MeSH term
Frequency | Condition_Probility | Animals | 68 | 0.0 |
Comparative Study | 27 | 0.0 |
Cytochrome P-450 CYP1A1/metabolism | 2 | 3.0 |
Cytochrome P-450 CYP1A2/metabolism | 2 | 2.0 |
Cytochrome P-450 CYP2B1/metabolism | 2 | 18.0 |
Cytochrome P-450 CYP2E1/metabolism | 3 | 6.0 |
Humans | 70 | 0.0 |
In Vitro | 4 | 0.0 |
Mice | 26 | 0.0 |
Microsomes, Liver/metabolism | 3 | 1.0 |
Rats | 37 | 0.0 |
Rats, Sprague-Dawley | 17 | 0.0 |
Species Specificity | 12 | 0.0 |
*Aryl Hydrocarbon Hydroxylases | 22 | 2.0 |
Cytochrome P-450 Enzyme System/*antagonists & inhibitors | 4 | 3.0 |
Enzyme Activation | 2 | 0.0 |
Enzyme Inhibitors/*pharmacology | 2 | 0.0 |
Female | 27 | 0.0 |
Kinetics | 7 | 0.0 |
Models, Chemical | 2 | 0.0 |
Oxygen/metabolism | 2 | 0.0 |
Rabbits | 7 | 0.0 |
Research Support, Non-U.S. Gov't | 52 | 0.0 |
Biotransformation | 10 | 1.0 |
Chromatography, High Pressure Liquid | 5 | 0.0 |
Cytochrome P-450 Enzyme System/*metabolism | 17 | 3.0 |
Dogs | 6 | 0.0 |
Isoenzymes/metabolism | 11 | 2.0 |
Male | 49 | 0.0 |
Microsomes, Liver/*enzymology | 11 | 5.0 |
Rats, Inbred F344 | 4 | 1.0 |
Recombinant Proteins/metabolism | 3 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 24 | 0.0 |
Stereoisomerism | 2 | 0.0 |
Base Sequence | 10 | 0.0 |
Binding Sites | 5 | 0.0 |
Models, Biological | 2 | 0.0 |
Molecular Sequence Data | 10 | 0.0 |
Phenobarbital/*pharmacology | 4 | 23.0 |
Protein Binding | 3 | 0.0 |
Sequence Homology, Nucleic Acid | 3 | 0.0 |
Signal Transduction | 3 | 0.0 |
Transcription, Genetic | 4 | 0.0 |
Immunoblotting | 6 | 0.0 |
Immunohistochemistry | 4 | 0.0 |
Phenobarbital/pharmacology | 6 | 9.0 |
Receptors, Cytoplasmic and Nuclear/*metabolism | 4 | 2.0 |
Transcription Factors/*metabolism | 2 | 0.0 |
Isoenzymes | 3 | 1.0 |
Cytochrome P-450 Enzyme System/drug effects/*metabolism | 2 | 9.0 |
Dose-Response Relationship, Drug | 9 | 0.0 |
Organ Size/drug effects | 2 | 2.0 |
Disease Models, Animal | 2 | 0.0 |
Enzyme-Linked Immunosorbent Assay | 3 | 0.0 |
Liver/*metabolism | 2 | 0.0 |
Mice, Transgenic | 3 | 0.0 |
Microsomes, Liver/enzymology | 2 | 0.0 |
Cytochrome P-450 Enzyme System/*biosynthesis/genetics | 2 | 2.0 |
Enzyme Induction/drug effects | 14 | 3.0 |
Liver/drug effects/*enzymology | 2 | 5.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Cattle | 3 | 0.0 |
Hydroxylation | 8 | 2.0 |
Isoenzymes/*metabolism | 3 | 1.0 |
Rats, Wistar | 6 | 0.0 |
Enzyme Inhibitors/pharmacology | 3 | 0.0 |
Mixed Function Oxygenases/biosynthesis/genetics | 2 | 20.0 |
Rifampin/pharmacology | 2 | 3.0 |
*Steroid 16-alpha-Hydroxylase | 2 | 1.0 |
Steroid Hydroxylases/biosynthesis | 2 | 22.0 |
Time Factors | 3 | 0.0 |
Cells, Cultured | 16 | 0.0 |
Amino Acid Sequence | 7 | 0.0 |
Cell Line | 5 | 0.0 |
Hepatocytes/metabolism | 2 | 2.0 |
Ligands | 2 | 0.0 |
Liver/metabolism | 2 | 0.0 |
Mice, Inbred BALB C | 2 | 0.0 |
Mixed Function Oxygenases/metabolism | 3 | 2.0 |
Protein Structure, Tertiary | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 3 | 0.0 |
Transfection | 5 | 0.0 |
Enzyme Induction | 11 | 1.0 |
Cytochrome P-450 CYP1A1 | 3 | 7.0 |
Steroid Hydroxylases/metabolism | 2 | 3.0 |
Cytochrome P-450 Enzyme System/*biosynthesis | 3 | 3.0 |
Hepatocytes/cytology/drug effects/*enzymology | 2 | 66.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 6 | 0.0 |
Microsomes, Liver/*drug effects/enzymology | 3 | 8.0 |
Tumor Cells, Cultured | 4 | 0.0 |
Antibodies | 2 | 0.0 |
Sequence Homology, Amino Acid | 2 | 0.0 |
Liver/*enzymology | 4 | 0.0 |
Seals, Earless/*metabolism | 2 | 66.0 |
Seawater | 2 | 20.0 |
Xenobiotics/*metabolism | 2 | 3.0 |
Adult | 4 | 0.0 |
Aged | 4 | 0.0 |
Middle Aged | 8 | 0.0 |
Cytochrome P-450 Enzyme System/*genetics/metabolism | 3 | 2.0 |
Gene Expression Regulation, Enzymologic/drug effects | 3 | 1.0 |
Swine | 3 | 0.0 |
Rifampin/*pharmacology | 2 | 4.0 |
Testosterone/metabolism | 4 | 3.0 |
Liver/drug effects/enzymology | 2 | 3.0 |
Cytochrome P-450 Enzyme System/genetics/*metabolism | 4 | 2.0 |
Dexamethasone/pharmacology | 4 | 0.0 |
Liver/*drug effects/enzymology | 4 | 9.0 |
Mice, Inbred Strains | 2 | 0.0 |
Microsomes, Liver/drug effects/enzymology | 2 | 2.0 |
Cytochrome P-450 CYP1A1/biosynthesis | 3 | 10.0 |
Cytochrome P-450 CYP2B1/biosynthesis | 2 | 40.0 |
Cytochrome P-450 Enzyme System/biosynthesis | 4 | 21.0 |
Mixed Function Oxygenases/biosynthesis | 3 | 21.0 |
Cytochrome P-450 Enzyme System/metabolism | 3 | 1.0 |
Hamsters | 5 | 0.0 |
Mesocricetus | 2 | 1.0 |
Catalysis | 3 | 0.0 |
Cloning, Molecular | 2 | 0.0 |
DNA Primers | 3 | 0.0 |
Polymerase Chain Reaction | 5 | 0.0 |
Alleles | 3 | 0.0 |
Blotting, Southern | 4 | 0.0 |
Child | 2 | 0.0 |
Mutation | 2 | 0.0 |
Restriction Mapping | 3 | 0.0 |
Gene Expression Regulation, Enzymologic/*drug effects | 2 | 1.0 |
Cluster Analysis | 2 | 1.0 |
DNA, Complementary/genetics | 2 | 0.0 |
Sequence Analysis, DNA | 2 | 0.0 |
Isoenzymes/biosynthesis | 3 | 6.0 |
Blotting, Western | 8 | 0.0 |
Cytochrome P-450 Enzyme System/biosynthesis/*genetics | 4 | 10.0 |
Nucleic Acid Hybridization | 2 | 0.0 |
Structure-Activity Relationship | 3 | 0.0 |
beta-Naphthoflavone | 2 | 11.0 |
*DNA Damage | 2 | 0.0 |
Gene Expression Regulation, Enzymologic | 5 | 0.0 |
Lung/*enzymology | 3 | 4.0 |
Oxidoreductases, N-Demethylating/genetics | 2 | 18.0 |
RNA, Messenger/analysis | 3 | 0.0 |
Troleandomycin/pharmacology | 2 | 3.0 |
Isoenzymes/genetics/*metabolism | 2 | 2.0 |
RNA, Messenger/genetics/metabolism | 2 | 0.0 |
English Abstract | 2 | 0.0 |
Rats, Inbred Strains | 2 | 0.0 |
Antibodies, Monoclonal/pharmacology | 2 | 0.0 |
Cytochrome P-450 CYP2E1 | 3 | 2.0 |
Microsomes/enzymology | 2 | 1.0 |
Reference Values | 2 | 0.0 |
Benzoflavones/pharmacology | 2 | 4.0 |
Oxazines/chemistry/*metabolism | 2 | 100.0 |
Substrate Specificity | 5 | 0.0 |
Chromosome Mapping | 8 | 0.0 |
*Chromosomes, Human, Pair 19 | 8 | 2.0 |
Cytochrome P-450 Enzyme System/*genetics | 6 | 1.0 |
Macaca fascicularis | 2 | 0.0 |
Microsomes, Liver/*metabolism | 3 | 1.0 |
Oxidation-Reduction | 3 | 0.0 |
Cytochrome P-450 CYP2B1 | 2 | 50.0 |
Oxidoreductases/antagonists & inhibitors/metabolism | 2 | 50.0 |
*Multigene Family | 3 | 0.0 |
Phenotype | 2 | 0.0 |
Linkage (Genetics) | 3 | 0.0 |
Recombination, Genetic | 2 | 0.0 |
Lod Score | 2 | 0.0 |
*Linkage (Genetics) | 2 | 0.0 |
Xenobiotics/pharmacology | 2 | 8.0 |
RNA, Messenger/biosynthesis | 2 | 0.0 |
Receptors, Steroid/metabolism | 2 | 4.0 |
Transcription Factors/metabolism | 2 | 0.0 |
