MeSH term
Frequency | Condition_Probility | Aged | 11 | 0.0 |
Aged, 80 and over | 5 | 0.0 |
Fatal Outcome | 4 | 0.0 |
Female | 96 | 0.0 |
Humans | 223 | 0.0 |
Tomography, X-Ray Computed | 3 | 0.0 |
Acrocephalosyndactylia/*genetics/pathology | 3 | 100.0 |
Child, Preschool | 25 | 0.0 |
DNA/chemistry/genetics | 2 | 0.0 |
DNA Mutational Analysis | 29 | 0.0 |
Family Health | 3 | 0.0 |
In Situ Hybridization, Fluorescence | 6 | 0.0 |
Infant | 29 | 0.0 |
Karyotyping | 2 | 0.0 |
Male | 96 | 0.0 |
Mutation, Missense | 4 | 0.0 |
*Nuclear Proteins | 4 | 0.0 |
Pedigree | 29 | 0.0 |
Phenotype | 34 | 0.0 |
*Protein-Tyrosine Kinase | 23 | 7.0 |
Receptors, Fibroblast Growth Factor/genetics | 18 | 27.0 |
Research Support, Non-U.S. Gov't | 140 | 0.0 |
Transcription Factors/genetics | 4 | 0.0 |
Receptor Protein-Tyrosine Kinases/genetics | 17 | 11.0 |
Research Support, U.S. Gov't, P.H.S. | 67 | 0.0 |
Syndrome | 30 | 1.0 |
Cell Line | 20 | 0.0 |
Disease Progression | 3 | 0.0 |
Down-Regulation | 3 | 0.0 |
RNA, Messenger/metabolism | 8 | 0.0 |
Receptors, Fibroblast Growth Factor/genetics/*metabolism | 7 | 20.0 |
Reference Values | 4 | 0.0 |
Antibodies/diagnostic use | 2 | 4.0 |
Biological Markers/analysis | 2 | 0.0 |
Cell Differentiation | 13 | 0.0 |
Cytoplasm/ultrastructure | 2 | 3.0 |
Dyes/diagnostic use | 2 | 2.0 |
Epithelium/pathology | 2 | 1.0 |
Fibroblast Growth Factor 2/*analysis | 3 | 15.0 |
Immunohistochemistry | 18 | 0.0 |
Receptor Protein-Tyrosine Kinases/*analysis | 3 | 6.0 |
Receptors, Fibroblast Growth Factor/*analysis | 3 | 33.0 |
Statistics, Nonparametric | 2 | 0.0 |
Craniosynostoses/pathology | 2 | 100.0 |
Infant, Newborn | 21 | 0.0 |
*Mutation | 30 | 0.0 |
Receptor Protein-Tyrosine Kinases/*genetics | 64 | 16.0 |
Receptors, Fibroblast Growth Factor/*genetics | 87 | 37.0 |
Adolescent | 17 | 0.0 |
Cells, Cultured | 10 | 0.0 |
Neoplasm Proteins/*genetics | 2 | 0.0 |
Proline | 2 | 3.0 |
Transcription Factors/*genetics | 3 | 0.0 |
DNA-Binding Proteins/genetics | 3 | 0.0 |
Epithelium/embryology | 2 | 11.0 |
Exons/genetics | 10 | 0.0 |
Fibroblast Growth Factors/*genetics | 7 | 14.0 |
Gene Expression Regulation, Developmental/*genetics | 2 | 2.0 |
Image Processing, Computer-Assisted | 2 | 0.0 |
In Situ Hybridization | 11 | 0.0 |
Mutation/genetics | 4 | 0.0 |
Palate/*embryology | 2 | 50.0 |
Protein Isoforms/genetics | 2 | 0.0 |
Serine/genetics | 4 | 4.0 |
Signal Transduction/genetics | 3 | 1.0 |
Transforming Growth Factor beta/*genetics | 2 | 2.0 |
Tryptophan/genetics | 3 | 6.0 |
Abnormalities, Multiple/*genetics | 6 | 1.0 |
Amino Acid Substitution | 11 | 0.0 |
*Mutation, Missense | 5 | 0.0 |
Taiwan | 3 | 1.0 |
English Abstract | 10 | 0.0 |
Fibroblast Growth Factors/pharmacology | 2 | 3.0 |
Neoplasm Invasiveness | 2 | 0.0 |
Signal Transduction | 12 | 0.0 |
Adult | 36 | 0.0 |
Gene Expression Profiling | 2 | 0.0 |
Oligonucleotide Array Sequence Analysis | 3 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 12 | 0.0 |
Vascular Endothelial Growth Factor A | 2 | 0.0 |
Vascular Endothelial Growth Factors | 2 | 0.0 |
Microscopy, Immunoelectron | 2 | 0.0 |
RNA, Messenger/genetics/metabolism | 2 | 0.0 |
Receptor Protein-Tyrosine Kinases/*genetics/*metabolism | 2 | 14.0 |
Receptors, Fibroblast Growth Factor/*genetics/*metabolism | 4 | 23.0 |
Polymorphism, Single-Stranded Conformational | 12 | 0.0 |
Pregnancy | 10 | 0.0 |
Animals | 73 | 0.0 |
Fibroblast Growth Factors/metabolism | 6 | 11.0 |
Mice | 45 | 0.0 |
Mice, Nude | 3 | 0.0 |
Proto-Oncogene Proteins/metabolism | 2 | 0.0 |
Receptors, Fibroblast Growth Factor/metabolism | 3 | 6.0 |
Recombinant Proteins/metabolism | 2 | 0.0 |
Stem Cells/physiology | 2 | 3.0 |
Transcription Factors/genetics/*metabolism | 2 | 0.0 |
*Transforming Growth Factor beta | 2 | 1.0 |
Up-Regulation | 3 | 0.0 |
Alleles | 5 | 0.0 |
Alternative Splicing/genetics | 2 | 1.0 |
Base Sequence | 57 | 0.0 |
Exons/*genetics | 2 | 0.0 |
Genome | 2 | 0.0 |
Introns/genetics | 3 | 0.0 |
Acrocephalosyndactylia/*genetics | 19 | 86.0 |
Genotype | 10 | 0.0 |
Acrocephalosyndactylia/*genetics/physiopathology | 2 | 100.0 |
*Alternative Splicing | 10 | 1.0 |
*Exons | 4 | 1.0 |
*Gene Deletion | 2 | 0.0 |
*Point Mutation | 21 | 1.0 |
Amino Acid Sequence | 46 | 0.0 |
Child | 19 | 0.0 |
Cohort Studies | 3 | 0.0 |
*Genetic Screening | 2 | 1.0 |
Heterozygote | 4 | 0.0 |
Models, Molecular | 5 | 0.0 |
Molecular Sequence Data | 73 | 0.0 |
Mutation/*genetics | 9 | 0.0 |
Protein Structure, Tertiary | 8 | 0.0 |
Receptor Protein-Tyrosine Kinases/chemistry/*genetics | 5 | 29.0 |
Receptors, Fibroblast Growth Factor/chemistry/*genetics | 6 | 46.0 |
Middle Aged | 18 | 0.0 |
Receptor Protein-Tyrosine Kinases/metabolism | 3 | 1.0 |
Receptors, Fibroblast Growth Factor/*metabolism | 8 | 14.0 |
Tissue Distribution | 6 | 0.0 |
Craniosynostoses/genetics | 4 | 44.0 |
*Gene Expression | 3 | 0.0 |
Osteogenesis/genetics | 3 | 23.0 |
*Phenotype | 2 | 0.0 |
RNA, Messenger/analysis | 7 | 0.0 |
Skull/*embryology | 3 | 37.0 |
Acrocephalosyndactylia/genetics | 12 | 92.0 |
Codon/genetics | 2 | 0.0 |
Craniofacial Dysostosis/genetics | 6 | 85.0 |
Craniosynostoses/*genetics | 19 | 52.0 |
Japan | 4 | 0.0 |
Polymerase Chain Reaction | 27 | 0.0 |
Syndactyly/genetics | 2 | 22.0 |
Embryonic and Fetal Development | 3 | 0.0 |
Mutation | 22 | 0.0 |
Receptor Protein-Tyrosine Kinases/*metabolism | 4 | 1.0 |
Chromosome Mapping | 11 | 0.0 |
*Chromosomes, Human, Pair 10 | 6 | 3.0 |
*Loss of Heterozygosity | 2 | 0.0 |
Microsatellite Repeats | 2 | 0.0 |
Blotting, Northern | 5 | 0.0 |
Receptor Protein-Tyrosine Kinases/genetics/metabolism | 4 | 6.0 |
Receptors, Fibroblast Growth Factor/genetics/metabolism | 2 | 8.0 |
Time Factors | 3 | 0.0 |
Craniosynostoses/*genetics/radiography | 4 | 100.0 |
Gene Expression Regulation, Developmental | 2 | 0.0 |
Chromosomes, Human, Pair 10 | 2 | 1.0 |
*Oligonucleotide Array Sequence Analysis | 2 | 1.0 |
Receptor Protein-Tyrosine Kinases/*biosynthesis/*genetics | 2 | 33.0 |
Receptors, Fibroblast Growth Factor/*biosynthesis/*genetics | 2 | 100.0 |
DNA Primers | 7 | 0.0 |
Blotting, Western | 6 | 0.0 |
Cell Differentiation/physiology | 5 | 1.0 |
Fibroblast Growth Factor 1 | 5 | 17.0 |
Gene Frequency | 2 | 0.0 |
Mice, Inbred BALB C | 4 | 0.0 |
Recombinant Proteins/pharmacology | 3 | 0.0 |
Transfection | 15 | 0.0 |
Fibroblast Growth Factors/*physiology | 2 | 10.0 |
Signal Transduction/*physiology | 5 | 0.0 |
Tumor Cells, Cultured | 18 | 0.0 |
Fibroblast Growth Factors/*metabolism | 7 | 17.0 |
Protein Isoforms/metabolism | 2 | 1.0 |
Comparative Study | 21 | 0.0 |
Cell Division/physiology | 3 | 0.0 |
Transcription Factors/genetics/metabolism | 4 | 0.0 |
Cell Line, Tumor | 4 | 0.0 |
Cell Lineage | 2 | 0.0 |
Gene Deletion | 5 | 0.0 |
Promoter Regions (Genetics) | 4 | 0.0 |
COS Cells | 3 | 0.0 |
Osteoblasts/*cytology | 2 | 11.0 |
Phosphorylation | 5 | 0.0 |
Binding Sites | 4 | 0.0 |
Crystallography, X-Ray | 3 | 0.0 |
Hydrogen Bonding | 3 | 1.0 |
Mutagenesis, Site-Directed | 6 | 0.0 |
Protein Conformation | 4 | 0.0 |
Protein Structure, Secondary | 4 | 0.0 |
Sequence Alignment | 9 | 0.0 |
Sequence Homology, Amino Acid | 13 | 0.0 |
Asian Continental Ancestry Group/*genetics | 2 | 0.0 |
Craniofacial Dysostosis/*genetics | 12 | 92.0 |
Acanthosis Nigricans/genetics | 2 | 100.0 |
Gene Expression | 12 | 0.0 |
Hand Deformities, Congenital/*genetics | 3 | 18.0 |
*Gene Expression Regulation, Developmental | 2 | 0.0 |
Helix-Loop-Helix Motifs | 3 | 1.0 |
Rats | 14 | 0.0 |
Conserved Sequence | 4 | 0.0 |
Stomach Neoplasms/*genetics | 3 | 2.0 |
Models, Genetic | 8 | 0.0 |
Plasmids/metabolism | 4 | 0.0 |
Point Mutation | 17 | 0.0 |
Fibroblast Growth Factor 2/metabolism | 6 | 6.0 |
Growth Substances/*metabolism | 3 | 2.0 |
Receptors, Growth Factor/*metabolism | 2 | 1.0 |
Transforming Growth Factor beta/metabolism | 2 | 1.0 |
Homeodomain Proteins/genetics | 2 | 0.0 |
Morphogenesis | 2 | 0.0 |
Cell Differentiation/genetics | 2 | 0.0 |
Receptors, Fibroblast Growth Factor/*genetics/physiology | 2 | 50.0 |
Cysteine/genetics | 2 | 1.0 |
Genetic Screening | 2 | 0.0 |
Nuclear Proteins/genetics | 3 | 1.0 |
*Transcription Factors | 3 | 0.0 |
Alternative Splicing | 8 | 0.0 |
DNA, Complementary/analysis/genetics | 2 | 2.0 |
Gene Expression Regulation | 5 | 0.0 |
Receptors, Fibroblast Growth Factor/*biosynthesis/genetics | 3 | 27.0 |
Mutation, Missense/genetics | 3 | 1.0 |
Prenatal Diagnosis/*methods | 2 | 1.0 |
3T3 Cells | 6 | 0.0 |
Ligands | 11 | 0.0 |
Craniofacial Abnormalities/genetics/*pathology | 2 | 40.0 |
Receptors, Fibroblast Growth Factor/*genetics/metabolism | 9 | 40.0 |
Surface Plasmon Resonance | 2 | 1.0 |
Exons | 25 | 0.0 |
Foot Deformities/genetics | 2 | 33.0 |
Hand Deformities/genetics | 2 | 50.0 |
Polydactyly/genetics | 2 | 9.0 |
Craniosynostoses/*genetics/pathology | 4 | 66.0 |
DNA/genetics | 2 | 0.0 |
Haplotypes | 2 | 0.0 |
DNA, Neoplasm/genetics | 2 | 0.0 |
Polymerase Chain Reaction/methods | 4 | 0.0 |
Gene Frequency/genetics | 2 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 9 | 0.0 |
Variation (Genetics) | 7 | 0.0 |
Fibroblast Growth Factor 2/*biosynthesis | 2 | 9.0 |
Neovascularization, Pathologic/pathology | 2 | 3.0 |
DNA Primers/chemistry | 3 | 0.0 |
Point Mutation/*genetics | 5 | 1.0 |
Sequence Analysis, DNA | 3 | 0.0 |
Culture Media, Serum-Free | 2 | 0.0 |
Dose-Response Relationship, Drug | 3 | 0.0 |
Fibroblast Growth Factor 2/chemistry/metabolism | 2 | 100.0 |
Protein Binding | 7 | 0.0 |
Protein Isoforms | 4 | 0.0 |
Acrocephalosyndactylia/*diagnosis | 2 | 100.0 |
Cell Differentiation/*physiology | 2 | 0.0 |
Receptors, Fibroblast Growth Factor/biosynthesis/*genetics | 3 | 27.0 |
DNA Primers/genetics | 3 | 0.0 |
Synostosis/*genetics/radiography | 2 | 100.0 |
Cephalometry | 3 | 11.0 |
Skull/*abnormalities | 3 | 15.0 |
Follow-Up Studies | 2 | 0.0 |
Fibroblast Growth Factor 2/*pharmacology | 3 | 2.0 |
Alkaline Phosphatase/metabolism | 2 | 1.0 |
Cell Differentiation/drug effects | 3 | 0.0 |
Cell Division/drug effects | 7 | 0.0 |
Mice, Transgenic | 4 | 0.0 |
Receptor Protein-Tyrosine Kinases/*genetics/metabolism | 6 | 9.0 |
*Signal Transduction | 2 | 0.0 |
Age Factors | 2 | 0.0 |
*Paternal Age | 2 | 50.0 |
Protein-Tyrosine Kinase/*genetics | 2 | 0.0 |
*Repressor Proteins | 2 | 0.0 |
RNA Splicing/genetics | 3 | 2.0 |
Fetus | 2 | 0.0 |
Spine/*abnormalities | 2 | 22.0 |
Mice, Inbred C57BL | 6 | 0.0 |
Genetic Markers/genetics | 2 | 0.0 |
Pregnancy Trimester, Second | 2 | 0.0 |
Sensitivity and Specificity | 2 | 0.0 |
Mice, Knockout | 3 | 0.0 |
Receptor Protein-Tyrosine Kinases/genetics/*metabolism | 2 | 1.0 |
Gene Amplification | 2 | 0.0 |
Sequence Deletion | 5 | 0.0 |
Chromosome Aberrations | 2 | 0.0 |
Consensus Sequence | 2 | 0.0 |
DNA, Complementary/genetics | 2 | 0.0 |
Organ Specificity | 3 | 0.0 |
Craniosynostoses/classification/*diagnosis/genetics | 2 | 100.0 |
*DNA Mutational Analysis | 4 | 2.0 |
Introns | 5 | 0.0 |
*Polymerase Chain Reaction | 2 | 0.0 |
Craniofacial Dysostosis/*genetics/radiography | 2 | 100.0 |
Head/radiography | 2 | 100.0 |
*Penetrance | 2 | 6.0 |
Receptor Protein-Tyrosine Kinases/genetics/*physiology | 2 | 7.0 |
Receptors, Fibroblast Growth Factor/genetics/*physiology | 3 | 33.0 |
Kinetics | 5 | 0.0 |
Magnetic Resonance Imaging | 3 | 0.0 |
Blotting, Southern | 5 | 0.0 |
Brain Neoplasms/*pathology | 2 | 2.0 |
Fibroblast Growth Factors/*biosynthesis/genetics | 2 | 20.0 |
Genetic Vectors | 2 | 0.0 |
Green Fluorescent Proteins | 2 | 0.0 |
Integrases/genetics/*metabolism | 2 | 28.0 |
Viral Proteins/genetics/*metabolism | 2 | 3.0 |
Mice, Mutant Strains | 3 | 0.0 |
Diagnosis, Differential | 3 | 0.0 |
Cysteine | 2 | 1.0 |
Receptor Protein-Tyrosine Kinases/analysis/genetics | 2 | 28.0 |
*Chromosome Mapping | 2 | 0.0 |
Cloning, Molecular | 8 | 0.0 |
Evolution, Molecular | 2 | 0.0 |
Phylogeny | 2 | 0.0 |
Genes, Dominant | 5 | 0.0 |
Precipitin Tests | 3 | 0.0 |
Protein-Tyrosine Kinase/metabolism | 2 | 0.0 |
Ubiquitin/metabolism | 2 | 0.0 |
Craniofacial Abnormalities/genetics | 2 | 8.0 |
Acrocephalosyndactylia/*genetics/radiography | 3 | 100.0 |
Receptors, Growth Factor/genetics | 2 | 4.0 |
Cysteine/*genetics | 2 | 7.0 |
*Fibroblast Growth Factors | 8 | 9.0 |
Growth Substances/genetics/*metabolism | 2 | 4.0 |
*Receptors, Fibroblast Growth Factor | 4 | 30.0 |
Receptors, Growth Factor/genetics/*metabolism | 2 | 6.0 |
Recombinant Proteins/genetics/metabolism | 2 | 0.0 |
Genetic Heterogeneity | 3 | 1.0 |
Antibodies, Monoclonal | 2 | 0.0 |
Species Specificity | 2 | 0.0 |
*Transcription, Genetic | 3 | 0.0 |
Craniofacial Dysostosis/genetics/metabolism | 2 | 100.0 |
Craniosynostoses/*genetics/metabolism | 2 | 100.0 |
Abnormalities, Multiple/genetics/pathology | 2 | 12.0 |
Foot Deformities, Congenital/genetics | 2 | 18.0 |
Growth Substances/*genetics | 2 | 1.0 |
Limb Deformities, Congenital/*genetics | 2 | 10.0 |
Models, Biological | 3 | 0.0 |
Apoptosis | 3 | 0.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism | 2 | 0.0 |
Epidermal Growth Factor/metabolism | 2 | 0.0 |
Receptor, Epidermal Growth Factor/metabolism | 2 | 0.0 |
Gene Expression/physiology | 2 | 0.0 |
*Genes, Dominant | 2 | 0.0 |
DNA | 3 | 0.0 |
Craniofacial Dysostosis/complications/*genetics | 2 | 100.0 |
*Sequence Deletion | 2 | 0.0 |
Sequence Homology, Nucleic Acid | 3 | 0.0 |
Restriction Mapping | 2 | 0.0 |
DNA, Complementary | 2 | 0.0 |
Linkage (Genetics) | 2 | 0.0 |
Cell Division | 5 | 0.0 |
*Gene Expression Regulation, Neoplastic | 2 | 0.0 |
Transcription, Genetic | 2 | 0.0 |
DNA/biosynthesis | 2 | 0.0 |
Foot Deformities, Congenital/*genetics | 2 | 15.0 |
RNA, Messenger | 2 | 0.0 |
Binding, Competitive | 2 | 0.0 |
Mice, Inbred Strains | 2 | 0.0 |
Substrate Specificity | 2 | 0.0 |
*Gene Amplification | 2 | 0.0 |
Prostate/*enzymology | 2 | 1.0 |
DNA/genetics/isolation & purification | 2 | 0.0 |
Neoplasm Staging | 2 | 0.0 |
Chromosomes, Human, Pair 10/*genetics | 2 | 1.0 |
Gene Amplification/genetics | 2 | 3.0 |
Expressed Sequence Tags | 2 | 0.0 |
Membrane Proteins/*genetics | 2 | 0.0 |
Fibroblast Growth Factor 1/metabolism | 2 | 28.0 |
Xenopus | 2 | 0.0 |
