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Taipei Medical University

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Gene Symbol
Gene NameAliasesPrevious_Symbol

HSF1

heat shock transcription factor 1HSTF1


Gene HSF1 gene interaction
View Neighborhood Gene

Result number fewer <<<< << < ALL > >> >>> more

MeSH term
FrequencyCondition_Probility

Adult

30.0

Aged

30.0

Aged, 80 and over

30.0

DNA-Binding Proteins/*genetics

80.0

Gene Expression Regulation, Neoplastic

20.0

Humans

1820.0

Middle Aged

20.0

Research Support, Non-U.S. Gov't

2010.0

Reverse Transcriptase Polymerase Chain Reaction

120.0

Signal Transduction/physiology

30.0

Animals

1740.0

Apoptosis

120.0

Cells, Cultured

320.0

Fibroblasts/cytology/metabolism

21.0

*Gene Expression Regulation

221.0

*Heat

1816.0

Heat-Shock Proteins/*biosynthesis/genetics/metabolism

375.0

*Heat-Shock Response

1571.0

In Vitro

100.0

Mice

720.0

Organ Specificity

60.0

Research Support, U.S. Gov't, P.H.S.

1150.0

Buthionine Sulfoximine/pharmacology

25.0

Cause of Death

21.0

DNA/*metabolism

61.0

DNA-Binding Proteins/*metabolism/physiology

25.0

Female

250.0

Heat

6412.0

Heat-Shock Proteins/genetics

211.0

Male

550.0

Myocardium/*metabolism

62.0

Oxidation-Reduction

80.0

Rats

460.0

Blotting, Western

370.0

DNA-Binding Proteins/metabolism

281.0

Disease Models, Animal

60.0

Dose-Response Relationship, Drug

170.0

Heat-Shock Proteins/*metabolism

1831.0

Heat-Shock Proteins 70/metabolism

917.0

Immunohistochemistry

70.0

Neoplasm Proteins/metabolism

20.0

Quinones/*pharmacology

412.0

Trans-Activation (Genetics)/drug effects

31.0

Analysis of Variance

30.0

Blotting, Northern

150.0

Comparative Study

270.0

DNA-Binding Proteins/genetics/*metabolism

262.0

Electrophoretic Mobility Shift Assay

51.0

Heat-Shock Proteins 70/genetics/*metabolism

318.0

Kinetics

250.0

RNA, Messenger/*metabolism

30.0

Research Support, U.S. Gov't, Non-P.H.S.

390.0

Gene Expression Regulation/*physiology

61.0

Heat-Shock Proteins 70/*genetics/metabolism

770.0

Heat-Shock Response/*genetics

583.0

Phosphorylation

460.0

RNA, Messenger/metabolism

140.0

Trans-Activation (Genetics)/physiology

22.0

Tumor Cells, Cultured

300.0

Cell Line

360.0

DNA-Binding Proteins/biosynthesis/*metabolism

34.0

Drug Combinations

20.0

Embryo

20.0

Fibroblasts

50.0

Gene Expression Regulation/physiology

31.0

RNA, Messenger/biosynthesis

110.0

Time Factors

250.0

Body Temperature

22.0

Cell Nucleus/chemistry

52.0

Cytoplasm/chemistry

42.0

DNA-Binding Proteins/analysis/metabolism

29.0

Isoquinolines/pharmacology

21.0

Rats, Sprague-Dawley

130.0

Sulfonamides/pharmacology

21.0

Heat-Shock Proteins 70/*genetics

1734.0

Heat-Shock Proteins 90/*genetics

240.0

Species Specificity

40.0

Temperature

242.0

Transcription Factors/*genetics

50.0

Heat-Shock Proteins 70/biosynthesis/*genetics

360.0

Binding Sites/genetics

30.0

DNA-Binding Proteins/*genetics/metabolism

81.0

Fluorescent Antibody Technique

40.0

Heat-Shock Proteins/*genetics/metabolism

753.0

Protein Structure, Tertiary/genetics

20.0

Stress/*genetics/metabolism

4100.0

Gene Expression Regulation

190.0

Genes, Reporter

110.0

Heat-Shock Proteins 70/biosynthesis/genetics

466.0

Heat-Shock Response

423.0

Lipopolysaccharides/pharmacology

20.0

Promoter Regions (Genetics)

220.0

Response Elements

20.0

Sodium Salicylate/pharmacology

428.0

Transcription, Genetic

320.0

Cell Survival

110.0

Flow Cytometry

70.0

Heat-Shock Proteins/*biosynthesis

947.0

K562 Cells

122.0

Models, Biological

70.0

PC12 Cells

20.0

Up-Regulation

70.0

Base Sequence

440.0

Cysteine/chemistry/metabolism

240.0

DNA Primers

110.0

DNA-Binding Proteins/chemistry/genetics/*metabolism

52.0

Electrophoresis, Polyacrylamide Gel

110.0

Hela Cells

631.0

Mutagenesis, Site-Directed

130.0

Protein Conformation

130.0

Calcium/*metabolism

20.0

Cell Nucleus/metabolism

201.0

Cycloheximide/pharmacology

81.0

Cytosol/metabolism

30.0

Dactinomycin/pharmacology

20.0

Enzyme Inhibitors/*pharmacology

30.0

Indoles/pharmacology

20.0

Maleimides/pharmacology

22.0

Nitric Oxide/metabolism

31.0

Protein Kinase C/antagonists & inhibitors/metabolism

22.0

RNA, Messenger/analysis

140.0

Microscopy, Electron

20.0

Cell Line, Tumor

60.0

Cell Proliferation

21.0

Cytoplasm/metabolism

60.0

DNA-Binding Proteins/*metabolism

422.0

Glutathione Transferase/metabolism

30.0

Microscopy, Fluorescence

50.0

Mitogen-Activated Protein Kinase 1/metabolism

20.0

Plasmids/metabolism

40.0

Protein Binding

270.0

Protein Biosynthesis

80.0

Trans-Activation (Genetics)

171.0

Transfection

370.0

Cell Death

20.0

Cell Line, Transformed

30.0

DNA-Binding Proteins/genetics/*physiology

73.0

Heat-Shock Proteins/genetics/*physiology

770.0

Mitosis

20.0

Mutation

100.0

Transcription Factors/genetics/*physiology

42.0

Binding Sites

140.0

CHO Cells

80.0

Cell Nucleus/*metabolism

40.0

Hamsters

90.0

Precipitin Tests

70.0

Dose-Response Relationship, Radiation

41.0

Enzyme Inhibitors/pharmacology

130.0

Apoptosis/physiology

30.0

Enzyme Activation

90.0

JNK Mitogen-Activated Protein Kinases

50.0

Mitogen-Activated Protein Kinases/*metabolism

40.0

DNA-Binding Proteins/*genetics/*metabolism

42.0

Fibroblasts/cytology

20.0

Gene Deletion

20.0

Heat-Shock Proteins/genetics/metabolism

850.0

Heat-Shock Proteins 70/genetics/metabolism

1266.0

Molecular Chaperones/metabolism

24.0

Acclimatization

220.0

Cold

21.0

DNA/metabolism

241.0

Heat-Shock Proteins 70/biosynthesis

562.0

Carrageenan

337.0

Cyclooxygenase Inhibitors/pharmacology

22.0

Indomethacin/pharmacology

31.0

NF-kappa B/*metabolism

20.0

Pleurisy/chemically induced/*metabolism

266.0

Rats, Wistar

100.0

Amino Acid Sequence

300.0

Chromatography, Gel

20.0

Conserved Sequence

20.0

Molecular Sequence Data

560.0

Protein Folding

30.0

Protein Structure, Secondary

30.0

Repetitive Sequences, Amino Acid

21.0

Structure-Activity Relationship

40.0

3T3 Cells

100.0

DNA-Binding Proteins/biosynthesis

22.0

Dimerization

30.0

Fluorescent Antibody Technique, Indirect

60.0

Heat-Shock Proteins/biosynthesis

450.0

Heat-Shock Proteins 90/metabolism

310.0

Luciferases/metabolism

40.0

Recombinant Proteins/metabolism

80.0

Stress

59.0

Active Transport, Cell Nucleus

20.0

Amino Acid Substitution

50.0

Chick Embryo

40.0

Dogs

20.0

Phenotype

40.0

Protein Structure, Tertiary

90.0

Cysteine Endopeptidases/metabolism

41.0

DNA-Binding Proteins/chemistry/*metabolism

52.0

Enzyme Activation/drug effects

40.0

Imidazoles/pharmacology

20.0

Leupeptins/pharmacology

43.0

Mitogen-Activated Protein Kinase 9

26.0

Multienzyme Complexes/antagonists & inhibitors/metabolism

313.0

Proteasome Endopeptidase Complex

101.0

Pyridines/pharmacology

20.0

Rabbits

50.0

Recombinant Fusion Proteins/biosynthesis

51.0

Signal Transduction/drug effects

20.0

*Trans-Activation (Genetics)/drug effects

24.0

Cell Compartmentation

30.0

DNA-Binding Proteins/genetics/isolation & purification/*metabolism

26.0

Protein Processing, Post-Translational

30.0

Protein Transport

20.0

Heat Stress Disorders/*metabolism

2100.0

Sequence Homology, Amino Acid

80.0

Caspases/metabolism

20.0

DNA-Binding Proteins/physiology

72.0

Diterpenes/*pharmacology

26.0

Heat-Shock Proteins 70/*biosynthesis

853.0

Mitogen-Activated Protein Kinases/metabolism

60.0

Oxidants/*pharmacology

28.0

Phosphorylation/drug effects

30.0

Tissue Distribution

50.0

Chloramphenicol O-Acetyltransferase/genetics

31.0

DNA-Binding Proteins/*antagonists & inhibitors

211.0

Dexamethasone/pharmacology

20.0

Glucocorticoids/pharmacology

21.0

Point Mutation

70.0

Signal Transduction

60.0

Cell Hypoxia/drug effects

233.0

DNA-Binding Proteins/*biosynthesis

32.0

L-Lactate Dehydrogenase/metabolism

32.0

Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism

30.0

Serine/*metabolism

33.0

Transcription Factors/chemistry/*metabolism

32.0

Stress, Mechanical

41.0

Culture Media, Serum-Free

20.0

Cysteine Endopeptidases/*metabolism

31.0

Cysteine Proteinase Inhibitors/pharmacology

41.0

Fibroblasts/*physiology

23.0

Multienzyme Complexes/*metabolism

32.0

RNA, Messenger/genetics

70.0

Gene Expression/drug effects

30.0

*Avian Proteins

66.0

Cell Cycle/*physiology

20.0

Chickens

50.0

Cloning, Molecular

190.0

Heat-Shock Proteins/genetics/*metabolism

1035.0

Heat-Shock Proteins 90/genetics/*metabolism

360.0

Liver/metabolism

20.0

Transcription Factors/genetics/*metabolism

70.0

Heat-Shock Proteins/chemistry/genetics/*metabolism

250.0

Heat-Shock Response/*physiology

562.0

Phylogeny

20.0

Sequence Alignment

40.0

Transcription Factors/chemistry/genetics/*metabolism

21.0

Cadmium Chloride/*pharmacology

266.0

DNA-Binding Proteins/chemistry/drug effects/*metabolism

2100.0

Tumor Cells, Cultured/metabolism

21.0

Binding, Competitive

30.0

DNA-Binding Proteins/*biosynthesis/genetics/metabolism

218.0

*Gene Expression Regulation, Developmental

40.0

Heat-Shock Proteins 70/genetics

1027.0

Immunoblotting

30.0

*Promoter Regions (Genetics)

60.0

Transcription Factors/*biosynthesis/genetics

22.0

Acetylcysteine/pharmacology

22.0

Arsenites/*pharmacology

316.0

Flavonoids/pharmacology

20.0

*Gene Expression Regulation, Neoplastic

20.0

Heat-Shock Proteins 70/*metabolism

830.0

Anti-Inflammatory Agents, Non-Steroidal/pharmacology

22.0

Child

20.0

Heat-Shock Response/drug effects/*physiology

3100.0

Gene Expression/physiology

30.0

Luciferases/genetics

41.0

Trans-Activation (Genetics)/*physiology

21.0

Fibroblasts/cytology/drug effects/metabolism

35.0

*Antigens, Nuclear

53.0

*DNA Helicases

52.0

*Saccharomyces cerevisiae Proteins

121.0

Heat-Shock Proteins/metabolism

1424.0

Hemodynamic Processes

21.0

Hydrogen-Ion Concentration

20.0

Myocardial Reperfusion

211.0

DNA-Binding Proteins/genetics

50.0

Glutathione/metabolism

52.0

Heat-Shock Proteins/*genetics

1319.0

Mice, Inbred ICR

20.0

Oxidative Stress/*physiology

22.0

Plants, Toxic

25.0

Recombinant Fusion Proteins/genetics/metabolism

30.0

Trans-Activators

24.0

Crosses, Genetic

20.0

Alternative Splicing

20.0

Brain/embryology

24.0

Protein Isoforms

30.0

Models, Genetic

60.0

Recombinant Fusion Proteins/metabolism

50.0

Regulatory Sequences, Nucleic Acid

50.0

Trans-Activation (Genetics)/*genetics

55.0

Trans-Activators/genetics/metabolism

21.0

Promoter Regions (Genetics)/genetics

50.0

*Gene Expression Regulation/drug effects

31.0

Heat-Shock Proteins/*physiology

433.0

Promoter Regions (Genetics)/*genetics

20.0

DNA-Binding Proteins/biosynthesis/*physiology

215.0

DNA-Binding Proteins/biosynthesis/genetics/*physiology

25.0

Mice, Inbred BALB C

40.0

Mice, Knockout

100.0

*Heat-Shock Proteins

34.0

Sequence Deletion

60.0

DNA-Binding Proteins/*physiology

81.0

English Abstract

50.0

Tumor Cells, Cultured/*physiology

215.0

U937 Cells

20.0

Fibroblasts/metabolism

20.0

*Trans-Activation (Genetics)

81.0

Transcription Factors/*metabolism

201.0

Glycogen Synthase Kinase 3

22.0

Glycogen Synthase Kinases

23.0

Transcription, Genetic/*drug effects

30.0

Xenopus laevis

51.0

Fever/*metabolism

240.0

Apoptosis/*physiology

30.0

Chloramphenicol O-Acetyltransferase/genetics/metabolism

21.0

Transcription Factors/genetics/metabolism

20.0

RNA, Messenger/biosynthesis/genetics

20.0

Stress/physiopathology

28.0

DNA Primers/genetics

20.0

Gene Expression

100.0

Mice, Inbred C57BL

70.0

Mice, Transgenic

70.0

Myocardium/metabolism

20.0

Aging/*metabolism

31.0

Macromolecular Substances

60.0

Rats, Inbred F344

51.0

Transcription Factors/metabolism

161.0

Ubiquitins/genetics/*metabolism

29.0

Oligonucleotide Array Sequence Analysis

20.0

Cyclosporine/*pharmacology

32.0

Anti-Inflammatory Agents, Non-Steroidal/*pharmacology

43.0

Indomethacin/*pharmacology

25.0

Stress/genetics/metabolism

327.0

Heat-Shock Proteins/*genetics/*metabolism

466.0

Antioxidants/pharmacology

21.0

DNA-Binding Proteins/genetics/metabolism

40.0

Swine

30.0

Up-Regulation/drug effects

20.0

Cell Division

30.0

Chromatin/metabolism

20.0

DNA, Complementary/metabolism

20.0

DNA-Binding Proteins/*genetics/*physiology

25.0

Enzyme-Linked Immunosorbent Assay

20.0

Inflammation

20.0

Stress/*physiopathology

26.0

Arsenites/pharmacology

421.0

Azetidinecarboxylic Acid/pharmacology

2100.0

Protein Synthesis Inhibitors/pharmacology

30.0

Sodium Compounds/pharmacology

214.0

Sulfhydryl Compounds/metabolism

25.0

Chloramphenicol O-Acetyltransferase/biosynthesis

32.0

*Transcription, Genetic

120.0

Heating

29.0

Acetylcysteine/*analogs & derivatives/pharmacology

37.0

Cysteine Proteinase Inhibitors/*pharmacology

413.0

Down-Regulation

30.0

Gene Expression Regulation/drug effects

70.0

Leupeptins/*pharmacology

430.0

Heat-Shock Proteins/*biosynthesis/genetics

457.0

Green Fluorescent Proteins

20.0

*Mutation

20.0

Transcription Factors/*genetics/*metabolism

21.0

Ca(2+)-Calmodulin Dependent Protein Kinase/*metabolism

20.0

Doxorubicin/pharmacology

20.0

*Mitogen-Activated Protein Kinases

30.0

Stress/metabolism/*physiopathology

240.0

Saccharomyces cerevisiae/genetics

40.0

Transcription, Genetic/drug effects

30.0

*Chromosome Mapping

20.0

Cercopithecus aethiops

20.0

DNA-Binding Proteins/analysis/*biosynthesis

325.0

Biological Transport

20.0

Cell Nucleus/*metabolism/ultrastructure

26.0

Chimeric Proteins/chemistry/metabolism

23.0

Genetic Complementation Test

30.0

Oncorhynchus mykiss/*metabolism

375.0

Testis/metabolism

31.0

In Situ Hybridization, Fluorescence

20.0

Sequence Analysis, DNA

40.0

*Apoptosis

20.0

Plasmids

20.0

Protein-Serine-Threonine Kinases/*physiology

21.0

Cell Cycle

30.0

Multigene Family

20.0

*Oxidative Stress

20.0

Heat-Shock Response/physiology

228.0

DNA-Binding Proteins/genetics/metabolism/*physiology

23.0

Age Factors

30.0

Animals, Newborn

30.0

Catalysis

20.0

Transcription Factors/*physiology

20.0

DNA-Binding Proteins/*biosynthesis/genetics

33.0

Genetic Vectors

20.0

Heat/*adverse effects

218.0

Gene Expression Regulation, Neoplastic/drug effects

20.0

Mitogen-Activated Protein Kinase 3

20.0

Leukemia, Erythroblastic, Acute

55.0

Tetradecanoylphorbol Acetate/pharmacology

20.0

Hemin/*physiology

240.0

Recombinant Fusion Proteins/genetics

21.0

Transcription, Genetic/*physiology

21.0

Trans-Activators/*metabolism

40.0

Hemin/pharmacology

420.0

Mammals

41.0

*Ultraviolet Rays

20.0

Gene Expression Regulation, Developmental

40.0

Gene Expression Regulation, Plant

26.0

Azetidines/pharmacology

342.0

Glutathione/*metabolism

23.0

Glutathione Disulfide/metabolism

216.0

Hydrogen Peroxide/pharmacology

20.0

Heat-Shock Proteins/physiology

222.0

Transcription Factors/genetics

20.0

Heat-Shock Response/genetics/*physiology

2100.0

Subcellular Fractions/metabolism

20.0

Cell Aging

22.0

Heat-Shock Proteins/drug effects/*metabolism

2100.0

Heat-Shock Proteins/chemistry/genetics/*physiology

266.0

Peptide Mapping

51.0

Phosphorus Radioisotopes

23.0

Cell Extracts

21.0

Chimeric Proteins

33.0

Fungal Proteins/genetics/metabolism

22.0

*Nuclear Proteins

20.0

RNA Splicing

20.0

DNA, Complementary/genetics

50.0

Heat-Shock Proteins 70/*biosynthesis/genetics

466.0

Protein Kinase C/metabolism

20.0

Tumor Cells, Cultured/drug effects

20.0

Spermatogenesis/*physiology

25.0

Gene Expression Regulation/*genetics

21.0

Gene Targeting

20.0

Oocytes/*physiology

25.0

Transcription Factors/biosynthesis/*metabolism

24.0

Genotype

20.0

Microscopy, Confocal

20.0

DNA Footprinting

20.0

Phosphoprotein Phosphatase/*metabolism

22.0

Heat-Shock Proteins 90/genetics/metabolism

250.0

Xenopus

20.0

Transcription Factors/biosynthesis

33.0

Cell Differentiation/drug effects

20.0

DNA-Binding Proteins/drug effects/genetics/*metabolism

214.0

Quercetin/*pharmacology

28.0

Oligodeoxyribonucleotides

40.0

Transcription Factors/*biosynthesis

43.0

Stress/genetics/*metabolism

222.0

*DNA Repair

20.0

Nuclear Proteins/*metabolism

40.0

Protein-Serine-Threonine Kinases/*metabolism

20.0

Dithiothreitol/pharmacology

33.0

Protein Kinases/metabolism

20.0

Oxidative Stress

20.0

COS Cells

50.0

Serine/chemistry

42.0

Blastocyst

216.0

Carcinoma, Embryonal

213.0

*Embryonic and Fetal Development

21.0

Mice, Inbred Strains

20.0

Heat-Shock Response/*drug effects

4100.0

Biopolymers

21.0

Phosphoprotein Phosphatase/antagonists & inhibitors

26.0

Spermatogenesis/*genetics

24.0

Transcription Factors/physiology

20.0

Recombinant Proteins/isolation & purification

24.0

Mice, Inbred C3H

20.0

Cadmium/pharmacology

28.0

Polymerase Chain Reaction

40.0

Transcription Factors/*genetics/metabolism

20.0

Molecular Weight

40.0

Signal Transduction/*drug effects

20.0

Gene Expression/*drug effects

20.0

Guinea Pigs

20.0

Aging/*physiology

20.0

DNA-Binding Proteins/metabolism/*physiology

21.0

Transcription Factors/metabolism/*physiology

22.0

Transcription, Genetic/*genetics

31.0

*Stress

215.0

DNA-Binding Proteins/analysis

22.0

Heat-Shock Proteins/*analysis

240.0

Heat-Shock Proteins 70/*analysis

2100.0

Transcription Factors/analysis

22.0

Chromatography, Affinity

20.0

Nuclear Proteins/metabolism

20.0

*Intracellular Signaling Peptides and Proteins

30.0

Two-Hybrid System Techniques

20.0

*Transcription, Genetic/drug effects

21.0

Mice, Inbred CBA

20.0

RNA, Messenger/analysis/genetics

20.0

Substrate Specificity

20.0

Leucine Zippers/genetics

24.0

Escherichia coli/genetics

20.0

Consensus Sequence

30.0

Oligodeoxyribonucleotides/chemistry

20.0

Genes, Structural

20.0

Chromosomes, Human, Pair 9/genetics

21.0

Heterochromatin/genetics

228.0

RNA-Binding Proteins/metabolism

22.0

Radiation Dosage

22.0

Gene Expression Profiling

20.0

Drosophila/genetics

21.0

Hela Cells/physiology

28.0

Sequence Homology, Nucleic Acid

20.0

In Situ Nick-End Labeling

20.0

NF-kappa B/metabolism

20.0

Mice, Mutant Strains

20.0

Recombinant Proteins/genetics/metabolism

20.0

Protein Structure, Tertiary/physiology

21.0

DNA-Binding Proteins/deficiency/genetics/*physiology

28.0

Lysine/chemistry

22.0