics/*metabolism | 3 | 75.0 |
Exodeoxyribonuclease V | 3 | 9.0 |
Exodeoxyribonucleases/*metabolism | 2 | 14.0 |
Mice | 12 | 0.0 |
Proliferating Cell Nuclear Antigen/metabolism | 2 | 0.0 |
Protein Structure, Tertiary | 10 | 0.0 |
Recombinant Proteins/isolation & purification/metabolism | 3 | 2.0 |
Sequence Homology, Amino Acid | 4 | 0.0 |
DNA/*genetics/metabolism | 2 | 10.0 |
Gene Deletion | 2 | 0.0 |
Male | 7 | 0.0 |
Transfection | 5 | 0.0 |
Cell Survival | 2 | 0.0 |
Dose-Response Relationship, Drug | 8 | 0.0 |
Enzyme Inhibitors/pharmacology | 6 | 0.0 |
Hydroxyurea/pharmacology | 3 | 5.0 |
Recombination, Genetic | 5 | 0.0 |
Time Factors | 4 | 0.0 |
DNA Repair/*genetics | 2 | 0.0 |
Macromolecular Substances | 4 | 0.0 |
Protein Subunits | 2 | 0.0 |
DNA-Binding Proteins/*metabolism | 3 | 0.0 |
Exonucleases/*metabolism | 4 | 36.0 |
Bloom Syndrome/genetics | 3 | 23.0 |
*Saccharomyces cerevisiae Proteins | 6 | 0.0 |
Werner Syndrome/genetics | 3 | 50.0 |
DNA/metabolism | 5 | 0.0 |
DNA Helicases/chemistry/*physiology | 2 | 100.0 |
DNA-Binding Proteins/physiology | 2 | 0.0 |
Endodeoxyribonucleases/chemistry/*metabolism | 2 | 33.0 |
Enzyme Activation | 4 | 0.0 |
Flap Endonucleases | 3 | 10.0 |
Recombinant Fusion Proteins/metabolism | 4 | 0.0 |
*Antigens, Nuclear | 5 | 3.0 |
DNA Helicases/*chemistry/*metabolism | 3 | 50.0 |
DNA-Binding Proteins/metabolism | 5 | 0.0 |
Dimerization | 5 | 0.0 |
Exonucleases/metabolism | 3 | 21.0 |
Kinetics | 8 | 0.0 |
Protein Binding | 9 | 0.0 |
Apoptosis/*genetics/physiology | 2 | 10.0 |
Camptothecin/pharmacology | 4 | 8.0 |
DNA Helicases/genetics/*metabolism | 6 | 27.0 |
*DNA Replication | 6 | 2.0 |
Flow Cytometry | 2 | 0.0 |
Immunohistochemistry | 3 | 0.0 |
Genes, Fungal | 2 | 1.0 |
Adenosinetriphosphatase/metabolism | 6 | 5.0 |
Apoptosis | 3 | 0.0 |
4-Nitroquinoline-1-oxide/pharmacology | 2 | 25.0 |
Cell Line | 13 | 0.0 |
In Situ Hybridization, Fluorescence | 2 | 0.0 |
DNA Helicases/genetics/metabolism/*physiology | 3 | 100.0 |
Werner Syndrome/*enzymology/genetics | 5 | 71.0 |
Adenosine Triphosphate/metabolism | 3 | 0.0 |
Cell Nucleus/metabolism | 2 | 0.0 |
Recombinant Proteins/genetics/metabolism | 2 | 0.0 |
*Recombination, Genetic | 2 | 0.0 |
Werner Syndrome/genetics/*metabolism | 2 | 66.0 |
Binding Sites | 7 | 0.0 |
DNA Helicases/chemistry/*metabolism | 4 | 57.0 |
DNA-Binding Proteins/*chemistry/genetics/*metabolism | 2 | 3.0 |
Fluorescent Antibody Technique, Indirect | 4 | 0.0 |
Precipitin Tests | 3 | 0.0 |
DNA, Complementary/metabolism | 3 | 0.0 |
Glutathione Transferase/metabolism | 2 | 0.0 |
Werner Syndrome/*genetics/metabolism | 2 | 66.0 |
Alternative Splicing | 2 | 0.0 |
Cell Division | 2 | 0.0 |
*Nucleic Acid Conformation | 2 | 2.0 |
Templates, Genetic | 2 | 1.0 |
Werner Syndrome/*enzymology | 5 | 83.0 |
Adult | 9 | 0.0 |
Aged | 4 | 0.0 |
Aged, 80 and over | 3 | 0.0 |
DNA Helicases/*physiology | 2 | 50.0 |
Sequence Analysis, DNA | 3 | 0.0 |
DNA Helicases/*genetics/*metabolism | 4 | 66.0 |
Peptide Mapping | 2 | 0.0 |
Signal Transduction | 2 | 0.0 |
Disease Models, Animal | 2 | 0.0 |
Polymorphism, Genetic | 2 | 0.0 |
DNA Primers/genetics | 2 | 0.0 |
DNA Topoisomerases, Type I/*metabolism | 2 | 7.0 |
DNA, Complementary/genetics | 2 | 0.0 |
RNA, Messenger/genetics/metabolism | 2 | 0.0 |
Down-Regulation | 2 | 0.0 |
*Polymorphism, Genetic | 2 | 0.0 |
DNA, Single-Stranded/metabolism | 2 | 3.0 |
Hydrolysis | 2 | 0.0 |
Mutagenesis, Site-Directed | 2 | 0.0 |
Chromosome Mapping/*methods | 2 | 1.0 |
Chromosome Mapping | 4 | 0.0 |
Gene Expression | 2 | 0.0 |
*Transcription, Genetic | 2 | 0.0 |
Werner Syndrome | 2 | 66.0 |
Werner Syndrome/*enzymology/*genetics | 2 | 100.0 |
Genetic Complementation Test | 2 | 0.0 |
Pedigree | 2 | 0.0 |
Homozygote | 2 | 0.0 |
Consanguinity | 2 | 0.0 |
Genetic Markers | 3 | 0.0 |
Adolescent | 2 | 0.0 |
*Chromosomes, Human, Pair 8 | 2 | 0.0 |
Lod Score | 2 | 0.0 |
Polymerase Chain Reaction | 2 | 0.0 |
Tumor Cells, Cultured | 2 | 0.0 |
Green Fluorescent Proteins | 2 | 0.0 |
Enzyme-Linked Immunosorbent Assay | 2 | 0.0 |
DNA Replication/*genetics | 2 | 3.0 |
Electrophoretic Mobility Shift Assay | 3 | 0.0 |