MeSH term
Frequency | Condition_Probility | Humans | 133 | 0.0 |
Immunohistochemistry | 10 | 0.0 |
Time Factors | 4 | 0.0 |
Adolescent | 10 | 0.0 |
Child | 11 | 0.0 |
Child, Preschool | 5 | 0.0 |
Genotype | 5 | 0.0 |
Infant | 5 | 0.0 |
Phenotype | 6 | 0.0 |
Proprotein Convertases | 3 | 6.0 |
Receptor, Melanocortin, Type 4 | 6 | 8.0 |
Receptors, Corticotropin/genetics | 2 | 16.0 |
Research Support, Non-U.S. Gov't | 91 | 0.0 |
Twin Studies | 2 | 11.0 |
Corticotropin/secretion | 8 | 13.0 |
Diagnosis, Differential | 2 | 0.0 |
Female | 53 | 0.0 |
Gene Expression Regulation | 4 | 0.0 |
Lung Neoplasms/secretion | 2 | 66.0 |
Male | 48 | 0.0 |
Paraneoplastic Endocrine Syndromes/*metabolism | 2 | 66.0 |
Animals | 76 | 0.0 |
Anti-Obesity Agents/chemistry/therapeutic use | 2 | 100.0 |
Body Weight/drug effects/*physiology | 2 | 100.0 |
Gene Expression | 7 | 0.0 |
MSH/genetics/*physiology | 3 | 100.0 |
Obesity/drug therapy/*physiopathology | 2 | 100.0 |
Receptors, Corticotropin/drug effects/genetics/physiology | 2 | 100.0 |
Receptors, Melanocortin | 8 | 8.0 |
Alleles | 3 | 0.0 |
Body Mass Index | 6 | 0.0 |
Exons | 4 | 0.0 |
Insulin/blood | 2 | 0.0 |
Leptin/*blood | 2 | 2.0 |
Middle Aged | 22 | 0.0 |
Mutation | 5 | 0.0 |
Obesity/*genetics | 8 | 6.0 |
Polymerase Chain Reaction | 10 | 0.0 |
*Polymorphism, Genetic | 3 | 0.0 |
Pro-Opiomelanocortin/*genetics | 38 | 90.0 |
Repetitive Sequences, Nucleic Acid | 3 | 0.0 |
English Abstract | 7 | 0.0 |
Leptin/physiology | 2 | 16.0 |
Life Style | 2 | 1.0 |
Genetic Predisposition to Disease | 2 | 0.0 |
Hypothalamus/*metabolism | 2 | 6.0 |
Pro-Opiomelanocortin/genetics/*metabolism | 4 | 100.0 |
Mice | 33 | 0.0 |
Obesity/genetics | 2 | 3.0 |
Signal Transduction | 4 | 0.0 |
Cells, Cultured | 8 | 0.0 |
Corticotropin/metabolism | 7 | 20.0 |
Gene Expression/*drug effects | 3 | 1.0 |
RNA, Messenger/metabolism | 5 | 0.0 |
Receptors, Pituitary Hormone/metabolism | 3 | 42.0 |
Reference Values | 5 | 0.0 |
Ultraviolet Rays | 4 | 0.0 |
alpha-MSH/metabolism | 2 | 13.0 |
Blotting, Western | 3 | 0.0 |
DNA/metabolism | 2 | 0.0 |
Genes, Reporter | 2 | 0.0 |
Melanocytes/metabolism | 2 | 5.0 |
Models, Biological | 3 | 0.0 |
Pro-Opiomelanocortin/*biosynthesis/genetics | 4 | 80.0 |
Promoter Regions (Genetics) | 3 | 0.0 |
Transcription Factors/*metabolism | 2 | 0.0 |
Transcription, Genetic | 5 | 0.0 |
Transfection | 11 | 0.0 |
Cell Line | 15 | 0.0 |
Cell-Free System | 2 | 0.0 |
Dose-Response Relationship, Drug | 3 | 0.0 |
Hela Cells | 2 | 0.0 |
Hydrogen-Ion Concentration | 2 | 0.0 |
In Vitro | 3 | 0.0 |
Kinetics | 7 | 0.0 |
Protein Binding | 3 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 5 | 0.0 |
Amino Acid Sequence | 18 | 0.0 |
Base Sequence | 23 | 0.0 |
Binding Sites | 3 | 0.0 |
Corticotropin/deficiency | 2 | 20.0 |
Mice, Transgenic | 3 | 0.0 |
Molecular Sequence Data | 25 | 0.0 |
Pituitary Neoplasms | 2 | 11.0 |
Sequence Alignment | 3 | 0.0 |
Sequence Homology, Amino Acid | 4 | 0.0 |
*Transcription, Genetic | 3 | 0.0 |
Tumor Cells, Cultured | 9 | 0.0 |
Adult | 27 | 0.0 |
Chromatography, High Pressure Liquid | 5 | 0.0 |
Corticotropin/*blood | 2 | 3.0 |
Pregnancy | 7 | 0.0 |
Pro-Opiomelanocortin/blood | 2 | 100.0 |
Pro-Opiomelanocortin/genetics | 7 | 38.0 |
Heterozygote | 3 | 0.0 |
Leptin | 3 | 2.0 |
Polymorphism, Single-Stranded Conformational | 3 | 0.0 |
DNA Primers | 2 | 0.0 |
Plasmids | 2 | 0.0 |
*Carrier Proteins | 2 | 0.0 |
*Cell Cycle Proteins | 2 | 0.0 |
*DNA Methylation | 2 | 0.0 |
*DNA-Binding Proteins | 2 | 0.0 |
Organ Specificity | 2 | 0.0 |
*Promoter Regions (Genetics) | 5 | 0.0 |
Sequence Analysis, DNA | 2 | 0.0 |
Chromosome Mapping | 7 | 0.0 |
*Chromosomes, Human, Pair 2 | 3 | 1.0 |
Cohort Studies | 3 | 0.0 |
Genetic Markers | 4 | 0.0 |
Leptin/blood | 3 | 5.0 |
Linkage (Genetics) | 2 | 0.0 |
*Mutation | 3 | 0.0 |
Polymorphism, Genetic | 3 | 0.0 |
Variation (Genetics) | 2 | 0.0 |
Pro-Opiomelanocortin/*metabolism | 7 | 77.0 |
Skin Pigmentation/*physiology | 2 | 33.0 |
Aged | 11 | 0.0 |
Aged, 80 and over | 4 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 45 | 0.0 |
Corticotropin/*secretion | 11 | 23.0 |
Cushing Syndrome/etiology | 2 | 66.0 |
Recombinant Proteins/pharmacology | 2 | 0.0 |
Transcription, Genetic/drug effects | 3 | 0.0 |
Eating/physiology | 2 | 3.0 |
Mice, Knockout | 5 | 0.0 |
Mutation/*genetics | 2 | 0.0 |
Corticotropin/blood | 4 | 2.0 |
Corticotropin-Releasing Hormone/blood | 2 | 12.0 |
Osmolar Concentration | 2 | 0.0 |
Pregnancy/*blood | 2 | 1.0 |
Blotting, Northern | 6 | 0.0 |
Pituitary Gland/metabolism | 4 | 7.0 |
*Proprotein Convertase 1 | 2 | 13.0 |
Rats | 18 | 0.0 |
Rats, Sprague-Dawley | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 6 | 0.0 |
Gene Expression Regulation/*physiology | 3 | 0.0 |
Histocytochemistry | 3 | 0.0 |
Case-Control Studies | 2 | 0.0 |
Hydrocortisone/blood | 2 | 0.0 |
Immunoradiometric Assay | 3 | 2.0 |
Placenta/*metabolism | 2 | 1.0 |
RNA, Messenger/analysis | 6 | 0.0 |
Cloning, Molecular | 4 | 0.0 |
DNA, Complementary | 3 | 0.0 |
Evolution | 3 | 0.0 |
Pituitary Gland/*enzymology | 2 | 33.0 |
Body Composition | 2 | 0.0 |
Fasting | 2 | 0.0 |
Energy Metabolism/*physiology | 2 | 2.0 |
Pro-Opiomelanocortin/biosynthesis/genetics | 2 | 66.0 |
Comparative Study | 16 | 0.0 |
Injections, Intraperitoneal | 2 | 1.0 |
Rats, Wistar | 4 | 0.0 |
Pro-Opiomelanocortin/metabolism | 5 | 55.0 |
Bronchial Neoplasms/metabolism | 3 | 60.0 |
Carcinoid Tumor/metabolism | 2 | 25.0 |
Receptors, Vasopressin/*genetics | 2 | 8.0 |
Adenoma/*chemistry/secretion | 2 | 66.0 |
Dexamethasone/diagnostic use | 2 | 5.0 |
Pituitary Function Tests | 2 | 6.0 |
Pituitary Neoplasms/*chemistry/secretion | 2 | 50.0 |
RNA, Messenger/*analysis | 6 | 1.0 |
Receptors, Glucocorticoid/*genetics | 2 | 7.0 |
Pituitary Gland/physiology | 2 | 7.0 |
Chromatography, Gel | 4 | 0.0 |
Endopeptidases/*metabolism | 2 | 1.0 |
Radioimmunoassay | 7 | 0.0 |
Body Weight/physiology | 2 | 2.0 |
Pro-Opiomelanocortin/*blood | 3 | 100.0 |
*Interleukin-6 | 4 | 1.0 |
Phosphorylation | 2 | 0.0 |
DNA Mutational Analysis | 2 | 0.0 |
Protein Precursors/*genetics | 6 | 4.0 |
Peptide Fragments/*pharmacology | 2 | 1.0 |
Prolactin/*secretion | 2 | 1.0 |
Analysis of Variance | 2 | 0.0 |
Corticotropin-Releasing Hormone/pharmacology | 4 | 11.0 |
DNA-Binding Proteins/*physiology | 2 | 0.0 |
Feedback | 2 | 1.0 |
Pro-Opiomelanocortin/genetics/metabolism | 5 | 71.0 |
Fetus | 2 | 0.0 |
Interleukin-6/pharmacology | 2 | 0.0 |
Peptides/pharmacology | 2 | 1.0 |
Chromosome Banding | 2 | 0.0 |
Adenoma/metabolism | 2 | 5.0 |
*Gene Expression | 3 | 0.0 |
Pituitary Neoplasms/metabolism | 2 | 12.0 |
Corticotropin/blood/*secretion | 2 | 8.0 |
Corticosterone/blood | 2 | 5.0 |
Recombination, Genetic | 2 | 0.0 |
Brain/metabolism | 3 | 0.0 |
Mice, Inbred C57BL | 6 | 0.0 |
RNA, Messenger/biosynthesis | 4 | 0.0 |
Restriction Mapping | 2 | 0.0 |
Species Specificity | 4 | 0.0 |
Corticotropin/biosynthesis/secretion | 2 | 100.0 |
Dexamethasone/pharmacology | 3 | 0.0 |
Pro-Opiomelanocortin/*biosynthesis | 4 | 80.0 |
Blotting, Southern | 2 | 0.0 |
Corticotropin/*deficiency | 2 | 11.0 |
Corticotropin-Releasing Hormone/*genetics | 3 | 33.0 |
ACTH Syndrome, Ectopic/*metabolism | 2 | 66.0 |
Stress/physiopathology | 2 | 8.0 |
Statistics, Nonparametric | 2 | 0.0 |
Protein Precursors/metabolism | 2 | 1.0 |
Spectrum Analysis, Mass | 2 | 0.0 |
Cattle | 4 | 0.0 |
Corticotropin/*analysis | 3 | 75.0 |
Cell Line, Transformed | 2 | 0.0 |
Pro-Opiomelanocortin/biosynthesis/*genetics | 3 | 100.0 |
Nucleic Acid Hybridization | 8 | 0.0 |
Corticotropin/blood/metabolism | 2 | 100.0 |
Pituitary Gland/*metabolism | 4 | 10.0 |
MSH/analysis | 2 | 28.0 |
Pro-Opiomelanocortin/*analysis | 3 | 100.0 |
DNA/analysis | 2 | 0.0 |
Protein Biosynthesis | 2 | 0.0 |
Hamsters | 3 | 0.0 |
Evolution, Molecular | 2 | 0.0 |
Phylogeny | 2 | 0.0 |
Proteins/*genetics | 2 | 0.0 |
Pituitary Gland/*chemistry | 2 | 28.0 |
Cushing Syndrome/*metabolism | 2 | 18.0 |
DNA/genetics | 2 | 0.0 |
Furin | 2 | 4.0 |
Sequence Homology, Nucleic Acid | 4 | 0.0 |
Gestational Age | 2 | 0.0 |
RNA, Messenger/*genetics | 2 | 0.0 |
Protein Processing, Post-Translational | 2 | 0.0 |
Mink/*genetics | 2 | 22.0 |
Swine | 2 | 0.0 |
Xenopus | 2 | 0.0 |
*Gene Expression Regulation | 2 | 0.0 |
Rats, Inbred Strains | 2 | 0.0 |
Peptide Fragments/*analysis | 3 | 6.0 |
Basal Metabolism | 2 | 4.0 |
Molecular Weight | 2 | 0.0 |
Protein Precursors/*metabolism | 2 | 2.0 |
Proteins/genetics | 2 | 0.0 |
*Genes, Structural | 4 | 0.0 |
Cricetulus | 2 | 0.0 |
DNA/*genetics | 2 | 0.0 |
*Cloning, Molecular | 2 | 0.0 |
Pituitary Gland/*analysis | 3 | 27.0 |
Tissue Distribution | 2 | 0.0 |
Hypothalamus/metabolism | 2 | 4.0 |
Receptors, Cell Surface/genetics | 2 | 1.0 |
Pituitary Hormones, Anterior/*genetics | 4 | 66.0 |
Pro-Opiomelanocortin | 7 | 77.0 |
Pituitary Gland/chemistry | 2 | 9.0 |
DNA Restriction Enzymes | 2 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 2 | 0.0 |
