MeSH term
Frequency | Condition_Probility | Animals | 56 | 0.0 |
Gene Expression Regulation/*physiology | 2 | 0.0 |
Humans | 82 | 0.0 |
Carrier Proteins/*metabolism | 7 | 0.0 |
Cells, Cultured | 13 | 0.0 |
Fibroblasts | 8 | 1.0 |
Glycoproteins/metabolism | 2 | 1.0 |
Immunohistochemistry | 7 | 0.0 |
Mice | 17 | 0.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Mice, Mutant Strains | 4 | 0.0 |
Nerve Tissue Proteins/*metabolism | 2 | 0.0 |
Neurons/*metabolism | 2 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 43 | 0.0 |
Biological Transport | 13 | 0.0 |
Cell Membrane/chemistry/metabolism | 2 | 4.0 |
Cholesterol/chemistry/*metabolism | 2 | 28.0 |
Fibroblasts/metabolism | 6 | 0.0 |
Microscopy, Fluorescence | 10 | 0.0 |
Research Support, Non-U.S. Gov't | 64 | 0.0 |
*Disease Models, Animal | 3 | 0.0 |
Genes, Recessive/genetics | 2 | 2.0 |
Heterozygote Detection | 2 | 0.0 |
Mice, Inbred BALB C | 8 | 0.0 |
Niemann-Pick Diseases/*genetics/physiopathology | 2 | 100.0 |
Proteins/genetics | 5 | 0.0 |
Carrier Proteins/*genetics | 4 | 0.0 |
DNA Mutational Analysis | 11 | 0.0 |
Female | 20 | 0.0 |
Genotype | 10 | 0.0 |
Male | 14 | 0.0 |
Membrane Glycoproteins/*genetics | 4 | 0.0 |
Mutation/*genetics | 5 | 0.0 |
Niemann-Pick Diseases/*genetics | 12 | 92.0 |
Pedigree | 2 | 0.0 |
Blotting, Western | 7 | 0.0 |
Centrifugation, Density Gradient | 2 | 0.0 |
Cholesterol/metabolism | 17 | 5.0 |
Glycosylation | 3 | 0.0 |
Microscopy, Electron | 2 | 0.0 |
Sterols/*metabolism | 6 | 18.0 |
Time Factors | 4 | 0.0 |
Adult | 10 | 0.0 |
Child | 8 | 0.0 |
Middle Aged | 2 | 0.0 |
Risk Factors | 2 | 0.0 |
CHO Cells | 21 | 0.0 |
Endosomes/*metabolism | 9 | 8.0 |
Hamsters | 23 | 0.0 |
Niemann-Pick Diseases/*metabolism | 11 | 68.0 |
Amino Acid Sequence | 19 | 0.0 |
COS Cells | 4 | 0.0 |
Carrier Proteins/genetics/*metabolism | 6 | 1.0 |
Cell Membrane/metabolism | 8 | 0.0 |
Fibroblasts/cytology/metabolism | 2 | 1.0 |
Membrane Glycoproteins/genetics/*metabolism | 4 | 2.0 |
Molecular Sequence Data | 24 | 0.0 |
Protein Structure, Secondary | 3 | 0.0 |
Protein Structure, Tertiary | 11 | 0.0 |
Protein Transport/physiology | 3 | 2.0 |
Base Sequence | 13 | 0.0 |
Cholesterol/*metabolism | 23 | 9.0 |
Cholesterol Esters/metabolism | 4 | 3.0 |
DNA Primers | 5 | 0.0 |
Glycoproteins/*physiology | 2 | 3.0 |
Glycosphingolipids/metabolism | 2 | 16.0 |
Infant, Newborn | 5 | 0.0 |
Neurons/metabolism/pathology | 3 | 4.0 |
Age of Onset | 3 | 0.0 |
Cell Line | 7 | 0.0 |
Child, Preschool | 11 | 0.0 |
Consanguinity | 2 | 0.0 |
Esterification | 5 | 6.0 |
Phenotype | 12 | 0.0 |
Cats | 5 | 1.0 |
Disease Models, Animal | 4 | 0.0 |
Carrier Proteins/*chemistry/genetics/*metabolism | 3 | 7.0 |
Luminescent Proteins/genetics/metabolism | 3 | 1.0 |
Membrane Glycoproteins/*chemistry/genetics/*metabolism | 3 | 30.0 |
Molecular Structure | 2 | 0.0 |
Niemann-Pick Diseases | 2 | 100.0 |
Protein Binding | 2 | 0.0 |
Recombinant Fusion Proteins/genetics/metabolism | 4 | 0.0 |
Membrane Glycoproteins/*metabolism | 5 | 1.0 |
Alleles | 4 | 0.0 |
Endosomes/metabolism | 9 | 7.0 |
Golgi Apparatus/metabolism | 3 | 1.0 |
Kinetics | 2 | 0.0 |
Lysosomes/metabolism | 12 | 8.0 |
Sphingolipids/*metabolism | 3 | 30.0 |
Adolescent | 6 | 0.0 |
Exons/genetics | 3 | 0.0 |
Infant | 5 | 0.0 |
Niemann-Pick Diseases/*genetics/*metabolism/physiopathology | 2 | 100.0 |
Polymorphism, Single-Stranded Conformational | 4 | 0.0 |
Protein Conformation | 2 | 0.0 |
Structure-Activity Relationship | 4 | 0.0 |
Androstenes/pharmacology | 10 | 71.0 |
Anticholesteremic Agents/pharmacology | 4 | 9.0 |
Glycolipids/metabolism | 2 | 10.0 |
Niemann-Pick Diseases/metabolism | 2 | 50.0 |
Carrier Proteins/metabolism | 2 | 0.0 |
Cell Compartmentation | 5 | 1.0 |
Endocytosis | 5 | 1.0 |
Endoplasmic Reticulum/metabolism | 9 | 3.0 |
Green Fluorescent Proteins | 4 | 0.0 |
Luminescent Proteins/metabolism | 2 | 0.0 |
Membrane Glycoproteins/metabolism | 6 | 1.0 |
Carrier Proteins/genetics/*physiology | 3 | 3.0 |
Lipids/metabolism | 4 | 1.0 |
Membrane Glycoproteins/genetics/*physiology | 3 | 4.0 |
Mutation | 17 | 0.0 |
Niemann-Pick Diseases/genetics/*physiopathology | 2 | 100.0 |
Lipids/*metabolism | 3 | 1.0 |
Antigens, CD/metabolism | 2 | 0.0 |
Comparative Study | 6 | 0.0 |
Filipin/metabolism | 4 | 57.0 |
Niemann-Pick Diseases/genetics/*metabolism/*pathology | 2 | 66.0 |
Intracellular Membranes/metabolism | 3 | 1.0 |
Lipoproteins, LDL Cholesterol/metabolism | 6 | 17.0 |
Models, Biological | 7 | 0.0 |
Models, Molecular | 3 | 0.0 |
Niemann-Pick Diseases/*genetics/metabolism | 3 | 100.0 |
Transport Vesicles/*metabolism | 2 | 20.0 |
*Carrier Proteins | 23 | 3.0 |
*Membrane Glycoproteins | 21 | 2.0 |
Membrane Proteins/chemistry | 3 | 6.0 |
Niemann-Pick Diseases/genetics/*metabolism | 4 | 100.0 |
Recombinant Proteins/metabolism | 4 | 0.0 |
Sequence Alignment | 4 | 0.0 |
Sequence Homology, Amino Acid | 10 | 0.0 |
DNA, Complementary/genetics | 3 | 0.0 |
Histocytochemistry | 2 | 0.0 |
Transfection | 12 | 0.0 |
Homeostasis | 3 | 0.0 |
Lipoproteins/metabolism | 3 | 2.0 |
Lipoproteins, LDL/metabolism | 4 | 1.0 |
Niemann-Pick Diseases/genetics | 2 | 66.0 |
Proteins/genetics/*metabolism | 6 | 1.0 |
Progesterone/pharmacology | 7 | 6.0 |
Tumor Cells, Cultured | 3 | 0.0 |
Proteins/*genetics | 5 | 0.0 |
*Transcription, Genetic | 2 | 0.0 |
Biological Transport/drug effects | 3 | 1.0 |
Proteins/*metabolism | 2 | 0.0 |
Lysosomes | 2 | 28.0 |
DNA, Complementary | 2 | 0.0 |
Exons | 4 | 0.0 |
Gene Expression Profiling | 2 | 0.0 |
ATP-Binding Cassette Transporters/*pharmacology | 2 | 66.0 |
Carcinoma, Hepatocellular/*metabolism/pathology | 2 | 3.0 |
Down-Regulation | 2 | 0.0 |
Fibroblasts/*metabolism/pathology | 2 | 8.0 |
Hydroxymethylglutaryl-CoA Synthase/metabolism | 2 | 50.0 |
Hypercholesterolemia/metabolism/pathology | 2 | 100.0 |
Liver Neoplasms/metabolism/pathology | 2 | 12.0 |
Niemann-Pick Diseases/metabolism/pathology | 4 | 100.0 |
RNA, Messenger/genetics/metabolism | 2 | 0.0 |
Receptors, LDL/genetics/*metabolism | 2 | 7.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 2 | 0.0 |
Up-Regulation | 2 | 0.0 |
Chromosome Mapping | 2 | 0.0 |
Conserved Sequence | 4 | 0.0 |
Evolution, Molecular | 2 | 0.0 |
Expressed Sequence Tags | 2 | 0.0 |
Introns | 3 | 0.0 |
Intracellular Fluid/metabolism | 2 | 1.0 |
Cloning, Molecular | 4 | 0.0 |
Lipoproteins, LDL Cholesterol/*metabolism | 3 | 15.0 |
Carrier Proteins/genetics | 3 | 0.0 |
Glycoproteins/genetics | 2 | 2.0 |
Membrane Glycoproteins/genetics | 3 | 1.0 |
Lysosomes/*metabolism | 3 | 3.0 |
Amino Acid Substitution | 2 | 0.0 |
Binding Sites | 2 | 0.0 |
Nova Scotia | 2 | 50.0 |
Antibodies | 3 | 0.0 |
Axons/pathology/ultrastructure | 2 | 28.0 |
Nerve Degeneration/metabolism/pathology | 2 | 18.0 |
Neuroglia/metabolism/pathology | 2 | 14.0 |
Polymerase Chain Reaction | 4 | 0.0 |
Pregnancy | 3 | 0.0 |
Chromosomes, Human, Pair 18 | 2 | 1.0 |
Fibroblasts/*metabolism | 3 | 1.0 |
Genetic Screening | 2 | 0.0 |
Hydroxymethylglutaryl CoA Reductases/chemistry | 2 | 100.0 |
Proteins/chemistry/*genetics/physiology | 2 | 11.0 |
Microscopy, Confocal | 2 | 0.0 |
Phosphorylation | 2 | 0.0 |
Glycoproteins/genetics/*metabolism | 2 | 5.0 |
Glycoproteins/*metabolism | 2 | 1.0 |
Biological Transport/physiology | 2 | 1.0 |
Niemann-Pick Diseases/genetics/metabolism | 2 | 50.0 |
Enzyme Inhibitors/pharmacology | 3 | 0.0 |
Sterol O-Acyltransferase/antagonists & inhibitors/metabolism | 2 | 50.0 |
Glycoproteins/*genetics | 3 | 1.0 |
Mutation/genetics | 2 | 0.0 |
Carrier Proteins/chemistry/*genetics | 2 | 3.0 |
Gene Frequency | 2 | 0.0 |
Membrane Glycoproteins/chemistry/*genetics | 2 | 5.0 |
*Mutation | 2 | 0.0 |
Heterozygote | 2 | 0.0 |
Carrier Proteins/genetics/metabolism | 4 | 2.0 |
Cyclodextrins/metabolism | 2 | 25.0 |
Membrane Glycoproteins/genetics/metabolism | 4 | 5.0 |
Forecasting | 2 | 0.0 |
Glycoproteins/genetics/metabolism | 2 | 8.0 |
Protein Transport | 2 | 0.0 |
