MeSH term
Frequency | Condition_Probility | Humans | 223 | 0.0 |
3-Hydroxysteroid Dehydrogenases/biosynthesis/genetics | 2 | 50.0 |
Animals | 153 | 0.0 |
Cattle | 10 | 0.0 |
Cholesterol Side-Chain Cleavage Enzyme/biosynthesis/genetics | 2 | 100.0 |
Female | 101 | 0.0 |
Male | 57 | 0.0 |
Mice | 57 | 0.0 |
Phosphoproteins/biosynthesis/genetics | 2 | 11.0 |
Rats | 42 | 0.0 |
Steroid 17-alpha-Hydroxylase/biosynthesis/genetics | 2 | 100.0 |
Steroids/*biosynthesis | 26 | 46.0 |
Adenylate Cyclase/metabolism | 3 | 2.0 |
Cholesterol Side-Chain Cleavage Enzyme/metabolism | 7 | 63.0 |
Cyclic AMP/metabolism | 13 | 2.0 |
Digitoxin/pharmacology | 2 | 100.0 |
Digoxin/pharmacology | 2 | 66.0 |
Ouabain/pharmacology | 2 | 3.0 |
Phosphoproteins/metabolism | 13 | 2.0 |
Research Support, Non-U.S. Gov't | 141 | 0.0 |
Adult | 17 | 0.0 |
Chorionic Gonadotropin/pharmacology | 16 | 12.0 |
In Vitro | 8 | 0.0 |
Luteal Phase/physiology | 2 | 9.0 |
Phosphoproteins/genetics/metabolism | 5 | 6.0 |
RNA, Messenger/genetics/metabolism | 7 | 0.0 |
8-Bromo Cyclic Adenosine Monophosphate/pharmacology | 8 | 8.0 |
Cells, Cultured | 30 | 0.0 |
Granulosa Cells/drug effects/*metabolism | 3 | 13.0 |
Phosphoproteins/genetics | 16 | 13.0 |
Promoter Regions (Genetics)/drug effects/physiology | 2 | 6.0 |
RNA, Messenger/metabolism | 16 | 0.0 |
Recombinant Proteins/pharmacology | 5 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 111 | 0.0 |
Theca Cells/drug effects/*metabolism | 2 | 33.0 |
Corpus Luteum/cytology/*metabolism | 2 | 33.0 |
Progesterone/*metabolism | 3 | 8.0 |
Cholesterol/*metabolism | 21 | 8.0 |
Membrane Proteins/genetics/metabolism | 2 | 1.0 |
Mice, Knockout | 5 | 0.0 |
Mitochondria/metabolism | 21 | 8.0 |
*Mutation | 8 | 0.0 |
Phosphoproteins/*genetics/metabolism | 5 | 14.0 |
Steroids/biosynthesis | 18 | 52.0 |
Amino Acid Sequence | 37 | 0.0 |
Blotting, Northern | 15 | 0.0 |
*Carrier Proteins | 10 | 1.0 |
Cloning, Molecular | 12 | 0.0 |
In Situ Hybridization | 5 | 0.0 |
Kidney/metabolism | 3 | 0.0 |
Molecular Sequence Data | 54 | 0.0 |
Ovulation/physiology | 3 | 18.0 |
Phosphoproteins/*biosynthesis/*genetics | 2 | 66.0 |
RNA, Messenger/biosynthesis | 5 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 12 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 16 | 0.0 |
Tissue Distribution | 10 | 0.0 |
Corpus Luteum/*physiology | 2 | 20.0 |
*Fertilization in Vitro | 2 | 1.0 |
Granulosa Cells/*metabolism | 3 | 7.0 |
Phosphoproteins/*metabolism | 14 | 3.0 |
Progesterone/metabolism | 7 | 8.0 |
Base Sequence | 42 | 0.0 |
Carrier Proteins/*genetics/metabolism | 2 | 0.0 |
DNA, Complementary | 4 | 0.0 |
DNA-Binding Proteins/metabolism | 4 | 0.0 |
*Gene Expression Regulation | 8 | 0.0 |
*Membrane Transport Proteins | 2 | 0.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Sequence Homology, Amino Acid | 13 | 0.0 |
*Transcription Factors | 2 | 0.0 |
Cholesterol Side-Chain Cleavage Enzyme/genetics/metabolism | 4 | 50.0 |
Gene Expression | 12 | 0.0 |
Placenta/*metabolism | 2 | 1.0 |
Pregnancy | 9 | 0.0 |
MAP Kinase Signaling System | 2 | 0.0 |
Phosphorylation | 14 | 0.0 |
COS Cells | 20 | 0.0 |
Intracellular Membranes/metabolism | 7 | 3.0 |
Kinetics | 11 | 0.0 |
Mitochondria/*metabolism | 9 | 5.0 |
Phosphoproteins/chemistry/genetics/*metabolism | 2 | 4.0 |
Protein Binding | 9 | 0.0 |
*Receptors, Cell Surface | 2 | 0.0 |
Transfection | 29 | 0.0 |
Dose-Response Relationship, Drug | 18 | 0.0 |
Hydroxycholesterols/pharmacology | 3 | 10.0 |
Immunoblotting | 6 | 0.0 |
Pregnenolone/pharmacology | 2 | 66.0 |
Progesterone/*biosynthesis | 6 | 27.0 |
Radioimmunoassay | 5 | 0.0 |
Signal Transduction/drug effects | 3 | 0.0 |
Time Factors | 13 | 0.0 |
Tumor Cells, Cultured/drug effects | 2 | 0.0 |
Cholesterol/metabolism | 18 | 6.0 |
Gene Expression Regulation | 14 | 0.0 |
Granulosa Cells/metabolism | 6 | 17.0 |
Phosphoproteins/genetics/physiology | 2 | 14.0 |
Spectrum Analysis, Mass | 2 | 0.0 |
Structure-Activity Relationship | 12 | 0.0 |
Adolescent | 9 | 0.0 |
Age Factors | 3 | 0.0 |
Aged | 5 | 0.0 |
Codon | 2 | 0.0 |
Exons | 3 | 0.0 |
Homozygote | 3 | 0.0 |
Middle Aged | 5 | 0.0 |
Mutation | 12 | 0.0 |
Signal Transduction | 8 | 0.0 |
Adrenodoxin/metabolism | 2 | 40.0 |
Cell Division/drug effects | 2 | 0.0 |
Forskolin/pharmacology | 10 | 2.0 |
*Transfection | 2 | 0.0 |
Acetylation | 3 | 0.0 |
Biological Transport | 16 | 1.0 |
Comparative Study | 12 | 0.0 |
Histones/metabolism | 2 | 0.0 |
Lipids/metabolism | 3 | 0.0 |
Models, Biological | 11 | 0.0 |
Phenotype | 4 | 0.0 |
Promoter Regions (Genetics) | 12 | 0.0 |
Protein Processing, Post-Translational | 4 | 0.0 |
Protein Structure, Tertiary | 7 | 0.0 |
Recombinant Fusion Proteins/physiology | 2 | 0.0 |
Sequence Alignment | 9 | 0.0 |
Sequence Deletion | 4 | 0.0 |
Sequence Homology, Nucleic Acid | 5 | 0.0 |
Transcription, Genetic | 13 | 0.0 |
Blotting, Western | 15 | 0.0 |
Reference Values | 5 | 0.0 |
Interleukin-1/pharmacology | 2 | 0.0 |
Stromal Cells/*metabolism | 2 | 5.0 |
Cyclic AMP/physiology | 5 | 4.0 |
Phosphoproteins/*genetics | 46 | 19.0 |
*Transcription, Genetic | 5 | 0.0 |
Corpus Luteum/*metabolism | 3 | 16.0 |
Immunohistochemistry | 10 | 0.0 |
Phosphoproteins/*biosynthesis | 4 | 21.0 |
Carrier Proteins/metabolism | 3 | 0.0 |
Lysosomes/metabolism | 2 | 1.0 |
*Plant Proteins | 2 | 3.0 |
Brain/cytology/*metabolism | 2 | 4.0 |
Hormones/*biosynthesis | 4 | 44.0 |
Membrane Proteins/metabolism | 4 | 0.0 |
Phosphoproteins/*physiology | 7 | 8.0 |
Cell Line | 32 | 0.0 |
*DNA-Binding Proteins | 2 | 0.0 |
*Promoter Regions (Genetics)/drug effects | 3 | 7.0 |
Recombinant Proteins/genetics/metabolism | 3 | 0.0 |
Transcription Factors/genetics/metabolism | 2 | 0.0 |
Adrenal Cortex/cytology/drug effects/*physiology | 2 | 100.0 |
Phosphoproteins/genetics/*metabolism | 6 | 3.0 |
Progesterone/biosynthesis | 12 | 27.0 |
Aromatase/genetics | 3 | 21.0 |
Bone Morphogenetic Proteins/*pharmacology | 2 | 3.0 |
Cholesterol Side-Chain Cleavage Enzyme/genetics | 13 | 59.0 |
Estradiol/biosynthesis | 2 | 11.0 |
Follicle Stimulating Hormone/pharmacology | 2 | 3.0 |
Granulosa Cells/cytology/drug effects/metabolism | 2 | 100.0 |
RNA, Messenger/analysis | 11 | 0.0 |
Rats, Sprague-Dawley | 15 | 0.0 |
Polymorphism, Restriction Fragment Length | 2 | 0.0 |
Leydig Cell Tumor/*metabolism/pathology | 3 | 50.0 |
17-alpha-Hydroxyprogesterone/metabolism | 2 | 40.0 |
3-Hydroxysteroid Dehydrogenases/genetics | 3 | 50.0 |
Androgens/*biosynthesis | 6 | 37.0 |
Gene Expression Regulation, Enzymologic/*drug effects | 2 | 1.0 |
RNA, Messenger/genetics | 7 | 0.0 |
Steroid 17-alpha-Hydroxylase/genetics | 6 | 21.0 |
Child, Preschool | 3 | 0.0 |
Exons/genetics | 2 | 0.0 |
Infant | 9 | 0.0 |
Infant, Newborn | 5 | 0.0 |
Models, Molecular | 5 | 0.0 |
Pedigree | 4 | 0.0 |
Protein Conformation | 6 | 0.0 |
Cholesterol Side-Chain Cleavage Enzyme/*genetics | 4 | 20.0 |
Corticosterone/blood | 3 | 8.0 |
Heterozygote | 3 | 0.0 |
Introns | 2 | 0.0 |
Calcium Channel Blockers/pharmacology | 2 | 2.0 |
Leydig Cells/*drug effects/metabolism | 2 | 66.0 |
Binding Sites | 10 | 0.0 |
Recombinant Proteins/metabolism | 8 | 0.0 |
Tumor Cells, Cultured | 26 | 0.0 |
17-Hydroxysteroid Dehydrogenases/genetics | 2 | 33.0 |
Analysis of Variance | 4 | 0.0 |
Rats, Wistar | 3 | 0.0 |
Testosterone/*biosynthesis | 4 | 20.0 |
Gene Expression/drug effects | 5 | 0.0 |
Granulosa Cells/cytology/*metabolism | 2 | 66.0 |
Luteal Cells/cytology/*metabolism | 2 | 66.0 |
Cell Nucleus/metabolism | 2 | 0.0 |
Cyclic AMP-Dependent Protein Kinases/metabolism | 8 | 4.0 |
DNA Mutational Analysis | 2 | 0.0 |
Gene Expression Regulation/*physiology | 4 | 1.0 |
Aromatase/*genetics | 2 | 8.0 |
DNA-Binding Proteins/*genetics | 4 | 0.0 |
Leydig Cells/physiology | 2 | 15.0 |
Receptors, Retinoic Acid/*genetics | 3 | 5.0 |
*Repressor Proteins | 8 | 0.0 |
Transcription Factors/*genetics | 4 | 0.0 |
Up-Regulation | 4 | 0.0 |
DNA-Binding Proteins/pharmacology | 2 | 8.0 |
Promoter Regions (Genetics)/drug effects | 2 | 1.0 |
3-Hydroxysteroid Dehydrogenases/metabolism | 3 | 25.0 |
DNA Primers | 4 | 0.0 |
Steroid 17-alpha-Hydroxylase/genetics/metabolism | 2 | 28.0 |
*Gene Expression | 4 | 0.0 |
Hydroxycholesterols/metabolism | 4 | 23.0 |
Mitochondria/enzymology | 3 | 2.0 |
RNA/analysis | 2 | 0.0 |
DNA | 3 | 0.0 |
Polymerase Chain Reaction | 8 | 0.0 |
*Promoter Regions (Genetics) | 4 | 0.0 |
Enzyme Inhibitors/pharmacology | 8 | 0.0 |
Phosphoproteins/biosynthesis | 8 | 23.0 |
Pregnenolone/metabolism | 5 | 38.0 |
Adrenal Cortex Hormones/*biosynthesis | 2 | 28.0 |
Sex Reversal, Gonadal | 2 | 8.0 |
Chorionic Gonadotropin/metabolism | 2 | 6.0 |
Down-Regulation | 2 | 0.0 |
Enzyme Activation | 10 | 0.0 |
Flavonoids/pharmacology | 3 | 0.0 |
Microscopy, Fluorescence | 2 | 0.0 |
Plasmids/metabolism | 2 | 0.0 |
*Signal Transduction | 2 | 0.0 |
Ovary/*metabolism | 2 | 3.0 |
Steroid 17-alpha-Hydroxylase/*genetics | 3 | 9.0 |
Bucladesine/pharmacology | 6 | 3.0 |
Gene Expression Regulation/*drug effects | 11 | 1.0 |
Child | 7 | 0.0 |
Follicle Stimulating Hormone/blood | 2 | 0.0 |
Frameshift Mutation | 2 | 0.0 |
Promoter Regions (Genetics)/physiology | 3 | 1.0 |
Signal Transduction/physiology | 8 | 0.0 |
Cyclic AMP/*physiology | 2 | 2.0 |
Transcription, Genetic/*physiology | 3 | 1.0 |
Cytoplasm/metabolism | 3 | 0.0 |
Androstenedione/biosynthesis | 3 | 33.0 |
Cell Culture Techniques/methods | 2 | 0.0 |
Transforming Growth Factor beta/*pharmacology | 3 | 0.0 |
Calcium/metabolism | 2 | 0.0 |
*Proto-Oncogene Proteins | 2 | 0.0 |
Sheep | 2 | 0.0 |
Cercopithecus aethiops | 4 | 0.0 |
DNA-Binding Proteins/genetics/*metabolism | 4 | 0.0 |
Genes, Reporter | 5 | 0.0 |
Membrane Proteins/genetics | 2 | 0.0 |
Mutagenesis, Site-Directed | 9 | 0.0 |
Receptors, LDL/genetics | 2 | 2.0 |
Transcription Factors/metabolism | 3 | 0.0 |
Adrenal Hyperplasia, Congenital/genetics | 4 | 36.0 |
Intracellular Membranes/*metabolism | 4 | 6.0 |
Membrane Proteins/chemistry/metabolism | 2 | 6.0 |
Models, Chemical | 2 | 0.0 |
Phosphoproteins/deficiency/genetics/*metabolism | 2 | 50.0 |
Chorionic Gonadotropin/*pharmacology | 6 | 10.0 |
Hamsters | 10 | 0.0 |
Leydig Cell Tumor/*metabolism | 4 | 80.0 |
RNA, Messenger/*biosynthesis | 2 | 0.0 |
Testicular Neoplasms/*metabolism | 2 | 18.0 |
Cell Division | 4 | 0.0 |
Swine | 6 | 0.0 |
Membrane Proteins/chemistry/genetics/metabolism | 2 | 8.0 |
Organ Specificity | 5 | 0.0 |
Cell Separation | 2 | 0.0 |
Steroid 17-alpha-Hydroxylase/biosynthesis | 2 | 66.0 |
Steroids/analysis/biosynthesis | 2 | 100.0 |
Steroids/metabolism | 2 | 6.0 |
Trans-Activation (Genetics) | 2 | 0.0 |
Adrenal Cortex Neoplasms | 2 | 25.0 |
Cyclic AMP/pharmacology | 2 | 1.0 |
DNA-Binding Proteins/genetics/*physiology | 2 | 0.0 |
Transcription Factors/genetics/*physiology | 2 | 1.0 |
Cholesterol Side-Chain Cleavage Enzyme/*metabolism | 3 | 75.0 |
Pregnenolone/biosynthesis | 4 | 66.0 |
Gene Expression Regulation/drug effects | 5 | 0.0 |
Amino Acid Motifs | 2 | 0.0 |
Crystallography, X-Ray | 2 | 0.0 |
Solubility | 2 | 0.0 |
Substrate Specificity | 4 | 0.0 |
Disease Models, Animal | 3 | 0.0 |
Mice, Inbred BALB C | 3 | 0.0 |
Adenoma/*chemistry | 2 | 18.0 |
Gene Expression Regulation, Neoplastic | 2 | 0.0 |
Diagnosis, Differential | 2 | 0.0 |
Phosphoproteins/genetics/*physiology | 6 | 17.0 |
Cyclic AMP/*metabolism | 2 | 0.0 |
Phosphoproteins/*biosynthesis/genetics | 4 | 22.0 |
Adrenal Hyperplasia, Congenital/*genetics | 5 | 21.0 |
Alleles | 2 | 0.0 |
Sequence Analysis, DNA | 4 | 0.0 |
Base Sequence/genetics | 3 | 0.0 |
Gene Expression/physiology | 2 | 0.0 |
Potassium/pharmacology | 3 | 5.0 |
Computer Simulation | 2 | 0.0 |
DNA-Binding Proteins/*physiology | 3 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 3 | 0.0 |
Membrane Proteins/physiology | 2 | 2.0 |
Mitochondria/physiology | 2 | 3.0 |
Phosphoproteins/biosynthesis/*genetics | 4 | 28.0 |
Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology | 3 | 23.0 |
Dinoprost/*pharmacology | 2 | 28.0 |
Luciferases/genetics | 2 | 0.0 |
*Protein Folding | 2 | 1.0 |
DNA, Complementary/genetics | 4 | 0.0 |
Gene Expression Regulation, Neoplastic/drug effects | 2 | 0.0 |
Neoplasm Proteins/*genetics | 3 | 0.0 |
Tumor Cells, Cultured/drug effects/metabolism | 2 | 1.0 |
Lipids/*metabolism | 2 | 0.0 |
Japan | 2 | 0.0 |
Phylogeny | 2 | 0.0 |
Pilot Projects | 2 | 0.0 |
Calcimycin/pharmacology | 2 | 0.0 |
DNA-Binding Proteins/genetics | 2 | 0.0 |
Transcription Factors/genetics | 2 | 0.0 |
Cell Line, Tumor | 5 | 0.0 |
Electrophoretic Mobility Shift Assay | 2 | 0.0 |
Gene Expression Regulation, Enzymologic | 3 | 0.0 |
RNA, Messenger/*metabolism | 4 | 0.0 |
Adrenal Cortex/*metabolism | 3 | 18.0 |
Cytochrome P-450 Enzyme System/metabolism | 3 | 1.0 |
Pregnenolone/*biosynthesis | 3 | 100.0 |
Recombinant Proteins | 2 | 0.0 |
Adrenal Glands/pathology | 2 | 18.0 |
Drug Synergism | 3 | 0.0 |
Granulosa Cells/*drug effects/metabolism | 2 | 28.0 |
Receptors, Thyroid Hormone/*metabolism | 2 | 5.0 |
Cholera Toxin/pharmacology | 2 | 2.0 |
Cytochrome P-450 Enzyme System/genetics | 2 | 1.0 |
Testosterone/metabolism/secretion | 2 | 100.0 |
Gene Deletion | 3 | 0.0 |
Transcription Factors/*physiology | 3 | 0.0 |
Gene Frequency | 2 | 0.0 |
8-Bromo Cyclic Adenosine Monophosphate/metabolism | 2 | 20.0 |
Hela Cells | 2 | 0.0 |
Blotting, Southern | 2 | 0.0 |
Corticotropin/*pharmacology | 4 | 23.0 |
Aminoglutethimide/pharmacology | 2 | 28.0 |
Leydig Cells/*metabolism | 5 | 50.0 |
Stimulation, Chemical | 3 | 0.0 |
DNA Probes | 2 | 0.0 |
Urea/pharmacology | 2 | 5.0 |
Corticotropin/pharmacology | 3 | 5.0 |
Leydig Cells/drug effects/*metabolism | 2 | 28.0 |
RNA, Messenger/*analysis | 2 | 0.0 |
Phosphoproteins/*genetics/*metabolism | 2 | 14.0 |
Hypophysectomy | 2 | 3.0 |
Membrane Proteins/*genetics/metabolism | 2 | 1.0 |
Glutathione Transferase/metabolism | 2 | 0.0 |
Luciferases/metabolism | 2 | 0.0 |
Transcription Factors/genetics/*metabolism | 2 | 0.0 |
Mutation/*genetics | 2 | 0.0 |
Phosphoproteins/analysis/*genetics | 2 | 25.0 |
DNA-Binding Proteins/*metabolism | 2 | 0.0 |
Transcription Factors/*metabolism | 2 | 0.0 |
Fetus/metabolism | 2 | 1.0 |
Ovary/metabolism | 3 | 3.0 |
Rabbits | 2 | 0.0 |
Testis/metabolism | 2 | 0.0 |
Half-Life | 2 | 0.0 |
Protein Synthesis Inhibitors/pharmacology | 2 | 0.0 |
Sex Characteristics | 2 | 0.0 |
Testosterone/blood | 2 | 0.0 |
Chromosome Mapping | 3 | 0.0 |
Sequence Analysis | 2 | 0.0 |
Gonadotropins/*pharmacology | 3 | 17.0 |
Granulosa Cells/*drug effects/*metabolism | 2 | 50.0 |
Growth Substances/metabolism | 2 | 1.0 |
Cycloheximide/pharmacology | 2 | 0.0 |
Protein Biosynthesis | 3 | 0.0 |
Subcellular Fractions/enzymology | 2 | 2.0 |
Calcium Channel Agonists/pharmacology | 2 | 9.0 |
Adrenal Hyperplasia, Congenital/metabolism | 3 | 100.0 |
Oligonucleotide Probes/genetics | 2 | 1.0 |
Testis/*physiology | 2 | 5.0 |
Tetradecanoylphorbol Acetate/pharmacology | 3 | 0.0 |
Adrenal Hyperplasia, Congenital/*genetics/physiopathology | 2 | 100.0 |
English Abstract | 3 | 0.0 |
*Chromosomes, Human, Pair 13 | 2 | 1.0 |
Protein Kinase C/*antagonists & inhibitors | 2 | 6.0 |
Staurosporine | 2 | 2.0 |
Papio | 2 | 1.0 |
Metalloendopeptidases/*metabolism | 2 | 2.0 |
Protein Denaturation | 2 | 0.0 |
Genetic Vectors | 2 | 0.0 |
Cyclic GMP/metabolism | 2 | 2.0 |
*Gastrointestinal Hormones | 2 | 20.0 |
Two-Hybrid System Techniques | 2 | 0.0 |
Response Elements | 2 | 0.0 |
Gene Expression Profiling | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction/methods | 3 | 0.0 |
Steroid 11-beta-Hydroxylase/genetics | 2 | 11.0 |
Thermodynamics | 2 | 0.0 |
Testosterone/biosynthesis | 3 | 25.0 |