MeSH term
Frequency | Condition_Probility | Blotting, Western | 6 | 0.0 |
Cell Line | 5 | 0.0 |
Cyclic AMP/metabolism | 6 | 1.0 |
Humans | 43 | 0.0 |
Phosphodiesterase Inhibitors/*pharmacology | 7 | 14.0 |
Research Support, Non-U.S. Gov't | 24 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 8 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 6 | 0.0 |
Rolipram/pharmacology | 6 | 31.0 |
Up-Regulation | 4 | 0.0 |
Cells, Cultured | 5 | 0.0 |
Cyclic AMP/*metabolism | 4 | 1.0 |
Dose-Response Relationship, Drug | 3 | 0.0 |
Phosphodiesterase Inhibitors/pharmacology | 10 | 9.0 |
Theophylline/pharmacology | 2 | 5.0 |
Tumor Cells, Cultured | 3 | 0.0 |
3',5'-Cyclic-Nucleotide Phosphodiesterase/*antagonists & inhibitors | 3 | 20.0 |
Male | 7 | 0.0 |
3',5'-Cyclic-Nucleotide Phosphodiesterase/*metabolism | 3 | 27.0 |
Purinones/pharmacology | 2 | 18.0 |
Rolipram/*pharmacology | 3 | 75.0 |
3',5'-Cyclic-Nucleotide Phosphodiesterase/*genetics/metabolism | 2 | 16.0 |
Amino Acid Sequence | 10 | 0.0 |
Animals | 18 | 0.0 |
Base Sequence | 10 | 0.0 |
COS Cells | 3 | 0.0 |
Cloning, Molecular | 4 | 0.0 |
Enzyme Stability | 2 | 1.0 |
Exons | 2 | 0.0 |
Introns | 2 | 0.0 |
Mice | 5 | 0.0 |
Molecular Sequence Data | 14 | 0.0 |
Promoter Regions (Genetics)/*genetics | 2 | 0.0 |
Rats | 10 | 0.0 |
Sequence Homology, Amino Acid | 3 | 0.0 |
Transfection | 3 | 0.0 |
Binding Sites | 3 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 3 | 0.0 |
Enzyme Inhibitors/pharmacology | 5 | 0.0 |
Kinetics | 7 | 0.0 |
Mutagenesis, Site-Directed | 2 | 0.0 |
Protein Binding | 3 | 0.0 |
Protein Conformation | 2 | 0.0 |
Protein Structure, Tertiary | 2 | 0.0 |
Binding, Competitive | 3 | 0.0 |
DNA, Complementary/genetics | 2 | 0.0 |
Gene Expression Regulation, Enzymologic/drug effects | 4 | 2.0 |
Polymerase Chain Reaction | 2 | 0.0 |
RNA, Messenger/metabolism | 6 | 0.0 |
Sequence Alignment | 2 | 0.0 |
3',5'-Cyclic-Nucleotide Phosphodiesterase/*genetics/*metabolism | 2 | 50.0 |
Comparative Study | 5 | 0.0 |
Female | 5 | 0.0 |
Gene Expression | 4 | 0.0 |
Middle Aged | 2 | 0.0 |
Cyclic AMP/physiology | 3 | 2.0 |
Sequence Analysis, DNA | 3 | 0.0 |
Substrate Specificity | 4 | 0.0 |
Adult | 2 | 0.0 |
In Vitro | 3 | 0.0 |
Enzyme Activation/drug effects | 3 | 0.0 |
Isoenzymes/antagonists & inhibitors/metabolism | 2 | 2.0 |
Lipopolysaccharides/pharmacology | 5 | 0.0 |
Catalysis | 2 | 0.0 |
Structure-Activity Relationship | 2 | 0.0 |
3',5'-Cyclic-Nucleotide Phosphodiesterase/chemistry/*genetics | 2 | 66.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 7 | 0.0 |
Anti-Inflammatory Agents, Non-Steroidal/*pharmacology | 2 | 1.0 |
Lymphocyte Activation/drug effects | 2 | 0.0 |
3',5'-Cyclic-Nucleotide Phosphodiesterase/*chemistry | 2 | 50.0 |
Brain/enzymology | 2 | 1.0 |
Carrier Proteins/genetics | 2 | 0.0 |
Cyclic AMP/*pharmacology | 3 | 5.0 |
Isoenzymes/metabolism | 3 | 0.0 |
Recombinant Fusion Proteins/metabolism | 2 | 0.0 |
src Homology Domains/*genetics | 2 | 6.0 |
src-Family Kinases/metabolism | 2 | 1.0 |
Pregnancy | 3 | 0.0 |
Genetic Vectors | 2 | 0.0 |
Isoenzymes/*genetics/metabolism | 2 | 3.0 |
Rabbits | 2 | 0.0 |
Cell Line, Tumor | 2 | 0.0 |
Pyrrolidinones/pharmacology | 4 | 7.0 |
Rolipram | 6 | 23.0 |
Tumor Necrosis Factor-alpha/secretion | 2 | 1.0 |
Monocytes/drug effects/*enzymology | 2 | 22.0 |
Phosphoric Diester Hydrolases/*metabolism | 2 | 8.0 |
Jurkat Cells | 2 | 0.0 |
Bronchodilator Agents/*pharmacology | 2 | 28.0 |
Superoxides/metabolism | 2 | 0.0 |
Immunohistochemistry | 2 | 0.0 |
RNA, Messenger/genetics/metabolism | 2 | 0.0 |
Phosphoric Diester Hydrolases/genetics/*metabolism | 2 | 50.0 |
3',5'-Cyclic-Nucleotide Phosphodiesterase/genetics/*metabolism | 2 | 20.0 |
Gene Expression/drug effects | 2 | 0.0 |
