MeSH term
Frequency | Condition_Probility | Animals | 79 | 0.0 |
Blotting, Western | 11 | 0.0 |
Cells, Cultured | 18 | 0.0 |
Cycloheximide/pharmacology | 2 | 0.0 |
Humans | 141 | 0.0 |
Mice | 47 | 0.0 |
Protein Synthesis Inhibitors/pharmacology | 2 | 0.0 |
Rats | 6 | 0.0 |
Research Support, Non-U.S. Gov't | 103 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 59 | 0.0 |
Signal Transduction/*immunology | 3 | 0.0 |
Amino Acid Sequence | 41 | 0.0 |
Base Sequence | 8 | 0.0 |
Cloning, Molecular | 13 | 0.0 |
DNA Primers | 6 | 0.0 |
Electrophoretic Mobility Shift Assay | 3 | 0.0 |
Enzyme Activation | 28 | 0.0 |
Interleukin-1/*physiology | 6 | 6.0 |
Molecular Sequence Data | 39 | 0.0 |
Protein-Serine-Threonine Kinases/metabolism | 11 | 1.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 11 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 7 | 0.0 |
Tumor Necrosis Factor-alpha/*physiology | 2 | 0.0 |
Cell Line | 62 | 0.0 |
Cytoplasm/metabolism | 3 | 0.0 |
Immunohistochemistry | 2 | 0.0 |
Mice, Knockout | 3 | 0.0 |
Phenotype | 3 | 0.0 |
Protein Binding | 27 | 0.0 |
Receptors, Tumor Necrosis Factor/physiology | 2 | 2.0 |
TNF Receptor-Associated Factor 6 | 96 | 75.0 |
Antigens, Differentiation/metabolism | 7 | 5.0 |
Kidney | 3 | 0.0 |
Kinetics | 4 | 0.0 |
NF-kappa B/*metabolism | 33 | 5.0 |
PC12 Cells | 3 | 0.0 |
Receptors, Immunologic/metabolism | 6 | 3.0 |
Receptors, Interleukin-1/*physiology | 4 | 28.0 |
CD40 Ligand/metabolism | 2 | 8.0 |
Cell Compartmentation | 2 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 2 | 0.0 |
Flow Cytometry | 5 | 0.0 |
Immunoblotting | 5 | 0.0 |
Macromolecular Substances | 5 | 0.0 |
Mitogen-Activated Protein Kinases/*metabolism | 6 | 1.0 |
Protein Transport/physiology | 2 | 1.0 |
Proteins/*metabolism | 26 | 2.0 |
RNA, Messenger/biosynthesis | 2 | 0.0 |
Signal Transduction/physiology | 8 | 0.0 |
DNA, Complementary/metabolism | 3 | 0.0 |
*Drosophila Proteins | 10 | 0.0 |
Genes, Reporter | 11 | 0.0 |
Interleukin-1/metabolism | 8 | 3.0 |
*JNK Mitogen-Activated Protein Kinases | 3 | 3.0 |
MAP Kinase Signaling System | 4 | 1.0 |
Mitogen-Activated Protein Kinase Kinases/metabolism | 6 | 3.0 |
Mitogen-Activated Protein Kinases/metabolism | 10 | 0.0 |
Multigene Family | 2 | 0.0 |
NF-kappa B/metabolism | 32 | 4.0 |
Phosphorylation | 14 | 0.0 |
Precipitin Tests | 14 | 0.0 |
Proteins/metabolism | 23 | 2.0 |
Receptors, Interleukin-1/metabolism | 7 | 30.0 |
Recombinant Proteins/metabolism | 12 | 0.0 |
Signal Transduction | 34 | 0.0 |
Time Factors | 8 | 0.0 |
Tissue Distribution | 2 | 0.0 |
DNA-Binding Proteins/*metabolism | 4 | 0.0 |
Protein Kinases/metabolism | 13 | 3.0 |
Receptors, Cell Surface/*metabolism | 9 | 1.0 |
*Signal Transduction | 25 | 1.0 |
Species Specificity | 2 | 0.0 |
Membrane Glycoproteins/*metabolism | 9 | 1.0 |
Receptors, Interleukin-1/*metabolism | 8 | 29.0 |
Signal Transduction/*physiology | 14 | 1.0 |
Antigens, Differentiation/*physiology | 3 | 3.0 |
Membrane Glycoproteins/*physiology | 5 | 1.0 |
Mice, Inbred C57BL | 5 | 0.0 |
Proteins/*physiology | 8 | 4.0 |
Receptors, Cell Surface/*physiology | 5 | 2.0 |
Receptors, Immunologic/*physiology | 2 | 1.0 |
Ubiquitin/metabolism | 3 | 1.0 |
*Adaptor Proteins, Signal Transducing | 16 | 1.0 |
Carrier Proteins/*metabolism | 11 | 1.0 |
Glycoproteins/*metabolism | 3 | 1.0 |
Ligands | 5 | 0.0 |
MAP Kinase Kinase Kinases/*metabolism | 7 | 20.0 |
MAP Kinase Signaling System/*physiology | 2 | 2.0 |
Macrophages/metabolism | 3 | 0.0 |
Receptors, Cytoplasmic and Nuclear/*metabolism | 3 | 2.0 |
Receptors, Tumor Necrosis Factor/metabolism | 9 | 4.0 |
Transfection | 34 | 0.0 |
Cell Differentiation | 4 | 0.0 |
Gene Library | 2 | 0.0 |
Glutathione Transferase/metabolism | 3 | 0.0 |
JNK Mitogen-Activated Protein Kinases | 23 | 4.0 |
Luciferases/metabolism | 5 | 0.0 |
Membrane Glycoproteins/metabolism | 3 | 0.0 |
Microscopy, Confocal | 2 | 0.0 |
Protein Structure, Tertiary | 11 | 0.0 |
Proteins/metabolism/*physiology | 3 | 6.0 |
Recombinant Fusion Proteins/metabolism | 7 | 0.0 |
*Transcription Factors | 3 | 0.0 |
Two-Hybrid System Techniques | 8 | 0.0 |
*Zinc Fingers | 2 | 0.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism | 9 | 2.0 |
Down-Regulation | 4 | 0.0 |
Enzyme Inhibitors/pharmacology | 5 | 0.0 |
Genes, Dominant | 2 | 0.0 |
Hela Cells | 9 | 0.0 |
Interleukin-1/*metabolism | 8 | 10.0 |
MAP Kinase Kinase 3 | 2 | 10.0 |
MAP Kinase Kinase 6 | 4 | 13.0 |
Protein Kinases/*metabolism | 6 | 1.0 |
Protein-Tyrosine Kinase/metabolism | 4 | 0.0 |
*Saccharomyces cerevisiae Proteins | 2 | 0.0 |
Transcription Factors/metabolism | 2 | 0.0 |
Tumor Cells, Cultured | 13 | 0.0 |
p38 Mitogen-Activated Protein Kinases | 10 | 1.0 |
Antigens, Differentiation/genetics/metabolism | 2 | 15.0 |
Gene Expression Regulation/immunology | 3 | 1.0 |
MAP Kinase Kinase Kinases/metabolism | 4 | 12.0 |
*Membrane Glycoproteins | 5 | 0.0 |
Membrane Proteins/*metabolism | 3 | 0.0 |
NF-kappa B/genetics/*metabolism | 4 | 5.0 |
*Receptors, Cell Surface | 2 | 0.0 |
Receptors, Immunologic/*metabolism | 3 | 1.0 |
Signal Transduction/immunology | 2 | 0.0 |
Amino Acid Motifs | 6 | 0.0 |
TNF Receptor-Associated Factor 1 | 14 | 9.0 |
TNF Receptor-Associated Factor 2 | 33 | 16.0 |
TNF Receptor-Associated Factor 3 | 12 | 17.0 |
TNF Receptor-Associated Factor 5 | 11 | 33.0 |
Carrier Proteins/*physiology | 5 | 2.0 |
Herpesvirus 4, Human/physiology | 2 | 6.0 |
Membrane Proteins/metabolism | 3 | 0.0 |
Microscopy, Fluorescence | 3 | 0.0 |
Mitogen-Activated Protein Kinase 8 | 2 | 2.0 |
Models, Biological | 7 | 0.0 |
Proteins/genetics/*physiology | 5 | 3.0 |
Structure-Activity Relationship | 3 | 0.0 |
Binding Sites | 17 | 0.0 |
Dimerization | 5 | 0.0 |
Mutation | 10 | 0.0 |
Biological Transport | 3 | 0.0 |
Cell Membrane/metabolism | 4 | 0.0 |
Cytosol/metabolism | 4 | 0.0 |
Interleukin-1/*pharmacology | 7 | 1.0 |
Carrier Proteins/genetics/*metabolism | 4 | 0.0 |
*Intracellular Signaling Peptides and Proteins | 11 | 1.0 |
Proteins/genetics/metabolism | 5 | 2.0 |
Sequence Alignment | 6 | 0.0 |
Tumor Necrosis Factor-alpha/metabolism | 2 | 0.0 |
Zinc Fingers | 5 | 0.0 |
Adaptor Proteins, Vesicular Transport/genetics/*metabolism | 2 | 40.0 |
Membrane Glycoproteins/genetics/*metabolism | 3 | 1.0 |
Proteins/genetics/*metabolism | 9 | 1.0 |
Bacterial Proteins/*metabolism | 2 | 4.0 |
Cell Line, Transformed | 4 | 0.0 |
*Gene Expression Regulation | 6 | 0.0 |
Membrane Glycoproteins/*immunology | 2 | 1.0 |
Tumor Necrosis Factor-alpha/pharmacology | 3 | 0.0 |
Virus Replication | 2 | 0.0 |
Crystallography, X-Ray | 2 | 0.0 |
Models, Molecular | 5 | 0.0 |
Protein Structure, Secondary | 2 | 0.0 |
Substrate Specificity | 2 | 0.0 |
Ubiquitin-Conjugating Enzymes | 2 | 4.0 |
Gene Expression Regulation | 4 | 0.0 |
Sequence Homology, Amino Acid | 14 | 0.0 |
Transcription, Genetic | 2 | 0.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/*metabolism | 6 | 2.0 |
Carrier Proteins/metabolism | 4 | 0.0 |
Multienzyme Complexes/metabolism | 2 | 1.0 |
Protein-Serine-Threonine Kinases/*metabolism | 7 | 1.0 |
Receptors, Tumor Necrosis Factor/*metabolism | 12 | 5.0 |
Signal Transduction/*drug effects | 4 | 1.0 |
Cell Survival | 3 | 0.0 |
Plasmids/metabolism | 4 | 0.0 |
*Protein-Serine-Threonine Kinases | 3 | 0.0 |
*Ubiquitin-Protein Ligases | 2 | 0.0 |
Proteins/physiology | 5 | 3.0 |
*Receptors, Immunologic | 6 | 3.0 |
Chromones/pharmacology | 2 | 0.0 |
Interleukin-8/genetics/metabolism | 2 | 9.0 |
Mitogen-Activated Protein Kinases/antagonists & inhibitors/*metabolism | 3 | 3.0 |
Morpholines/pharmacology | 2 | 0.0 |
Transcription Factor AP-1/genetics/*metabolism | 2 | 7.0 |
Jurkat Cells | 5 | 0.0 |
Peptide Mapping | 3 | 0.0 |
Promoter Regions (Genetics) | 3 | 0.0 |
Rabbits | 2 | 0.0 |
Capsid | 2 | 28.0 |
Lipopolysaccharides/pharmacology | 5 | 0.0 |
Plasmids | 3 | 0.0 |
Signal Transduction/drug effects | 3 | 0.0 |
Computational Biology | 2 | 1.0 |
Phylogeny | 2 | 0.0 |
Proteins/*genetics | 2 | 0.0 |
Proteins/chemistry/*metabolism | 2 | 2.0 |
Male | 4 | 0.0 |
Receptors, Tumor Necrosis Factor/*physiology | 4 | 4.0 |
Interleukin-8/*genetics | 2 | 7.0 |
Protein Kinases/*physiology | 2 | 3.0 |
Protein-Serine-Threonine Kinases/*physiology | 3 | 2.0 |
Protein Kinase C/*metabolism | 2 | 0.0 |
3T3 Cells | 3 | 0.0 |
Protein Kinases/genetics/*metabolism | 2 | 2.0 |
Tumor Necrosis Factor-alpha/*metabolism | 4 | 0.0 |
Interleukin-8/genetics | 2 | 3.0 |
Protein Biosynthesis | 3 | 0.0 |
*Sequence Homology, Amino Acid | 2 | 2.0 |
Receptors, Cell Surface/genetics/*metabolism | 2 | 1.0 |
DNA, Complementary/genetics | 4 | 0.0 |
*MAP Kinase Kinase Kinase 1 | 3 | 2.0 |
*Neoplasm Proteins | 2 | 0.0 |
Protein-Serine-Threonine Kinases/genetics/metabolism | 2 | 1.0 |
Proteins/chemistry/genetics/*metabolism | 4 | 4.0 |
Receptors, Tumor Necrosis Factor/*metabolism/physiology | 2 | 66.0 |
Protein-Serine-Threonine Kinases/physiology | 2 | 2.0 |
Apoptosis/*drug effects | 2 | 0.0 |
Comparative Study | 3 | 0.0 |
Caenorhabditis elegans | 2 | 2.0 |
RNA, Messenger/metabolism | 3 | 0.0 |
Antigens, CD40/*metabolism | 3 | 6.0 |
NF-kappa B/*antagonists & inhibitors/metabolism | 2 | 8.0 |
Tetradecanoylphorbol Acetate/metabolism | 2 | 6.0 |
Xenopus | 2 | 0.0 |
Mice, Inbred BALB C | 4 | 0.0 |
RNA Interference | 3 | 1.0 |
Enzyme Activation/immunology | 2 | 1.0 |
Up-Regulation/genetics/immunology | 2 | 3.0 |
Dose-Response Relationship, Drug | 4 | 0.0 |
Up-Regulation | 2 | 0.0 |
*Apoptosis | 3 | 0.0 |
Receptors, Nerve Growth Factor/*metabolism | 3 | 6.0 |
Antigens, CD40/metabolism | 2 | 3.0 |
Peptide Fragments/metabolism | 2 | 0.0 |
Peptide Fragments/chemistry/metabolism | 3 | 2.0 |
*Mitogen-Activated Protein Kinases | 10 | 2.0 |
Receptors, Tumor Necrosis Factor/genetics/*metabolism | 2 | 5.0 |
Interleukin-1/physiology | 2 | 2.0 |
Protein Binding/physiology | 2 | 0.0 |
Amino Acid Substitution | 4 | 0.0 |
Antigens, CD40/*physiology | 2 | 5.0 |
Mutagenesis, Site-Directed | 7 | 0.0 |
Proto-Oncogene Proteins/metabolism | 2 | 0.0 |
*Carrier Proteins | 3 | 0.0 |
Lipopolysaccharides/*pharmacology | 3 | 0.0 |
Antigens, CD40/chemistry/*physiology | 2 | 100.0 |
Sequence Deletion/genetics | 2 | 1.0 |
*Trans-Activation (Genetics) | 2 | 0.0 |
COS Cells | 2 | 0.0 |
Sequence Deletion | 2 | 0.0 |
Apoptosis | 4 | 0.0 |
Mammals | 2 | 0.0 |
Binding Sites/genetics | 3 | 0.0 |
Genetic Vectors | 3 | 0.0 |
Gene Deletion | 2 | 0.0 |
Child | 2 | 0.0 |
Cyclins/metabolism | 2 | 0.0 |
Gene Expression Profiling | 2 | 0.0 |
*Antigens, Differentiation | 2 | 2.0 |
Models, Immunological | 2 | 0.0 |
NF-kappa B/*metabolism/*physiology | 2 | 66.0 |
*Proteins | 3 | 0.0 |
Viral Matrix Proteins/*metabolism | 2 | 8.0 |
DNA, Complementary | 2 | 0.0 |
NF-kappa B/antagonists & inhibitors/metabolism | 2 | 6.0 |
Transcription Factors/*metabolism | 2 | 0.0 |
Protein Transport | 2 | 0.0 |
Cell Nucleus/metabolism | 2 | 0.0 |
Luciferases/genetics | 2 | 0.0 |
Carrier Proteins/chemistry/*physiology | 2 | 5.0 |
Cell Division | 2 | 0.0 |
Protein Conformation | 3 | 0.0 |
Proteins/chemistry/*physiology | 2 | 9.0 |
Receptors, Cell Surface/metabolism | 2 | 0.0 |
Female | 4 | 0.0 |
I-kappa B/metabolism | 2 | 2.0 |
Interleukin-1/pharmacology | 2 | 0.0 |
Ubiquitin/*metabolism | 2 | 1.0 |
NF-kappa B/antagonists & inhibitors/*metabolism | 3 | 5.0 |
Protein Structure, Tertiary/physiology | 2 | 1.0 |
Osteoclasts/*metabolism | 2 | 15.0 |
Receptors, Nerve Growth Factor/genetics/*metabolism | 2 | 12.0 |
Membrane Glycoproteins/*genetics | 2 | 0.0 |
Receptors, Cell Surface/*genetics | 2 | 0.0 |