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Taipei Medical University

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Gene Symbol
Gene NameAliasesPrevious_Symbol

MSH2

mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)HNPCCmutS (E. coli) homolog 2 (colon cancer, nonpolyposis type 1)


Gene MSH2 gene interaction
View Neighborhood Gene

Result number fewer <<<< << < ALL > >> >>> more

MeSH term
FrequencyCondition_Probility

Adult

1180.0

Aged

890.0

Aged, 80 and over

440.0

Barrett Esophagus/*genetics

225.0

*Base Pair Mismatch

4246.0

*DNA Repair

537.0

DNA-Binding Proteins/analysis

45.0

Female

1910.0

Humans

3690.0

Immunohistochemistry

670.0

Male

1710.0

Middle Aged

1470.0

Neoplasm Proteins/analysis

82.0

Proto-Oncogene Proteins/analysis

105.0

Research Support, Non-U.S. Gov't

2460.0

Age of Onset

171.0

Amino Acid Sequence

220.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics/pathology

440.0

DNA Mutational Analysis

591.0

DNA, Neoplasm/chemistry/genetics

32.0

*DNA-Binding Proteins

1518.0

Family Health

131.0

Genotype

150.0

Molecular Sequence Data

590.0

Mutation

410.0

Neoplasm Proteins/genetics

357.0

Phenotype

330.0

Proto-Oncogene Proteins/genetics

346.0

Sequence Homology, Amino Acid

120.0

Adenosinetriphosphatase/genetics/metabolism

28.0

*Aneuploidy

33.0

Animals

660.0

*DNA Repair Enzymes

3031.0

DNA-Binding Proteins/genetics/metabolism

71.0

Exons

170.0

Mice

510.0

Mice, Inbred C57BL

140.0

Mice, Mutant Strains

40.0

Microsatellite Repeats

494.0

Neoplasm Proteins/genetics/metabolism

65.0

Sequence Analysis

20.0

*Germ-Line Mutation

296.0

Microsatellite Repeats/genetics

307.0

Neoplasm Proteins/biosynthesis/*genetics

66.0

Predictive Value of Tests

60.0

Proto-Oncogene Proteins/biosynthesis/*genetics

69.0

Mammals

20.0

Oxidation-Reduction

20.0

Base Sequence

480.0

Cell Line

110.0

Chromosome Aberrations

30.0

DNA Mutational Analysis/*methods

53.0

Genes, BRCA1

31.0

Polymerase Chain Reaction/*methods

71.0

Polymorphism, Single Nucleotide

20.0

Sensitivity and Specificity

180.0

Sequence Deletion

80.0

Tumor Cells, Cultured

190.0

Alleles

180.0

Colorectal Neoplasms/*genetics

198.0

Endometrial Neoplasms/*genetics

510.0

Germ-Line Mutation

328.0

*Microsatellite Repeats

2511.0

Phosphoric Monoester Hydrolases/genetics

22.0

Research Support, U.S. Gov't, P.H.S.

1100.0

Trinucleotide Repeat Expansion

25.0

Tumor Suppressor Proteins/genetics

22.0

DNA/*metabolism

20.0

DNA Damage

80.0

Models, Biological

40.0

Neoplasms/*genetics

31.0

Research Support, U.S. Gov't, Non-P.H.S.

140.0

Base Pair Mismatch

5130.0

DNA Repair

568.0

Immunohistochemistry/methods

30.0

Tumor Markers, Biological/*analysis

40.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics

5052.0

DNA-Binding Proteins/*genetics/physiology

33.0

Mutation, Missense

60.0

Proto-Oncogene Proteins/physiology

32.0

Adolescent

160.0

Antineoplastic Combined Chemotherapy Protocols/*therapeutic use

20.0

DNA, Neoplasm/*genetics

73.0

DNA-Binding Proteins/metabolism

80.0

Disease-Free Survival

50.0

Drug Resistance, Neoplasm

50.0

Microsatellite Repeats/*genetics

3011.0

Neoplasm Proteins/metabolism

71.0

Proto-Oncogene Proteins/metabolism

60.0

Base Pair Mismatch/*genetics

2443.0

Neoplasms, Multiple Primary/*genetics

37.0

Cell Nucleus/metabolism

50.0

Gene Expression

110.0

Mutagenesis

100.0

Case-Control Studies

60.0

DNA Repair/*genetics

5617.0

*Gene Expression Profiling

20.0

Proto-Oncogene Proteins/genetics/metabolism

73.0

RNA, Messenger/analysis

30.0

Reverse Transcriptase Polymerase Chain Reaction

110.0

Blotting, Northern

40.0

Cell Cycle

30.0

Cells, Cultured

80.0

Gene Library

30.0

Hela Cells

110.0

Models, Genetic

80.0

Oligonucleotide Array Sequence Analysis

40.0

Precipitin Tests

40.0

Promoter Regions (Genetics)

30.0

*Transcription, Genetic

30.0

Active Transport, Cell Nucleus

20.0

DNA-Binding Proteins/*metabolism

100.0

Phosphorylation

40.0

Protein-Serine-Threonine Kinases/metabolism

20.0

Proto-Oncogene Proteins/*metabolism

111.0

Neoplasm Proteins/analysis/*genetics

412.0

Proto-Oncogene Proteins/analysis/*genetics

48.0

DNA, Neoplasm/genetics

111.0

Germ-Line Mutation/*genetics

159.0

Neoplasm Proteins/*genetics

615.0

Pedigree

510.0

Polymerase Chain Reaction

430.0

Proto-Oncogene Proteins/*genetics

788.0

Follow-Up Studies

70.0

*Gene Expression Regulation, Neoplastic

60.0

Neoplasm Proteins/*biosynthesis/genetics

31.0

Neoplasm Staging

100.0

Prognosis

150.0

Survival Analysis

90.0

Chromatography, High Pressure Liquid/*methods

21.0

*DNA Mutational Analysis

31.0

Polymorphism, Genetic

60.0

Sequence Analysis, DNA

130.0

Time Factors

60.0

*Arabidopsis Proteins

22.0

Base Pair Mismatch/genetics

1840.0

Blotting, Southern

50.0

Phylogeny

20.0

Recombination, Genetic

60.0

Saccharomyces cerevisiae/genetics

51.0

Sequence Homology

20.0

Endometrial Neoplasms/*genetics/pathology

515.0

English Abstract

130.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*pathology

2100.0

Neoplasm Proteins/*analysis

41.0

Proto-Oncogene Proteins/*analysis/genetics

26.0

Colorectal Neoplasms/genetics

49.0

Colorectal Neoplasms, Hereditary Nonpolyposis/genetics

1944.0

DNA Repair/genetics

2917.0

*Gene Deletion

80.0

Adenoma/*pathology

29.0

Disease Progression

50.0

DNA/*genetics

20.0

DNA Transposable Elements

21.0

Dose-Response Relationship, Radiation

20.0

Genes, Dominant

20.0

Meiosis

32.0

*Proto-Oncogene Proteins

100.0

DNA-Binding Proteins/*genetics

442.0

Gene Expression Regulation, Neoplastic

100.0

*Gene Rearrangement

20.0

Gene Silencing

30.0

Point Mutation

110.0

Polymerase Chain Reaction/methods

60.0

Promoter Regions (Genetics)/genetics

30.0

B-Lymphocytes/immunology

20.0

DNA/genetics

70.0

*Immunoglobulin Class Switching

538.0

In Vitro

20.0

Mice, Knockout

180.0

Sequence Homology, Nucleic Acid

50.0

*Drosophila Proteins

20.0

DNA-Binding Proteins/genetics/*physiology

41.0

*Multidrug Resistance-Associated Proteins

1731.0

Binding Sites

50.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics/*metabolism

3100.0

Protein Binding

110.0

Adenosinetriphosphatase/metabolism

32.0

Mutation/*genetics

110.0

Neoplasm Proteins/*genetics/metabolism

85.0

DNA, Neoplasm/analysis

192.0

Immunoenzyme Techniques

130.0

Neoplasm Proteins/genetics/*metabolism

21.0

Sequence Analysis, DNA/methods

22.0

Colorectal Neoplasms/epidemiology/*genetics

215.0

Endometrial Neoplasms/epidemiology/*genetics

250.0

*Heterozygote

72.0

Variation (Genetics)/*genetics

20.0

Blotting, Western

40.0

Colorectal Neoplasms/*genetics/pathology

78.0

*Genetic Predisposition to Disease

161.0

*Mutation, Missense

61.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*genetics/*pathology

3100.0

DNA Replication/*genetics

23.0

Frameshift Mutation/genetics

22.0

Intestinal Mucosa/pathology

35.0

Skin Neoplasms/*genetics/pathology

35.0

DNA-Binding Proteins/genetics

161.0

Fungal Proteins/genetics

53.0

*Genes, Tumor Suppressor

30.0

Plasmids

20.0

Receptors, Transforming Growth Factor beta/genetics

23.0

*Saccharomyces cerevisiae Proteins

252.0

Proto-Oncogene Proteins/deficiency/genetics

360.0

Child

100.0

Rectal Neoplasms/*genetics/pathology

222.0

Syndrome

50.0

*Genetic Counseling

24.0

Prospective Studies

60.0

Stress, Psychological

27.0

*Acid Anhydride Hydrolases

52.0

Multivariate Analysis

50.0

Proto-Oncogene Proteins/*biosynthesis

85.0

Comparative Study

400.0

Retrospective Studies

40.0

*DNA Methylation

20.0

Age Factors

100.0

Child, Preschool

30.0

Colorectal Neoplasms, Hereditary Nonpolyposis/epidemiology/*genetics

675.0

Heterozygote

160.0

*Mutation

290.0

Netherlands/epidemiology

21.0

Registries

31.0

Risk Factors

170.0

Sex Factors

60.0

Fungal Proteins/*genetics

1310.0

Gene Deletion

110.0

Reproducibility of Results

20.0

*Trinucleotide Repeat Expansion

24.0

*Escherichia coli Proteins

31.0

Mice, Transgenic

60.0

*Mutagenesis

35.0

Repressor Proteins/genetics

21.0

Genes, APC

33.0

Genes, p53

61.0

Rectal Neoplasms/*genetics/metabolism/pathology

2100.0

Tumor Markers, Biological/metabolism

20.0

Genetic Predisposition to Disease

180.0

Genetic Screening

161.0

Incidence

100.0

Neoplasm Proteins/biosynthesis/genetics

75.0

Proto-Oncogene Proteins/biosynthesis/genetics

89.0

Analysis of Variance

20.0

Gene Frequency

30.0

Mutagenesis, Site-Directed

20.0

Saccharomyces cerevisiae/*genetics

127.0

Neoplasm Proteins/*metabolism

61.0

Loss of Heterozygosity

141.0

Antimetabolites, Antineoplastic/pharmacology

33.0

Doxorubicin/pharmacology

20.0

Ovarian Neoplasms/*genetics

30.0

Receptors, Transforming Growth Factor beta/*genetics

24.0

Exons/genetics

60.0

Ploidies

31.0

Fungal Proteins/*physiology

28.0

Ovarian Neoplasms/genetics

53.0

Risk Assessment

50.0

Carcinoma/*genetics/pathology

23.0

Neoplasm Proteins/*biosynthesis

44.0

Neoplasms, Multiple Primary/*genetics/pathology

220.0

Genetic Screening/methods

54.0

Breast Neoplasms/*genetics

30.0

DNA/chemistry/genetics

30.0

*Frameshift Mutation

52.0

Fatal Outcome

20.0

Germ-Line Mutation/genetics

57.0

Diagnosis, Differential

30.0

Genetic Predisposition to Disease/genetics

30.0

Netherlands

31.0

Penetrance

21.0

Colonic Neoplasms/*genetics/pathology

24.0

Genes, p53/genetics

31.0

Genes, ras/genetics

54.0

Statistics, Nonparametric

20.0

*Adenosinetriphosphatase

1824.0

Colonic Neoplasms/genetics

69.0

Endometrial Neoplasms/genetics

531.0

Rectal Neoplasms/genetics

222.0

Stomach Neoplasms/genetics

416.0

Urologic Neoplasms/genetics

2100.0

DNA Primers

80.0

DNA-Binding Proteins/physiology

20.0

*Gene Conversion

39.0

Repetitive Sequences, Nucleic Acid

40.0

Chromatography, High Pressure Liquid

40.0

Gene Frequency/genetics

30.0

Loss of Heterozygosity/genetics

32.0

Polymorphism, Genetic/genetics

20.0

United States

30.0

Dimerization

30.0

Tumor Markers, Biological/*biosynthesis

22.0

Adenomatous Polyposis Coli Protein

22.0

Polymorphism, Single-Stranded Conformational

140.0

Signal Transduction

20.0

Colorectal Neoplasms, Hereditary Nonpolyposis/genetics/pathology

457.0

*Loss of Heterozygosity

51.0

Gene Expression Profiling

30.0

DNA Mutational Analysis/methods

52.0

Sequence Analysis, RNA/*methods

240.0

*Sequence Deletion

30.0

Amino Acid Substitution

30.0

Cadherins/*biosynthesis

26.0

Cytoskeletal Proteins/*biosynthesis

211.0

*Immunohistochemistry

22.0

Neoplasm Metastasis

20.0

Linkage (Genetics)

90.0

Lymphatic Metastasis

50.0

Heteroduplex Analysis

22.0

*Recombination, Genetic

92.0

Proto-Oncogene Proteins/genetics/*metabolism

51.0

*DNA Damage

61.0

Protein Biosynthesis

50.0

Colorectal Neoplasms, Hereditary Nonpolyposis/diagnosis/*genetics

1191.0

Genetic Screening/*methods

42.0

Proto-Oncogene Proteins/analysis/genetics

621.0

DNA-Binding Proteins/biosynthesis/*genetics

32.0

Electrophoresis, Polyacrylamide Gel

20.0

In Situ Hybridization

30.0

Risk

20.0

Chromosomes, Human, Pair 2/genetics

42.0

Frameshift Mutation

71.0

Hybrid Cells

30.0

Mutagenesis, Insertional

31.0

Adenosinetriphosphatase/*genetics

33.0

Cloning, Molecular

90.0

DNA Helicases/*genetics

24.0

Ultraviolet Rays

50.0

Genetic Markers

80.0

Tumor Markers, Biological/analysis

40.0

Mutation, Missense/genetics

31.0

Dacarbazine/*analogs & derivatives/pharmacology

218.0

Drug Resistance, Neoplasm/*genetics

22.0

Colonic Neoplasms/*genetics

33.0

Mutation/genetics

90.0

*Polymorphism, Single Nucleotide

20.0

Protein-Serine-Threonine Kinases/genetics

21.0

Proteins/genetics

121.0

Variation (Genetics)

20.0

BRCA2 Protein

40.0

Transcription Factors/genetics

20.0

Consensus Sequence

20.0

Fungal Proteins/metabolism

42.0

Proliferating Cell Nuclear Antigen/*metabolism

21.0

Saccharomyces cerevisiae

41.0

Sequence Alignment

70.0

Neoplasm Invasiveness

30.0

Haplotypes

50.0

Transcription Factors/*genetics

20.0

Disease Models, Animal

20.0

History, 19th Century

310.0

History, 20th Century

32.0

DNA/analysis

20.0

DNA Primers/chemistry

40.0

Crosses, Genetic

40.0

Genes, Reporter

20.0

Mice, Inbred BALB C

40.0

Mutagenesis/*genetics

311.0

Proteins/genetics/*metabolism

40.0

Neoplastic Syndromes, Hereditary/genetics

26.0

Evolution, Molecular

20.0

*Founder Effect

54.0

Haplotypes/genetics

20.0

Introns

50.0

*Genes, Fungal

76.0

DNA, Neoplasm/*analysis

21.0

Finland/epidemiology

21.0

B-Lymphocytes/cytology/immunology

26.0

Cytidine Deaminase/metabolism

218.0

DNA-Binding Proteins/genetics/*metabolism

30.0

DNA-Directed DNA Polymerase/metabolism

39.0

*Somatic Hypermutation, Immunoglobulin

220.0

Herpesvirus 4, Human/genetics

22.0

DNA Methylation

40.0

DNA, Neoplasm/genetics/metabolism

22.0

Cell Cycle Proteins/metabolism

41.0

*Nuclear Proteins

20.0

Transcription, Genetic

20.0

Neoplasm Proteins/analysis/*biosynthesis

220.0

Proto-Oncogene Proteins/analysis/*biosynthesis

28.0

Colorectal Neoplasms/diagnosis/*genetics

333.0

Genome, Human

20.0

*Linkage Disequilibrium

21.0

DNA Primers/genetics

20.0

RNA, Messenger/biosynthesis

20.0

Mutation, Missense/*genetics

21.0

Fungal Proteins/*genetics/physiology

222.0

Aneuploidy

21.0

Cell Transformation, Neoplastic

20.0

Tumor Markers, Biological

20.0

DNA Repair/*physiology

21.0

Gene Expression Regulation, Developmental

20.0

Proto-Oncogene Proteins/*genetics/*metabolism

24.0

Bacterial Proteins/*genetics

23.0

DNA, Complementary/genetics

40.0

DNA-Binding Proteins/*biosynthesis

54.0

Meiosis/genetics

26.0

Rats

40.0

Electrophoresis, Gel, Two-Dimensional

30.0

Esophageal Neoplasms/*genetics

34.0

Polymorphism, Genetic/*genetics

20.0

*Sequence Homology, Nucleic Acid

22.0

Portugal

23.0

Chromosomes, Human, Pair 2/*genetics

31.0

In Situ Hybridization, Fluorescence

20.0

Tissue Distribution

20.0

Trinucleotide Repeats

21.0

Genetic Predisposition to Disease/*genetics

41.0

Great Britain/epidemiology

21.0

Survival Rate

50.0

DNA-Binding Proteins/analysis/genetics

211.0

Neoplasm Proteins/analysis/genetics

312.0

Genetic Markers/genetics

20.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis/genetics

2100.0

Genetic Techniques

22.0

*Genetic Screening

73.0

DNA, Satellite/genetics

21.0

Genetic Complementation Test

40.0

Neoplasm Proteins

39.0

Proteins/metabolism

20.0

*Disease Models, Animal

20.0

Cell Survival

30.0

Chromosome Mapping

70.0

Gene Amplification

20.0

Gene Expression Regulation

30.0

*Carrier Proteins

50.0

Flow Cytometry

20.0

Immunoglobulin Class Switching/*genetics

220.0

Colorectal Neoplasms, Hereditary Nonpolyposis/ethnology/*genetics

266.0

Proteins/*genetics

40.0

*Genes, p53

30.0

RNA, Messenger/genetics

30.0

Colon/*pathology

212.0

Italy/epidemiology

31.0

Colorectal Neoplasms/*genetics/metabolism

26.0

Gene Expression Regulation, Fungal

22.0

Methylation

40.0

*Promoter Regions (Genetics)

40.0

Hamsters

40.0

Founder Effect

21.0

Cell Differentiation

30.0

Codon

30.0

DNA Replication/genetics

35.0

Neoplasms/genetics

32.0

Yeasts/genetics

22.0

Antineoplastic Agents/pharmacology

30.0

Cisplatin/pharmacology

31.0

DNA-Binding Proteins/*physiology

20.0

Mass Screening

21.0

Frameshift Mutation/*genetics

23.0

Repetitive Sequences, Nucleic Acid/*genetics

21.0

Endometrial Neoplasms/complications/*genetics

266.0

Genetic Counseling

31.0

*Chromosome Mapping

30.0

Dose-Response Relationship, Drug

20.0

Protein p53/metabolism

30.0

CHO Cells

20.0

*Nucleic Acid Heteroduplexes

213.0

*Trinucleotide Repeats

21.0

DNA Replication

51.0

DNA-Binding Proteins

33.0

Genomic Instability

531.0

Genes, ras

41.0

*Neoplasm Proteins

40.0

Species Specificity

20.0

DNA, Neoplasm

21.0

DNA-Binding Proteins/*genetics/metabolism

81.0

Proto-Oncogene Proteins/*genetics/metabolism

53.0

RNA, Messenger/metabolism

30.0

Colorectal Neoplasms/*genetics/*pathology

28.0

Genes, Tumor Suppressor

30.0

Lymphoma/*genetics

24.0

Proto-Oncogene Proteins c-bcl-2/genetics

21.0

Statistics

20.0

*Gene Expression Regulation, Developmental

20.0

Adenosine Triphosphate/*metabolism

22.0

Hydrolysis

20.0

Oligonucleotide Probes/genetics

21.0

Codon/genetics

20.0

DNA-Binding Proteins/deficiency/genetics

313.0

Disease Susceptibility

50.0

*Chromosomes, Human, Pair 2

31.0

Proto-Oncogene Proteins/*physiology

31.0

*Polymorphism, Genetic

50.0

Transfection

30.0

Probability

30.0

*Fungal Proteins

720.0

*Schizosaccharomyces pombe Proteins

22.0

Nucleic Acid Heteroduplexes

36.0

Substrate Specificity

20.0

Nucleic Acid Heteroduplexes/*genetics

215.0

Fungal Proteins/*metabolism

33.0

Models, Molecular

20.0

Lymphoma, Lymphoblastic/*genetics/pathology

2100.0

Chromosomes, Human, Pair 2

42.0

RNA-Directed DNA Polymerase

21.0

DNA, Complementary

20.0

Genes, Fungal

21.0

Recombinant Proteins/genetics/metabolism

20.0

DNA/metabolism

20.0

Protein p53/genetics/*metabolism

21.0

Mitosis

20.0

DNA-Binding Proteins/*analysis

23.0

Proto-Oncogene Proteins/*analysis

21.0

*Repetitive Sequences, Nucleic Acid

41.0

Cell Transformation, Neoplastic/genetics

20.0

*Genes, APC

22.0

Cohort Studies

70.0

Gene Expression Regulation, Neoplastic/genetics

21.0

*Caenorhabditis elegans Proteins

54.0

Colonoscopy

24.0

Protein p53/genetics

31.0

Family

30.0

*Homozygote

21.0

Proto-Oncogene Proteins/deficiency/genetics/*metabolism

222.0

*DNA Repair/drug effects

240.0

Kinetics

20.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*diagnosis

2100.0

Finland

20.0

Sex Distribution

31.0

Cost-Benefit Analysis

43.0

Carcinoma/*genetics

21.0

Adenosinetriphosphatase/*genetics/metabolism

27.0

Mass Screening/methods

24.0

Nuclear Proteins/metabolism

20.0

Age Distribution

20.0

Genetic Predisposition to Disease/*ethnology

216.0

Jews/*genetics

42.0

United States/epidemiology

20.0

Protein Structure, Tertiary

20.0

Protein p53/biosynthesis

21.0

Colorectal Neoplasms, Hereditary Nonpolyposis/*epidemiology/*genetics

266.0

Heterozygote Detection

30.0