MeSH term
Frequency | Condition_Probility | Animals | 92 | 0.0 |
DNA-Binding Proteins/*metabolism | 26 | 1.0 |
Enzyme Activation/drug effects | 10 | 1.0 |
Interleukin-10/*pharmacology | 3 | 3.0 |
JNK Mitogen-Activated Protein Kinases | 2 | 0.0 |
*Milk Proteins | 21 | 4.0 |
Mitogen-Activated Protein Kinases/*metabolism | 2 | 0.0 |
Phosphorylation | 83 | 1.0 |
Protein-Tyrosine Kinase/*metabolism | 59 | 7.0 |
Proteins/metabolism | 36 | 3.0 |
*Proto-Oncogene Proteins | 59 | 3.0 |
Rats | 11 | 0.0 |
Research Support, Non-U.S. Gov't | 143 | 0.0 |
Signal Transduction/drug effects | 10 | 1.0 |
Trans-Activators/*metabolism | 28 | 2.0 |
Tumor Cells, Cultured | 45 | 0.0 |
Active Transport, Cell Nucleus | 3 | 1.0 |
Cell Division/drug effects | 10 | 0.0 |
Cell Nucleus/metabolism | 9 | 0.0 |
Cells, Cultured | 32 | 0.0 |
DNA-Binding Proteins/metabolism | 29 | 1.0 |
Humans | 157 | 0.0 |
Kinetics | 10 | 0.0 |
Phosphoproteins/metabolism | 6 | 0.0 |
Phosphorylation/drug effects | 11 | 1.0 |
Protein-Tyrosine Kinase/metabolism | 26 | 2.0 |
*Signal Transduction | 25 | 1.0 |
Trans-Activators/metabolism | 34 | 3.0 |
Amino Acid Sequence | 37 | 0.0 |
Dimerization | 3 | 0.0 |
Mice | 52 | 0.0 |
Mice, Inbred BALB C | 6 | 0.0 |
Molecular Sequence Data | 51 | 0.0 |
Female | 7 | 0.0 |
Interleukin-12/*pharmacology | 6 | 12.0 |
Ligands | 5 | 0.0 |
Up-Regulation | 5 | 0.0 |
Apoptosis/drug effects | 3 | 0.0 |
Blotting, Western | 8 | 0.0 |
Down-Regulation | 2 | 0.0 |
Interleukin-6/*pharmacology | 3 | 1.0 |
*Intracellular Signaling Peptides and Proteins | 7 | 0.0 |
Protein Transport | 2 | 0.0 |
*Repressor Proteins | 6 | 0.0 |
Transforming Growth Factor beta/*pharmacology | 3 | 0.0 |
Tyrosine/metabolism | 28 | 2.0 |
Cell Line | 50 | 0.0 |
DNA-Binding Proteins/genetics/*metabolism | 4 | 0.0 |
Interferon-alpha/metabolism | 5 | 22.0 |
Interferon-beta/metabolism | 3 | 15.0 |
Signal Transduction | 48 | 0.0 |
Trans-Activators/genetics/*metabolism | 4 | 1.0 |
Gene Expression Regulation/drug effects | 7 | 0.0 |
Interleukin-12/pharmacology/*physiology | 2 | 40.0 |
Mice, Knockout | 12 | 0.0 |
*Protein-Tyrosine Kinase | 12 | 3.0 |
Receptors, Interleukin/metabolism | 7 | 12.0 |
Signal Transduction/*drug effects | 11 | 3.0 |
Mitogen-Activated Protein Kinase 1/metabolism | 7 | 1.0 |
Mitogen-Activated Protein Kinase 3 | 6 | 0.0 |
Mitogen-Activated Protein Kinases/metabolism | 5 | 0.0 |
Protein-Tyrosine-Phosphatase/metabolism | 4 | 3.0 |
Receptors, Interferon/metabolism | 5 | 12.0 |
Signal Transduction/*physiology | 15 | 1.0 |
3T3 Cells | 7 | 0.0 |
Cell Differentiation | 4 | 0.0 |
Cell Separation | 2 | 0.0 |
Dose-Response Relationship, Drug | 4 | 0.0 |
Enzyme Inhibitors/pharmacology | 7 | 0.0 |
Epidermal Growth Factor/pharmacology | 3 | 0.0 |
Immunoblotting | 7 | 0.0 |
Jurkat Cells | 4 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 59 | 0.0 |
Time Factors | 6 | 0.0 |
Antigens, CD/*metabolism | 2 | 0.0 |
Cell Survival/drug effects | 3 | 0.0 |
Enzyme Activation | 30 | 0.0 |
Microscopy, Fluorescence | 2 | 0.0 |
Tumor Necrosis Factor-alpha/*pharmacology | 2 | 0.0 |
COS Cells | 12 | 0.0 |
Hela Cells | 11 | 0.0 |
Receptors, Cytokine/*metabolism | 2 | 2.0 |
Proteins/chemistry/metabolism | 2 | 6.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 5 | 0.0 |
Sequence Homology, Amino Acid | 14 | 0.0 |
Comparative Study | 12 | 0.0 |
DNA-Binding Proteins/*biosynthesis/genetics | 2 | 2.0 |
Interferon-beta/pharmacology | 5 | 11.0 |
Protein Biosynthesis | 7 | 0.0 |
Proteins/genetics | 4 | 0.0 |
RNA, Messenger/biosynthesis | 3 | 0.0 |
*Ubiquitin-Protein Ligases | 2 | 0.0 |
Protein-Tyrosine Kinase/chemistry/*metabolism | 2 | 5.0 |
Protein-Tyrosine-Phosphatase/*metabolism | 4 | 3.0 |
Proteins/chemistry/*metabolism | 2 | 2.0 |
Substrate Specificity | 2 | 0.0 |
Cell Survival | 3 | 0.0 |
Flow Cytometry | 6 | 0.0 |
Luciferases/metabolism | 2 | 0.0 |
Plasmids/metabolism | 2 | 0.0 |
Precipitin Tests | 6 | 0.0 |
Protein Binding | 10 | 0.0 |
Protein Structure, Tertiary | 3 | 0.0 |
Proteins/*metabolism | 19 | 2.0 |
Reverse Transcriptase Polymerase Chain Reaction | 7 | 0.0 |
Transcription, Genetic | 4 | 0.0 |
Transfection | 36 | 0.0 |
MAP Kinase Kinase 1 | 2 | 1.0 |
Phosphoproteins/*metabolism | 5 | 1.0 |
Cell Line, Tumor | 2 | 0.0 |
Interferon-alpha/*pharmacology | 8 | 5.0 |
Phosphotyrosine/metabolism | 7 | 1.0 |
Adult | 4 | 0.0 |
Aged | 3 | 0.0 |
DNA-Binding Proteins/analysis | 2 | 2.0 |
Male | 8 | 0.0 |
Middle Aged | 4 | 0.0 |
Protein-Tyrosine Kinase/*analysis | 2 | 6.0 |
Amino Acid Motifs | 2 | 0.0 |
Cell Membrane/metabolism | 4 | 0.0 |
Cell Nucleus/*metabolism | 2 | 0.0 |
Interferon-alpha/pharmacology | 5 | 5.0 |
Cercopithecus aethiops | 2 | 0.0 |
Signal Transduction/*drug effects/physiology | 2 | 3.0 |
Virus Replication | 2 | 0.0 |
DNA-Binding Proteins/*antagonists & inhibitors/metabolism | 2 | 6.0 |
Gene Expression Regulation | 7 | 0.0 |
Hamsters | 2 | 0.0 |
Trans-Activators/*antagonists & inhibitors/metabolism | 2 | 10.0 |
DNA, Complementary/genetics | 4 | 0.0 |
Protein-Tyrosine Kinase/*genetics | 5 | 2.0 |
Disease Progression | 2 | 0.0 |
Gene Expression | 5 | 0.0 |
RNA, Messenger/analysis | 5 | 0.0 |
Monocytes/metabolism | 2 | 0.0 |
Trans-Activation (Genetics) | 2 | 0.0 |
Cytokines/*metabolism | 2 | 0.0 |
Gene Expression Regulation, Neoplastic/drug effects/physiology | 2 | 5.0 |
Interferon Type II/pharmacology | 3 | 0.0 |
Interferon-alpha/*metabolism | 7 | 30.0 |
Mutation | 8 | 0.0 |
Ribonucleases/metabolism | 2 | 1.0 |
Interleukin-13/*pharmacology | 4 | 8.0 |
Interleukin-4/*pharmacology | 7 | 3.0 |
Mice, Inbred C57BL | 5 | 0.0 |
Blotting, Northern | 7 | 0.0 |
Cloning, Molecular | 9 | 0.0 |
Fibroblasts/metabolism | 2 | 0.0 |
Glutathione Transferase/metabolism | 2 | 0.0 |
Microscopy, Confocal | 2 | 0.0 |
RNA, Messenger/metabolism | 4 | 0.0 |
Tissue Distribution | 2 | 0.0 |
Antibodies, Monoclonal/immunology | 2 | 0.0 |
Antiviral Agents/*pharmacology | 2 | 1.0 |
Cell Division | 9 | 0.0 |
Killer Cells, Natural/immunology | 2 | 0.0 |
Phosphotyrosine | 11 | 4.0 |
Transcription Factors/metabolism | 8 | 0.0 |
Cattle | 2 | 0.0 |
Lymphokines/*pharmacology | 2 | 0.0 |
Receptor Protein-Tyrosine Kinases/metabolism | 3 | 1.0 |
Antigens, CD/metabolism | 7 | 0.0 |
Cell Division/drug effects/physiology | 2 | 0.0 |
Membrane Glycoproteins/metabolism | 5 | 0.0 |
Peptides/*pharmacology | 5 | 2.0 |
Base Sequence | 29 | 0.0 |
Exons | 3 | 0.0 |
Introns | 3 | 0.0 |
Phylogeny | 2 | 0.0 |
Recombinant Fusion Proteins/genetics/metabolism | 2 | 0.0 |
Regulatory Sequences, Nucleic Acid | 2 | 0.0 |
Sequence Alignment | 8 | 0.0 |
Animals, Newborn | 3 | 0.0 |
Coculture Techniques | 2 | 0.0 |
In Vitro | 3 | 0.0 |
Models, Biological | 3 | 0.0 |
Immunohistochemistry | 4 | 0.0 |
Depression, Chemical | 2 | 1.0 |
Protein-Tyrosine Kinase/*antagonists & inhibitors | 3 | 1.0 |
DNA, Complementary | 4 | 0.0 |
Point Mutation | 3 | 0.0 |
Proteins/genetics/*metabolism | 7 | 1.0 |
Cell Line, Transformed | 5 | 0.0 |
Membrane Glycoproteins/*metabolism | 2 | 0.0 |
Recombinant Proteins/pharmacology | 9 | 0.0 |
DNA/metabolism | 3 | 0.0 |
DNA-Binding Proteins/*physiology | 4 | 0.0 |
Mutagenesis, Site-Directed | 7 | 0.0 |
Promoter Regions (Genetics) | 4 | 0.0 |
Protein-Tyrosine Kinase/*physiology | 6 | 4.0 |
Trans-Activators/*physiology | 6 | 2.0 |
*Transcription, Genetic | 3 | 0.0 |
Receptors, Cell Surface/*metabolism | 2 | 0.0 |
Receptors, Interferon/*metabolism | 3 | 10.0 |
Serine/metabolism | 2 | 0.0 |
Protein-Serine-Threonine Kinases/metabolism | 2 | 0.0 |
*Cell Cycle Proteins | 2 | 0.0 |
Cytoplasm/metabolism | 3 | 0.0 |
Multiple Myeloma | 2 | 10.0 |
Proto-Oncogene Proteins/*metabolism | 4 | 0.0 |
*Saccharomyces cerevisiae Proteins | 2 | 0.0 |
DNA-Binding Proteins/analysis/metabolism | 2 | 9.0 |
Proteins/analysis/metabolism | 2 | 33.0 |
Trans-Activators/analysis/metabolism | 2 | 50.0 |
Binding Sites | 12 | 0.0 |
Lymphocyte Activation/drug effects | 2 | 0.0 |
src Homology Domains | 7 | 1.0 |
Cytoskeleton/*metabolism | 2 | 1.0 |
Prostatic Neoplasms/*enzymology | 2 | 4.0 |
Cell Division/physiology | 2 | 0.0 |
Protein-Tyrosine Kinase/chemistry/metabolism | 2 | 12.0 |
Receptors, Cytokine/metabolism | 3 | 3.0 |
Signal Transduction/physiology | 5 | 0.0 |
Neoplasm Proteins/*metabolism | 3 | 0.0 |
Protein-Tyrosine Kinase/analysis/*metabolism | 2 | 28.0 |
Signal Transduction/*genetics | 4 | 3.0 |
Chromosome Mapping | 4 | 0.0 |
Polymerase Chain Reaction | 3 | 0.0 |
RNA, Messenger/genetics | 3 | 0.0 |
Interferons/pharmacology | 3 | 4.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism | 3 | 0.0 |
Mitogen-Activated Protein Kinase 1 | 2 | 1.0 |
*Mitogen-Activated Protein Kinases | 3 | 0.0 |
Rats, Wistar | 3 | 0.0 |
Transcription Factors/biosynthesis | 2 | 2.0 |
Cytokines/physiology | 3 | 1.0 |
Molecular Structure | 2 | 0.0 |
Gene Expression Regulation, Enzymologic | 2 | 0.0 |
Tetradecanoylphorbol Acetate/pharmacology | 2 | 0.0 |
DNA Primers | 4 | 0.0 |
Thrombopoietin/*metabolism | 2 | 7.0 |
Sequence Deletion | 8 | 0.0 |
Protein Kinases/*metabolism | 2 | 0.0 |
Protein-Tyrosine Kinase/physiology | 2 | 1.0 |
Trans-Activators/metabolism/*physiology | 2 | 3.0 |
Urinary Plasminogen Activator/*pharmacology | 2 | 25.0 |
Catalysis | 3 | 0.0 |
DNA | 3 | 0.0 |
Protein-Tyrosine Kinase/genetics/*metabolism | 3 | 2.0 |
Interleukin-13/pharmacology/*physiology | 2 | 28.0 |
Enzyme Activation/physiology | 2 | 1.0 |
Hydrogen Peroxide/pharmacology | 2 | 0.0 |
Protein-Tyrosine Kinase/metabolism/*physiology | 3 | 11.0 |
Signal Transduction/drug effects/*physiology | 3 | 1.0 |
Interleukin-2/pharmacology | 2 | 0.0 |
Lymphocyte Activation/*drug effects | 2 | 0.0 |
Enzyme Induction | 2 | 0.0 |
Interleukin-13/*pharmacology/physiology | 2 | 40.0 |
Chimeric Proteins/chemistry/metabolism | 2 | 3.0 |
Receptors, Interferon/chemistry/genetics/*metabolism | 2 | 25.0 |
Structure-Activity Relationship | 5 | 0.0 |
Mammals | 2 | 0.0 |
Fibroblasts | 2 | 0.0 |
Enzyme Inhibitors | 2 | 2.0 |
Interferon Type II/*pharmacology | 4 | 0.0 |
Protein-Tyrosine Kinase/antagonists & inhibitors/metabolism | 2 | 3.0 |
Cytokines/chemistry/*physiology | 2 | 33.0 |
Models, Molecular | 2 | 0.0 |
Protein Conformation | 3 | 0.0 |
Receptors, Cytokine/chemistry/*physiology | 2 | 50.0 |
Rabbits | 3 | 0.0 |
Sequence Homology, Nucleic Acid | 3 | 0.0 |
Lymphocyte Activation/*physiology | 2 | 2.0 |
Macromolecular Substances | 8 | 0.0 |
Proteins/*physiology | 3 | 1.0 |
Fibrosarcoma | 3 | 6.0 |
Interleukin-2/*pharmacology | 3 | 1.0 |
Interleukin-9/*pharmacology | 2 | 25.0 |
*Mutation | 3 | 0.0 |
Recombinant Fusion Proteins/metabolism | 6 | 0.0 |
Membrane Proteins/metabolism | 3 | 0.0 |
Receptor, Epidermal Growth Factor/metabolism | 2 | 0.0 |
Receptor, IGF Type 1/metabolism | 2 | 6.0 |
Aorta | 2 | 1.0 |
Forskolin/pharmacology | 2 | 0.0 |
Recombinant Proteins/metabolism | 2 | 0.0 |
Angiotensin II/*physiology | 3 | 8.0 |
Interferons/*pharmacology | 2 | 2.0 |
Granulocyte Colony-Stimulating Factor/*pharmacology | 2 | 1.0 |
Interferon-gamma, Recombinant/pharmacology | 3 | 1.0 |
Interleukin-3/pharmacology | 2 | 0.0 |
Interferon-beta/*pharmacology | 6 | 10.0 |
Cell Differentiation/physiology | 2 | 0.0 |
Receptors, Interferon/chemistry/genetics/*physiology | 2 | 100.0 |
Calpain/metabolism | 2 | 8.0 |
Platelet Aggregation | 2 | 1.0 |
Protein Processing, Post-Translational/*drug effects | 4 | 7.0 |
Thrombin/*pharmacology | 2 | 1.0 |
Thrombopoietin/*pharmacology | 3 | 3.0 |
Receptor, Epidermal Growth Factor/genetics/metabolism | 2 | 3.0 |
Receptors, Interleukin-4 | 5 | 7.0 |
Tumor Cells, Cultured/drug effects | 3 | 0.0 |
Cell Transformation, Viral | 3 | 1.0 |
*Adaptor Proteins, Signal Transducing | 3 | 0.0 |
Thymidine/metabolism | 2 | 0.0 |
Models, Structural | 2 | 1.0 |
*Neoplasm Proteins | 3 | 0.0 |
Molecular Weight | 2 | 0.0 |
*Protein Biosynthesis | 2 | 0.0 |
Antibodies | 3 | 0.0 |
Spodoptera | 2 | 0.0 |
Cytokines/pharmacology | 2 | 0.0 |
Mice, Nude | 2 | 0.0 |
Neoplasm Transplantation | 2 | 0.0 |
Phenotype | 2 | 0.0 |
*Cell Transformation, Neoplastic | 2 | 0.0 |
Oligodeoxyribonucleotides | 3 | 0.0 |
Antibodies, Monoclonal | 3 | 0.0 |
Gene Expression/drug effects | 2 | 0.0 |
Protein-Tyrosine Kinase/*biosynthesis | 3 | 12.0 |
Receptor, Epidermal Growth Factor/*metabolism | 2 | 0.0 |
T-Lymphocytes/*metabolism | 2 | 0.0 |
Transcription Factors/*metabolism | 2 | 0.0 |
Tyrosine/*metabolism | 2 | 0.0 |
Tyrosine/analogs & derivatives/metabolism | 4 | 3.0 |
Tyrosine/analogs & derivatives/analysis/metabolism | 3 | 27.0 |
Mutagenesis | 5 | 0.0 |
Genetic Complementation Test | 2 | 0.0 |
Interferon Type I, Recombinant/*pharmacology | 2 | 4.0 |
DNA/genetics/metabolism | 2 | 0.0 |
Receptors, Cytokine/*physiology | 2 | 7.0 |
*Gene Expression Regulation | 2 | 0.0 |
CD4-Positive T-Lymphocytes/immunology | 2 | 0.0 |
Proteins/genetics/*immunology | 2 | 25.0 |
Cell Transformation, Neoplastic | 2 | 0.0 |
Gene Library | 2 | 0.0 |
Proteins/genetics/*physiology | 2 | 1.0 |
Tyrphostins/pharmacology | 2 | 1.0 |
Protein Processing, Post-Translational | 2 | 0.0 |
Recombinant Fusion Proteins/pharmacology | 2 | 2.0 |