MeSH term
Frequency | Condition_Probility | Chromatography, High Pressure Liquid | 3 | 0.0 |
Humans | 291 | 0.0 |
Sensitivity and Specificity | 8 | 0.0 |
Adolescent | 28 | 0.0 |
Adult | 79 | 0.0 |
Aged | 39 | 0.0 |
Female | 112 | 0.0 |
Genetic Markers/genetics | 7 | 1.0 |
Genetic Screening | 10 | 1.0 |
Genotype | 25 | 0.0 |
Haplotypes/genetics | 2 | 0.0 |
Heterozygote Detection | 2 | 0.0 |
Linkage (Genetics)/genetics | 11 | 4.0 |
Male | 107 | 0.0 |
Membrane Proteins/genetics | 15 | 4.0 |
Middle Aged | 62 | 0.0 |
Pedigree | 70 | 1.0 |
Polycystic Kidney, Autosomal Dominant/*complications/*genetics | 2 | 100.0 |
Proteins/genetics | 25 | 3.0 |
Research Support, Non-U.S. Gov't | 231 | 0.0 |
Amino Acid Sequence | 42 | 0.0 |
Animals | 83 | 0.0 |
Cell Line | 17 | 0.0 |
Cloning, Molecular | 26 | 0.0 |
Exons | 11 | 0.0 |
Gene Dosage | 2 | 0.0 |
Introns | 7 | 0.0 |
Molecular Sequence Data | 76 | 0.0 |
Proteins/chemistry/*genetics | 7 | 5.0 |
Repetitive Sequences, Nucleic Acid | 6 | 0.0 |
Sequence Analysis, DNA | 12 | 0.0 |
Sequence Homology, Amino Acid | 22 | 0.0 |
Alleles | 19 | 0.0 |
DNA/genetics | 7 | 0.0 |
Disease Progression | 2 | 0.0 |
Introns/genetics | 2 | 0.0 |
Phenotype | 27 | 0.0 |
Polymorphism, Genetic/genetics | 7 | 1.0 |
Reverse Transcriptase Polymerase Chain Reaction | 6 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 99 | 0.0 |
Signal Transduction | 5 | 0.0 |
Base Sequence | 59 | 0.0 |
DNA Primers | 11 | 0.0 |
Proteins/*genetics | 76 | 4.0 |
DNA-Binding Proteins/genetics | 2 | 0.0 |
Membrane Proteins/genetics/metabolism | 3 | 2.0 |
Mice | 44 | 0.0 |
Mice, Knockout | 10 | 0.0 |
Mutation/genetics | 12 | 1.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/metabolism | 2 | 66.0 |
Proteins/genetics/*metabolism | 8 | 1.0 |
Calcium Channels/genetics | 2 | 7.0 |
Comparative Study | 19 | 0.0 |
DNA Mutational Analysis/*methods | 2 | 1.0 |
Japan/epidemiology | 2 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*genetics | 86 | 78.0 |
Disease Models, Animal | 12 | 0.0 |
Membrane Proteins/*genetics | 23 | 2.0 |
Polycystic Kidney Diseases/*genetics | 22 | 59.0 |
Child | 18 | 0.0 |
Child, Preschool | 15 | 0.0 |
Cysts/*genetics | 3 | 75.0 |
Genes, Dominant | 10 | 0.0 |
Age of Onset | 10 | 0.0 |
Kidney Failure, Chronic/genetics | 2 | 22.0 |
Polymorphism, Genetic | 17 | 0.0 |
Variation (Genetics) | 6 | 0.0 |
Cell Membrane/metabolism | 7 | 0.0 |
Kidney/metabolism | 4 | 1.0 |
Membrane Proteins/genetics/*metabolism | 5 | 1.0 |
Mice, Transgenic | 3 | 0.0 |
Precipitin Tests | 4 | 0.0 |
Protein Binding | 9 | 0.0 |
Embryo/*physiology | 2 | 10.0 |
*Gene Expression Regulation, Developmental | 4 | 0.0 |
Pregnancy | 13 | 0.0 |
Protein Biosynthesis | 8 | 0.0 |
Transcription, Genetic | 8 | 0.0 |
Calcium Channel Blockers/pharmacology | 2 | 2.0 |
DNA Mutational Analysis | 20 | 0.0 |
*Mutation, Missense | 3 | 0.0 |
Protein Structure, Tertiary/genetics/physiology | 2 | 6.0 |
Signal Transduction/genetics/physiology | 2 | 4.0 |
Chromosome Mapping | 41 | 0.0 |
Organ Specificity | 5 | 0.0 |
Amino Acid Substitution/genetics | 4 | 1.0 |
Australia | 2 | 1.0 |
*Gene Duplication | 3 | 2.0 |
Glutamine | 2 | 4.0 |
Linkage (Genetics)/*genetics | 6 | 2.0 |
Mutation/*genetics | 11 | 0.0 |
Polycystic Kidney, Autosomal Dominant/genetics | 12 | 80.0 |
Sequence Alignment | 8 | 0.0 |
Epithelial Cells/physiology | 2 | 2.0 |
Membrane Proteins/genetics/physiology | 3 | 13.0 |
Morphogenesis | 2 | 0.0 |
Mutation | 33 | 0.0 |
Proteins/*genetics/*physiology | 2 | 11.0 |
Exons/genetics | 9 | 0.0 |
*Mutation | 18 | 0.0 |
DNA/analysis/blood | 2 | 11.0 |
Linkage (Genetics) | 41 | 1.0 |
Microsatellite Repeats | 8 | 0.0 |
Polymerase Chain Reaction | 33 | 0.0 |
France | 2 | 0.0 |
*Genes, Tumor Suppressor | 3 | 0.0 |
Immunohistochemistry | 10 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/metabolism/pathology | 3 | 75.0 |
Proteins/*genetics/metabolism | 5 | 1.0 |
Syndrome | 3 | 0.0 |
Polycystic Kidney, Autosomal Dominant/diagnosis/*genetics | 8 | 88.0 |
Proteins/analysis/*genetics | 2 | 6.0 |
Promoter Regions (Genetics) | 3 | 0.0 |
*Chromosomes, Human, Pair 16 | 41 | 16.0 |
Korea | 4 | 1.0 |
Microsatellite Repeats/*genetics | 3 | 1.0 |
Physical Chromosome Mapping | 2 | 0.0 |
*Polymorphism, Genetic | 6 | 0.0 |
Prevalence | 5 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/pathology | 4 | 57.0 |
Japan | 2 | 0.0 |
Sequence Deletion/genetics | 3 | 1.0 |
Cohort Studies | 2 | 0.0 |
DNA/chemistry/genetics | 4 | 0.0 |
Family Health | 6 | 0.0 |
Mutation, Missense | 3 | 0.0 |
Polymorphism, Single-Stranded Conformational | 13 | 0.0 |
Sequence Deletion | 7 | 0.0 |
Sequence Homology, Nucleic Acid | 7 | 0.0 |
*Calcium Signaling | 2 | 4.0 |
Endoplasmic Reticulum/metabolism | 2 | 0.0 |
Polycystic Kidney Diseases/*metabolism | 2 | 66.0 |
Aged, 80 and over | 10 | 0.0 |
Genetic Heterogeneity | 6 | 2.0 |
Genetic Markers | 39 | 1.0 |
Lod Score | 17 | 1.0 |
Germ-Line Mutation/genetics | 4 | 5.0 |
RNA, Messenger/genetics/metabolism | 5 | 0.0 |
Tumor Cells, Cultured | 2 | 0.0 |
Intracranial Aneurysm/complications/*genetics | 2 | 100.0 |
Polycystic Kidney, Autosomal Dominant/complications/*genetics | 5 | 100.0 |
Rats | 8 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 7 | 0.0 |
Transfection | 5 | 0.0 |
DNA Primers/genetics | 7 | 0.0 |
DNA Replication | 2 | 0.0 |
Cells, Cultured | 8 | 0.0 |
Ion Channels/physiology | 2 | 6.0 |
Membrane Proteins/*genetics/*metabolism | 2 | 4.0 |
Polycystic Kidney, Autosomal Dominant/genetics/metabolism | 3 | 75.0 |
Infant | 13 | 0.0 |
Infant, Newborn | 9 | 0.0 |
Nucleic Acid Conformation | 3 | 0.0 |
Recombination, Genetic | 8 | 0.0 |
Structure-Activity Relationship | 2 | 0.0 |
Proteins/physiology | 3 | 2.0 |
*Gene Conversion | 2 | 6.0 |
Models, Genetic | 5 | 0.0 |
Multigene Family/genetics | 2 | 1.0 |
Calcium/metabolism | 4 | 0.0 |
Gene Expression | 16 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/*metabolism | 2 | 66.0 |
Protein Transport | 2 | 0.0 |
Proteins/chemistry/genetics/*metabolism | 4 | 4.0 |
Molecular Biology | 3 | 1.0 |
Proteins/genetics/physiology | 5 | 8.0 |
Proteasome Endopeptidase Complex | 2 | 0.0 |
Protein Structure, Tertiary | 6 | 0.0 |
Gene Frequency | 6 | 0.0 |
Mental Retardation/genetics | 3 | 2.0 |
*Genes, Dominant | 5 | 2.0 |
Haplotypes | 11 | 0.0 |
Heterozygote | 7 | 0.0 |
Calcium Signaling | 2 | 2.0 |
Hamsters | 2 | 0.0 |
Polycystic Kidney, Autosomal Dominant/genetics/*metabolism | 3 | 75.0 |
Proteins/genetics/metabolism | 5 | 2.0 |
Swine | 2 | 0.0 |
Chromosomes, Human, Pair 16/genetics | 8 | 8.0 |
Chromosomes, Human, Pair 4/genetics | 5 | 6.0 |
Polymerase Chain Reaction/*methods | 2 | 0.0 |
DNA Mutational Analysis/methods | 3 | 1.0 |
DNA Restriction Enzymes/metabolism | 2 | 2.0 |
Polycystic Kidney, Autosomal Dominant/*diagnosis/*genetics | 3 | 100.0 |
Immunoblotting | 2 | 0.0 |
Phosphorylation | 4 | 0.0 |
Time Factors | 4 | 0.0 |
Cell Division | 2 | 0.0 |
Dogs | 3 | 0.0 |
Membrane Proteins/metabolism | 3 | 0.0 |
RNA, Messenger/analysis/genetics | 2 | 0.0 |
Blotting, Southern | 8 | 0.0 |
Blotting, Western | 8 | 0.0 |
Gene Deletion | 5 | 0.0 |
Genetic Complementation Test | 2 | 0.0 |
Kidney/metabolism/pathology | 2 | 6.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/metabolism/*pathology | 2 | 100.0 |
Genome, Human | 3 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/physiopathology | 3 | 75.0 |
Amino Acid Substitution | 4 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 3 | 0.0 |
Frameshift Mutation | 6 | 1.0 |
Mutagenesis, Insertional | 3 | 1.0 |
Cell Membrane/chemistry | 3 | 2.0 |
*Gene Expression | 2 | 0.0 |
Gestational Age | 3 | 0.0 |
Glycosylation | 3 | 0.0 |
Kidney/*metabolism | 2 | 1.0 |
Models, Biological | 3 | 0.0 |
Proteins/*genetics/physiology | 4 | 5.0 |
Bulgaria/epidemiology | 2 | 28.0 |
Codon, Terminator/genetics | 3 | 5.0 |
Polycystic Kidney, Autosomal Dominant/epidemiology/*genetics | 5 | 100.0 |
Chromosomes, Human, Pair 16/*genetics | 3 | 3.0 |
Epithelium/pathology | 2 | 1.0 |
*Loss of Heterozygosity | 3 | 0.0 |
Chromosomes, Human, Pair 16 | 20 | 15.0 |
Chromosomes, Human, Pair 4 | 7 | 5.0 |
English Abstract | 15 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/*pathology | 2 | 100.0 |
*Linkage (Genetics) | 14 | 1.0 |
*Membrane Glycoproteins | 2 | 0.0 |
Repressor Proteins/*genetics | 6 | 2.0 |
Tissue Distribution | 4 | 0.0 |
Fetus/metabolism | 2 | 1.0 |
Kidney/cytology/*metabolism | 2 | 9.0 |
Microscopy, Confocal | 2 | 0.0 |
Microscopy, Fluorescence | 3 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*metabolism | 4 | 100.0 |
Rabbits | 3 | 0.0 |
Membrane Proteins/chemistry/*metabolism | 2 | 3.0 |
Recombinant Proteins/metabolism | 2 | 0.0 |
DNA/analysis | 4 | 0.0 |
DNA Primers/chemistry | 2 | 0.0 |
*Frameshift Mutation | 2 | 1.0 |
Genetic Predisposition to Disease | 2 | 0.0 |
Prognosis | 4 | 0.0 |
Blood Vessels/*metabolism | 2 | 13.0 |
Loss of Heterozygosity | 4 | 0.0 |
Loss of Heterozygosity/*genetics | 2 | 2.0 |
RNA Splicing/*genetics | 2 | 2.0 |
Databases, Factual | 2 | 0.0 |
Software | 2 | 0.0 |
Polymerase Chain Reaction/methods | 3 | 0.0 |
Protein Structure, Secondary | 4 | 0.0 |
Templates, Genetic | 2 | 1.0 |
Recombinant Fusion Proteins/biosynthesis | 2 | 0.0 |
Proteins/chemistry | 4 | 8.0 |
Fluorescent Antibody Technique | 3 | 0.0 |
Liver/metabolism | 2 | 0.0 |
Membrane Proteins/*genetics/metabolism | 2 | 1.0 |
*Models, Genetic | 2 | 1.0 |
Membrane Proteins/*physiology | 3 | 2.0 |
Proteins/*physiology | 3 | 1.0 |
Mutation/physiology | 2 | 1.0 |
Kidney Failure, Chronic/etiology | 7 | 25.0 |
Survival Analysis | 4 | 0.0 |
Mutagenesis | 2 | 0.0 |
Immune Sera/immunology | 2 | 1.0 |
*Protein Biosynthesis | 5 | 1.0 |
Binding Sites | 3 | 0.0 |
Gene Library | 4 | 0.0 |
Recombinant Proteins/chemistry/metabolism | 2 | 0.0 |
*Chromosomes, Human, Pair 4 | 5 | 2.0 |
Polycystic Kidney Diseases/diagnosis/*genetics | 5 | 100.0 |
In Situ Hybridization | 2 | 0.0 |
Gene Expression Regulation/genetics | 3 | 1.0 |
JNK Mitogen-Activated Protein Kinases | 2 | 0.0 |
*Mitogen-Activated Protein Kinases | 2 | 0.0 |
Protein Kinase C/metabolism | 3 | 0.0 |
Follow-Up Studies | 2 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*complications/genetics | 2 | 100.0 |
Kidney | 2 | 0.0 |
Gene Expression/physiology | 2 | 0.0 |
*Phenotype | 2 | 0.0 |
Survival Rate | 2 | 0.0 |
DNA/genetics/isolation & purification | 2 | 0.0 |
Germ-Line Mutation | 3 | 0.0 |
*Repetitive Sequences, Nucleic Acid | 2 | 0.0 |
Creatinine/blood | 2 | 0.0 |
Cystic Fibrosis Transmembrane Conductance Regulator/genetics | 2 | 3.0 |
Magnetic Resonance Imaging | 2 | 0.0 |
Tomography, X-Ray Computed | 5 | 0.0 |
*Chromosome Mapping | 9 | 0.0 |
*Microsatellite Repeats | 3 | 1.0 |
Incidence | 2 | 0.0 |
*Point Mutation | 3 | 0.0 |
In Situ Hybridization, Fluorescence | 6 | 0.0 |
Kidney/*pathology | 2 | 3.0 |
RNA, Messenger/metabolism | 2 | 0.0 |
Liver Diseases/*genetics | 2 | 22.0 |
Calcium Channels | 2 | 28.0 |
DNA, Complementary/analysis | 2 | 0.0 |
China | 2 | 0.0 |
Polymorphism, Restriction Fragment Length | 22 | 0.0 |
*Polymorphism, Restriction Fragment Length | 7 | 0.0 |
Receptors, Somatostatin/*genetics | 2 | 7.0 |
*Prenatal Diagnosis | 2 | 0.0 |
DNA Probes | 10 | 0.0 |
Polycystic Kidney, Autosomal Dominant/*diagnosis/genetics | 4 | 100.0 |
Spain | 3 | 0.0 |
Age Factors | 3 | 0.0 |
Czech Republic/epidemiology | 2 | 13.0 |
Hypertension/complications | 3 | 5.0 |
Membrane Proteins/chemistry/*genetics | 3 | 4.0 |
Models, Molecular | 4 | 0.0 |
Nucleic Acid Hybridization | 2 | 0.0 |
Protein Conformation | 5 | 0.0 |
Enzyme Activation | 2 | 0.0 |
GTP-Binding Proteins/metabolism | 2 | 0.0 |
Polycystic Kidney, Autosomal Dominant/metabolism | 2 | 100.0 |
Polycystic Kidney, Autosomal Dominant/etiology/*genetics | 2 | 100.0 |
Fetus | 2 | 0.0 |
Prenatal Diagnosis/*methods | 2 | 1.0 |
Deoxyribonucleases, Type II Site-Specific/metabolism | 3 | 1.0 |
England | 2 | 1.0 |
Italy | 3 | 0.0 |
Point Mutation | 5 | 0.0 |
Fluorescent Dyes | 2 | 0.0 |
Reference Values | 3 | 0.0 |
Tuberous Sclerosis/*genetics | 5 | 5.0 |
Genes | 2 | 0.0 |
*Genetic Heterogeneity | 2 | 1.0 |
Mice, Inbred BALB C | 3 | 0.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Electrophoresis, Gel, Pulsed-Field | 5 | 2.0 |
Karyotyping | 4 | 0.0 |
Restriction Mapping | 9 | 0.0 |
*Gene Deletion | 2 | 0.0 |
Polymorphism, Genetic/*genetics | 2 | 0.0 |
Conserved Sequence | 2 | 0.0 |
Species Specificity | 2 | 0.0 |
Lymphocytes/metabolism | 2 | 0.0 |
DNA, Complementary | 6 | 0.0 |
Epithelium/metabolism | 2 | 0.0 |
Recombinant Proteins/biosynthesis/chemistry | 2 | 2.0 |
Subcellular Fractions/metabolism | 2 | 0.0 |
Basement Membrane/metabolism | 2 | 3.0 |
Extracellular Matrix/metabolism | 2 | 1.0 |
Fluorescent Antibody Technique, Indirect | 2 | 0.0 |
Alternative Splicing | 4 | 0.0 |
DNA, Complementary/genetics | 3 | 0.0 |
Proteins/chemistry/genetics | 2 | 7.0 |
Chromosome Mapping/methods | 3 | 2.0 |
Polycystic Kidney Diseases/*diagnosis/*genetics | 2 | 100.0 |
Genome | 2 | 0.0 |
Italy/epidemiology | 2 | 0.0 |
Ultrasonography | 3 | 3.0 |
Genetic Markers/*genetics | 2 | 1.0 |
Predictive Value of Tests | 4 | 0.0 |
Bacteriophage P1/genetics | 2 | 8.0 |
Blotting, Northern | 3 | 0.0 |
Sequence Tagged Sites | 2 | 0.0 |
Cosmids/genetics | 3 | 5.0 |
Hybrid Cells | 7 | 0.0 |
Chromosome Aberrations/*genetics | 2 | 1.0 |
Chromosome Disorders | 2 | 0.0 |
Genes, Dominant/*genetics | 3 | 3.0 |
*Genes | 2 | 0.0 |
Cosmids | 3 | 0.0 |
Translocation, Genetic | 4 | 0.0 |
DNA, Satellite/*analysis | 3 | 16.0 |
Hypertension/etiology | 2 | 4.0 |
Kidney/pathology | 2 | 1.0 |
Polycystic Kidney, Autosomal Dominant/*genetics/ultrasonography | 3 | 75.0 |
RNA, Messenger/genetics | 2 | 0.0 |
Codon/genetics | 2 | 0.0 |
Cyprus/epidemiology | 2 | 20.0 |
DNA/*analysis | 4 | 1.0 |
*Sequence Deletion | 3 | 0.0 |
*Introns | 2 | 0.0 |
Prenatal Diagnosis | 2 | 1.0 |
DNA, Satellite/*genetics | 2 | 3.0 |
*Linkage Disequilibrium | 4 | 2.0 |
*Multigene Family | 3 | 0.0 |
Chi-Square Distribution | 3 | 0.0 |
*Chromosomes, Human, Pair 16/ultrastructure | 2 | 66.0 |
*Genetic Markers | 3 | 0.0 |
Evaluation Studies | 2 | 0.0 |
Risk Factors | 4 | 0.0 |
Family | 3 | 0.0 |
Israel/epidemiology | 2 | 4.0 |
Colorado/epidemiology | 2 | 22.0 |
Polycystic Kidney, Autosomal Dominant/complications/*etiology/mortality | 2 | 100.0 |
Sex Factors | 2 | 0.0 |
*Restriction Mapping | 2 | 5.0 |
Globins/*genetics | 2 | 1.0 |
Genetic Vectors | 2 | 0.0 |
Kluyveromyces/*genetics | 2 | 100.0 |
*Recombination, Genetic | 2 | 0.0 |
*Variation (Genetics) | 2 | 0.0 |
*DNA Probes | 4 | 8.0 |
Hybrid Cells/cytology | 2 | 6.0 |
Severity of Illness Index | 3 | 0.0 |
Cilia/*physiology | 2 | 25.0 |
Recombinant Fusion Proteins/metabolism | 2 | 0.0 |
Gene Expression Regulation | 2 | 0.0 |
Signal Transduction/physiology | 2 | 0.0 |
Ryanodine Receptor Calcium Release Channel/metabolism | 2 | 18.0 |
