MeSH term
Frequency | Condition_Probility | 1-Phosphatidylinositol 3-Kinase/metabolism | 3 | 0.0 |
Animals | 139 | 0.0 |
Gene Expression Regulation/physiology | 2 | 0.0 |
Human Growth Hormone/*physiology | 3 | 33.0 |
Humans | 217 | 0.0 |
Insulin-Like Growth Factor I/physiology | 3 | 9.0 |
Liver/metabolism | 12 | 1.0 |
*Milk Proteins | 18 | 3.0 |
Promoter Regions (Genetics)/genetics | 2 | 0.0 |
Protein-Tyrosine Kinase/physiology | 3 | 2.0 |
*Proto-Oncogene Proteins | 30 | 1.0 |
Receptors, Somatotropin/physiology | 2 | 40.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 26 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 69 | 0.0 |
Sex Characteristics | 2 | 0.0 |
Signal Transduction/*physiology | 8 | 0.0 |
*Adaptor Proteins, Signal Transducing | 2 | 0.0 |
*Adaptor Proteins, Vesicular Transport | 2 | 0.0 |
Dimerization | 13 | 0.0 |
Dose-Response Relationship, Drug | 7 | 0.0 |
Male | 83 | 0.0 |
Mice | 41 | 0.0 |
Phosphoproteins/metabolism | 2 | 0.0 |
Polyethylene Glycols/*pharmacology | 2 | 7.0 |
Prolactin/pharmacology | 4 | 10.0 |
Protein-Tyrosine Kinase/metabolism | 16 | 1.0 |
Proteins/metabolism | 2 | 0.0 |
Signal Transduction/*drug effects | 2 | 0.0 |
Binding Sites | 13 | 0.0 |
DNA/chemistry/genetics | 3 | 0.0 |
*Evolution, Molecular | 5 | 1.0 |
Growth Hormone/*genetics | 2 | 5.0 |
Mutation/*genetics | 7 | 0.0 |
Protein Binding | 12 | 0.0 |
Rats | 42 | 0.0 |
Receptors, Somatotropin/*genetics | 56 | 91.0 |
Selection (Genetics) | 2 | 1.0 |
Sequence Analysis, DNA | 8 | 0.0 |
Species Specificity | 9 | 0.0 |
Variation (Genetics) | 7 | 0.0 |
Adolescent | 18 | 0.0 |
Aged | 17 | 0.0 |
Blotting, Northern | 11 | 0.0 |
Carrier Proteins/blood | 5 | 4.0 |
Female | 79 | 0.0 |
Gene Expression | 13 | 0.0 |
Human Growth Hormone/blood | 2 | 3.0 |
Insulin-Like Growth Factor I/*metabolism | 2 | 1.0 |
Liver Cirrhosis/*metabolism | 2 | 6.0 |
Middle Aged | 31 | 0.0 |
Receptors, Somatotropin/genetics/*metabolism | 10 | 71.0 |
Research Support, Non-U.S. Gov't | 165 | 0.0 |
Carrier Proteins/genetics | 2 | 0.0 |
*Gene Expression | 13 | 1.0 |
RNA, Messenger | 3 | 0.0 |
Rats, Sprague-Dawley | 11 | 0.0 |
Androstadienes/pharmacology | 3 | 1.0 |
CHO Cells | 20 | 0.0 |
Cell Membrane/metabolism | 7 | 0.0 |
Endocytosis | 2 | 0.0 |
Enzyme Inhibitors/pharmacology | 4 | 0.0 |
Hamsters | 24 | 0.0 |
Kinetics | 12 | 0.0 |
Ligands | 3 | 0.0 |
Models, Biological | 5 | 0.0 |
Time Factors | 7 | 0.0 |
Transferrin/metabolism | 2 | 1.0 |
Adult | 36 | 0.0 |
Body Height/*genetics | 4 | 14.0 |
Phylogeny | 5 | 0.0 |
Cattle | 7 | 0.0 |
Insulin-Like Growth Factor Binding Protein 1/genetics | 2 | 22.0 |
Insulin-Like Growth Factor I/genetics | 3 | 14.0 |
Liver/chemistry | 3 | 3.0 |
RNA, Messenger/analysis | 19 | 0.0 |
Receptor, IGF Type 1/genetics | 2 | 22.0 |
Sensitivity and Specificity | 4 | 0.0 |
Sheep | 7 | 1.0 |
Age Determination by Skeleton | 2 | 10.0 |
Body Height | 4 | 2.0 |
Body Mass Index | 3 | 0.0 |
Body Weight | 3 | 0.0 |
Child | 27 | 0.0 |
Child, Preschool | 18 | 0.0 |
Infant | 9 | 0.0 |
Dwarfism, Pituitary/*genetics | 2 | 66.0 |
English Abstract | 4 | 0.0 |
Mutation | 15 | 0.0 |
DNA-Binding Proteins/genetics/metabolism | 2 | 0.0 |
Receptors, Somatotropin/genetics/metabolism | 3 | 50.0 |
*Transcription Factors | 5 | 0.0 |
Body Weight/drug effects | 3 | 1.0 |
Growth Hormone/*physiology | 6 | 23.0 |
Immunoblotting | 4 | 0.0 |
Mice, Transgenic | 4 | 0.0 |
Phosphorylation | 31 | 0.0 |
Precipitin Tests | 5 | 0.0 |
Receptors, Somatotropin/metabolism | 9 | 39.0 |
Tyrosine/metabolism | 7 | 0.0 |
Amino Acid Sequence | 32 | 0.0 |
COS Cells | 12 | 0.0 |
Gene Expression/drug effects | 3 | 0.0 |
Growth Hormone/metabolism | 9 | 20.0 |
Molecular Sequence Data | 52 | 0.0 |
Mutagenesis, Site-Directed | 10 | 0.0 |
Peptide Hydrolases/*metabolism | 4 | 4.0 |
Receptors, Somatotropin/*genetics/*metabolism | 4 | 80.0 |
Structure-Activity Relationship | 9 | 0.0 |
Tetradecanoylphorbol Acetate/pharmacology | 5 | 0.0 |
Transfection | 33 | 0.0 |
Receptors, Somatotropin/antagonists & inhibitors | 3 | 50.0 |
Growth Hormone/physiology | 3 | 30.0 |
Molecular Conformation | 2 | 0.0 |
Receptors, Somatotropin/chemistry/*metabolism | 5 | 83.0 |
Signal Transduction/physiology | 6 | 0.0 |
*Signal Transduction | 9 | 0.0 |
Biological Transport | 2 | 0.0 |
Cell Line | 32 | 0.0 |
Metabolic Clearance Rate | 2 | 0.0 |
Blotting, Western | 11 | 0.0 |
Immunohistochemistry | 12 | 0.0 |
In Situ Hybridization | 7 | 0.0 |
Receptors, Somatotropin/*analysis/genetics | 2 | 100.0 |
Amino Acid Motifs | 3 | 0.0 |
Endocytosis/*physiology | 3 | 2.0 |
Mutagenesis | 4 | 0.0 |
Ubiquitin/*metabolism | 3 | 1.0 |
Aged, 80 and over | 8 | 0.0 |
Comparative Study | 23 | 0.0 |
Gene Expression Regulation/drug effects | 2 | 0.0 |
Human Growth Hormone/blood/*metabolism | 3 | 60.0 |
RNA, Messenger/*biosynthesis | 4 | 1.0 |
Reverse Transcriptase Polymerase Chain Reaction | 17 | 0.0 |
Cercopithecus aethiops | 3 | 0.0 |
In Vitro | 3 | 0.0 |
Gastric Mucosa/metabolism | 2 | 4.0 |
Human Growth Hormone/*blood | 2 | 6.0 |
Radioimmunoassay | 4 | 0.0 |
Receptors, Somatotropin/*metabolism | 14 | 70.0 |
Case-Control Studies | 3 | 0.0 |
Disease Models, Animal | 3 | 0.0 |
Human Growth Hormone/metabolism | 6 | 31.0 |
Insulin-Like Growth Factor I/metabolism | 10 | 5.0 |
Mice, Knockout | 4 | 0.0 |
Hyperplasia | 2 | 0.0 |
Metallothionein/genetics | 2 | 5.0 |
Mice, Inbred Strains | 2 | 0.0 |
Phenotype | 10 | 0.0 |
Reference Values | 8 | 0.0 |
Drug Resistance | 2 | 0.0 |
Eating/drug effects | 2 | 5.0 |
Human Growth Hormone/*pharmacology | 6 | 15.0 |
Protein-Tyrosine Kinase/*metabolism | 9 | 1.0 |
RNA, Messenger/genetics/metabolism | 5 | 0.0 |
Signal Transduction | 16 | 0.0 |
Trans-Activators/*metabolism | 6 | 0.0 |
Pedigree | 10 | 0.0 |
Phosphotyrosine/metabolism | 10 | 2.0 |
Rabbits | 19 | 0.0 |
Receptors, Somatotropin/chemistry/genetics/*metabolism | 2 | 50.0 |
Recombinant Proteins/chemistry/metabolism | 2 | 0.0 |
Signal Transduction/drug effects/*physiology | 2 | 0.0 |
Base Sequence | 44 | 0.0 |
Binding, Competitive | 3 | 0.0 |
Cell Division/drug effects | 5 | 0.0 |
Cloning, Molecular | 11 | 0.0 |
DNA, Complementary/chemistry/genetics | 3 | 0.0 |
Growth Hormone/*metabolism/pharmacology | 3 | 75.0 |
Receptors, Somatotropin/*genetics/metabolism | 8 | 100.0 |
Sequence Alignment | 8 | 0.0 |
Sequence Homology, Amino Acid | 8 | 0.0 |
Tissue Distribution | 10 | 0.0 |
Japan | 2 | 0.0 |
Polymerase Chain Reaction | 27 | 0.0 |
Regression Analysis | 2 | 0.0 |
DNA-Binding Proteins/genetics/*metabolism | 3 | 0.0 |
*Gene Expression Regulation | 4 | 0.0 |
Lipopolysaccharides/pharmacology | 2 | 0.0 |
Liver/*metabolism | 6 | 1.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Trans-Activators/genetics/*metabolism | 3 | 0.0 |
Amino Acids/genetics | 2 | 6.0 |
Primates/*genetics | 2 | 4.0 |
Rats, Wistar | 3 | 0.0 |
Receptors, Somatotropin/*biosynthesis | 4 | 100.0 |
Gene Expression Regulation | 2 | 0.0 |
Organ Specificity | 5 | 0.0 |
Pregnancy | 10 | 0.0 |
DNA-Binding Proteins/*metabolism | 6 | 0.0 |
Dogs | 3 | 0.0 |
Growth Hormone/*pharmacology | 12 | 16.0 |
RNA/analysis | 3 | 1.0 |
Sequence Homology | 2 | 0.0 |
Tumor Cells, Cultured | 10 | 0.0 |
Culture Techniques | 2 | 0.0 |
Densitometry | 3 | 2.0 |
Tetradecanoylphorbol Acetate/*pharmacology | 2 | 0.0 |
3T3 Cells | 9 | 0.0 |
Adipocytes/metabolism | 3 | 7.0 |
Carrier Proteins/*metabolism | 6 | 0.0 |
Down-Regulation | 3 | 0.0 |
Ethylmaleimide/pharmacology | 3 | 5.0 |
MAP Kinase Kinase 1 | 2 | 1.0 |
Human Growth Hormone/pharmacology | 5 | 29.0 |
Receptors, Somatotropin/genetics | 4 | 28.0 |
Cells, Cultured | 9 | 0.0 |
Peptide Fragments/pharmacology | 2 | 0.0 |
Exons | 19 | 0.0 |
Sex Factors | 2 | 0.0 |
DNA Primers | 10 | 0.0 |
HL-60 Cells | 2 | 0.0 |
Receptors, Somatotropin/genetics/*physiology | 4 | 80.0 |
Flavonoids/pharmacology | 2 | 0.0 |
Iodine Radioisotopes/diagnostic use | 3 | 0.0 |
Enzyme Activation | 7 | 0.0 |
Immunosorbent Techniques | 4 | 1.0 |
Mitogen-Activated Protein Kinase 1/metabolism | 2 | 0.0 |
Mitogen-Activated Protein Kinase 3 | 2 | 0.0 |
Mitogen-Activated Protein Kinases/metabolism | 3 | 0.0 |
Acromegaly/*drug therapy | 2 | 11.0 |
Mice, Inbred BALB C | 4 | 0.0 |
Recombinant Proteins/pharmacology | 3 | 0.0 |
Growth Hormone/blood/*metabolism | 2 | 40.0 |
Kidney/metabolism | 3 | 0.0 |
Growth Hormone/*metabolism | 14 | 26.0 |
Receptor, Insulin/metabolism | 2 | 2.0 |
Growth Disorders/drug therapy/*genetics | 3 | 100.0 |
Heterozygote | 7 | 0.0 |
Human Growth Hormone/*therapeutic use | 2 | 9.0 |
Amino Acid Substitution | 3 | 0.0 |
Phenylalanine | 2 | 7.0 |
Receptors, Somatotropin/chemistry/genetics/*physiology | 3 | 100.0 |
Tyrosine | 2 | 1.0 |
src Homology Domains | 3 | 0.0 |
DNA-Binding Proteins/metabolism | 7 | 0.0 |
Enzyme Activation/drug effects | 3 | 0.0 |
Mitogen-Activated Protein Kinases/*metabolism | 2 | 0.0 |
Trans-Activators/metabolism | 7 | 0.0 |
Cytoplasm/chemistry | 2 | 1.0 |
Growth Hormone/pharmacology | 4 | 11.0 |
Liver Neoplasms/*metabolism | 2 | 2.0 |
Receptors, Prolactin/*genetics | 2 | 11.0 |
Adipose Tissue/metabolism | 5 | 4.0 |
Muscle, Skeletal/metabolism | 2 | 1.0 |
Protein Isoforms/genetics | 3 | 1.0 |
RNA, Messenger/*analysis | 2 | 0.0 |
Transcription, Genetic | 11 | 0.0 |
Growth Disorders/*genetics | 11 | 19.0 |
Receptors, Somatotropin/*genetics/physiology | 2 | 66.0 |
Antibodies, Monoclonal | 4 | 0.0 |
Cell Division | 5 | 0.0 |
Chimeric Proteins/metabolism | 2 | 1.0 |
Proto-Oncogene Proteins c-fos/metabolism | 2 | 1.0 |
*Alternative Splicing | 4 | 0.0 |
Growth Disorders/*genetics/metabolism | 2 | 33.0 |
Growth Hormone/blood | 3 | 1.0 |
Insulin-Like Growth Factor Binding Protein 3/blood | 8 | 14.0 |
Insulin-Like Growth Factor I/analysis | 6 | 4.0 |
Polymerase Chain Reaction/methods | 2 | 0.0 |
*Promoter Regions (Genetics) | 3 | 0.0 |
Sequence Deletion | 5 | 0.0 |
Receptors, Prolactin/metabolism | 3 | 18.0 |
Chromatography, Gel | 4 | 0.0 |
Placental Lactogen/*pharmacology | 2 | 66.0 |
Receptors, Prolactin/*chemistry/genetics | 2 | 100.0 |
Receptors, Somatotropin/*chemistry/genetics | 3 | 100.0 |
Surface Plasmon Resonance | 2 | 1.0 |
Trans-Activation (Genetics) | 7 | 0.0 |
Conserved Sequence/genetics | 2 | 1.0 |
Models, Molecular | 4 | 0.0 |
Prolactin/metabolism | 2 | 3.0 |
Protein Conformation | 5 | 0.0 |
Growth Inhibitors/pharmacology | 2 | 1.0 |
*Interleukin-6 | 3 | 0.0 |
Lymphokines/pharmacology | 2 | 1.0 |
Receptor, Epidermal Growth Factor/metabolism | 2 | 0.0 |
Hypophysectomy | 2 | 3.0 |
*Intracellular Signaling Peptides and Proteins | 3 | 0.0 |
Proteins/*metabolism | 2 | 0.0 |
Receptors, Somatotropin/drug effects/*physiology | 3 | 100.0 |
*Repressor Proteins | 4 | 0.0 |
Alternative Splicing | 6 | 0.0 |
Point Mutation | 5 | 0.0 |
Polymorphism, Genetic | 4 | 0.0 |
Genotype | 4 | 0.0 |
*Mutation | 10 | 0.0 |
Chickens | 2 | 0.0 |
Epitopes | 2 | 0.0 |
Protein Structure, Secondary | 2 | 0.0 |
Receptors, Somatotropin/*chemistry/genetics/*metabolism | 4 | 100.0 |
Sequence Homology, Nucleic Acid | 5 | 0.0 |
Carrier Proteins/*genetics | 5 | 0.0 |
Introns | 5 | 0.0 |
Promoter Regions (Genetics) | 3 | 0.0 |
Biopsy | 3 | 0.0 |
Body Composition | 2 | 0.0 |
Carrier Proteins/*analysis | 3 | 3.0 |
Microscopy, Fluorescence | 2 | 0.0 |
Protein Isoforms | 2 | 0.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism | 2 | 0.0 |
Carrier Proteins/*blood | 8 | 3.0 |
Placebos | 2 | 0.0 |
RNA, Messenger/biosynthesis | 4 | 0.0 |
Controlled Clinical Trials | 2 | 8.0 |
Syndrome | 16 | 0.0 |
Growth Disorders/genetics | 3 | 10.0 |
Infant, Newborn | 4 | 0.0 |
Insulin-Like Growth Factor I/*genetics | 2 | 8.0 |
Receptors, Somatotropin/*physiology | 2 | 25.0 |
Cell Line, Transformed | 4 | 0.0 |
Dwarfism/*genetics/metabolism | 2 | 50.0 |
Glycosylation | 2 | 0.0 |
Mutation/genetics | 3 | 0.0 |
Biological Assay | 2 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 3 | 0.0 |
Placenta/*chemistry | 2 | 5.0 |
Dwarfism/*genetics | 4 | 17.0 |
*Heterozygote | 3 | 0.0 |
Culture Media, Serum-Free | 3 | 0.0 |
Homozygote | 8 | 0.0 |
Insulin-Like Growth Factor I/*therapeutic use | 2 | 28.0 |
Recombinant Proteins/therapeutic use | 2 | 0.0 |
Abdomen/*surgery | 2 | 18.0 |
RNA-Directed DNA Polymerase | 3 | 2.0 |
DNA Primers/chemistry | 2 | 0.0 |
Receptors, Somatotropin/*analysis/genetics/metabolism | 2 | 100.0 |
Carrier Proteins/metabolism | 3 | 0.0 |
Drug Resistance/*genetics | 2 | 4.0 |
*Exons | 6 | 1.0 |
Follow-Up Studies | 2 | 0.0 |
*Gene Deletion | 2 | 0.0 |
Human Growth Hormone/*metabolism | 4 | 30.0 |
Proto-Oncogene Proteins c-fos/genetics | 2 | 3.0 |
RNA, Messenger/metabolism | 6 | 0.0 |
DNA, Complementary/analysis | 2 | 0.0 |
*Point Mutation | 3 | 0.0 |
*RNA Splicing | 2 | 0.0 |
Protein-Tyrosine-Phosphatase/*metabolism | 2 | 1.0 |
Radioligand Assay | 2 | 0.0 |
*Phenotype | 3 | 1.0 |
Flow Cytometry | 3 | 0.0 |
Insulin-Like Growth Factor Binding Protein 1/blood | 2 | 10.0 |
*Chromosomes, Human, Pair 5 | 3 | 1.0 |
Linkage (Genetics) | 2 | 0.0 |
Proto-Oncogene Proteins c-raf | 2 | 1.0 |
Immunohistochemistry/methods | 2 | 0.0 |
Insulin-Like Growth Factor I/pharmacology | 2 | 1.0 |
Receptors, Somatotropin/chemistry | 3 | 60.0 |
Culture Media | 2 | 0.0 |
Macaca mulatta | 2 | 0.0 |
Gene Deletion | 3 | 0.0 |
RNA, Messenger/genetics | 4 | 0.0 |
Carcinoma, Hepatocellular/metabolism | 2 | 2.0 |
Blotting, Southern | 6 | 0.0 |
Drug Resistance/genetics | 2 | 1.0 |
RNA, Messenger/*metabolism | 3 | 0.0 |
Receptors, Somatotropin/chemistry/*genetics | 2 | 25.0 |
Solubility | 2 | 0.0 |
Recombinant Proteins | 3 | 0.0 |
DNA | 3 | 0.0 |
Carrier Proteins/blood/*metabolism | 3 | 14.0 |
Growth Hormone/*blood | 2 | 1.0 |
Receptors, Somatotropin/*analysis | 2 | 50.0 |
Open Reading Frames | 2 | 0.0 |
*Polymorphism, Genetic | 2 | 0.0 |
Iodine Radioisotopes | 3 | 0.0 |
Mitogen-Activated Protein Kinase 1 | 2 | 1.0 |
DNA Probes | 2 | 0.0 |
Receptors, Somatotropin/*biosynthesis/genetics | 2 | 100.0 |
Restriction Mapping | 2 | 0.0 |
Phosphotyrosine | 2 | 0.0 |
B-Lymphocytes/metabolism | 2 | 1.0 |
Lymphocytes/*metabolism | 3 | 1.0 |
Receptors, Somatotropin/*biosynthesis/*genetics | 2 | 100.0 |
Skin/metabolism | 2 | 1.0 |
Kidney | 4 | 1.0 |
Phosphoproteins/isolation & purification/*metabolism | 2 | 6.0 |
Cell Nucleus/metabolism | 3 | 0.0 |
Insulin-Like Growth Factor I/*biosynthesis | 2 | 18.0 |
DNA Mutational Analysis | 3 | 0.0 |
Recombinant Proteins/metabolism | 3 | 0.0 |
Macromolecular Substances | 4 | 0.0 |
Isomerism | 2 | 0.0 |
Molecular Probes/genetics | 2 | 2.0 |
Alleles | 4 | 0.0 |
Nucleic Acid Hybridization | 3 | 0.0 |
DNA/genetics | 2 | 0.0 |
Molecular Weight | 3 | 0.0 |
Codon | 3 | 0.0 |
Placenta/*metabolism | 2 | 1.0 |
Plasmids | 3 | 0.0 |
Polymorphism, Single-Stranded Conformational | 2 | 0.0 |
Rats, Inbred Strains | 2 | 0.0 |
Hybrid Cells | 2 | 0.0 |
*Chromosome Mapping | 2 | 0.0 |
Protein Structure, Tertiary | 2 | 0.0 |
Embryo | 2 | 0.0 |
Green Fluorescent Proteins | 2 | 0.0 |
Luminescent Proteins/genetics | 2 | 1.0 |
*Antibodies, Monoclonal | 2 | 0.0 |
Receptors, Somatotropin | 3 | 42.0 |
Metalloendopeptidases/*metabolism | 2 | 2.0 |
Lymphocytes/metabolism | 2 | 0.0 |
Mammary Glands, Animal/metabolism | 2 | 10.0 |
Hypertrophy | 2 | 1.0 |
Proteasome Endopeptidase Complex | 2 | 0.0 |