MeSH term
Frequency | Condition_Probility | Aged | 6 | 0.0 |
Aged, 80 and over | 5 | 0.0 |
Female | 45 | 0.0 |
Humans | 622 | 0.0 |
Animals | 397 | 0.0 |
Mice | 215 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 291 | 0.0 |
Signal Transduction/drug effects | 10 | 1.0 |
Adaptor Proteins, Signal Transducing/*metabolism | 3 | 27.0 |
Down-Regulation | 12 | 0.0 |
Enzyme Activation/drug effects | 16 | 1.0 |
Enzyme Inhibitors/pharmacology | 24 | 0.0 |
Fibroblast Growth Factors/*pharmacology | 2 | 4.0 |
Genistein/pharmacology | 2 | 1.0 |
Mitogen-Activated Protein Kinase 1/*metabolism | 7 | 5.0 |
RNA, Messenger/genetics/metabolism | 4 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 40 | 0.0 |
Tumor Cells, Cultured | 128 | 0.0 |
Amino Acid Motifs | 13 | 1.0 |
Amino Acid Sequence | 186 | 0.0 |
Binding Sites | 83 | 1.0 |
Cell Line | 181 | 0.0 |
Chickens | 5 | 0.0 |
In Vitro | 12 | 0.0 |
Molecular Sequence Data | 192 | 0.0 |
Protein Binding | 163 | 1.0 |
Recombinant Proteins/chemistry/genetics/metabolism | 2 | 0.0 |
Research Support, Non-U.S. Gov't | 489 | 0.0 |
Transfection | 115 | 0.0 |
Tyrosine/chemistry | 6 | 4.0 |
src Homology Domains | 134 | 23.0 |
*Adaptor Proteins, Signal Transducing | 446 | 34.0 |
Cell Nucleus/metabolism | 8 | 0.0 |
Cytoplasm/metabolism | 13 | 1.0 |
Macromolecular Substances | 32 | 1.0 |
Protein Transport | 4 | 0.0 |
Proteins/*chemistry/*metabolism | 4 | 12.0 |
RNA-Binding Proteins/*metabolism | 3 | 3.0 |
Rats | 85 | 0.0 |
Receptor, Insulin/*metabolism | 11 | 19.0 |
*Signal Transduction | 115 | 5.0 |
Son of Sevenless Proteins/*metabolism | 5 | 83.0 |
*src Homology Domains | 66 | 34.0 |
Enzyme Activation | 117 | 3.0 |
Immunohistochemistry | 4 | 0.0 |
Mitogen-Activated Protein Kinase 1/metabolism | 9 | 2.0 |
Mitogen-Activated Protein Kinase 3 | 27 | 4.0 |
Mitogen-Activated Protein Kinases/metabolism | 43 | 4.0 |
Phosphorylation | 325 | 4.0 |
Proteins/*physiology | 11 | 5.0 |
Rats, Sprague-Dawley | 6 | 0.0 |
Signal Transduction/*physiology | 49 | 4.0 |
Tyrosine/*metabolism | 43 | 12.0 |
Actins/metabolism | 6 | 1.0 |
Antigens, CD3/metabolism | 3 | 1.0 |
Cell Line, Transformed | 11 | 0.0 |
Gene Transfer Techniques | 2 | 0.0 |
Mutation | 38 | 0.0 |
Proteins/*genetics | 11 | 0.0 |
Receptors, Antigen, T-Cell/metabolism | 13 | 7.0 |
Base Sequence | 59 | 0.0 |
Chimeric Proteins/metabolism | 4 | 2.0 |
DNA Primers | 13 | 0.0 |
Dogs | 6 | 0.0 |
Glutathione Transferase/genetics/metabolism | 6 | 5.0 |
Mice, Knockout | 10 | 0.0 |
Morphogenesis/*physiology | 2 | 20.0 |
Recombinant Fusion Proteins/metabolism | 57 | 3.0 |
CHO Cells | 26 | 1.0 |
Hamsters | 35 | 0.0 |
Models, Biological | 31 | 1.0 |
Receptor, Epidermal Growth Factor/*metabolism | 47 | 6.0 |
Signal Transduction/physiology | 24 | 2.0 |
ras Proteins/*metabolism | 22 | 14.0 |
Adolescent | 2 | 0.0 |
Arginine | 2 | 2.0 |
Cell Differentiation | 16 | 0.0 |
Cells, Cultured | 62 | 0.0 |
Proline | 6 | 10.0 |
Transcription Factors/*genetics | 2 | 0.0 |
*Variation (Genetics) | 2 | 0.0 |
Blotting, Western | 47 | 0.0 |
Carrier Proteins/metabolism | 8 | 1.0 |
Electrophoresis, Gel, Two-Dimensional | 5 | 1.0 |
Jurkat Cells | 38 | 2.0 |
Membrane Glycoproteins/genetics/*metabolism | 2 | 1.0 |
Protein Binding/physiology | 3 | 1.0 |
Proteins/metabolism | 136 | 14.0 |
src Homology Domains/physiology | 5 | 11.0 |
Actins/*metabolism | 3 | 1.0 |
Fluorescent Antibody Technique | 5 | 0.0 |
Green Fluorescent Proteins | 8 | 0.0 |
Hela Cells | 23 | 0.0 |
Oncogene Proteins/genetics/*metabolism | 7 | 14.0 |
Proteins/chemistry/genetics/*metabolism | 8 | 9.0 |
Recombinant Fusion Proteins/genetics/metabolism | 10 | 0.0 |
Signal Transduction | 150 | 2.0 |
*Adaptor Proteins, Vesicular Transport | 103 | 40.0 |
Endocytosis/*physiology | 3 | 2.0 |
Endosomes/metabolism | 2 | 1.0 |
Guanosine Triphosphate/metabolism | 13 | 4.0 |
Microscopy, Fluorescence | 11 | 0.0 |
Proteins/*metabolism | 126 | 14.0 |
ras Proteins/immunology/*metabolism | 2 | 100.0 |
Cell Adhesion/physiology | 5 | 1.0 |
Crystallography, X-Ray | 5 | 0.0 |
Models, Molecular | 20 | 0.0 |
Phosphoproteins/chemistry/metabolism | 3 | 13.0 |
Sequence Alignment | 14 | 0.0 |
Tyrosine/metabolism | 91 | 7.0 |
B-Lymphocytes/*immunology | 4 | 0.0 |
Ligands | 32 | 1.0 |
Signal Transduction/immunology | 4 | 1.0 |
Binding Sites/genetics | 9 | 0.0 |
Carrier Proteins/chemistry/*genetics/*metabolism | 2 | 7.0 |
Gene Expression | 21 | 0.0 |
Mutagenesis, Site-Directed | 50 | 1.0 |
Phosphoproteins/*genetics/*metabolism | 2 | 14.0 |
Receptor, Macrophage Colony-Stimulating Factor/genetics/metabolism | 2 | 66.0 |
Sequence Homology, Amino Acid | 42 | 0.0 |
3T3 Cells | 80 | 3.0 |
Membrane Proteins/genetics/*metabolism | 7 | 2.0 |
PC12 Cells | 13 | 3.0 |
Phosphoproteins/genetics/*metabolism | 14 | 8.0 |
Proteins/genetics/*metabolism | 34 | 7.0 |
Proto-Oncogene Proteins/genetics/*metabolism | 10 | 2.0 |
Receptors, Fibroblast Growth Factor/*metabolism | 2 | 3.0 |
Cell Differentiation/physiology | 3 | 0.0 |
Cell Division/physiology | 12 | 1.0 |
Protein Isoforms | 5 | 0.0 |
*Apoptosis | 2 | 0.0 |
Enzyme Inhibitors/*pharmacology | 4 | 0.0 |
*Protein-Serine-Threonine Kinases | 18 | 2.0 |
Proto-Oncogene Proteins/metabolism | 31 | 2.0 |
Blotting, Northern | 11 | 0.0 |
Chromosomes, Human, Pair 17/*genetics | 2 | 1.0 |
Gene Amplification | 2 | 0.0 |
Gene Expression Profiling | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 10 | 0.0 |
Carrier Proteins/genetics/*metabolism | 9 | 2.0 |
*DNA-Binding Proteins | 7 | 0.0 |
Gene Expression Regulation | 17 | 0.0 |
Genes, Reporter | 10 | 0.0 |
Lymphocyte Activation | 20 | 0.0 |
Lymphocytes/*metabolism | 2 | 1.0 |
Receptors, Antigen, T-Cell/*metabolism | 16 | 11.0 |
*Transcription Factors | 7 | 0.0 |
ras Proteins/metabolism | 19 | 12.0 |
Cytoskeletal Proteins/metabolism | 3 | 1.0 |
Dose-Response Relationship, Drug | 16 | 0.0 |
Epidermal Growth Factor/metabolism | 5 | 1.0 |
Immunoblotting | 22 | 0.0 |
Protein Binding/drug effects | 7 | 1.0 |
Down-Regulation/drug effects | 2 | 0.0 |
Epidermal Growth Factor/*metabolism | 3 | 0.0 |
*Intercellular Signaling Peptides and Proteins | 2 | 0.0 |
Signal Transduction/*drug effects | 17 | 4.0 |
DNA Mutational Analysis | 11 | 0.0 |
In Situ Hybridization, Fluorescence | 2 | 0.0 |
Male | 18 | 0.0 |
Syndrome | 2 | 0.0 |
Cell Transformation, Neoplastic/*metabolism | 2 | 5.0 |
Epithelial Cells/metabolism | 3 | 0.0 |
Isoenzymes/genetics/*metabolism | 2 | 2.0 |
Mice, Inbred BALB C | 6 | 0.0 |
Mice, Nude | 11 | 0.0 |
Neoplasm Metastasis | 5 | 0.0 |
Oncogene Proteins, Fusion/genetics/*metabolism | 2 | 5.0 |
Phosphoproteins/metabolism | 36 | 5.0 |
Precipitin Tests | 67 | 2.0 |
Rats, Inbred F344 | 2 | 0.0 |
Drug Design | 6 | 1.0 |
English Abstract | 6 | 0.0 |
Protein-Tyrosine Kinase/antagonists & inhibitors | 2 | 0.0 |
DNA/biosynthesis | 10 | 1.0 |
Epidermal Growth Factor/pharmacology | 24 | 2.0 |
Insulin/pharmacology | 9 | 3.0 |
Insulin-Like Growth Factor I/pharmacology | 4 | 2.0 |
Mitogens/*pharmacology | 2 | 1.0 |
Phosphorylation/drug effects | 21 | 2.0 |
Phosphotyrosine/*metabolism | 7 | 11.0 |
Protein Structure, Tertiary | 45 | 1.0 |
Proto-Oncogene Proteins c-raf/metabolism | 5 | 5.0 |
Swine | 5 | 0.0 |
Glutathione Transferase/genetics | 8 | 2.0 |
Immunosorbent Techniques | 8 | 2.0 |
*Lymphocyte Activation | 9 | 0.0 |
Organ Specificity | 6 | 0.0 |
Peptide Fragments/genetics | 2 | 2.0 |
Peptide Library | 3 | 2.0 |
Polymerase Chain Reaction | 16 | 0.0 |
RNA, Messenger/analysis | 4 | 0.0 |
T-Lymphocytes/*immunology | 9 | 0.0 |
COS Cells | 44 | 1.0 |
Cercopithecus aethiops | 11 | 0.0 |
Luminescent Proteins/genetics | 3 | 1.0 |
Molecular Weight | 23 | 0.0 |
Substrate Specificity | 17 | 0.0 |
Cytoskeleton/metabolism | 6 | 2.0 |
*Lectins, C-Type | 2 | 1.0 |
Mitogen-Activated Protein Kinases/*metabolism | 14 | 2.0 |
Platelet Aggregation | 3 | 1.0 |
Thrombin/pharmacology | 4 | 1.0 |
src-Family Kinases/physiology | 3 | 9.0 |
Comparative Study | 37 | 0.0 |
Endosomes/*metabolism | 2 | 1.0 |
Cell Differentiation/drug effects | 2 | 0.0 |
Cell Division/drug effects | 20 | 0.0 |
Fusion Proteins, bcr-abl/metabolism | 2 | 12.0 |
Genes, fos/genetics | 3 | 6.0 |
Proto-Oncogene Proteins/metabolism/*physiology | 3 | 6.0 |
Trans-Activation (Genetics)/drug effects | 3 | 1.0 |
Endothelium, Vascular/cytology/metabolism | 2 | 1.0 |
Mice, Inbred C57BL | 8 | 0.0 |
*Proto-Oncogene Proteins | 29 | 1.0 |
*Endocytosis | 3 | 1.0 |
Rabbits | 16 | 0.0 |
Receptor, Epidermal Growth Factor/*genetics/physiology | 2 | 25.0 |
*Signal Transduction/genetics | 2 | 7.0 |
*Ubiquitin-Protein Ligases | 31 | 5.0 |
Ubiquitins/metabolism | 2 | 1.0 |
*MAP Kinase Kinase Kinase 1 | 6 | 4.0 |
*MAP Kinase Signaling System | 4 | 3.0 |
Mitogen-Activated Protein Kinase 1/physiology | 2 | 11.0 |
Mitogen-Activated Protein Kinases/physiology | 5 | 4.0 |
Protein-Serine-Threonine Kinases/physiology | 4 | 4.0 |
ras Proteins | 2 | 22.0 |
Binding, Competitive | 16 | 0.0 |
Enzyme-Linked Immunosorbent Assay | 4 | 0.0 |
Gene Library | 5 | 0.0 |
Glutathione Transferase/metabolism | 17 | 2.0 |
Peptides/chemistry | 10 | 2.0 |
DNA/*biosynthesis | 2 | 2.0 |
Fibroblasts | 5 | 0.0 |
Gene Expression Regulation, Enzymologic/genetics | 2 | 3.0 |
Insulin/*pharmacology | 16 | 7.0 |
Recombinant Fusion Proteins | 9 | 2.0 |
Stimulation, Chemical | 3 | 0.0 |
Carrier Proteins/physiology | 3 | 2.0 |
Interleukin-2/*pharmacology | 4 | 1.0 |
K562 Cells | 8 | 1.0 |
*Membrane Proteins | 14 | 1.0 |
Nuclear Proteins/physiology | 3 | 3.0 |
Phosphoproteins/physiology | 6 | 10.0 |
Phosphotyrosine/metabolism | 55 | 13.0 |
Proteins/physiology | 12 | 8.0 |
Proto-Oncogene Proteins/physiology | 8 | 6.0 |
Protein-Tyrosine Kinase/metabolism | 51 | 5.0 |
Kinetics | 38 | 0.0 |
Carrier Proteins/chemistry/*physiology | 2 | 5.0 |
Phosphoproteins/chemistry/*physiology | 2 | 22.0 |
Signal Transduction/*immunology | 10 | 2.0 |
*Caenorhabditis elegans Proteins | 4 | 3.0 |
Receptor, Epidermal Growth Factor/*physiology | 9 | 6.0 |
JNK Mitogen-Activated Protein Kinases | 16 | 2.0 |
Nerve Growth Factor/pharmacology | 2 | 6.0 |
Receptor, Epidermal Growth Factor/physiology | 2 | 2.0 |
Receptors, Growth Factor/*physiology | 3 | 10.0 |
Signal Transduction/genetics | 7 | 2.0 |
Carrier Proteins/*metabolism | 14 | 1.0 |
Dynamins | 9 | 21.0 |
GTP Phosphohydrolases/*metabolism | 3 | 2.0 |
SOS1 Protein/metabolism | 3 | 30.0 |
Electrophoresis, Polyacrylamide Gel | 26 | 0.0 |
Gene Deletion | 3 | 0.0 |
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/metabolism | 4 | 7.0 |
Point Mutation | 19 | 0.0 |
U937 Cells | 6 | 1.0 |
src-Family Kinases/chemistry/*metabolism | 3 | 42.0 |
Cell Line, Tumor | 14 | 0.0 |
Immunologic Techniques | 2 | 0.0 |
Immunoprecipitation | 3 | 1.0 |
Recombinant Proteins/chemistry | 2 | 0.0 |
Fibroblasts/metabolism | 10 | 1.0 |
Fusion Proteins, bcr-abl/*metabolism | 5 | 14.0 |
MAP Kinase Signaling System | 11 | 4.0 |
Peptide Mapping | 8 | 1.0 |
Son of Sevenless Protein, Drosophila/metabolism | 3 | 100.0 |
Spectrum Analysis, Mass | 3 | 0.0 |
Time Factors | 26 | 0.0 |
Transformation, Genetic | 4 | 2.0 |
1-Phosphatidylinositol 3-Kinase/metabolism | 22 | 4.0 |
Isoenzymes/metabolism | 20 | 3.0 |
Mitosis/*physiology | 4 | 4.0 |
Proteins/genetics/metabolism/*physiology | 3 | 8.0 |
Reference Values | 2 | 0.0 |
DNA/metabolism | 6 | 0.0 |
Phosphoproteins/*metabolism | 35 | 7.0 |
Receptor Protein-Tyrosine Kinases/metabolism | 14 | 5.0 |
Retroviridae/genetics | 2 | 0.0 |
Gene Expression Regulation, Neoplastic | 11 | 0.0 |
Proto-Oncogene Proteins/*physiology | 6 | 2.0 |
Antigens, CD/genetics/*metabolism | 2 | 2.0 |
Cell Division/*physiology | 2 | 1.0 |
Culture Media, Serum-Free | 4 | 1.0 |
MAP Kinase Signaling System/physiology | 3 | 3.0 |
Mitogens/pharmacology | 4 | 1.0 |
Serine/metabolism | 5 | 1.0 |
src-Family Kinases/metabolism | 13 | 6.0 |
Bromodeoxyuridine/metabolism | 2 | 2.0 |
Microtubules/metabolism | 3 | 2.0 |
Prognosis | 2 | 0.0 |
1-Phosphatidylinositol 3-Kinase/antagonists & inhibitors/metabolism | 2 | 2.0 |
Apoptosis/drug effects | 2 | 0.0 |
Cell Survival | 5 | 0.0 |
Chromones/pharmacology | 6 | 2.0 |
Flavonoids/pharmacology | 8 | 2.0 |
MAP Kinase Kinase 1 | 10 | 6.0 |
Membrane Glycoproteins/pharmacology | 2 | 3.0 |
Mitogen-Activated Protein Kinase Kinases/*metabolism | 2 | 3.0 |
Morpholines/pharmacology | 6 | 2.0 |
Protein-Serine-Threonine Kinases/*metabolism | 11 | 1.0 |
Proteins/metabolism/pharmacology | 2 | 33.0 |
Proto-Oncogene Proteins/*metabolism | 35 | 3.0 |
Tumor Necrosis Factor-alpha/*pharmacology | 2 | 0.0 |
Antibodies, Monoclonal/pharmacology | 3 | 0.0 |
Apoptosis/*physiology | 3 | 0.0 |
Blotting, Western/methods | 2 | 1.0 |
Enzyme-Linked Immunosorbent Assay/methods | 2 | 0.0 |
Luminescent Proteins/metabolism | 3 | 0.0 |
Neuroblastoma | 2 | 1.0 |
Peptide Fragments/metabolism | 8 | 2.0 |
Proteins/immunology/*metabolism | 2 | 11.0 |
Staurosporine/pharmacology | 2 | 1.0 |
Cell Movement | 7 | 0.0 |
DNA, Complementary/metabolism | 11 | 0.0 |
Oncogene Proteins/*metabolism | 6 | 7.0 |
B-Lymphocytes/metabolism | 5 | 2.0 |
Carrier Proteins/*metabolism/*physiology | 2 | 13.0 |
Cell Membrane/metabolism | 15 | 0.0 |
Killer Cells, Natural/metabolism | 2 | 3.0 |
Phospholipase C/metabolism | 28 | 9.0 |
T-Lymphocytes/metabolism | 7 | 2.0 |
Cell Movement/physiology | 2 | 0.0 |
Receptor, erbB-2/genetics/*metabolism | 2 | 6.0 |
rac1 GTP-Binding Protein/metabolism | 3 | 3.0 |
src Homology Domains/genetics | 13 | 23.0 |
Receptor, IGF Type 1/*metabolism | 4 | 11.0 |
Cell Membrane/enzymology | 2 | 0.0 |
Exons | 4 | 0.0 |
Isoenzymes/chemistry/genetics/metabolism | 2 | 6.0 |
Open Reading Frames | 2 | 0.0 |
Sequence Homology, Nucleic Acid | 2 | 0.0 |
Antigens, CD/*physiology | 7 | 2.0 |
*Cell Adhesion Molecules | 4 | 1.0 |
*Lectins | 4 | 2.0 |
Phenotype | 8 | 0.0 |
Protein-Tyrosine-Phosphatase/*metabolism | 27 | 21.0 |
Receptors, Antigen, B-Cell/*physiology | 14 | 18.0 |
Cytoskeleton/physiology | 2 | 2.0 |
Protein Isoforms/metabolism | 2 | 1.0 |
Protein-Tyrosine Kinase/genetics/*metabolism | 9 | 6.0 |
Recombinant Proteins/metabolism | 27 | 1.0 |
Threonine/metabolism | 3 | 3.0 |
Cell Membrane Permeability | 2 | 1.0 |
MAP Kinase Signaling System/drug effects | 2 | 2.0 |
Proteins/*antagonists & inhibitors/chemistry | 3 | 100.0 |
Peptides/metabolism | 4 | 1.0 |
Proline/metabolism | 7 | 10.0 |
DNA-Binding Proteins/*metabolism | 7 | 0.0 |
Dimerization | 10 | 0.0 |
Liver/metabolism | 6 | 0.0 |
NF-kappa B/*metabolism | 2 | 0.0 |
Plasmids/metabolism | 11 | 0.0 |
Promoter Regions (Genetics) | 6 | 0.0 |
Protein-Tyrosine Kinase/*metabolism | 43 | 5.0 |
Proto-Oncogene Protein pp60(c-src)/metabolism | 5 | 12.0 |
*Trans-Activation (Genetics) | 5 | 0.0 |
Transcription Factor AP-1/*metabolism | 2 | 1.0 |
Transcription, Genetic | 11 | 0.0 |
Carrier Proteins/*chemistry/*metabolism | 2 | 4.0 |
Proline/chemistry | 6 | 12.0 |
Tissue Distribution | 10 | 0.0 |
Two-Hybrid System Techniques | 12 | 1.0 |
src-Family Kinases/*metabolism | 7 | 4.0 |
*Cell Transformation, Neoplastic | 11 | 2.0 |
Intramolecular Transferases/metabolism | 3 | 100.0 |
Endothelium, Vascular/*metabolism | 2 | 0.0 |
Kidney | 6 | 1.0 |
Protein Biosynthesis | 12 | 0.0 |
Protein Processing, Post-Translational | 13 | 1.0 |
Proteins/genetics/*physiology | 2 | 1.0 |
RNA, Messenger/biosynthesis | 4 | 0.0 |
Receptors, Growth Factor/metabolism | 4 | 3.0 |
Receptors, Vascular Endothelial Growth Factor | 3 | 0.0 |
Vascular Endothelial Growth Factor A | 4 | 0.0 |
Vascular Endothelial Growth Factors | 4 | 0.0 |
Cloning, Molecular | 35 | 0.0 |
Neoplasm Proteins/*metabolism | 4 | 0.0 |
Nuclear Localization Signal | 2 | 2.0 |
*Repressor Proteins | 3 | 0.0 |
Nerve Growth Factors/pharmacology | 4 | 4.0 |
Receptor Protein-Tyrosine Kinases/genetics/*metabolism | 7 | 5.0 |
*Tyrosine | 8 | 16.0 |
p38 Mitogen-Activated Protein Kinases | 5 | 0.0 |
Fibroblast Growth Factors/metabolism | 2 | 3.0 |
In Situ Hybridization | 2 | 0.0 |
Membrane Proteins/chemistry/genetics/*metabolism | 2 | 3.0 |
Phosphoproteins/chemistry/genetics/*metabolism | 7 | 17.0 |
Receptors, Fibroblast Growth Factor/genetics/metabolism | 3 | 13.0 |
src-Family Kinases/genetics/*metabolism | 3 | 14.0 |
Cell Fractionation | 3 | 1.0 |
Hepatocyte Growth Factor/*metabolism | 4 | 3.0 |
Proteins/genetics/metabolism | 7 | 3.0 |
Proto-Oncogene Protein c-met/metabolism | 5 | 6.0 |
Adult | 4 | 0.0 |
*Antigens, Differentiation | 2 | 2.0 |
Brain/metabolism | 5 | 0.0 |
*Intracellular Signaling Peptides and Proteins | 4 | 0.0 |
*Neural Cell Adhesion Molecule L1 | 2 | 7.0 |
Protein-Tyrosine-Phosphatase/genetics/*metabolism | 4 | 8.0 |
*Receptors, Immunologic | 3 | 1.0 |
*Gene Expression Regulation, Neoplastic | 5 | 0.0 |
Proteins/chemistry | 2 | 4.0 |
Cell Survival/physiology | 2 | 1.0 |
Insulin-Like Growth Factor I/*physiology | 3 | 8.0 |
Receptor, IGF Type 1/metabolism | 2 | 6.0 |
Recombinant Proteins | 3 | 0.0 |
*Cell Cycle Proteins | 19 | 1.0 |
Mutagenesis | 8 | 0.0 |
Protein Structure, Secondary | 4 | 0.0 |
Proteins/*chemistry/genetics | 3 | 14.0 |
1-Phosphatidylinositol 3-Kinase/*metabolism | 14 | 5.0 |
Phosphoproteins/metabolism/*physiology | 3 | 17.0 |
Recombinant Proteins/pharmacology | 14 | 0.0 |
Signal Transduction/drug effects/physiology | 3 | 1.0 |
Killer Cells, Natural/*immunology | 3 | 0.0 |
Lymphocyte Activation/immunology | 2 | 0.0 |
Mice, Transgenic | 8 | 0.0 |
Proto-Oncogene Protein c-met/genetics/*metabolism | 3 | 17.0 |
Amino Acid Substitution | 4 | 0.0 |
Calcium/metabolism | 14 | 0.0 |
DNA-Binding Proteins/genetics/metabolism | 2 | 0.0 |
Membrane Proteins/chemistry/metabolism | 2 | 6.0 |
*Nuclear Proteins | 10 | 0.0 |
Phosphoproteins/*chemistry/*metabolism | 2 | 11.0 |
Recombinant Proteins/chemistry/metabolism | 4 | 0.0 |
T-Lymphocytes/immunology/*physiology | 3 | 5.0 |
Transcription Factors/genetics/metabolism | 2 | 0.0 |
Retroviridae Proteins, Oncogenic/*metabolism | 5 | 17.0 |
Signal Transduction/drug effects/*physiology | 10 | 4.0 |
rhoA GTP-Binding Protein/metabolism | 2 | 2.0 |
RNA, Messenger/metabolism | 10 | 0.0 |
Receptors, Platelet-Derived Growth Factor/metabolism | 2 | 4.0 |
Alkyl and Aryl Transferases/antagonists & inhibitors | 2 | 28.0 |
Neoplasms/*drug therapy/pathology | 2 | 11.0 |
Protein Kinase C/antagonists & inhibitors | 4 | 3.0 |
Proto-Oncogene Proteins c-raf/antagonists & inhibitors | 2 | 40.0 |
Hydrolysis | 4 | 0.0 |
Protein Conformation | 13 | 0.0 |
Luciferases/metabolism | 4 | 0.0 |
Mitogen-Activated Protein Kinases | 2 | 18.0 |
Proline/chemistry/metabolism | 3 | 75.0 |
Protein Kinase C/metabolism | 7 | 1.0 |
Receptors, Growth Factor/*metabolism | 2 | 1.0 |
Epidermal Growth Factor/*pharmacology | 16 | 1.0 |
Membrane Proteins/analysis | 2 | 1.0 |
Microscopy, Electron | 3 | 0.0 |
Receptor, Epidermal Growth Factor/analysis/*metabolism | 2 | 10.0 |
Fibroblast Growth Factor 2/*pharmacology | 3 | 2.0 |
MAP Kinase Signaling System/drug effects/*physiology | 2 | 5.0 |
Xenopus laevis | 2 | 0.0 |
*Drosophila Proteins | 12 | 1.0 |
Membrane Proteins/metabolism/*physiology | 2 | 6.0 |
Multiple Endocrine Neoplasia Type 2a/genetics | 3 | 10.0 |
*Nerve Growth Factors | 2 | 1.0 |
Protein-Tyrosine-Phosphatase/metabolism | 21 | 16.0 |
Receptor Protein-Tyrosine Kinases/metabolism/*physiology | 2 | 13.0 |
DNA/chemistry/genetics | 2 | 0.0 |
Polymorphism, Genetic | 2 | 0.0 |
Phosphoproteins/genetics/*metabolism/physiology | 2 | 33.0 |
Protein-Serine-Threonine Kinases/genetics/metabolism | 2 | 1.0 |
Proto-Oncogene Proteins/genetics/metabolism | 2 | 1.0 |
Receptors, Fibroblast Growth Factor/genetics/*metabolism | 2 | 5.0 |
*Protein-Tyrosine Kinase | 4 | 1.0 |
Interleukin-3/*pharmacology | 3 | 2.0 |
MAP Kinase Kinase 2 | 2 | 4.0 |
Mitogen-Activated Protein Kinase Kinases/metabolism | 3 | 1.0 |
Phosphoproteins/*physiology | 7 | 8.0 |
Protein-Serine-Threonine Kinases/metabolism | 18 | 2.0 |
Protein-Tyrosine-Phosphatase/*physiology | 4 | 14.0 |
Sequence Deletion | 10 | 0.0 |
Antioxidants | 2 | 6.0 |
*Diet | 2 | 0.0 |
Dietary Carbohydrates | 2 | 8.0 |
Fruit | 2 | 7.0 |
Gallbladder Neoplasms/*epidemiology/prevention & control | 2 | 25.0 |
India/epidemiology | 2 | 2.0 |
Obesity/complications | 2 | 4.0 |
Vegetables | 2 | 8.0 |
World Health | 2 | 3.0 |
Consensus Sequence | 7 | 0.0 |
Oligodeoxyribonucleotides | 5 | 0.0 |
Spectrometry, Fluorescence | 3 | 0.0 |
Tryptophan/chemistry | 2 | 5.0 |
Interleukin-2/pharmacology | 2 | 0.0 |
Mitogen-Activated Protein Kinases/*physiology | 2 | 2.0 |
Receptors, Antigen, T-Cell/physiology | 3 | 2.0 |
Tetradecanoylphorbol Acetate/pharmacology | 14 | 0.0 |
Carrier Proteins/chemistry/*metabolism | 2 | 2.0 |
DNA-Binding Proteins/metabolism | 11 | 0.0 |
Hematopoietic Stem Cells/*physiology | 2 | 1.0 |
T-Lymphocytes/drug effects/*metabolism | 2 | 4.0 |
Transcription Factors/metabolism | 6 | 0.0 |
Carrier Proteins/*physiology | 4 | 1.0 |
Cell Transformation, Neoplastic | 6 | 1.0 |
Proteasome Endopeptidase Complex | 2 | 0.0 |
Protein-Tyrosine Kinase/*physiology | 6 | 4.0 |
Phosphoric Monoester Hydrolases/metabolism | 4 | 5.0 |
Membrane Proteins/metabolism | 15 | 2.0 |
Phosphoproteins/*genetics | 2 | 0.0 |
T-Lymphocytes/*metabolism | 12 | 3.0 |
Tyrosine/chemistry/*metabolism | 2 | 20.0 |
Membrane Microdomains/metabolism | 2 | 6.0 |
Nuclear Proteins/metabolism | 10 | 1.0 |
Oncogene Proteins/metabolism | 6 | 7.0 |
Vanadates/pharmacology | 9 | 6.0 |
Collagen/metabolism | 4 | 1.0 |
Extracellular Matrix/metabolism | 2 | 1.0 |
Membrane Proteins/chemistry/*metabolism | 4 | 7.0 |
Phosphoproteins/chemistry/*metabolism | 7 | 12.0 |
Cell Division | 37 | 0.0 |
Interleukin-2/biosynthesis | 2 | 0.0 |
*Point Mutation | 4 | 0.0 |
Apoptosis | 8 | 0.0 |
ras Proteins/genetics/metabolism | 5 | 20.0 |
Receptor, Epidermal Growth Factor/metabolism | 39 | 7.0 |
Vitamin K/*pharmacology | 2 | 50.0 |
Nuclear Proteins/*metabolism | 3 | 0.0 |
Protein-Tyrosine Kinase/physiology | 7 | 5.0 |
Chromatography, Affinity | 2 | 0.0 |
Receptor, erbB-2/*metabolism | 7 | 4.0 |
Terminal Repeat Sequences | 2 | 6.0 |
Trans-Activation (Genetics) | 7 | 0.0 |
Trans-Activators/metabolism | 6 | 0.0 |
Protein Binding/immunology | 2 | 1.0 |
Computer Simulation | 2 | 0.0 |
Magnetic Resonance Spectroscopy | 3 | 0.0 |
Proline/genetics/metabolism | 2 | 22.0 |
Proteins/*chemistry/genetics/*metabolism | 3 | 10.0 |
Solutions | 2 | 1.0 |
*Antigens, CD | 2 | 0.0 |
Membrane Glycoproteins/*physiology | 3 | 1.0 |
Phospholipase C/physiology | 4 | 14.0 |
Proteins | 3 | 5.0 |
Proto-Oncogene Proteins c-fos/genetics | 3 | 5.0 |
Yeasts | 2 | 2.0 |
Saccharomyces cerevisiae/genetics | 5 | 1.0 |
src Homology Domains/genetics/*physiology | 3 | 23.0 |
Hepatocyte Growth Factor/pharmacology | 3 | 4.0 |
Microfilament Proteins/metabolism | 2 | 2.0 |
*Muscle Proteins | 2 | 0.0 |
Proto-Oncogene Protein c-met/*metabolism | 5 | 8.0 |
*Proteins | 3 | 0.0 |
Recombinant Fusion Proteins/chemistry/metabolism | 7 | 3.0 |
*Drug Design | 2 | 2.0 |
Structure-Activity Relationship | 25 | 0.0 |
Receptor Protein-Tyrosine Kinases/*metabolism | 20 | 7.0 |
Middle Aged | 6 | 0.0 |
Insulin/*physiology | 5 | 11.0 |
Receptor, Insulin/*physiology | 4 | 44.0 |
Cross-Linking Reagents/pharmacology | 2 | 1.0 |
Octoxynol/pharmacology | 3 | 5.0 |
Protein Kinases/metabolism | 6 | 1.0 |
Phosphoric Monoester Hydrolases/*metabolism | 11 | 11.0 |
Proto-Oncogene Protein c-kit/metabolism | 3 | 6.0 |
Receptor, Insulin/metabolism | 7 | 8.0 |
Receptor, Macrophage Colony-Stimulating Factor/metabolism | 2 | 25.0 |
Conserved Sequence | 2 | 0.0 |
Proteins/*chemistry | 5 | 5.0 |
Receptor, Epidermal Growth Factor/*chemistry | 2 | 13.0 |
Breast Neoplasms/*metabolism | 7 | 2.0 |
Up-Regulation | 6 | 0.0 |
1-Phosphatidylinositol 3-Kinase/*physiology | 2 | 3.0 |
Cell Transformation, Neoplastic/*genetics | 5 | 2.0 |
DNA, Complementary/genetics | 8 | 0.0 |
*Gene Expression Regulation | 2 | 0.0 |
Isoenzymes/physiology | 4 | 8.0 |
MAP Kinase Signaling System/*physiology | 2 | 2.0 |
Neoplasm Transplantation | 3 | 0.0 |
Oncogenes | 3 | 1.0 |
Thyroid Neoplasms/genetics | 2 | 7.0 |
Apoptosis/genetics | 2 | 0.0 |
*Protein Biosynthesis | 4 | 0.0 |
Proteins/genetics | 2 | 0.0 |
Androstadienes/pharmacology | 5 | 1.0 |
Potassium Channels/metabolism | 2 | 5.0 |
*Protein Processing, Post-Translational | 2 | 0.0 |
Proto-Oncogene Protein p21(ras)/*physiology | 3 | 17.0 |
Cytochalasin D/pharmacology | 4 | 5.0 |
Protein Kinases/*metabolism | 7 | 2.0 |
Mitogens/metabolism | 4 | 16.0 |
Erythropoietin/*metabolism | 2 | 4.0 |
Indoles/pharmacology | 2 | 0.0 |
Maleimides/pharmacology | 2 | 2.0 |
Protein Kinase C/antagonists & inhibitors/*metabolism | 3 | 3.0 |
Protein Kinase C/*metabolism | 2 | 0.0 |
Enzyme Precursors/metabolism | 7 | 5.0 |
Receptors, IgE/*immunology/metabolism | 2 | 66.0 |
Blood Platelets/*drug effects/metabolism | 2 | 5.0 |
Integrins/*metabolism | 8 | 5.0 |
Phospholipase C/*metabolism | 4 | 3.0 |
Receptors, Antigen, T-Cell/*physiology | 14 | 8.0 |
Protein Kinase C/physiology | 3 | 1.0 |
Proto-Oncogene Proteins c-raf/physiology | 2 | 25.0 |
Stem Cell Factor/*pharmacology | 2 | 3.0 |
Molecular Structure | 5 | 0.0 |
src Homology Domains/*drug effects | 3 | 60.0 |
Transcription Factor AP-1/metabolism | 3 | 1.0 |
Antigens, CD/*metabolism | 5 | 0.0 |
B-Lymphocytes/*metabolism | 6 | 3.0 |
Phosphoric Monoester Hydrolases/genetics/*metabolism | 4 | 9.0 |
Receptor Aggregation | 2 | 2.0 |
Receptors, Antigen, B-Cell/metabolism | 2 | 4.0 |
Receptors, IgG/*metabolism | 6 | 9.0 |
Angiotensin II/*physiology | 2 | 5.0 |
Calcium/physiology | 4 | 1.0 |
Protein Kinases/physiology | 3 | 6.0 |
Proteins/chemistry/metabolism | 4 | 12.0 |
Cattle | 5 | 0.0 |
Chromosome Mapping | 5 | 0.0 |
DNA, Complementary | 10 | 0.0 |
Catalysis | 3 | 0.0 |
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/physiology | 2 | 14.0 |
Imidazoles/pharmacology | 2 | 0.0 |
Macrophages | 2 | 2.0 |
*Cytoskeletal Proteins | 2 | 1.0 |
Carcinoma, Hepatocellular | 4 | 1.0 |
Receptors, Cytokine/*physiology | 3 | 11.0 |
Fibrinogen/metabolism | 2 | 0.0 |
Oligopeptides/pharmacology | 2 | 1.0 |
Platelet Glycoprotein GPIIb-IIIa Complex/*metabolism | 2 | 6.0 |
B-Lymphocytes/*physiology | 5 | 3.0 |
Phosphoric Monoester Hydrolases/*chemistry/metabolism | 2 | 28.0 |
Protein Structure, Quaternary | 2 | 1.0 |
Enzyme Precursors/*metabolism | 3 | 2.0 |
Lymphoma, B-Cell | 2 | 5.0 |
T-Lymphocytes/physiology | 3 | 2.0 |
Receptors, IgE/*physiology | 2 | 14.0 |
Lymphocyte Activation/physiology | 2 | 2.0 |
Membrane Proteins/*physiology | 5 | 3.0 |
T-Lymphocytes/*physiology | 5 | 1.0 |
*Milk Proteins | 2 | 0.0 |
Phosphotyrosine/*chemistry | 3 | 42.0 |
Receptor, erbB-2/metabolism | 4 | 2.0 |
Phosphopeptides/metabolism | 4 | 13.0 |
GTP-Binding Proteins/physiology | 2 | 3.0 |
Receptors, Interleukin/*physiology | 3 | 12.0 |
Chick Embryo | 3 | 0.0 |
*Genes, ras | 6 | 2.0 |
Receptor, Epidermal Growth Factor/*genetics | 2 | 0.0 |
Cardiomegaly/*physiopathology | 2 | 33.0 |
Erythropoietin/pharmacology | 3 | 2.0 |
Phosphotyrosine/analysis | 2 | 3.0 |
Tyrosine/genetics/metabolism | 4 | 21.0 |
Detergents/pharmacology | 3 | 2.0 |
Cell Adhesion | 9 | 0.0 |
Receptor, Epidermal Growth Factor/drug effects/*metabolism | 2 | 3.0 |
Cell Movement/*physiology | 2 | 0.0 |
Cell Survival/drug effects/physiology | 2 | 2.0 |
Fibroblast Growth Factor 2/pharmacology | 2 | 0.0 |
Membrane Glycoproteins/*metabolism | 2 | 0.0 |
Breast Neoplasms/*drug therapy/*metabolism | 2 | 10.0 |
Cytoskeleton/*metabolism | 3 | 2.0 |
Phosphoproteins/chemistry | 3 | 13.0 |
Tyrosine/*chemistry | 3 | 23.0 |
Cell Compartmentation | 4 | 1.0 |
Guanosine Diphosphate/metabolism | 6 | 5.0 |
NADPH Oxidase/*metabolism | 2 | 4.0 |
Receptors, IgG | 2 | 1.0 |
Receptors, Antigen, B-Cell/*metabolism | 6 | 7.0 |
Genetic Vectors | 3 | 0.0 |
Morphogenesis | 2 | 0.0 |
Carrier Proteins/chemistry/genetics/*metabolism | 5 | 3.0 |
HL-60 Cells | 3 | 0.0 |
Protein-Serine-Threonine Kinases/genetics/*metabolism | 2 | 0.0 |
src Homology Domains/*genetics | 2 | 6.0 |
Insulin-Like Growth Factor I/*pharmacology | 4 | 2.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism | 41 | 12.0 |
Thymidine/metabolism | 4 | 1.0 |
Proteins/chemistry/*metabolism | 13 | 14.0 |
Models, Genetic | 3 | 0.0 |
Oncogene Protein pp60(v-src)/*metabolism | 2 | 16.0 |
Interleukin-2/*genetics | 2 | 3.0 |
Receptors, Antigen, T-Cell/*immunology | 2 | 1.0 |
Transcription Factors/*metabolism | 2 | 0.0 |
Receptors, Fc/*physiology | 2 | 5.0 |
GTP-Binding Proteins/metabolism | 4 | 1.0 |
Peptides/*pharmacology | 3 | 1.0 |
Proteins/*antagonists & inhibitors/metabolism | 2 | 40.0 |
rac GTP-Binding Proteins | 2 | 1.0 |
Antigens, Polyomavirus Transforming/genetics/metabolism | 2 | 22.0 |
Lymphocyte Activation/*physiology | 2 | 2.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/*metabolism | 26 | 8.0 |
*Mitogen-Activated Protein Kinases | 19 | 5.0 |
Receptor, Epidermal Growth Factor/genetics | 2 | 1.0 |
Sequence Analysis | 2 | 0.0 |
Tyrosine | 7 | 6.0 |
Molecular Mimicry | 4 | 5.0 |
Receptor, Epidermal Growth Factor/chemistry | 2 | 66.0 |
Models, Immunological | 2 | 0.0 |
Son of Sevenless Proteins | 43 | 81.0 |
Interleukin-3/pharmacology | 4 | 1.0 |
Proto-Oncogene Protein c-kit/genetics/*metabolism | 2 | 18.0 |
Receptor Protein-Tyrosine Kinases/genetics/metabolism | 2 | 3.0 |
Stem Cell Factor | 4 | 4.0 |
Guanine Nucleotide Exchange Factors | 25 | 28.0 |
Isoenzymes/*metabolism | 3 | 1.0 |
Cell Differentiation/drug effects/physiology | 2 | 2.0 |
Membrane Proteins/genetics/metabolism | 2 | 1.0 |
Phosphoproteins/genetics/metabolism | 2 | 2.0 |
Recombinant Proteins/genetics/metabolism | 4 | 0.0 |
Mutation/genetics | 5 | 0.0 |
Receptors, Transferrin/metabolism | 2 | 2.0 |
Integrins/physiology | 2 | 2.0 |
*Gene Expression Regulation, Enzymologic | 2 | 0.0 |
Cell Membrane/physiology/ultrastructure | 2 | 8.0 |
Fetus | 2 | 0.0 |
*Transcription, Genetic | 2 | 0.0 |
Biological Transport | 8 | 0.0 |
Cyclic AMP/metabolism | 2 | 0.0 |
Endothelium, Vascular/drug effects/*metabolism | 2 | 2.0 |
GTPase-Activating Proteins | 10 | 6.0 |
ras GTPase-Activating Proteins | 8 | 7.0 |
Mitogen-Activated Protein Kinase 1 | 27 | 20.0 |
Viral Nonstructural Proteins/genetics/*metabolism | 3 | 33.0 |
Viral Proteins/metabolism | 2 | 2.0 |
Interleukin-2/genetics | 2 | 2.0 |
Carcinoma, Hepatocellular/metabolism | 2 | 2.0 |
Receptor, Insulin/genetics/*metabolism | 2 | 15.0 |
Carrier Proteins/chemistry/metabolism | 2 | 6.0 |
Gene Expression Regulation/genetics | 3 | 1.0 |
Trans-Activation (Genetics)/genetics | 3 | 3.0 |
Surface Plasmon Resonance | 2 | 1.0 |
Cytosol/metabolism | 3 | 0.0 |
Genes, Dominant | 5 | 0.0 |
RNA, Small Interfering/metabolism | 3 | 1.0 |
Fibronectins/metabolism | 3 | 1.0 |
Quinones/pharmacology | 2 | 1.0 |
Bone Marrow Cells | 2 | 0.0 |
Phosphoproteins/metabolism/physiology | 2 | 100.0 |
Proteins/metabolism/physiology | 3 | 27.0 |
Receptor, Epidermal Growth Factor/metabolism/physiology | 2 | 20.0 |
Receptors, IgG/*physiology | 6 | 20.0 |
src-Family Kinases/*physiology | 2 | 5.0 |
Phosphoproteins/isolation & purification/metabolism | 3 | 8.0 |
Erythropoietin, Recombinant/*pharmacology | 2 | 8.0 |
Leukemia | 2 | 2.0 |
T-Lymphocytes | 3 | 1.0 |
Cell Adhesion Molecules/*metabolism | 4 | 1.0 |
Genes, Reporter/genetics | 2 | 0.0 |
Protein Binding/genetics | 4 | 1.0 |
Membrane Proteins/*metabolism | 25 | 5.0 |
*Cell Differentiation | 3 | 1.0 |
DNA, Complementary/chemistry | 2 | 1.0 |
*Gene Expression | 2 | 0.0 |
Hematopoietic Stem Cells/metabolism | 3 | 2.0 |
Leukemia, Myeloid | 3 | 8.0 |
RNA, Messenger/genetics | 3 | 0.0 |
Sequence Analysis, DNA | 3 | 0.0 |
Carbachol/pharmacology | 2 | 2.0 |
Cell Adhesion Molecules/metabolism | 2 | 0.0 |
Receptors, Muscarinic/*metabolism | 3 | 8.0 |
Retroviridae Proteins, Oncogenic/metabolism | 3 | 8.0 |
Oligonucleotides, Antisense/pharmacology | 5 | 1.0 |
Fibroblasts/cytology | 3 | 1.0 |
Receptor, trkA | 3 | 5.0 |
Receptors, Nerve Growth Factor/*metabolism | 2 | 4.0 |
Interleukin-4/*physiology | 2 | 4.0 |
src Homology Domains/*immunology | 2 | 14.0 |
Inositol Phosphates/physiology | 2 | 33.0 |
Receptor, Insulin/genetics/physiology | 2 | 50.0 |
Collagen | 2 | 1.0 |
Insulin/*metabolism | 5 | 6.0 |
Proteins/*genetics/metabolism | 3 | 1.0 |
Signal Transduction/*genetics | 6 | 4.0 |
T-Lymphocytes/immunology/metabolism | 2 | 1.0 |
1-Phosphatidylinositol 3-Kinase/physiology | 3 | 2.0 |
Cell Cycle | 4 | 0.0 |
Neurons/metabolism | 2 | 0.0 |
ras Guanine Nucleotide Exchange Factors | 21 | 39.0 |
Receptor, trkB | 2 | 28.0 |
Neurites/physiology | 2 | 10.0 |
Pyrazoles/pharmacology | 2 | 4.0 |
Pyrimidines/pharmacology | 2 | 1.0 |
Saccharomyces cerevisiae | 6 | 2.0 |
Transcription Factors/physiology | 2 | 0.0 |
Neuroblastoma/*metabolism/pathology | 2 | 5.0 |
Receptor, Epidermal Growth Factor | 2 | 0.0 |
*Fibroblast Growth Factors | 2 | 2.0 |
Gene Expression Regulation, Developmental | 2 | 0.0 |
*src Homology Domains/genetics | 2 | 33.0 |
Liver Neoplasms | 3 | 1.0 |
*Mitogen-Activated Protein Kinase Kinases | 6 | 6.0 |
Receptors, Retinoic Acid/metabolism | 2 | 2.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/physiology | 3 | 8.0 |
Amino Acid Substitution/genetics | 3 | 1.0 |
Phenylalanine | 4 | 15.0 |
Killer Cells, Natural/*metabolism | 2 | 3.0 |
Genes, ras/genetics | 2 | 1.0 |
Leukemia, Myeloid, Chronic/metabolism | 2 | 22.0 |
GTP-Binding Proteins/*physiology | 2 | 1.0 |
1-Phosphatidylinositol 3-Kinase/antagonists & inhibitors/*metabolism | 2 | 3.0 |
*Phosphoproteins | 2 | 1.0 |
Antibodies/immunology | 2 | 0.0 |
T-Lymphocytes/immunology/*metabolism | 2 | 2.0 |
Growth Substances/*pharmacology | 4 | 1.0 |
Hepatocyte Growth Factor/*pharmacology | 2 | 1.0 |
Proto-Oncogene Protein p21(ras)/*metabolism | 15 | 34.0 |
Macrophage Colony-Stimulating Factor/*pharmacology | 4 | 10.0 |
Lipids/metabolism | 2 | 0.0 |
ras Proteins/physiology | 2 | 6.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism/*physiology | 2 | 22.0 |
Transfection/genetics | 2 | 1.0 |
Hematopoietic Stem Cells/cytology/*metabolism | 2 | 8.0 |
Growth Substances/metabolism | 2 | 1.0 |
Microscopy, Immunoelectron | 2 | 0.0 |
Hepacivirus/*physiology | 2 | 9.0 |
Microscopy, Confocal | 4 | 0.0 |
Promoter Regions (Genetics)/genetics | 2 | 0.0 |
Simian virus 40/genetics | 2 | 1.0 |
Membrane Proteins/physiology | 4 | 4.0 |
Recombinant Proteins/immunology | 2 | 0.0 |
Arginine/genetics | 2 | 1.0 |
Receptor-CD3 Complex, Antigen, T-Cell/*physiology | 2 | 9.0 |
Cell-Free System | 2 | 0.0 |
Phosphoproteins/isolation & purification/*metabolism | 6 | 18.0 |
Proteins/isolation & purification/*metabolism | 9 | 29.0 |
Proto-Oncogene Protein pp60(c-src)/*metabolism | 5 | 12.0 |
Receptor, Epidermal Growth Factor/genetics/*metabolism | 8 | 5.0 |
Receptor, erbB-3 | 3 | 3.0 |
Nerve Tissue Proteins/*physiology | 2 | 3.0 |
Receptors, Serotonin, 5-HT1 | 2 | 12.0 |
Chimeric Proteins/genetics/metabolism | 2 | 2.0 |
Human Growth Hormone/*pharmacology | 2 | 5.0 |
Fungal Proteins/*metabolism | 3 | 3.0 |
GTP-Binding Proteins/*metabolism | 7 | 1.0 |
*Oncogenes | 2 | 0.0 |
Transplantation, Heterologous | 2 | 0.0 |
Peptide Fragments/chemistry/metabolism | 2 | 1.0 |
Peptides/chemistry/*metabolism | 3 | 17.0 |
Phosphorus Radioisotopes/diagnostic use | 2 | 11.0 |
Proteins/analysis/*metabolism | 2 | 14.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/antagonists & inhibitors | 3 | 13.0 |
Genes, ras | 4 | 1.0 |
Receptor, Epidermal Growth Factor/biosynthesis | 3 | 6.0 |
Fibroblast Growth Factors/pharmacology | 2 | 3.0 |
Platelet-Derived Growth Factor/pharmacology | 8 | 4.0 |
Dynamin I | 2 | 20.0 |
Thermodynamics | 3 | 0.0 |
Proteins/genetics/*metabolism/physiology | 2 | 20.0 |
Genes, fos | 3 | 2.0 |
Receptor Protein-Tyrosine Kinases/*physiology | 3 | 4.0 |
Vascular Endothelial Growth Factor Receptor-3 | 2 | 3.0 |
Phospholipase C/isolation & purification/*metabolism | 2 | 50.0 |
Phosphotyrosine | 22 | 8.0 |
Proto-Oncogene Proteins/isolation & purification/*metabolism | 3 | 20.0 |
Gastrins/*pharmacology | 2 | 12.0 |
Gene Expression Regulation, Neoplastic/drug effects | 2 | 0.0 |
Luciferases/biosynthesis | 2 | 2.0 |
Myelin Basic Proteins/metabolism | 2 | 3.0 |
Recombinant Fusion Proteins/biosynthesis | 3 | 0.0 |
Proto-Oncogene Proteins c-raf | 9 | 8.0 |
Glutathione Transferase | 3 | 7.0 |
Recombinant Proteins/biosynthesis/isolation & purification/metabolism | 4 | 6.0 |
1-Phosphatidylinositol 3-Kinase | 24 | 16.0 |
Neurofibromin 1 | 2 | 1.0 |
Pertussis Toxin | 3 | 1.0 |
Phosphotransferases (Alcohol Group Acceptor)/metabolism | 15 | 22.0 |
Virulence Factors, Bordetella/pharmacology | 3 | 1.0 |
Antigens, CD45/*physiology | 2 | 16.0 |
Lymphocyte Specific Protein Tyrosine Kinase p56(lck) | 6 | 2.0 |
Nerve Tissue Proteins/*metabolism | 2 | 0.0 |
Prolactin/*pharmacology | 2 | 2.0 |
*Mitosis | 2 | 1.0 |
Hematopoietic Stem Cells/*metabolism | 2 | 1.0 |
Phosphotransferases (Alcohol Group Acceptor)/*metabolism | 10 | 12.0 |
Phosphopeptides/*metabolism | 2 | 20.0 |
DNA Primers/genetics | 3 | 0.0 |
Granulocyte-Macrophage Colony-Stimulating Factor/pharmacology | 3 | 0.0 |
Protein-Tyrosine Kinase/*biosynthesis | 2 | 8.0 |
Proto-Oncogene Protein c-met | 4 | 3.0 |
Receptor, Epidermal Growth Factor/genetics/metabolism | 4 | 7.0 |
Integrin alpha6beta4 | 2 | 10.0 |
*MAP Kinase Kinase Kinases | 2 | 15.0 |
Erythropoietin/*pharmacology | 3 | 2.0 |
Interleukin-6/*physiology | 2 | 2.0 |
Calpain/metabolism | 2 | 8.0 |
Protein Processing, Post-Translational/*drug effects | 3 | 5.0 |
Thrombopoietin/*pharmacology | 3 | 3.0 |
Mitosis | 2 | 0.0 |
Receptor, Insulin/chemistry/*metabolism | 2 | 50.0 |
Caenorhabditis elegans/genetics | 4 | 5.0 |
Proto-Oncogenes | 4 | 2.0 |
Clone Cells | 2 | 0.0 |
Growth Substances/pharmacology | 2 | 1.0 |
Mitogen-Activated Protein Kinase Kinases | 4 | 10.0 |
Plasmids | 2 | 0.0 |
Protein-Tyrosine Kinase/isolation & purification/*metabolism | 2 | 10.0 |
Proteins/isolation & purification/metabolism | 3 | 27.0 |
Receptors, Nerve Growth Factor/metabolism | 2 | 5.0 |
Nerve Tissue Proteins/metabolism | 3 | 1.0 |
Fibroblasts/cytology/*metabolism | 2 | 5.0 |
Receptor, Insulin/genetics/metabolism | 3 | 27.0 |
Receptors, IgE/*metabolism | 2 | 5.0 |
Muscle, Smooth, Vascular/*physiology | 2 | 11.0 |
Mitosis/drug effects | 3 | 2.0 |
Proto-Oncogene Protein p21(ras)/metabolism | 7 | 8.0 |
*Neoplasm Proteins | 2 | 0.0 |
Fusion Proteins, bcr-abl/*physiology | 3 | 17.0 |
Kidney/cytology | 2 | 1.0 |
Proteins/metabolism/*physiology | 3 | 6.0 |
Receptors, Cell Surface/*metabolism | 3 | 0.0 |
Antibodies, Monoclonal | 5 | 0.0 |
Receptors, Cell Surface/chemistry/genetics/*physiology | 2 | 28.0 |
Tyrosine/chemistry/metabolism | 3 | 17.0 |
Burkitt Lymphoma/pathology | 2 | 6.0 |
Proteins/chemistry/*physiology | 2 | 9.0 |
src Homology Domains/*physiology | 4 | 19.0 |
Proto-Oncogene Proteins/chemistry/*metabolism | 3 | 5.0 |
Immunoglobulin G | 2 | 1.0 |
Recombinant Proteins/biosynthesis | 2 | 0.0 |
Microinjections | 2 | 0.0 |
Peptide Fragments/chemistry/isolation & purification | 2 | 5.0 |
Phosphopeptides/chemistry/isolation & purification | 4 | 21.0 |
Sequence Tagged Sites | 3 | 1.0 |
Sensitivity and Specificity | 2 | 0.0 |
Major Histocompatibility Complex | 2 | 0.0 |
Granulocyte-Macrophage Colony-Stimulating Factor/*pharmacology | 3 | 1.0 |
Vero Cells | 2 | 0.0 |
Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/*metabolism | 3 | 33.0 |
SOS1 Protein | 3 | 23.0 |
Receptors, Interleukin-4 | 2 | 2.0 |
Cyclization | 3 | 33.0 |
Oligopeptides/*chemistry | 2 | 13.0 |
Bone Marrow/metabolism | 2 | 1.0 |
Glutathione Transferase/biosynthesis | 2 | 6.0 |
Integrin beta4 | 2 | 11.0 |
Spodoptera | 2 | 0.0 |
Protein-Tyrosine-Phosphatase/antagonists & inhibitors/*metabolism | 2 | 25.0 |
Proto-Oncogene Proteins/biosynthesis/chemistry/*metabolism | 2 | 33.0 |
Restriction Mapping | 2 | 0.0 |
Hematopoietic Stem Cells | 2 | 3.0 |
Recombinant Proteins/metabolism/pharmacology | 2 | 1.0 |
Repressor Proteins/*metabolism | 2 | 1.0 |
*Signal Transduction/drug effects | 2 | 2.0 |
1-Phosphatidylinositol 4-Kinase | 2 | 9.0 |
*Neuregulin-1 | 2 | 7.0 |
Protein-Tyrosine Kinase/genetics/metabolism | 2 | 2.0 |
DNA Primers/chemistry | 3 | 0.0 |
B-Lymphocytes | 2 | 1.0 |
Caenorhabditis elegans | 3 | 3.0 |
Recombinant Fusion Proteins/chemistry/genetics/metabolism | 2 | 1.0 |
T-Lymphocytes/*immunology/*metabolism | 2 | 6.0 |
Recombinant Proteins/biosynthesis/chemistry/metabolism | 2 | 2.0 |
Receptor, Epidermal Growth Factor/chemistry/*metabolism | 4 | 11.0 |
Phosphoproteins/*biosynthesis/genetics | 2 | 11.0 |
Cricetulus | 2 | 0.0 |
*src-Family Kinases | 3 | 7.0 |
Gene Rearrangement | 2 | 0.0 |
Interleukin-6/*pharmacology | 2 | 0.0 |
Recombinant Proteins/isolation & purification/metabolism | 2 | 1.0 |
ras-GRF1 | 2 | 11.0 |
Recombinant Proteins/biosynthesis/metabolism | 3 | 1.0 |
Breast Neoplasms | 2 | 0.0 |
Cell Survival/drug effects | 2 | 0.0 |
Genes, abl | 2 | 5.0 |
*Down-Regulation | 2 | 0.0 |
Computer Graphics | 2 | 3.0 |
Phorbol Esters/pharmacology | 2 | 1.0 |
Homeostasis | 2 | 0.0 |
Growth Hormone/*pharmacology | 2 | 2.0 |
Receptor, Epidermal Growth Factor/biosynthesis/*metabolism | 2 | 9.0 |
Tyrosine/analogs & derivatives/metabolism | 8 | 6.0 |
Phosphotransferases/metabolism | 2 | 4.0 |
Drosophila | 2 | 0.0 |
Tyrosine/*analogs & derivatives/metabolism | 5 | 9.0 |
Culture Media, Conditioned | 2 | 0.0 |
Receptors, Platelet-Derived Growth Factor/*metabolism | 2 | 10.0 |
Peptides/chemistry/metabolism | 4 | 8.0 |
Cell Movement/drug effects | 2 | 0.0 |
Thymus Gland/metabolism | 3 | 4.0 |
Recombinant Fusion Proteins/isolation & purification/metabolism | 2 | 2.0 |
Tyrosine/analogs & derivatives/analysis | 2 | 5.0 |
Endocytosis/physiology | 2 | 2.0 |
RNA Interference | 2 | 0.0 |
Glycogen Synthase/metabolism | 2 | 25.0 |
Growth Inhibitors/*pharmacology | 2 | 1.0 |
Hematopoietic Cell Growth Factors/pharmacology | 3 | 3.0 |
Cytokines/*pharmacology | 3 | 0.0 |
Tyrosine/*analogs & derivatives/chemistry/metabolism | 2 | 100.0 |
Antibodies, Monoclonal/*immunology | 2 | 0.0 |
Interleukin-3/physiology | 2 | 6.0 |
Oncogene Protein p21(ras)/*metabolism | 2 | 13.0 |
Databases | 2 | 2.0 |
*Chromosomes, Human, Pair 17 | 2 | 0.0 |
Proto-Oncogene Proteins c-fos/metabolism | 3 | 2.0 |
Guanine Nucleotides/metabolism | 2 | 10.0 |
*Cell Transformation, Viral | 2 | 1.0 |
Receptor, erbB-2 | 2 | 1.0 |
Lymphokines/*pharmacology | 2 | 0.0 |
Antineoplastic Agents/*chemical synthesis/chemistry/pharmacology | 2 | 7.0 |
Receptors, Platelet-Derived Growth Factor/genetics/metabolism | 2 | 28.0 |
Escherichia coli | 2 | 0.0 |
Glycosylation | 3 | 0.0 |
Protein Folding | 2 | 0.0 |
Subcellular Fractions/metabolism | 2 | 0.0 |
Adaptor Proteins, Vesicular Transport/metabolism | 3 | 20.0 |
Endocytosis | 3 | 0.0 |
Peptides/*chemistry | 2 | 4.0 |
Proteins/*antagonists & inhibitors/chemistry/metabolism | 2 | 100.0 |
Adipocytes/metabolism | 2 | 4.0 |
ras Proteins/antagonists & inhibitors | 2 | 50.0 |
Mitogen-Activated Protein Kinase 8 | 2 | 2.0 |
1-Phosphatidylinositol 3-Kinase/analysis | 2 | 40.0 |