MeSH term
Frequency | Condition_Probility | Humans | 156 | 0.0 |
Aged | 25 | 0.0 |
Time Factors | 7 | 0.0 |
Adult | 31 | 0.0 |
Female | 59 | 0.0 |
Immunohistochemistry | 28 | 0.0 |
Male | 35 | 0.0 |
Middle Aged | 32 | 0.0 |
Prognosis | 20 | 0.0 |
Survival Rate | 8 | 0.0 |
Gelatinase A/genetics | 2 | 16.0 |
*Gene Expression Regulation, Neoplastic | 4 | 0.0 |
RNA, Messenger/analysis | 10 | 0.0 |
Research Support, Non-U.S. Gov't | 97 | 0.0 |
Transforming Growth Factor beta/*physiology | 2 | 1.0 |
Binding Sites | 6 | 0.0 |
Catalytic Domain | 4 | 1.0 |
Crystallography, X-Ray | 4 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 4 | 0.0 |
Models, Molecular | 4 | 0.0 |
Protein Binding | 7 | 0.0 |
Protein Structure, Secondary | 3 | 0.0 |
Protein Structure, Tertiary | 6 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 6 | 0.0 |
Animals | 43 | 0.0 |
*Gene Expression Profiling | 2 | 0.0 |
Genetic Markers | 2 | 0.0 |
Mice | 28 | 0.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 29 | 0.0 |
Protein Conformation | 3 | 0.0 |
Comparative Study | 23 | 0.0 |
DNA, Complementary/isolation & purification | 2 | 1.0 |
Matrix Metalloproteinases/genetics/*metabolism | 2 | 25.0 |
Polymerase Chain Reaction | 4 | 0.0 |
Tissue Inhibitor of Metalloproteinases/genetics/*metabolism | 2 | 33.0 |
Cytokines/genetics | 2 | 1.0 |
Mice, Inbred BALB C | 6 | 0.0 |
Mice, Knockout | 3 | 0.0 |
Protease Inhibitors/pharmacology | 6 | 2.0 |
Up-Regulation | 4 | 0.0 |
Blotting, Northern | 7 | 0.0 |
Blotting, Western | 10 | 0.0 |
English Abstract | 11 | 0.0 |
Gelatinase A/*genetics/metabolism | 2 | 66.0 |
Gene Expression Regulation, Enzymologic | 2 | 0.0 |
Gene Expression Regulation, Neoplastic | 4 | 0.0 |
RNA, Messenger/genetics/metabolism | 5 | 0.0 |
Tumor Cells, Cultured | 24 | 0.0 |
Chick Embryo | 2 | 0.0 |
Disease Progression | 4 | 0.0 |
Gelatinase B/biosynthesis | 3 | 14.0 |
Aged, 80 and over | 5 | 0.0 |
Gelatinase A/genetics/*metabolism | 2 | 25.0 |
In Situ Hybridization | 9 | 0.0 |
Metalloendopeptidases/genetics/*metabolism | 4 | 11.0 |
Metalloendopeptidases/genetics/metabolism | 2 | 40.0 |
Tissue Inhibitor of Metalloproteinase-1/genetics/metabolism | 2 | 15.0 |
Tissue Inhibitor of Metalloproteinase-2/genetics/metabolism | 2 | 18.0 |
Apoptosis | 2 | 0.0 |
DNA Primers/chemistry | 4 | 0.0 |
Enzyme-Linked Immunosorbent Assay | 5 | 0.0 |
Gene Transfer Techniques | 2 | 0.0 |
Mice, Nude | 8 | 0.0 |
Neoplasm Invasiveness | 17 | 1.0 |
Tissue Inhibitor of Metalloproteinase-1/*genetics | 2 | 12.0 |
Amino Acid Sequence | 12 | 0.0 |
COS Cells | 2 | 0.0 |
Cell Membrane/enzymology | 2 | 0.0 |
Enzyme Activation | 15 | 0.0 |
Enzyme Induction | 4 | 0.0 |
Enzyme Precursors/metabolism | 3 | 2.0 |
Models, Biological | 3 | 0.0 |
Molecular Sequence Data | 15 | 0.0 |
Neoplasm Invasiveness/*physiopathology | 3 | 16.0 |
Sequence Alignment | 2 | 0.0 |
Sequence Homology, Amino Acid | 4 | 0.0 |
Structure-Activity Relationship | 2 | 0.0 |
Substrate Specificity | 4 | 0.0 |
Cell Differentiation/physiology | 2 | 0.0 |
Cell Movement/physiology | 2 | 0.0 |
Cells, Cultured | 24 | 0.0 |
Gelatinase A/*biosynthesis | 4 | 44.0 |
Gelatinase B/*biosynthesis | 2 | 14.0 |
Survival Analysis | 3 | 0.0 |
Tissue Inhibitor of Metalloproteinase-1/biosynthesis | 2 | 13.0 |
Extracellular Matrix Proteins/metabolism | 3 | 3.0 |
Hydrolysis | 2 | 0.0 |
Protease Inhibitors/*pharmacology | 3 | 6.0 |
Models, Chemical | 3 | 0.0 |
Solubility | 6 | 0.0 |
Gelatinase A/*metabolism | 13 | 39.0 |
Gelatinase B/*metabolism | 7 | 21.0 |
Protein Binding/physiology | 2 | 0.0 |
Enzyme Activation/drug effects | 9 | 0.0 |
Extracellular Matrix/*metabolism | 3 | 3.0 |
Gelatinase A/genetics/metabolism | 2 | 22.0 |
Neoplasm Recurrence, Local | 2 | 0.0 |
Tissue Inhibitor of Metalloproteinase-2/genetics | 2 | 33.0 |
Gelatinase A/*genetics | 2 | 22.0 |
Fetal Membranes, Premature Rupture/*metabolism | 2 | 50.0 |
Gelatinase A/metabolism | 9 | 15.0 |
Gelatinase B/metabolism | 4 | 7.0 |
Pregnancy | 5 | 0.0 |
Tissue Inhibitor of Metalloproteinase-2/metabolism | 6 | 27.0 |
Matrix Metalloproteinases/*analysis | 3 | 42.0 |
Tissue Inhibitor of Metalloproteinases/*analysis | 2 | 100.0 |
Gels | 2 | 2.0 |
Skin/cytology | 2 | 1.0 |
Cell Division | 8 | 0.0 |
Immunoenzyme Techniques | 4 | 0.0 |
Dose-Response Relationship, Drug | 5 | 0.0 |
Enzyme Inhibitors/pharmacology | 6 | 0.0 |
Metalloendopeptidases/biosynthesis/genetics | 3 | 42.0 |
Phosphorylation/drug effects | 2 | 0.0 |
Protein-Tyrosine Kinase/metabolism | 4 | 0.0 |
RNA, Messenger/biosynthesis/genetics | 3 | 0.0 |
Tissue Inhibitor of Metalloproteinase-2/biosynthesis/genetics | 3 | 37.0 |
Tyrosine/metabolism | 2 | 0.0 |
Gelatinase A/biosynthesis | 5 | 31.0 |
Matrix Metalloproteinases/*biosynthesis | 3 | 27.0 |
Rats | 8 | 0.0 |
Rats, Wistar | 2 | 0.0 |
Recombinant Proteins/pharmacology | 3 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 10 | 0.0 |
Statistics, Nonparametric | 2 | 0.0 |
DNA, Complementary/genetics | 2 | 0.0 |
Fibroblasts/metabolism | 3 | 0.0 |
Oligonucleotide Array Sequence Analysis | 5 | 0.0 |
Gelatinase B/genetics/*metabolism | 2 | 28.0 |
RNA, Messenger/metabolism | 7 | 0.0 |
Tissue Distribution | 2 | 0.0 |
Adolescent | 4 | 0.0 |
Child | 3 | 0.0 |
Child, Preschool | 3 | 0.0 |
Disease-Free Survival | 2 | 0.0 |
Retrospective Studies | 2 | 0.0 |
Tumor Markers, Biological/*analysis | 2 | 0.0 |
Gelatinase A/analysis | 2 | 18.0 |
Gelatinase B/analysis | 2 | 11.0 |
Neoplasm Staging | 6 | 0.0 |
Collagen/*metabolism | 2 | 1.0 |
Base Sequence | 7 | 0.0 |
Cattle | 2 | 0.0 |
DNA Primers/genetics | 2 | 0.0 |
Gelatinase A/biosynthesis/genetics | 3 | 25.0 |
Glomerular Mesangium/cytology/*enzymology | 2 | 50.0 |
Gene Expression Regulation | 3 | 0.0 |
Down-Regulation | 2 | 0.0 |
Gene Expression Profiling | 3 | 0.0 |
In Vitro | 5 | 0.0 |
Phenylalanine/analogs & derivatives/pharmacology | 3 | 42.0 |
RNA, Messenger/genetics | 4 | 0.0 |
Thiophenes/pharmacology | 5 | 13.0 |
Tissue Inhibitor of Metalloproteinase-2/*metabolism | 2 | 40.0 |
Biopsy | 6 | 0.0 |
Liver Neoplasms/secondary | 2 | 3.0 |
Matrix Metalloproteinases/metabolism | 2 | 4.0 |
Gelatinase A/*chemistry | 2 | 100.0 |
Microscopy, Electron | 3 | 0.0 |
Antibodies, Monoclonal/*metabolism | 2 | 5.0 |
Cell Line, Tumor | 7 | 0.0 |
Metalloendopeptidases/metabolism | 5 | 8.0 |
Phosphorylation | 4 | 0.0 |
Precipitin Tests | 4 | 0.0 |
Cathepsins/*metabolism | 2 | 12.0 |
Collagen/*chemistry/metabolism | 2 | 66.0 |
Neovascularization, Pathologic | 2 | 0.0 |
Phenylalanine/*analogs & derivatives/pharmacology | 3 | 16.0 |
Transcription, Genetic | 2 | 0.0 |
Cell Line | 3 | 0.0 |
Collagenases/metabolism | 5 | 14.0 |
Collagen/*chemistry | 2 | 20.0 |
Extracellular Matrix/metabolism | 3 | 1.0 |
Kinetics | 2 | 0.0 |
Gelatinase A/antagonists & inhibitors/metabolism | 2 | 50.0 |
Metalloendopeptidases/*antagonists & inhibitors/metabolism | 2 | 40.0 |
Glucose/pharmacology | 2 | 1.0 |
Antineoplastic Agents/*pharmacology | 3 | 0.0 |
Tumor Cells, Cultured/drug effects | 2 | 0.0 |
RNA, Messenger/*metabolism | 3 | 0.0 |
Gene Expression | 6 | 0.0 |
Cell Survival/drug effects | 3 | 0.0 |
*Cell Movement | 2 | 1.0 |
Phenotype | 4 | 0.0 |
Swine | 3 | 0.0 |
Gelatinase A | 35 | 48.0 |
Interstitial Collagenase | 8 | 19.0 |
Vascular Endothelial Growth Factor A | 3 | 0.0 |
Vascular Endothelial Growth Factors | 3 | 0.0 |
Gelatinases/*genetics | 2 | 33.0 |
Metalloendopeptidases/*genetics | 2 | 2.0 |
Neoplasm Metastasis | 5 | 0.0 |
Transfection | 5 | 0.0 |
Gelatin/metabolism | 2 | 14.0 |
Rabbits | 2 | 0.0 |
Cycloheximide/pharmacology | 2 | 0.0 |
Dactinomycin/pharmacology | 2 | 0.0 |
Gelatinases/*metabolism | 9 | 37.0 |
Metalloendopeptidases/*analysis/immunology | 2 | 100.0 |
*Neoplasm Invasiveness | 2 | 2.0 |
Metalloendopeptidases/*metabolism | 7 | 7.0 |
Chronic Disease | 2 | 0.0 |
Gelatinase B | 16 | 20.0 |
Gelatinases/metabolism | 5 | 15.0 |
Infant, Newborn | 2 | 0.0 |
Metalloendopeptidases/*biosynthesis | 3 | 14.0 |
Cell Membrane/metabolism | 3 | 0.0 |
Culture Media, Conditioned/metabolism | 2 | 6.0 |
Flow Cytometry | 2 | 0.0 |
Signal Transduction | 3 | 0.0 |
Collagenases/*metabolism | 4 | 14.0 |
Tetradecanoylphorbol Acetate/pharmacology | 2 | 0.0 |
Cell Line, Transformed | 2 | 0.0 |
Case-Control Studies | 3 | 0.0 |
Tissue Inhibitor of Metalloproteinase-2 | 8 | 28.0 |
Tissue Inhibitor of Metalloproteinases | 9 | 14.0 |
Umbilical Veins | 2 | 0.0 |
Interstitial Collagenase/biosynthesis | 2 | 33.0 |
DNA Primers | 2 | 0.0 |
*Protein Biosynthesis | 2 | 0.0 |
Stromal Cells/metabolism/pathology | 2 | 4.0 |
Epithelial Cells | 3 | 0.0 |
Metalloendopeptidases/antagonists & inhibitors/*metabolism | 2 | 11.0 |
Recombinant Fusion Proteins/metabolism | 3 | 0.0 |
Culture Media, Conditioned | 3 | 0.0 |
Matrix Metalloproteinases/*metabolism | 3 | 7.0 |
Glycoproteins/pharmacology | 2 | 5.0 |
Organ Culture Techniques | 2 | 0.0 |
Neoplasm Proteins/*metabolism | 2 | 0.0 |
Tissue Inhibitor of Metalloproteinase-2/*biosynthesis | 2 | 100.0 |
Culture Media, Conditioned/pharmacology | 2 | 1.0 |
Protease Inhibitors/metabolism | 2 | 6.0 |
Stromelysin 1 | 3 | 7.0 |
Cell Movement/drug effects | 4 | 1.0 |
Neoplasm Transplantation | 3 | 0.0 |
Collagen | 2 | 1.0 |
Tumor Markers, Biological/*biosynthesis | 2 | 2.0 |
Multivariate Analysis | 3 | 0.0 |
Proportional Hazards Models | 2 | 0.0 |
Fibroblasts/enzymology | 2 | 1.0 |
Transcription, Genetic/drug effects | 2 | 0.0 |
Basement Membrane/pathology | 2 | 5.0 |
Cell Movement | 3 | 0.0 |
Breast Neoplasms/*enzymology | 2 | 3.0 |
Extracellular Matrix/*enzymology | 2 | 15.0 |
Polymorphism, Genetic | 2 | 0.0 |