MeSH term
Frequency | Condition_Probility | Chromones/pharmacology | 2 | 0.0 |
Enzyme Inhibitors/pharmacology | 9 | 0.0 |
Humans | 100 | 0.0 |
Morpholines/pharmacology | 2 | 0.0 |
Signal Transduction/physiology | 2 | 0.0 |
p38 Mitogen-Activated Protein Kinases | 7 | 1.0 |
Animals | 52 | 0.0 |
Calcium/metabolism | 3 | 0.0 |
Cell Line | 32 | 0.0 |
Enzyme Activation/drug effects | 4 | 0.0 |
MAP Kinase Kinase 1 | 4 | 2.0 |
MAP Kinase Kinase 2 | 2 | 4.0 |
Mitogen-Activated Protein Kinase Kinases/metabolism | 3 | 1.0 |
Protein-Serine-Threonine Kinases/*metabolism | 34 | 4.0 |
Protein-Tyrosine Kinase/metabolism | 6 | 0.0 |
Rats | 8 | 0.0 |
Research Support, Non-U.S. Gov't | 66 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 8 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 67 | 0.0 |
Signal Transduction/drug effects/physiology | 2 | 0.0 |
Tumor Cells, Cultured | 14 | 0.0 |
cdc42 GTP-Binding Protein/*metabolism | 7 | 8.0 |
Amino Acid Motifs | 2 | 0.0 |
Amino Acid Sequence | 21 | 0.0 |
Blotting, Northern | 3 | 0.0 |
Brain/*enzymology | 2 | 1.0 |
Chromosome Mapping | 3 | 0.0 |
Cloning, Molecular | 8 | 0.0 |
DNA, Complementary/metabolism | 5 | 0.0 |
GTP Phosphohydrolases/metabolism | 5 | 3.0 |
Mitogen-Activated Protein Kinase 8 | 2 | 2.0 |
Mitogen-Activated Protein Kinases/metabolism | 12 | 1.0 |
Models, Genetic | 3 | 0.0 |
Molecular Sequence Data | 25 | 0.0 |
Phosphorylation | 32 | 0.0 |
Precipitin Tests | 9 | 0.0 |
Protein Binding | 23 | 0.0 |
Protein Structure, Tertiary | 9 | 0.0 |
RNA, Messenger/metabolism | 6 | 0.0 |
Tissue Distribution | 4 | 0.0 |
Transfection | 27 | 0.0 |
cdc42 GTP-Binding Protein/metabolism | 8 | 6.0 |
Binding Sites | 11 | 0.0 |
Cell Line, Tumor | 11 | 0.0 |
Phosphoproteins/*metabolism | 2 | 0.0 |
Protein-Serine-Threonine Kinases/*physiology | 4 | 3.0 |
Signal Transduction | 29 | 0.0 |
Base Sequence | 9 | 0.0 |
Enzyme Activation | 36 | 1.0 |
Hela Cells | 16 | 0.0 |
Phenotype | 7 | 0.0 |
Polymerase Chain Reaction | 4 | 0.0 |
Up-Regulation | 6 | 0.0 |
Cell Transformation, Neoplastic | 2 | 0.0 |
Comparative Study | 6 | 0.0 |
Models, Biological | 11 | 0.0 |
Blotting, Western | 9 | 0.0 |
*MAP Kinase Signaling System | 2 | 1.0 |
Mitogen-Activated Protein Kinases/*metabolism | 5 | 0.0 |
Mutation | 14 | 0.0 |
Protein-Serine-Threonine Kinases/genetics/*metabolism | 9 | 3.0 |
Proto-Oncogene Proteins c-raf/*metabolism | 4 | 11.0 |
Serine/metabolism | 2 | 0.0 |
Threonine/metabolism | 2 | 2.0 |
Cells, Cultured | 11 | 0.0 |
Ligands | 3 | 0.0 |
Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism | 2 | 2.0 |
rac1 GTP-Binding Protein/physiology | 2 | 11.0 |
Cell Cycle Proteins/metabolism | 7 | 2.0 |
Dimerization | 3 | 0.0 |
Guanine Nucleotide Exchange Factors/metabolism | 3 | 6.0 |
Protein-Serine-Threonine Kinases/chemistry/genetics/*metabolism | 7 | 14.0 |
rac1 GTP-Binding Protein/*metabolism | 5 | 5.0 |
JNK Mitogen-Activated Protein Kinases | 7 | 1.0 |
Sequence Homology, Amino Acid | 6 | 0.0 |
rac GTP-Binding Proteins/metabolism | 4 | 6.0 |
DNA Primers | 4 | 0.0 |
Nocodazole/pharmacology | 2 | 1.0 |
Tetradecanoylphorbol Acetate/pharmacology | 4 | 0.0 |
3T3 Cells | 7 | 0.0 |
Actins/metabolism | 4 | 0.0 |
*Adaptor Proteins, Signal Transducing | 6 | 0.0 |
COS Cells | 15 | 0.0 |
Carrier Proteins/*metabolism | 2 | 0.0 |
Cell Adhesion | 3 | 0.0 |
Cell Membrane/metabolism | 4 | 0.0 |
Cercopithecus aethiops | 4 | 0.0 |
Mice | 20 | 0.0 |
Oncogene Proteins/*metabolism | 4 | 4.0 |
Pseudopodia/metabolism | 2 | 6.0 |
rho GTP-Binding Proteins/*metabolism | 2 | 2.0 |
*Gene Expression Regulation, Neoplastic | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 5 | 0.0 |
Binding, Competitive | 3 | 0.0 |
Cell Nucleus/metabolism | 2 | 0.0 |
Cytoskeleton/metabolism | 7 | 2.0 |
Down-Regulation | 2 | 0.0 |
Genes, Dominant | 4 | 0.0 |
Lipopolysaccharides/metabolism | 2 | 1.0 |
Male | 4 | 0.0 |
*Membrane Proteins | 2 | 0.0 |
Plasmids/metabolism | 6 | 0.0 |
Dose-Response Relationship, Drug | 5 | 0.0 |
Peptides/chemistry | 2 | 0.0 |
*Apoptosis | 2 | 0.0 |
DNA Fragmentation | 2 | 0.0 |
Gene Deletion | 2 | 0.0 |
Protein-Serine-Threonine Kinases/metabolism | 12 | 1.0 |
Time Factors | 8 | 0.0 |
src Homology Domains | 6 | 1.0 |
Cytoskeletal Proteins/metabolism | 2 | 0.0 |
Glutathione Transferase/genetics/metabolism | 2 | 1.0 |
Microfilament Proteins/metabolism | 2 | 2.0 |
Phosphotyrosine/metabolism | 3 | 0.0 |
Proteins/metabolism | 3 | 0.0 |
Recombinant Fusion Proteins/genetics/metabolism | 5 | 0.0 |
*Signal Transduction | 6 | 0.0 |
Two-Hybrid System Techniques | 6 | 0.0 |
NF-kappa B/metabolism | 3 | 0.0 |
Protein-Serine-Threonine Kinases/physiology | 2 | 2.0 |
Trans-Activation (Genetics) | 2 | 0.0 |
Transcription Factor AP-1/metabolism | 2 | 0.0 |
cdc42 GTP-Binding Protein/physiology | 2 | 11.0 |
1-Phosphatidylinositol 3-Kinase/metabolism | 5 | 0.0 |
Androstadienes/pharmacology | 3 | 1.0 |
Apoptosis | 2 | 0.0 |
Cell Division | 7 | 0.0 |
Cell Movement | 10 | 1.0 |
Cell Survival | 4 | 0.0 |
DNA/metabolism | 4 | 0.0 |
Dogs | 3 | 0.0 |
Proto-Oncogene Proteins/metabolism | 3 | 0.0 |
Recombinant Proteins/metabolism | 6 | 0.0 |
Cell Movement/*physiology | 2 | 0.0 |
Immunoblotting | 3 | 0.0 |
Platelet-Derived Growth Factor/pharmacology | 2 | 1.0 |
Transduction, Genetic | 2 | 0.0 |
DNA-Binding Proteins/metabolism | 2 | 0.0 |
Genes, Reporter | 2 | 0.0 |
Nuclear Proteins/metabolism | 2 | 0.0 |
Promoter Regions (Genetics) | 5 | 0.0 |
Female | 15 | 0.0 |
*Gene Expression Regulation, Enzymologic | 4 | 0.0 |
Kinetics | 5 | 0.0 |
cdc42 GTP-Binding Protein/genetics/metabolism | 2 | 8.0 |
*Gene Expression Regulation | 3 | 0.0 |
Mitogen-Activated Protein Kinase 1/metabolism | 4 | 1.0 |
Recombinant Proteins/chemistry | 2 | 0.0 |
Transcription Factors/*metabolism | 3 | 0.0 |
Substrate Specificity | 5 | 0.0 |
Amino Acid Substitution | 3 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 3 | 0.0 |
Epidermal Growth Factor/pharmacology | 3 | 0.0 |
Zinc Fingers | 2 | 0.0 |
In Vitro | 4 | 0.0 |
Mitogen-Activated Protein Kinase 3 | 4 | 0.0 |
rac1 GTP-Binding Protein/metabolism | 6 | 6.0 |
Oncogene Proteins/metabolism | 3 | 3.0 |
Cell Cycle Proteins/genetics/*metabolism | 2 | 1.0 |
Guanine Nucleotide Exchange Factors/genetics/*metabolism | 2 | 8.0 |
Jurkat Cells | 3 | 0.0 |
Phosphoproteins/metabolism | 2 | 0.0 |
Receptors, Antigen, T-Cell/*metabolism | 2 | 1.0 |
Breast Neoplasms/metabolism | 2 | 1.0 |
Laminin/metabolism | 2 | 1.0 |
Mice, Transgenic | 3 | 0.0 |
Mutagenesis | 2 | 0.0 |
*Up-Regulation | 2 | 0.0 |
Fluorescent Antibody Technique | 4 | 0.0 |
Proto-Oncogene Proteins c-raf/metabolism | 2 | 2.0 |
Transcription, Genetic | 4 | 0.0 |
ras Proteins/metabolism | 2 | 1.0 |
Neoplasm Invasiveness | 3 | 0.0 |
Green Fluorescent Proteins | 2 | 0.0 |
Pregnancy | 3 | 0.0 |
Protein Kinases/*metabolism | 2 | 0.0 |
Phosphorylation/drug effects | 3 | 0.0 |
rac GTP-Binding Proteins/*metabolism | 2 | 3.0 |
Sequence Deletion | 2 | 0.0 |
Cytoskeleton/*physiology | 2 | 5.0 |
Mutagenesis, Site-Directed | 3 | 0.0 |
*Saccharomyces cerevisiae Proteins | 5 | 0.0 |
Adult | 2 | 0.0 |
Cell Polarity | 2 | 1.0 |
Microscopy, Confocal | 4 | 0.0 |
Microscopy, Fluorescence | 5 | 0.0 |
N-Formylmethionine Leucyl-Phenylalanine/pharmacology | 2 | 0.0 |
cdc42 GTP-Binding Protein | 5 | 5.0 |
rac GTP-Binding Proteins | 8 | 4.0 |
Gene Expression Regulation, Neoplastic | 4 | 0.0 |
Glutathione Transferase/metabolism | 6 | 0.0 |
Immunohistochemistry | 4 | 0.0 |
Serine/chemistry | 4 | 2.0 |
GTP-Binding Proteins/metabolism | 5 | 1.0 |
Hamsters | 4 | 0.0 |
Myosin Light Chains/*metabolism | 2 | 14.0 |
Gene Expression Regulation | 3 | 0.0 |
Oligonucleotide Array Sequence Analysis | 4 | 0.0 |
Cell Line, Transformed | 2 | 0.0 |
Proteins/*metabolism | 2 | 0.0 |
Recombinant Fusion Proteins/metabolism | 3 | 0.0 |
Receptor, Epidermal Growth Factor/metabolism | 3 | 0.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/*metabolism | 4 | 1.0 |
DNA-Binding Proteins/*metabolism | 2 | 0.0 |
*Mitogen-Activated Protein Kinases | 3 | 0.0 |
GTP-Binding Proteins/*metabolism | 3 | 0.0 |
Guanosine Triphosphate/metabolism | 2 | 0.0 |
rhoA GTP-Binding Protein | 2 | 2.0 |
DNA, Neoplasm/analysis | 2 | 0.0 |
Cytoskeleton/metabolism/ultrastructure | 2 | 9.0 |
Vinculin/metabolism | 2 | 8.0 |
cdc42 GTP-Binding Protein, Saccharomyces cerevisiae | 3 | 10.0 |
Recombinant Proteins/biosynthesis/metabolism | 2 | 1.0 |
rho GTP-Binding Proteins | 2 | 7.0 |
Protein Kinases/metabolism | 2 | 0.0 |
Guanine Nucleotide Exchange Factors/*metabolism | 2 | 4.0 |
Protein Transport | 2 | 0.0 |
Quinazolines/*pharmacology | 2 | 2.0 |
Actins/*metabolism | 2 | 0.0 |
Recombinant Fusion Proteins/chemistry/genetics/metabolism | 2 | 1.0 |
NIH 3T3 Cells | 2 | 0.0 |
Cell Movement/*drug effects | 2 | 2.0 |
In Situ Hybridization, Fluorescence | 2 | 0.0 |
Protein-Serine-Threonine Kinases/*genetics/metabolism | 2 | 3.0 |
Enzyme Inhibitors/*pharmacology | 2 | 0.0 |
