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Taipei Medical University

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Gene Symbol
Gene NameAliasesPrevious_Symbol

MMP2

matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)TBE-1matrix metalloproteinase 2 (gelatinase A, 72kD gelatinase, 72kD type IV collagenase)


Gene MMP2 gene interaction
View Neighborhood Gene

Result number fewer <<<< << < ALL > >> >>> more

MeSH term
FrequencyCondition_Probility

Humans

1560.0

Aged

250.0

Time Factors

70.0

Adult

310.0

Female

590.0

Immunohistochemistry

280.0

Male

350.0

Middle Aged

320.0

Prognosis

200.0

Survival Rate

80.0

Gelatinase A/genetics

216.0

*Gene Expression Regulation, Neoplastic

40.0

RNA, Messenger/analysis

100.0

Research Support, Non-U.S. Gov't

970.0

Transforming Growth Factor beta/*physiology

21.0

Binding Sites

60.0

Catalytic Domain

41.0

Crystallography, X-Ray

40.0

Electrophoresis, Polyacrylamide Gel

40.0

Models, Molecular

40.0

Protein Binding

70.0

Protein Structure, Secondary

30.0

Protein Structure, Tertiary

60.0

Research Support, U.S. Gov't, Non-P.H.S.

60.0

Animals

430.0

*Gene Expression Profiling

20.0

Genetic Markers

20.0

Mice

280.0

Mice, Inbred C57BL

30.0

Research Support, U.S. Gov't, P.H.S.

290.0

Protein Conformation

30.0

Comparative Study

230.0

DNA, Complementary/isolation & purification

21.0

Matrix Metalloproteinases/genetics/*metabolism

225.0

Polymerase Chain Reaction

40.0

Tissue Inhibitor of Metalloproteinases/genetics/*metabolism

233.0

Cytokines/genetics

21.0

Mice, Inbred BALB C

60.0

Mice, Knockout

30.0

Protease Inhibitors/pharmacology

62.0

Up-Regulation

40.0

Blotting, Northern

70.0

Blotting, Western

100.0

English Abstract

110.0

Gelatinase A/*genetics/metabolism

266.0

Gene Expression Regulation, Enzymologic

20.0

Gene Expression Regulation, Neoplastic

40.0

RNA, Messenger/genetics/metabolism

50.0

Tumor Cells, Cultured

240.0

Chick Embryo

20.0

Disease Progression

40.0

Gelatinase B/biosynthesis

314.0

Aged, 80 and over

50.0

Gelatinase A/genetics/*metabolism

225.0

In Situ Hybridization

90.0

Metalloendopeptidases/genetics/*metabolism

411.0

Metalloendopeptidases/genetics/metabolism

240.0

Tissue Inhibitor of Metalloproteinase-1/genetics/metabolism

215.0

Tissue Inhibitor of Metalloproteinase-2/genetics/metabolism

218.0

Apoptosis

20.0

DNA Primers/chemistry

40.0

Enzyme-Linked Immunosorbent Assay

50.0

Gene Transfer Techniques

20.0

Mice, Nude

80.0

Neoplasm Invasiveness

171.0

Tissue Inhibitor of Metalloproteinase-1/*genetics

212.0

Amino Acid Sequence

120.0

COS Cells

20.0

Cell Membrane/enzymology

20.0

Enzyme Activation

150.0

Enzyme Induction

40.0

Enzyme Precursors/metabolism

32.0

Models, Biological

30.0

Molecular Sequence Data

150.0

Neoplasm Invasiveness/*physiopathology

316.0

Sequence Alignment

20.0

Sequence Homology, Amino Acid

40.0

Structure-Activity Relationship

20.0

Substrate Specificity

40.0

Cell Differentiation/physiology

20.0

Cell Movement/physiology

20.0

Cells, Cultured

240.0

Gelatinase A/*biosynthesis

444.0

Gelatinase B/*biosynthesis

214.0

Survival Analysis

30.0

Tissue Inhibitor of Metalloproteinase-1/biosynthesis

213.0

Extracellular Matrix Proteins/metabolism

33.0

Hydrolysis

20.0

Protease Inhibitors/*pharmacology

36.0

Models, Chemical

30.0

Solubility

60.0

Gelatinase A/*metabolism

1339.0

Gelatinase B/*metabolism

721.0

Protein Binding/physiology

20.0

Enzyme Activation/drug effects

90.0

Extracellular Matrix/*metabolism

33.0

Gelatinase A/genetics/metabolism

222.0

Neoplasm Recurrence, Local

20.0

Tissue Inhibitor of Metalloproteinase-2/genetics

233.0

Gelatinase A/*genetics

222.0

Fetal Membranes, Premature Rupture/*metabolism

250.0

Gelatinase A/metabolism

915.0

Gelatinase B/metabolism

47.0

Pregnancy

50.0

Tissue Inhibitor of Metalloproteinase-2/metabolism

627.0

Matrix Metalloproteinases/*analysis

342.0

Tissue Inhibitor of Metalloproteinases/*analysis

2100.0

Gels

22.0

Skin/cytology

21.0

Cell Division

80.0

Immunoenzyme Techniques

40.0

Dose-Response Relationship, Drug

50.0

Enzyme Inhibitors/pharmacology

60.0

Metalloendopeptidases/biosynthesis/genetics

342.0

Phosphorylation/drug effects

20.0

Protein-Tyrosine Kinase/metabolism

40.0

RNA, Messenger/biosynthesis/genetics

30.0

Tissue Inhibitor of Metalloproteinase-2/biosynthesis/genetics

337.0

Tyrosine/metabolism

20.0

Gelatinase A/biosynthesis

531.0

Matrix Metalloproteinases/*biosynthesis

327.0

Rats

80.0

Rats, Wistar

20.0

Recombinant Proteins/pharmacology

30.0

Reverse Transcriptase Polymerase Chain Reaction

100.0

Statistics, Nonparametric

20.0

DNA, Complementary/genetics

20.0

Fibroblasts/metabolism

30.0

Oligonucleotide Array Sequence Analysis

50.0

Gelatinase B/genetics/*metabolism

228.0

RNA, Messenger/metabolism

70.0

Tissue Distribution

20.0

Adolescent

40.0

Child

30.0

Child, Preschool

30.0

Disease-Free Survival

20.0

Retrospective Studies

20.0

Tumor Markers, Biological/*analysis

20.0

Gelatinase A/analysis

218.0

Gelatinase B/analysis

211.0

Neoplasm Staging

60.0

Collagen/*metabolism

21.0

Base Sequence

70.0

Cattle

20.0

DNA Primers/genetics

20.0

Gelatinase A/biosynthesis/genetics

325.0

Glomerular Mesangium/cytology/*enzymology

250.0

Gene Expression Regulation

30.0

Down-Regulation

20.0

Gene Expression Profiling

30.0

In Vitro

50.0

Phenylalanine/analogs & derivatives/pharmacology

342.0

RNA, Messenger/genetics

40.0

Thiophenes/pharmacology

513.0

Tissue Inhibitor of Metalloproteinase-2/*metabolism

240.0

Biopsy

60.0

Liver Neoplasms/secondary

23.0

Matrix Metalloproteinases/metabolism

24.0

Gelatinase A/*chemistry

2100.0

Microscopy, Electron

30.0

Antibodies, Monoclonal/*metabolism

25.0

Cell Line, Tumor

70.0

Metalloendopeptidases/metabolism

58.0

Phosphorylation

40.0

Precipitin Tests

40.0

Cathepsins/*metabolism

212.0

Collagen/*chemistry/metabolism

266.0

Neovascularization, Pathologic

20.0

Phenylalanine/*analogs & derivatives/pharmacology

316.0

Transcription, Genetic

20.0

Cell Line

30.0

Collagenases/metabolism

514.0

Collagen/*chemistry

220.0

Extracellular Matrix/metabolism

31.0

Kinetics

20.0

Gelatinase A/antagonists & inhibitors/metabolism

250.0

Metalloendopeptidases/*antagonists & inhibitors/metabolism

240.0

Glucose/pharmacology

21.0

Antineoplastic Agents/*pharmacology

30.0

Tumor Cells, Cultured/drug effects

20.0

RNA, Messenger/*metabolism

30.0

Gene Expression

60.0

Cell Survival/drug effects

30.0

*Cell Movement

21.0

Phenotype

40.0

Swine

30.0

Gelatinase A

3548.0

Interstitial Collagenase

819.0

Vascular Endothelial Growth Factor A

30.0

Vascular Endothelial Growth Factors

30.0

Gelatinases/*genetics

233.0

Metalloendopeptidases/*genetics

22.0

Neoplasm Metastasis

50.0

Transfection

50.0

Gelatin/metabolism

214.0

Rabbits

20.0

Cycloheximide/pharmacology

20.0

Dactinomycin/pharmacology

20.0

Gelatinases/*metabolism

937.0

Metalloendopeptidases/*analysis/immunology

2100.0

*Neoplasm Invasiveness

22.0

Metalloendopeptidases/*metabolism

77.0

Chronic Disease

20.0

Gelatinase B

1620.0

Gelatinases/metabolism

515.0

Infant, Newborn

20.0

Metalloendopeptidases/*biosynthesis

314.0

Cell Membrane/metabolism

30.0

Culture Media, Conditioned/metabolism

26.0

Flow Cytometry

20.0

Signal Transduction

30.0

Collagenases/*metabolism

414.0

Tetradecanoylphorbol Acetate/pharmacology

20.0

Cell Line, Transformed

20.0

Case-Control Studies

30.0

Tissue Inhibitor of Metalloproteinase-2

828.0

Tissue Inhibitor of Metalloproteinases

914.0

Umbilical Veins

20.0

Interstitial Collagenase/biosynthesis

233.0

DNA Primers

20.0

*Protein Biosynthesis

20.0

Stromal Cells/metabolism/pathology

24.0

Epithelial Cells

30.0

Metalloendopeptidases/antagonists & inhibitors/*metabolism

211.0

Recombinant Fusion Proteins/metabolism

30.0

Culture Media, Conditioned

30.0

Matrix Metalloproteinases/*metabolism

37.0

Glycoproteins/pharmacology

25.0

Organ Culture Techniques

20.0

Neoplasm Proteins/*metabolism

20.0

Tissue Inhibitor of Metalloproteinase-2/*biosynthesis

2100.0

Culture Media, Conditioned/pharmacology

21.0

Protease Inhibitors/metabolism

26.0

Stromelysin 1

37.0

Cell Movement/drug effects

41.0

Neoplasm Transplantation

30.0

Collagen

21.0

Tumor Markers, Biological/*biosynthesis

22.0

Multivariate Analysis

30.0

Proportional Hazards Models

20.0

Fibroblasts/enzymology

21.0

Transcription, Genetic/drug effects

20.0

Basement Membrane/pathology

25.0

Cell Movement

30.0

Breast Neoplasms/*enzymology

23.0

Extracellular Matrix/*enzymology

215.0

Polymorphism, Genetic

20.0