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Taipei Medical University

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Gene Symbol
Gene NameAliasesPrevious_Symbol

VHL

von Hippel-Lindau tumor suppressorVHL1von Hippel-Lindau syndrome


Gene VHL gene interaction
View Neighborhood Gene

Result number fewer <<<< << < ALL > >> >>> more

MeSH term
FrequencyCondition_Probility

Female

3010.0

Humans

7580.0

Pregnancy

90.0

Pregnancy Outcome

20.0

Adolescent

1000.0

Adult

2610.0

Aged

1300.0

Gene Expression Profiling/methods

22.0

Male

3030.0

Membrane Proteins/genetics/*metabolism

20.0

Middle Aged

2160.0

Neoplasm Proteins/genetics/metabolism

32.0

Oligonucleotide Array Sequence Analysis/methods

22.0

Prognosis

260.0

RNA, Messenger/genetics

60.0

RNA, Neoplasm/genetics

41.0

Research Support, Non-U.S. Gov't

3770.0

Reverse Transcriptase Polymerase Chain Reaction/methods

20.0

Survival Analysis

90.0

Up-Regulation

180.0

Carcinoma, Renal Cell/*genetics

3637.0

Endothelial Growth Factors/*genetics

52.0

Kidney Neoplasms/*genetics

4019.0

Ligases/*genetics

3534.0

*Loss of Heterozygosity

236.0

Lymphokines/*genetics

52.0

*Tumor Suppressor Proteins

27020.0

*Ubiquitin-Protein Ligases

26148.0

Vascular Endothelial Growth Factor A

341.0

Vascular Endothelial Growth Factors

330.0

Comparative Study

420.0

Hippel-Lindau Disease/complications/*pathology

3100.0

Adrenal Gland Neoplasms/genetics

932.0

Child

690.0

Diagnosis, Differential

311.0

*Gene Deletion

131.0

*Genes, Tumor Suppressor

11211.0

Germ-Line Mutation/*genetics

117.0

Heterozygote Detection

30.0

Hippel-Lindau Disease/*diagnosis/*genetics

6100.0

Phenotype

540.0

Pheochromocytoma/diagnosis/genetics

480.0

Mutation/*genetics

80.0

Pedigree

660.0

Proteins/*genetics

613.0

Animals

1400.0

Base Sequence/genetics

51.0

Cell Line

460.0

Conserved Sequence

40.0

Evolution, Molecular

30.0

Genes, Tumor Suppressor/*physiology

1816.0

Hela Cells

190.0

Hippel-Lindau Disease/*genetics

12896.0

Molecular Sequence Data

1190.0

Research Support, U.S. Gov't, P.H.S.

1390.0

Transcription Factors/metabolism

181.0

Tumor Cells, Cultured

1040.0

*Chromosomes, Human

23.0

*Mutation

521.0

Ovarian Neoplasms/*genetics/pathology

22.0

Age of Onset

151.0

Base Sequence

900.0

DNA Primers

210.0

Electron Transport Complex II

311.0

Family

51.0

Germ-Line Mutation

256.0

Multienzyme Complexes/*genetics

22.0

Oxidoreductases/*genetics

22.0

Polymerase Chain Reaction

880.0

Succinate Dehydrogenase/*genetics

624.0

Blotting, Western

230.0

Cell Hypoxia/physiology

1014.0

Cell Nucleus/*metabolism

51.0

Cytoplasm/metabolism

80.0

Enzyme Inhibitors/pharmacology

40.0

Green Fluorescent Proteins

80.0

Ligases/*metabolism

1314.0

Mice

600.0

Oxygen/*metabolism

64.0

Recombinant Fusion Proteins/genetics/metabolism

50.0

Transcription Factors/genetics/*metabolism

30.0

Ubiquitin/*metabolism

52.0

Prospective Studies

60.0

Risk Factors

170.0

Blotting, Northern

180.0

Carcinoma, Renal Cell/genetics

2057.0

Cyclin D1/*genetics

23.0

Gene Expression Profiling

70.0

Gene Expression Regulation, Neoplastic

311.0

Kidney Neoplasms/genetics

1825.0

Oligonucleotide Array Sequence Analysis

70.0

Oxygen/pharmacology

37.0

Transfection

530.0

Binding Sites

160.0

Carcinoma, Renal Cell/genetics/*metabolism/pathology

550.0

Genes, Tumor Suppressor

698.0

Immunoenzyme Techniques

110.0

Kidney Neoplasms/genetics/*metabolism/pathology

538.0

Luciferases/metabolism

30.0

Luminescent Proteins/metabolism

51.0

Mice, SCID

30.0

Monosaccharide Transport Proteins/metabolism

512.0

Plasmids

40.0

Recombinant Fusion Proteins

30.0

Transcription Factors/*metabolism

150.0

Transcription, Genetic

270.0

Ubiquitin-Protein Ligases

83.0

Carcinoma, Renal Cell/*genetics/metabolism/pathology

650.0

Down-Regulation

150.0

Kidney Neoplasms/*genetics/metabolism/pathology

646.0

Ligases/*physiology

220.0

Mice, Nude

150.0

Mutation

961.0

Protein Synthesis Inhibitors/pharmacology

20.0

Retroviridae/genetics

20.0

Fluorescein Angiography

1412.0

Fundus Oculi

66.0

Hemangioblastoma/*complications/diagnosis

2100.0

Hippel-Lindau Disease/*complications/*diagnosis/genetics

2100.0

Time Factors

210.0

Hemangioblastoma/*complications/pathology

2100.0

Hippel-Lindau Disease/*complications/pathology

3100.0

Hyperparathyroidism/*complications

250.0

Carcinoma, Renal Cell/*genetics/metabolism

640.0

CpG Islands/genetics

53.0

Immunohistochemistry

450.0

Kidney Neoplasms/*genetics/metabolism

725.0

Loss of Heterozygosity/genetics

75.0

Methylation

50.0

English Abstract

580.0

Hippel-Lindau Disease/*complications

29100.0

Paraganglioma/complications

2100.0

Cysteine Endopeptidases/metabolism

62.0

Hydrolysis

60.0

Multienzyme Complexes/metabolism

63.0

Proteasome Endopeptidase Complex

81.0

Amino Acid Sequence

600.0

Anoxia/metabolism

410.0

Crystallography, X-Ray

30.0

Hydrogen Bonding

31.0

Hydroxylation

82.0

Kinetics

80.0

Models, Molecular

120.0

Protein Binding

270.0

Protein Conformation

80.0

Sequence Alignment

90.0

Structure-Activity Relationship

40.0

Substrate Specificity

30.0

Transcription Factors/*chemistry/*metabolism

37.0

Adrenal Gland Neoplasms/*surgery

375.0

Adrenalectomy/*methods

3100.0

Pheochromocytoma/*surgery

266.0

Retrospective Studies

351.0

Peptide Synthases/*metabolism

39.0

Recombinant Proteins/metabolism

110.0

Spodoptera

20.0

Clinical Trials

40.0

Hippel-Lindau Disease/genetics

3583.0

Neoplasm Staging

190.0

Receptor Protein-Tyrosine Kinases/*antagonists & inhibitors

49.0

Tumor Suppressor Proteins/genetics

1116.0

Ubiquitin-Protein Ligases/genetics

947.0

Tumor Suppressor Proteins/*genetics

1914.0

Ubiquitin-Protein Ligases/*genetics

1851.0

Ligases/genetics/*physiology

342.0

3T3 Cells

30.0

COS Cells

110.0

Protein Structure, Tertiary

150.0

*Signal Transduction

50.0

Cell Membrane/metabolism

40.0

Carcinoma, Renal Cell/epidemiology/*genetics

266.0

*Epidemiology, Molecular

211.0

Kidney Neoplasms/epidemiology/*genetics

375.0

Aged, 80 and over

310.0

Child, Preschool

280.0

Cohort Studies

40.0

*Drosophila Proteins

141.0

*Germ-Line Mutation

245.0

Heterozygote

371.0

Multiple Endocrine Neoplasia Type 2a/genetics

723.0

Mutation, Missense

162.0

Pheochromocytoma/*genetics

2663.0

Proto-Oncogene Proteins/*genetics

70.0

Receptor Protein-Tyrosine Kinases/*genetics

82.0

Carcinoma, Renal Cell/*genetics/pathology

1954.0

Chromosomes, Human, Pair 3/*genetics

199.0

DNA Mutational Analysis

711.0

DNA, Neoplasm/chemistry/genetics

43.0

Family Health

100.0

Karyotyping

140.0

Kidney Neoplasms/*genetics/pathology

2432.0

Ligases/genetics

1437.0

Loss of Heterozygosity

334.0

Microsatellite Repeats

161.0

Point Mutation

221.0

*Translocation, Genetic

40.0

Hippel-Lindau Disease/*complications/*genetics

3100.0

In Situ Hybridization, Fluorescence

170.0

Magnetic Resonance Imaging

434.0

*Amino Acid Substitution

22.0

Codon/genetics

20.0

Hippel-Lindau Disease/diagnosis/*genetics

1694.0

Hypertension/etiology

36.0

*Mutation, Missense

61.0

Paraganglioma, Extra-Adrenal/*genetics

342.0

*Point Mutation

90.0

Chromosomes, Human, Pair 3

3115.0

Erythropoietin/blood

46.0

Ligases/*genetics/physiology

266.0

Linkage (Genetics)

210.0

Receptors, Growth Factor/*antagonists & inhibitors

317.0

Receptors, Vascular Endothelial Growth Factor

71.0

Ligases/*genetics/metabolism

425.0

RNA, Messenger/biosynthesis

50.0

Tomography, X-Ray Computed

334.0

*DNA Methylation

253.0

DNA, Neoplasm/metabolism

21.0

Fluorescent Antibody Technique, Indirect

60.0

*Gene Expression Regulation, Neoplastic

171.0

Gene Silencing

82.0

Infant

100.0

Ligases/genetics/metabolism

28.0

*Promoter Regions (Genetics)

70.0

RNA, Messenger/metabolism

150.0

Reverse Transcriptase Polymerase Chain Reaction

140.0

Carcinoma, Renal Cell/*pathology

212.0

Kidney Neoplasms/*pathology

39.0

DNA-Binding Proteins/*genetics

30.0

Transcription Factors/*genetics

50.0

Translocation, Genetic

81.0

Cerebellar Neoplasms/*genetics

842.0

Chromosome Aberrations

50.0

DNA, Neoplasm/*genetics

73.0

Exons/genetics

120.0

Hemangioblastoma/*genetics

8100.0

Sequence Deletion/*genetics

32.0

Deferoxamine/pharmacology

49.0

*Trans-Activation (Genetics)

30.0

*Transcription Factors

211.0

Cell Transformation, Neoplastic/genetics

82.0

Hippel-Lindau Disease/complications/*genetics

14100.0

Pancreatic Neoplasms/*genetics

55.0

Blotting, Southern

150.0

Carcinoma, Renal Cell/*genetics/*pathology

375.0

DNA Methylation

172.0

DNA, Neoplasm/genetics

192.0

Kidney Neoplasms/*genetics/*pathology

342.0

Mutation/genetics

80.0

Hippel-Lindau Disease/complications/*genetics/pathology

3100.0

Proteins/genetics

324.0

Repressor Proteins/genetics

32.0

Adenocarcinoma/*genetics

42.0

DNA Primers/chemistry

70.0

Gene Deletion

301.0

Genes, ras/*genetics

22.0

Polymerase Chain Reaction/*methods

30.0

Sensitivity and Specificity

90.0

Adrenal Gland Neoplasms/diagnosis/*genetics

2100.0

Genetic Screening

141.0

Paraganglioma/genetics

466.0

Pheochromocytoma/diagnosis/*genetics

2100.0

Angiogenesis Inhibitors/therapeutic use

26.0

Hippel-Lindau Disease/diagnosis/*genetics/therapy

2100.0

Self-Help Groups

218.0

Transcription Factors/genetics

70.0

Breast Neoplasms/*genetics/pathology

41.0

Disease Progression

120.0

*Gene Expression Profiling

40.0

Lymphatic Metastasis

20.0

Multigene Family

30.0

*Genes, BRCA1

20.0

Carcinogens

45.0

Ligases/genetics/*metabolism

510.0

Rats

350.0

Rats, Inbred F344

51.0

Cell Cycle Proteins/metabolism

41.0

*Cullin Proteins

1117.0

Macromolecular Substances

90.0

Mutagenesis, Site-Directed

40.0

Protein Folding

40.0

Asian Continental Ancestry Group/*genetics

20.0

Carcinoma, Non-Small-Cell Lung/*genetics

22.0

Carcinoma, Squamous Cell/*genetics

84.0

Lung Neoplasms/*genetics

52.0

*Alleles

80.0

Hemangioblastoma/genetics

9100.0

Models, Genetic

120.0

Point Mutation/*genetics

72.0

Polymorphism, Single-Stranded Conformational

592.0

Adrenal Gland Neoplasms/*genetics

1756.0

*Chromosome Deletion

212.0

*Chromosomes, Human, Pair 11

30.0

DNA, Neoplasm/analysis

172.0

Multiple Endocrine Neoplasia/genetics

215.0

Nucleic Acid Hybridization

60.0

Syndrome

100.0

Keratin/analysis

20.0

Stromal Cells/chemistry/pathology

29.0

Tumor Markers, Biological/analysis

20.0

Adrenalectomy

612.0

Laparoscopy

38.0

Gene Library

20.0

RNA, Messenger/biosynthesis/genetics

50.0

Recombinant Fusion Proteins/physiology

20.0

Genotype

390.0

Amino Acid Substitution

50.0

Cell Hypoxia/*physiology

23.0

Recombinant Fusion Proteins/metabolism

70.0

Spectrum Analysis, Mass

30.0

DNA, Neoplasm/analysis/genetics

55.0

Multiple Endocrine Neoplasia Type 2a/*genetics

311.0

Adrenal Gland Neoplasms/genetics/pathology

240.0

*Chromosome Aberrations

61.0

Chromosome Mapping

370.0

Crosses, Genetic

20.0

Mice, Inbred C57BL

50.0

Mice, Knockout

70.0

Pheochromocytoma/genetics/pathology

480.0

Infant, Newborn

70.0

Brain Neoplasms/*genetics

21.0

Carcinoma, Hepatocellular/genetics

27.0

CpG Islands/*genetics

33.0

DNA-Binding Proteins/metabolism

40.0

Liver Neoplasms/genetics

29.0

Neoplasm Proteins/*metabolism

20.0

Nuclear Proteins/metabolism

40.0

Promoter Regions (Genetics)

170.0

Sex Factors

40.0

Tumor Suppressor Proteins/metabolism

21.0

*Acid Anhydride Hydrolases

125.0

*Chromosomes, Human, Pair 3

4913.0

Neoplasm Proteins/genetics

102.0

Polymerase Chain Reaction/methods

141.0

Analysis of Variance

20.0

Immunohistochemistry/methods

20.0

Ki-67 Antigen/analysis

31.0

Neovascularization, Pathologic

61.0

Sequence Analysis, DNA

180.0

Survival Rate

100.0

Tumor Markers, Biological/*analysis

20.0

Alleles

340.0

Chromosome Deletion

101.0

Frameshift Mutation

61.0

Adrenal Gland Neoplasms/*etiology

2100.0

Neoplasms, Multiple Primary/*etiology

266.0

Pheochromocytoma/*etiology

2100.0

Ubiquitin/metabolism

31.0

Vascular Endothelial Growth Factor Receptor-1

20.0

*Antigens, Neoplasm

21.0

Neurofibromatosis 2/genetics

222.0

Molecular Biology

93.0

Bladder Neoplasms/genetics

216.0

Cadherins/genetics

47.0

Genetic Screening/methods

64.0

Glutathione Transferase/genetics

20.0

Isoenzymes/genetics

20.0

O(6)-Methylguanine-DNA Methyltransferase/genetics

27.0

Prostatic Neoplasms/genetics

24.0

Urogenital Neoplasms/*genetics

2100.0

Adenocarcinoma/*genetics/pathology

33.0

*Cell Hypoxia

57.0

Cobalt/pharmacology

48.0

DNA-Binding Proteins/*metabolism

140.0

Nuclear Proteins/*metabolism

152.0

DNA, Complementary/metabolism

70.0

Electrophoresis, Polyacrylamide Gel

60.0

Glutathione Transferase/metabolism

20.0

Immunoblotting

70.0

Plasmids/metabolism

80.0

Precipitin Tests

90.0

Sequence Homology, Amino Acid

170.0

Two-Hybrid System Techniques

30.0

Age Factors

80.0

Hippel-Lindau Disease/*complications/diagnosis

5100.0

Cell Hypoxia

106.0

DNA-Binding Proteins/*genetics/metabolism

20.0

Helix-Loop-Helix Motifs

20.0

Nuclear Proteins/*genetics/metabolism

32.0

Trans-Activators/metabolism

30.0

Transcription Factors/*genetics/metabolism

30.0

*Endolymphatic Sac/pathology/radiography

2100.0

Hippel-Lindau Disease/diagnosis/*genetics/pathology

2100.0

Cerebellum/pathology

413.0

Genes, Dominant

60.0

Adrenal Gland Neoplasms/diagnosis/genetics

3100.0

Hippel-Lindau Disease/classification/diagnosis/*genetics

2100.0

Hippel-Lindau Disease/complications/metabolism/*pathology

2100.0

Neoplasm Proteins/metabolism

20.0

Treatment Outcome

140.0

Tumor Markers, Biological/metabolism

51.0

Incidence

90.0

Databases, Factual

20.0

Neoplasms/genetics

54.0

Central Nervous System Neoplasms/*genetics/pathology

220.0

Hemangioblastoma/*genetics/pathology

3100.0

Cells, Cultured

190.0

Fungal Proteins/metabolism

31.0

Gene Expression Regulation

100.0

In Vitro

20.0

Nuclear Proteins/genetics/*metabolism

82.0

Oxygen/metabolism

94.0

Repressor Proteins/genetics/*metabolism

21.0

Saccharomyces cerevisiae

20.0

*Saccharomyces cerevisiae Proteins

60.0

Signal Transduction/physiology

20.0

Trans-Activation (Genetics)

70.0

Carcinoma, Renal Cell/genetics/metabolism

457.0

Endothelial Growth Factors/*biosynthesis/genetics

54.0

Kidney Neoplasms/genetics/metabolism

216.0

*Ligases

16686.0

Lymphokines/*biosynthesis/genetics

43.0

Trans-Activators/*biosynthesis/genetics

310.0

Ubiquitins/metabolism

107.0

Adenocarcinoma, Clear Cell/*genetics/pathology

233.0

*Gene Silencing

42.0

Neoplasm Proteins/*genetics

30.0

Chromosomes, Human, Pair 13

21.0

*Chromosomes, Human, Pair 17

30.0

*Chromosomes, Human, Pair 9

20.0

Protein p16/genetics

55.0

Protein p53/genetics

31.0

Age Distribution

20.0

Hippel-Lindau Disease/*complications/epidemiology/pathology

2100.0

Laser Coagulation

212.0

Case-Control Studies

40.0

Paraffin Embedding

20.0

Tumor Markers, Biological

71.0

Combined Modality Therapy

40.0

Hippel-Lindau Disease/complications

6100.0

CHO Cells

20.0

Cell Fusion

41.0

Clone Cells

20.0

DNA

40.0

DNA-Binding Proteins/*physiology

30.0

Flow Cytometry

30.0

Gene Expression Regulation/*physiology

20.0

Genetic Complementation Test

30.0

Hamsters

20.0

Genes, Tumor Suppressor/genetics/*physiology

375.0

Hemangioblastoma/*genetics/pathology/surgery

2100.0

Hippel-Lindau Disease/*genetics/pathology/surgery

3100.0

Mutation, Missense/genetics

42.0

Magnetic Resonance Spectroscopy

20.0

Research Support, U.S. Gov't, Non-P.H.S.

120.0

Cell Nucleus/metabolism

100.0

CpG Islands

72.0

Exons

210.0

Introns

60.0

Polymorphism, Genetic

170.0

Carrier Proteins/*genetics

40.0

DNA-Binding Proteins/genetics

40.0

Nuclear Proteins/genetics

31.0

Proteins/*metabolism

101.0

SKP Cullin F-Box Protein Ligases

37.0

Variation (Genetics)

60.0

Chromosomes, Human, Pair 6

21.0

Chromosomes, Human, Pair 9

42.0

Pheochromocytoma/genetics

1040.0

Cysteine Endopeptidases

24.0

*Hippel-Lindau Disease

2100.0

Carcinoma, Renal Cell/pathology

330.0

Kidney Neoplasms/pathology

325.0

Hippel-Lindau Disease/*complications/diagnosis/*genetics

2100.0

Cell Division/drug effects

40.0

Mice, Inbred BALB C

50.0

*Neoplasm Proteins

81.0

Neoplasm Transplantation

60.0

Neovascularization, Pathologic/genetics

412.0

Gene Frequency

70.0

Polymorphism, Restriction Fragment Length

220.0

Cercopithecus aethiops

50.0

Protein Binding/drug effects

30.0

Proteins/genetics/*metabolism

132.0

Deoxyribonuclease HpaII/metabolism

215.0

Angiomatosis/genetics

2100.0

Penetrance

21.0

Follow-Up Studies

240.0

Risk Assessment

30.0

*Hippel-Lindau Disease/diagnosis/genetics/therapy

2100.0

Cell Hypoxia/genetics

529.0

Carcinoma, Renal Cell/metabolism/pathology

250.0

Cell Communication

31.0

Cell Division

140.0

Proteins/chemistry/genetics/*metabolism

44.0

Chromatography, High Pressure Liquid

30.0

Genes, Tumor Suppressor/*genetics

3812.0

Nucleic Acid Denaturation

33.0

RNA Splice Sites/genetics

21.0

Reproducibility of Results

60.0

Temperature

50.0

Carcinoma/*genetics

32.0

*Cell Cycle Proteins

60.0

Adenocarcinoma, Clear Cell/genetics/pathology

240.0

Carcinoma, Papillary/genetics/pathology

233.0

Chromosomes, Human, Pair 3/genetics

1813.0

Hippel-Lindau Disease/complications/diagnosis/*genetics

5100.0

Neoplasm Invasiveness

40.0

Patient Care Team

211.0

Postoperative Complications/diagnosis

220.0

Reoperation

32.0

*Gene Expression Regulation, Enzymologic

20.0

Genes, Reporter

50.0

Ubiquitin-Protein Ligases/metabolism

24.0

Cell Adhesion

20.0

Gene Expression Regulation, Neoplastic/drug effects

20.0

Restriction Mapping

70.0

Cloning, Molecular

200.0

Insects

21.0

Ligases/metabolism

23.0

Rats, Sprague-Dawley

50.0

Transcription Factors/*chemistry/metabolism

48.0

Kidney Neoplasms/genetics/metabolism/pathology

342.0

Protein Biosynthesis

90.0

Proteins/genetics/*physiology

107.0

DNA-Binding Proteins/genetics/*metabolism

60.0

*Genetic Screening

42.0

Japan

90.0

RNA, Messenger/analysis

60.0

Genes, Tumor Suppressor/genetics

2515.0

Loss of Heterozygosity/*genetics

55.0

Adrenal Gland Neoplasms/complications/genetics

2100.0

*Down-Regulation

41.0

Neoplasms/*genetics

93.0

Pheochromocytoma/complications/genetics

3100.0

Proteins/genetics/metabolism/*physiology

25.0

Disease Models, Animal

60.0

Cell Line, Tumor

120.0

Enzyme Activation

20.0

Disease Susceptibility

30.0

Kidney Neoplasms/genetics/surgery

266.0

Nephrectomy

78.0

Endothelial Growth Factors/*metabolism

20.0

Hippel-Lindau Disease/genetics/*metabolism/pathology

2100.0

Lymphokines/*metabolism

20.0

Protein p53/*metabolism

30.0

Nerve Tissue Proteins/genetics

20.0

Neurofibromatosis 1/genetics

310.0

Proto-Oncogene Proteins/genetics

81.0

Receptor Protein-Tyrosine Kinases/genetics

106.0

Adenocarcinoma, Clear Cell/genetics/metabolism/pathology

233.0

Kidney/metabolism

51.0

Carbonic Anhydrases/genetics

333.0

Carcinoma, Renal Cell/genetics/*metabolism

545.0

Hydrogen-Ion Concentration

20.0

Chromosome Aberrations/genetics

43.0

In Situ Hybridization, Fluorescence/methods

22.0

Carcinoma, Renal Cell/genetics/*pathology

350.0

Kidney Neoplasms/genetics/*pathology

325.0

Ligases/metabolism/*physiology

233.0

Subcellular Fractions/metabolism

20.0

*Intracellular Signaling Peptides and Proteins

40.0

Leukemia/genetics

24.0

Mutagenesis

20.0

Phosphorylation

60.0

Ubiquitins/*metabolism

63.0

Hippel-Lindau Disease/*diagnosis

2100.0

Endothelium, Vascular/cytology

20.0

Microscopy, Confocal

40.0

Microscopy, Fluorescence

50.0

Nuclear Localization Signal

22.0

Brain/pathology

41.0

Cerebellar Neoplasms/diagnosis/surgery

2100.0

Hemangioblastoma/diagnosis/surgery

2100.0

Spinal Cord/pathology

56.0

Amino Acid Substitution/*genetics

23.0

Arginine/genetics

21.0

Genetic Predisposition to Disease/genetics

40.0

Polymorphism, Genetic/genetics

20.0

Adenocarcinoma, Clear Cell/genetics

430.0

Protein Isoforms

20.0

Kidney Neoplasms/metabolism

420.0

*Protein Biosynthesis

71.0

Cell Differentiation

40.0

Models, Biological

50.0

*Anesthesia, Epidural

218.0

Neoplasm Recurrence, Local/surgery

250.0

Salvage Therapy

22.0

Adenoviridae/genetics

20.0

*Gene Therapy

30.0

Gene Transfer Techniques

20.0

Catecholamines/blood/urine

2100.0

Polycythemia/*genetics

218.0

Retinal Neoplasms/genetics

266.0

Proteins/*genetics/metabolism

41.0

Bayes Theorem

23.0

Prevalence

70.0

Probability

20.0

Retinal Neoplasms/*complications/pathology

2100.0

Mice, Mutant Strains

20.0

Carcinoma/genetics

26.0

Chromosome Painting

24.0

DNA/metabolism

30.0

Hybrid Cells

50.0

Neoplasms, Experimental

25.0

*Anoxia

27.0

Endothelial Growth Factors/metabolism

42.0

In Situ Hybridization

110.0

Lymphokines/metabolism

41.0

RNA/metabolism

30.0

*Chromosomes, Human, Pair 1

20.0

Signal Transduction

50.0

Radiosurgery

240.0

DNA/analysis

50.0

Hippel-Lindau Disease/complications/*diagnosis/genetics

3100.0

Cell Transformation, Neoplastic/genetics/pathology

29.0

Kidney/pathology

74.0

Chromosomes, Human, Pair 10/genetics

22.0

Pancreatic Neoplasms/*genetics/pathology

25.0

Chromosomes, Human, Pair 1/genetics

31.0

DNA/genetics/isolation & purification

31.0

Genes, p53/genetics

41.0

Microtubule-Associated Proteins/metabolism

32.0

Proteins/*genetics/physiology

45.0

Neoplasm Recurrence, Local

61.0

Bladder Neoplasms/*genetics

22.0

Phylogeny

20.0

Endothelial Growth Factors/biosynthesis/genetics

312.0

Lymphokines/biosynthesis/genetics

310.0

RNA, Messenger/genetics/metabolism

50.0

Multiple Endocrine Neoplasia Type 2a/complications

2100.0

Pheochromocytoma/complications/*surgery

2100.0

Antineoplastic Combined Chemotherapy Protocols/therapeutic use

20.0

Biopsy

40.0

Hippel-Lindau Disease/*complications/genetics

7100.0

Oncogenes

20.0

Organ Specificity

40.0

Sequence Deletion

90.0

Immunoprecipitation

20.0

Microsatellite Repeats/genetics

51.0

Promoter Regions (Genetics)/genetics

50.0

Proto-Oncogene Protein c-met/genetics

316.0

Gene Expression

80.0

*Nerve Tissue Proteins

20.0

*Endolymphatic Sac

3100.0

Molecular Biology/methods

27.0

Risk

40.0

Drosophila

20.0

Adrenal Gland Neoplasms/*genetics/pathology

228.0

Genetic Markers

280.0

Pheochromocytoma/*genetics/pathology

250.0

Retinal Neoplasms/*genetics/pathology

240.0

Stromal Cells/metabolism/pathology

24.0

Genetic Predisposition to Disease

110.0

*Proto-Oncogene Proteins

30.0

Carcinoma, Renal Cell/*genetics/pathology/secondary

2100.0

Neoplasms, Multiple Primary/*genetics/pathology

220.0

Adenocarcinoma, Clear Cell/*genetics

787.0

*Hippel-Lindau Disease/diagnosis/genetics

2100.0

Proteins/genetics/physiology

58.0

Cell Line, Transformed

50.0

Protein Processing, Post-Translational

50.0

Cell Extracts

21.0

Proteins/*chemistry/genetics/*metabolism

27.0

Carcinogenicity Tests

22.0

Species Specificity

20.0

Visual Acuity

42.0

Genes, Tumor Suppressor/physiology

24.0

Transduction, Genetic

20.0

Epithelial Cells/cytology/metabolism

23.0

Mitochondria/*metabolism

31.0

Fluorescent Antibody Technique

40.0

Proteins/*genetics/*metabolism

22.0

Carcinoma, Renal Cell/genetics/pathology

666.0

Hemangioblastoma/genetics/pathology

2100.0

Hippel-Lindau Disease/*genetics/pathology

6100.0

Netherlands

31.0

*Sequence Deletion

71.0

Cell Cycle Proteins/*genetics

31.0

Chromosomes, Human, Pair 7

31.0

Germ-Line Mutation/genetics

45.0

Transforming Growth Factor alpha/genetics

27.0

Neoplasm Metastasis

60.0

Nephrectomy/*methods

240.0

Ultrasonography

22.0

Kidney, Cystic/genetics

240.0

Tuberous Sclerosis/genetics

27.0

Base Pair Mismatch

21.0

*Chromosome Mapping

40.0

Adenoma, Oxyphilic/genetics/pathology

2100.0

DNA, Complementary/genetics

60.0

Genetic Markers/genetics

20.0

Sequence Tagged Sites

20.0

Carcinoma, Renal Cell/*metabolism

313.0

Kidney Neoplasms/*metabolism

414.0

Carrier Proteins/*metabolism

20.0

Kidney Neoplasms/diagnosis

250.0

Kidney Neoplasms/diagnosis/genetics

2100.0

Adenosine Triphosphate/metabolism

20.0

Cell Compartmentation

41.0

Cell Cycle Proteins/*metabolism

41.0

Luminescent Proteins/genetics/metabolism

21.0

RNA Polymerase II/metabolism

43.0

Hippel-Lindau Disease/*surgery

2100.0

Neoplasms, Multiple Primary/diagnosis

266.0

Chromosomes, Human, Pair 17

41.0

Acute Disease

20.0

Haplotypes

60.0

Carcinoma, Renal Cell/*complications

2100.0

Kidney Neoplasms/*complications

266.0

Renal Dialysis

20.0

Hippel-Lindau Disease/*genetics/radiography

2100.0

Genetic Counseling

31.0

Hippel-Lindau Disease/diagnosis/epidemiology/*genetics

2100.0

Morbidity

35.0

DNA Fingerprinting

21.0

Chromosomes, Human, Pair 1/*genetics

31.0

Cerebellar Neoplasms/diagnosis

266.0

Hemangioma/diagnosis

250.0

Retinal Neoplasms/diagnosis

2100.0

*Databases, Factual

23.0

Diagnostic Imaging

39.0

Gene Expression Regulation, Developmental

40.0

Angiogenesis Inhibitors/*therapeutic use

34.0

Transplantation, Heterologous

30.0

Amino Acid Substitution/genetics

20.0

Endothelial Growth Factors/genetics

22.0

Lymphokines/genetics

22.0

Repressor Proteins/chemistry/genetics/metabolism

211.0

Sequence Deletion/genetics

21.0

Proteins/*physiology

31.0

Saccharomyces cerevisiae/metabolism

32.0

DNA Mutational Analysis/methods

41.0

Neoplasms/*genetics/metabolism

26.0

Severity of Illness Index

70.0

Gene Expression Regulation, Neoplastic/*genetics

21.0

DNA Primers/genetics

60.0

Patient Care Planning

213.0

Visual Fields

23.0

Carrier Proteins/metabolism

30.0

Molecular Weight

30.0

Codon/*genetics

23.0

Cosmids/genetics

23.0

*Disease Models, Animal

20.0

Mice, Transgenic

30.0

Occupational Exposure

22.0

United States

30.0

Chromosome Aberrations/*genetics

32.0

Chromosome Disorders

82.0

Multiple Endocrine Neoplasia Type 1/*genetics

21.0

Tumor Markers, Biological/genetics

22.0

*Microsatellite Repeats

20.0

Predictive Value of Tests

40.0

*Chromosomes, Human, Pair 8

31.0

Genes, p16

22.0

Mouth Neoplasms/*genetics

48.0

Homozygote

70.0

*Polymorphism, Restriction Fragment Length

40.0

Sequence Homology, Nucleic Acid

40.0

Neovascularization, Pathologic/*genetics

49.0

Receptor Protein-Tyrosine Kinases/metabolism

20.0

Alternative Splicing

30.0

Binding Sites/genetics

20.0

Laryngectomy/*methods

266.0

Vascular Endothelial Growth Factor A/genetics/metabolism

28.0

Hemangioma/etiology

375.0

Protein Structure, Secondary

30.0

Recombinant Proteins/genetics/metabolism

20.0

Adrenal Gland Neoplasms/*complications/surgery

266.0

Catecholamines/urine

216.0

Hippel-Lindau Disease/*complications/diagnosis/genetics

4100.0

Pheochromocytoma/*complications/surgery

2100.0

Tissue Distribution

50.0

Adenocarcinoma/genetics/pathology

24.0

Carcinoma/*genetics/pathology

23.0

Endolymphatic Sac/*pathology

2100.0

Hemangioblastoma/*complications/surgery

2100.0

Neoplasms, Multiple Primary

213.0

Retinal Neoplasms/complications

2100.0

Proto-Oncogenes/genetics

26.0

Apoptosis

30.0

In Situ Nick-End Labeling

30.0

Hippel-Lindau Disease/*genetics/physiopathology

2100.0

Microscopy, Electron

20.0

Iron Chelating Agents/pharmacology

28.0

Trichloroethylene/*adverse effects

250.0

Endothelial Growth Factors/*genetics/metabolism

24.0

*Gene Expression

40.0

Lymphokines/*genetics/metabolism

24.0

Hemangioma/genetics

3100.0

Nephrectomy/methods

228.0

von Willebrand Factor/analysis

20.0

Tumor Cells, Cultured/transplantation

26.0

Cell Cycle

30.0

S-Phase Kinase-Associated Proteins

22.0

Gene Expression Regulation/genetics

21.0

Tumor Suppressor Proteins/genetics/*metabolism

58.0

Ubiquitin-Protein Ligases/genetics/*metabolism

526.0

Up-Regulation/genetics

22.0

Surface Properties

21.0

Cerebellar Neoplasms/genetics

541.0

Kidney Neoplasms/genetics/pathology

350.0

Open Reading Frames

50.0

Cross-Sectional Studies

20.0

England/epidemiology

23.0

DNA, Neoplasm/*analysis

21.0

Great Britain/epidemiology

32.0

Smoking

20.0

Statistics, Nonparametric

20.0

Cerebellum/metabolism

24.0

Embryo/metabolism

31.0

Genes, ras

31.0

Protein p53/physiology

22.0

Protein-Tyrosine-Phosphatase/genetics

26.0

Hippel-Lindau Disease/genetics/metabolism

2100.0

Glucose/metabolism

20.0

France/epidemiology

21.0

Genes, Tumor Suppressor/*genetics/physiology

250.0

Adenocarcinoma, Clear Cell/chemically induced/*genetics/pathology

2100.0

Kidney Neoplasms/chemically induced/*genetics/pathology

266.0

Rats, Wistar

30.0

Smoking/adverse effects

20.0

Angiography

24.0

Recurrence

30.0

Hippel-Lindau Disease/genetics/pathology

266.0

Tumor Suppressor Proteins/*physiology

39.0

Postoperative Complications

32.0

Carcinoma, Renal Cell/*enzymology/genetics/pathology

266.0

Cell Membrane/enzymology

20.0

Kidney Neoplasms/*enzymology/genetics/pathology

250.0

Esophageal Neoplasms/*genetics

22.0

Eye Neoplasms/genetics

323.0

Cytosol/metabolism

30.0

RNA Interference

51.0

Carcinoma, Renal Cell/chemically induced/*genetics

4100.0

Diethylnitrosamine/analogs & derivatives

2100.0

Kidney Neoplasms/chemically induced/*genetics

583.0

Tuberous Sclerosis/*genetics

22.0

Chromosomes, Human, Pair 5

21.0

Carcinoma, Renal Cell/diagnosis/*genetics

375.0

Kidney Neoplasms/diagnosis/*genetics

350.0

Antigens, CD31/metabolism

22.0

*Polymorphism, Single-Stranded Conformational

21.0

Base Pair Mismatch/genetics

24.0

Twins, Monozygotic

22.0

Cell Transformation, Neoplastic/*genetics

31.0

Muscle Proteins/genetics

22.0

Chromosomes, Human, Pair 8

32.0

*Genetic Heterogeneity

21.0

Microsatellite Repeats/*genetics

20.0

Protein-Tyrosine Kinase/*metabolism

20.0

Neoplasms, Multiple Primary/*genetics

410.0

Epidermal Growth Factor/pharmacology

20.0

*Peptide Elongation Factors

216.0

Head and Neck Neoplasms/*genetics

34.0

Rats, Mutant Strains

23.0

*Nephrectomy

211.0

Decision Making

22.0

Liver Neoplasms/secondary

23.0

Half-Life

20.0

Kidney Neoplasms/genetics/*metabolism

325.0

Carcinoma, Renal Cell/*surgery

3100.0

Graft Survival

20.0

Carcinoma, Renal Cell/*metabolism/pathology

316.0

Epithelium/metabolism

20.0

Kidney Neoplasms/*metabolism/pathology

26.0

*DNA Mutational Analysis

31.0

Carcinoma, Renal Cell/classification/*genetics/pathology

2100.0

Kidney Neoplasms/classification/*genetics/pathology

266.0

Enzyme-Linked Immunosorbent Assay

40.0

Genetic Vectors

30.0

Tumor Suppressor Proteins/*genetics/metabolism

411.0

Ubiquitin-Protein Ligases/*genetics/metabolism

436.0

Adenocarcinoma, Follicular/*genetics/mortality

2100.0

Thyroid Neoplasms/*genetics/mortality

240.0

DNA/genetics

40.0

Adenoma/*genetics/pathology

311.0

Caenorhabditis elegans

44.0

Genes, Retinoblastoma

22.0

Cell Division/physiology

30.0

Kidney Neoplasms/*surgery

2100.0

Gene Expression Regulation, Neoplastic/physiology

21.0

Anoxia

22.0

Proportional Hazards Models

20.0

*CpG Islands

22.0

Embryonic and Fetal Development/*genetics

22.0

*Nerve Growth Factors

21.0

Nerve Tissue Proteins/*genetics

20.0

Repressor Proteins/*genetics

41.0

DNA, Neoplasm/*analysis/genetics

213.0

Genes, p53/*genetics

20.0

Kidney

20.0

DNA/*analysis

31.0

Hippel-Lindau Disease/*diagnosis/genetics

4100.0

Asian Continental Ancestry Group/genetics

20.0

European Continental Ancestry Group/genetics

20.0

Carcinoma, Renal Cell/epidemiology/genetics

2100.0

Cerebellar Neoplasms/etiology/*genetics

2100.0

Hemangioblastoma/etiology/*genetics

2100.0

Transcription, Genetic/genetics

20.0

Cytoplasm/chemistry

21.0

Liver/metabolism

20.0

Proteins/isolation & purification/*metabolism

26.0

Life Tables

21.0

Brain Neoplasms/genetics

211.0

Radionuclide Imaging

214.0

Proteins/metabolism

20.0

Abnormalities, Multiple/*genetics

20.0

Pheochromocytoma/complications/*genetics

375.0

RNA, Neoplasm/genetics/metabolism

21.0

Europe/epidemiology

22.0

*Genetic Predisposition to Disease

20.0

Internet

22.0

Carrier Proteins/biosynthesis/genetics/*metabolism

225.0

Hemangioblastoma

2100.0

Carcinoma, Renal Cell/metabolism/*pathology

228.0

Kidney Neoplasms/metabolism/*pathology

211.0

*Proto-Oncogenes

20.0

Transcription Factors/chemistry/*genetics/metabolism

24.0

Genes, APC

22.0

Colorectal Neoplasms/*genetics/pathology

33.0

Europe

20.0

*Heterozygote

20.0

Codon

20.0

Multiple Endocrine Neoplasia Type 2b/genetics

216.0

Hemangioblastoma/pathology

266.0

Hippel-Lindau Disease/*pathology

480.0

Endothelial Growth Factors/genetics/metabolism

24.0

Nuclear Proteins/*genetics

30.0

Thyroid Neoplasms/genetics

27.0

Transcription Factors/*physiology

20.0

*Transcription, Genetic

20.0

Repetitive Sequences, Nucleic Acid

20.0

Carcinoma, Renal Cell

327.0

Fatal Outcome

20.0

Adrenal Gland Neoplasms/complications/*genetics

266.0

DNA, Complementary

20.0

Nasopharyngeal Neoplasms/*genetics

29.0

*Founder Effect

21.0

Germany

20.0

Kidney Neoplasms

316.0

DNA Probes

60.0

Carcinoma, Papillary/genetics

320.0

Germ Cells

210.0

Molecular Structure

20.0

Ca(2+)-Transporting ATPase/*genetics

311.0

*Magnetic Resonance Imaging

42.0

*Linkage (Genetics)

30.0

Models, Chemical

20.0

Hemangioblastoma/*diagnosis

2100.0

Preoperative Care

21.0

Tumor Suppressor Proteins/genetics/*physiology

214.0

Ubiquitin-Protein Ligases/genetics/*physiology

2100.0

Neoplastic Syndromes, Hereditary/*genetics

37.0

Retinal Diseases/genetics

218.0

Cytoplasm/*metabolism

32.0

China

30.0

DNA/chemistry/genetics

20.0

*Proteasome Endopeptidase Complex

23.0

*Deoxyribonucleases, Type II Site-Specific

23.0

*Phenotype

20.0

Electrophoresis, Gel, Pulsed-Field

20.0

Chronic Disease

20.0

Paraganglioma/*genetics

320.0

DNA, Satellite/genetics

21.0

*Polymorphism, Genetic

30.0

*Repetitive Sequences, Nucleic Acid

20.0

Carcinoma, Renal Cell/complications/*genetics

2100.0

Kidney Neoplasms/complications/*genetics

228.0

Cosmids

20.0

Chromosome Banding

30.0

Spain

20.0

Visual Acuity/*physiology

225.0

Lod Score

60.0

Nuclear Proteins/*physiology

21.0

Ubiquitin-Protein Ligases/*physiology

228.0

Fibronectins/metabolism

21.0

Vascular Endothelial Growth Factor A/metabolism

21.0

Chromosome Fragile Sites

21.0

*Chromosome Fragility

21.0

Angiomatosis/*genetics

7100.0

*Diagnostic Imaging

225.0

Anoxia/*metabolism

23.0

Tumor Suppressor Proteins/*metabolism

66.0

Ubiquitin-Protein Ligases/*metabolism

416.0

Angiomatosis/*diagnosis

2100.0

Gadolinium/diagnostic use

212.0

Introns/genetics

20.0

*Polymorphism, Single Nucleotide

20.0

Hyperplasia

20.0

Protein p53/metabolism

20.0

Trans-Activators/genetics

20.0

Carcinoma, Renal Cell/*genetics/*metabolism/pathology

2100.0

Hippel-Lindau Disease

266.0

Ligases/deficiency/*genetics

360.0

Polymorphism, Single Nucleotide

20.0

Transcription Factors/genetics/metabolism

20.0

Hemangioblastoma/*etiology/physiopathology/*surgery

3100.0

Hippel-Lindau Disease/*complications/pathology/physiopathology

2100.0

*Outcome Assessment (Health Care)

36.0

Recovery of Function/physiology

327.0

Spinal Cord Neoplasms/*etiology/physiopathology/*surgery

2100.0

Carcinoma, Non-Small-Cell Lung/*genetics/pathology

27.0

Lung Neoplasms/*genetics/pathology

22.0

Arginine

22.0

Leucine

24.0