MeSH term
Frequency | Condition_Probility | Humans | 113 | 0.0 |
Animals | 71 | 0.0 |
English Abstract | 3 | 0.0 |
Gene Frequency | 6 | 0.0 |
Genetic Screening | 2 | 0.0 |
Genotype | 7 | 0.0 |
Polymorphism, Restriction Fragment Length | 7 | 0.0 |
Receptor, Melanocortin, Type 4 | 55 | 82.0 |
Receptors, Peptide/*genetics | 7 | 31.0 |
Research Support, Non-U.S. Gov't | 75 | 0.0 |
Amino Acid Substitution | 6 | 0.0 |
Cell Line | 30 | 0.0 |
Mice | 32 | 0.0 |
Oligopeptides/*chemical synthesis/chemistry/pharmacology | 3 | 75.0 |
Receptor, Melanocortin, Type 3 | 19 | 70.0 |
Receptors, Corticotropin/agonists/antagonists & inhibitors/*drug effects | 2 | 100.0 |
Receptors, Melanocortin | 17 | 17.0 |
Research Support, U.S. Gov't, P.H.S. | 44 | 0.0 |
Structure-Activity Relationship | 24 | 0.0 |
Body Weight | 5 | 0.0 |
*Energy Metabolism | 2 | 2.0 |
Female | 32 | 0.0 |
Male | 36 | 0.0 |
Combinatorial Chemistry Techniques | 2 | 10.0 |
Magnetic Resonance Spectroscopy | 7 | 1.0 |
alpha-MSH/*chemistry | 2 | 100.0 |
Amino Acid Sequence | 32 | 0.0 |
Binding, Competitive | 11 | 0.0 |
Molecular Sequence Data | 32 | 0.0 |
Protein Folding | 3 | 0.0 |
Protein Structure, Tertiary | 5 | 0.0 |
Base Sequence | 8 | 0.0 |
Binding Sites | 6 | 0.0 |
Chimeric Proteins/metabolism | 2 | 1.0 |
DNA Primers | 4 | 0.0 |
Genes, Reporter | 3 | 0.0 |
Kinetics | 5 | 0.0 |
MSH/metabolism | 2 | 33.0 |
Models, Molecular | 16 | 0.0 |
Protein Conformation | 9 | 0.0 |
Rats | 8 | 0.0 |
Sequence Alignment | 6 | 0.0 |
Sequence Homology, Amino Acid | 6 | 0.0 |
Substrate Specificity | 2 | 0.0 |
Adult | 22 | 0.0 |
Arizona | 2 | 6.0 |
Body Mass Index | 8 | 0.0 |
Codon/genetics | 3 | 0.0 |
Heterozygote Detection | 2 | 0.0 |
Obesity/*genetics | 15 | 12.0 |
Pedigree | 13 | 0.0 |
Receptor, Melanocortin, Type 4/*genetics | 6 | 85.0 |
Reference Values | 2 | 0.0 |
Adolescent | 15 | 0.0 |
Child | 12 | 0.0 |
Child, Preschool | 6 | 0.0 |
Chromatography, High Pressure Liquid | 2 | 0.0 |
*Mutation | 16 | 0.0 |
Mutation, Missense | 3 | 0.0 |
Polymorphism, Genetic | 4 | 0.0 |
Polymorphism, Single-Stranded Conformational | 4 | 0.0 |
Sequence Analysis, DNA | 2 | 0.0 |
Mutation | 7 | 0.0 |
Pro-Opiomelanocortin/genetics/*metabolism | 2 | 50.0 |
Signal Transduction/*physiology | 4 | 0.0 |
*Intercellular Signaling Peptides and Proteins | 2 | 0.0 |
*Receptor, Melanocortin, Type 3 | 5 | 71.0 |
Receptors, Corticotropin/metabolism | 3 | 50.0 |
Aged | 7 | 0.0 |
Alleles | 4 | 0.0 |
Blood Glucose/metabolism | 2 | 0.0 |
Homozygote | 2 | 0.0 |
Japan | 2 | 0.0 |
Leptin/blood | 2 | 3.0 |
Obesity, Morbid/*genetics | 3 | 27.0 |
Recombinant Proteins/metabolism | 2 | 0.0 |
Transfection | 13 | 0.0 |
alpha-MSH/pharmacology | 4 | 33.0 |
Amino Acid Motifs | 3 | 0.0 |
Protein Structure, Secondary | 10 | 0.0 |
CHO Cells | 6 | 0.0 |
Hamsters | 6 | 0.0 |
Receptor, Melanocortin, Type 4/*agonists/metabolism | 2 | 100.0 |
Cloning, Molecular | 4 | 0.0 |
DNA Mutational Analysis | 3 | 0.0 |
Receptors, Corticotropin/chemistry/*genetics | 2 | 66.0 |
Case-Control Studies | 8 | 0.0 |
*DNA Mutational Analysis | 2 | 1.0 |
Polymerase Chain Reaction | 5 | 0.0 |
Proteins/*genetics | 3 | 0.0 |
Diagnosis, Differential | 2 | 0.0 |
Primary Prevention | 2 | 16.0 |
Risk Factors | 2 | 0.0 |
Heterozygote | 6 | 0.0 |
Insulin/blood | 3 | 0.0 |
Middle Aged | 15 | 0.0 |
Obesity | 2 | 3.0 |
Receptors, Corticotropin/*genetics | 9 | 18.0 |
Cells, Cultured | 4 | 0.0 |
Ligands | 15 | 0.0 |
Base Sequence/genetics | 3 | 0.0 |
Linkage Disequilibrium | 3 | 0.0 |
Variation (Genetics) | 3 | 0.0 |
Molecular Structure | 3 | 0.0 |
Protein Binding | 9 | 0.0 |
Radioligand Assay | 5 | 1.0 |
Receptors, Melanocortin/*agonists | 2 | 100.0 |
Eating/drug effects | 2 | 5.0 |
Injections, Intraventricular | 2 | 1.0 |
Peptide Fragments/*pharmacology | 2 | 1.0 |
Species Specificity | 2 | 0.0 |
Fasting | 2 | 0.0 |
Finland | 2 | 0.0 |
*Polymorphism, Genetic | 2 | 0.0 |
DNA Primers/genetics | 2 | 0.0 |
*Gene Expression Regulation | 2 | 0.0 |
Time Factors | 4 | 0.0 |
Cyclic AMP/metabolism | 11 | 2.0 |
L Cells (Cell Line) | 2 | 0.0 |
Receptors, Corticotropin/*metabolism | 2 | 22.0 |
Adenylate Cyclase/metabolism | 3 | 2.0 |
Forskolin/pharmacology | 2 | 0.0 |
Age Factors | 2 | 0.0 |
Feeding Behavior | 3 | 13.0 |
Hyperinsulinism/genetics | 2 | 25.0 |
In Situ Hybridization | 3 | 0.0 |
Mice, Knockout | 3 | 0.0 |
Models, Genetic | 2 | 0.0 |
Obesity/genetics | 2 | 3.0 |
Phenotype | 8 | 0.0 |
Receptors, Peptide/genetics/metabolism | 3 | 25.0 |
Tissue Distribution | 4 | 0.0 |
Age of Onset | 5 | 0.0 |
Body Composition | 3 | 1.0 |
Energy Metabolism | 4 | 2.0 |
Genes, Dominant | 2 | 0.0 |
Receptors, Corticotropin/*agonists | 2 | 100.0 |
Infant | 2 | 0.0 |
Body Weight/*genetics | 2 | 13.0 |
Quebec | 2 | 3.0 |
Receptors, Corticotropin/genetics | 2 | 16.0 |
COS Cells | 6 | 0.0 |
Cell Membrane/metabolism | 2 | 0.0 |
Frameshift Mutation | 2 | 0.0 |
Chickens/*genetics | 2 | 2.0 |
Comparative Study | 7 | 0.0 |
Leptin/*blood | 2 | 2.0 |
Dose-Response Relationship, Drug | 4 | 0.0 |
Receptors, Corticotropin/genetics/metabolism | 2 | 100.0 |
Signal Transduction | 4 | 0.0 |
Hypothalamus/metabolism | 2 | 4.0 |
Leptin | 2 | 1.0 |
Mice, Transgenic | 4 | 0.0 |
Receptors, Corticotropin/antagonists & inhibitors/*metabolism | 2 | 100.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 5 | 0.0 |
Iodine Radioisotopes | 2 | 0.0 |
Receptors, Corticotropin/genetics/*metabolism | 6 | 60.0 |
Proteins/metabolism | 2 | 0.0 |
In Situ Hybridization, Fluorescence | 2 | 0.0 |
Growth | 2 | 4.0 |
Trans-Activation (Genetics) | 2 | 0.0 |
Electric Stimulation | 2 | 0.0 |
Molecular Conformation | 3 | 1.0 |
Receptor, Melanocortin, Type 4/*agonists | 2 | 100.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Cyclic AMP/biosynthesis | 7 | 5.0 |
Drug Design | 5 | 1.0 |
Peptides, Cyclic/*chemical synthesis/chemistry/pharmacology | 3 | 50.0 |
Proteins/*chemistry | 2 | 2.0 |
Bulimia/*genetics | 3 | 60.0 |
Receptor, Melanocortin, Type 4/*genetics/metabolism | 3 | 100.0 |
Receptor, Melanocortin, Type 4/*genetics/physiology | 2 | 100.0 |
Cohort Studies | 4 | 0.0 |
Biological Availability | 2 | 0.0 |
Chromosome Mapping | 2 | 0.0 |
Phylogeny | 2 | 0.0 |
Pro-Opiomelanocortin/*genetics | 2 | 4.0 |
Receptors, Melanocortin/*genetics | 2 | 100.0 |
*Synteny | 2 | 20.0 |
Models, Animal | 2 | 0.0 |
*Sulfonamides | 2 | 3.0 |
Point Mutation | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 2 | 0.0 |
alpha-MSH/metabolism | 4 | 26.0 |
Diet | 2 | 0.0 |
Eating | 3 | 2.0 |
Energy Metabolism/*physiology | 2 | 2.0 |
*Homeostasis | 2 | 3.0 |
Membrane Proteins/metabolism | 2 | 0.0 |
Obesity/genetics/metabolism | 3 | 21.0 |
Energy Metabolism/physiology | 2 | 3.0 |
Obesity/*genetics/metabolism | 4 | 28.0 |
Peptide Fragments/pharmacology | 2 | 0.0 |
Receptors, Corticotropin/genetics/*physiology | 2 | 50.0 |
Gene Expression/physiology | 2 | 0.0 |
RNA, Messenger/analysis | 2 | 0.0 |
Receptors, Corticotropin/*genetics/metabolism | 3 | 33.0 |
Receptors, Corticotropin/deficiency/*genetics | 2 | 100.0 |
