MeSH term
Frequency | Condition_Probility | Humans | 100 | 0.0 |
Adult | 18 | 0.0 |
Aldosterone/blood | 7 | 3.0 |
Aldosterone Synthase/genetics | 6 | 33.0 |
Blood Pressure | 2 | 0.0 |
Crossing Over, Genetic | 2 | 2.0 |
Female | 35 | 0.0 |
Glucocorticoids/*therapeutic use | 5 | 13.0 |
Male | 41 | 0.0 |
Middle Aged | 13 | 0.0 |
Pedigree | 13 | 0.0 |
Phenotype | 4 | 0.0 |
Pregnancy | 4 | 0.0 |
Steroid 11-beta-Hydroxylase/genetics | 11 | 64.0 |
Aldosterone Synthase/*genetics | 19 | 27.0 |
Animals | 41 | 0.0 |
Cattle | 10 | 0.0 |
Mice | 4 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 23 | 0.0 |
Steroid 11-beta-Hydroxylase/*genetics | 28 | 82.0 |
Transfection | 16 | 0.0 |
Tumor Cells, Cultured | 4 | 0.0 |
Autoradiography | 2 | 0.0 |
Cytochrome P-450 Enzyme System/*metabolism | 2 | 0.0 |
In Vitro | 5 | 0.0 |
Research Support, Non-U.S. Gov't | 64 | 0.0 |
Chromatography, High Pressure Liquid | 2 | 0.0 |
Dose-Response Relationship, Drug | 2 | 0.0 |
Enzyme Inhibitors/*pharmacology | 2 | 0.0 |
Forskolin/pharmacology | 2 | 0.0 |
Hydrocortisone/*biosynthesis | 3 | 50.0 |
Ketoconazole/pharmacology | 3 | 3.0 |
Metyrapone/pharmacology | 2 | 15.0 |
Amino Acid Sequence | 14 | 0.0 |
Cytochrome P-450 Enzyme System/genetics | 3 | 2.0 |
Models, Molecular | 3 | 0.0 |
Molecular Sequence Data | 26 | 0.0 |
Mutagenesis, Site-Directed | 6 | 0.0 |
Sequence Homology, Amino Acid | 4 | 0.0 |
Species Specificity | 5 | 0.0 |
Substrate Specificity | 4 | 0.0 |
Binding Sites | 2 | 0.0 |
Comparative Study | 10 | 0.0 |
Mitochondria/enzymology | 3 | 2.0 |
Protein Structure, Secondary | 2 | 0.0 |
Sequence Alignment | 3 | 0.0 |
Steroid 11-beta-Hydroxylase/*chemistry | 2 | 100.0 |
Structure-Activity Relationship | 3 | 0.0 |
CHO Cells | 2 | 0.0 |
Hamsters | 7 | 0.0 |
Blotting, Southern | 8 | 0.0 |
Kinetics | 6 | 0.0 |
Oligonucleotide Probes | 3 | 0.0 |
RNA, Messenger/biosynthesis | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 8 | 0.0 |
Steroid 11-beta-Hydroxylase/biosynthesis | 2 | 100.0 |
Steroids/*biosynthesis | 3 | 5.0 |
Aged | 8 | 0.0 |
Chimera | 2 | 1.0 |
Promoter Regions (Genetics) | 5 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 3 | 0.0 |
In Situ Hybridization | 5 | 0.0 |
Adrenal Hyperplasia, Congenital/*enzymology/*genetics | 2 | 100.0 |
Alleles | 4 | 0.0 |
COS Cells | 4 | 0.0 |
Child, Preschool | 6 | 0.0 |
Cloning, Molecular | 8 | 0.0 |
Crossing Over, Genetic/*genetics | 2 | 22.0 |
Plasmids/genetics | 2 | 0.0 |
Aldosterone Synthase/*metabolism | 3 | 100.0 |
Steroid 11-beta-Hydroxylase/*metabolism | 3 | 75.0 |
Adrenal Cortex/metabolism | 2 | 11.0 |
Cells, Cultured | 6 | 0.0 |
Cholesterol/biosynthesis | 2 | 13.0 |
Imidazoles/*pharmacology | 2 | 2.0 |
Kidney/metabolism | 2 | 0.0 |
Rats | 14 | 0.0 |
Rats, Wistar | 2 | 0.0 |
Steroid 11-beta-Hydroxylase/metabolism | 2 | 66.0 |
Adrenal Hyperplasia, Congenital/*genetics | 2 | 8.0 |
Base Sequence | 27 | 0.0 |
Restriction Mapping | 4 | 0.0 |
Sequence Analysis, DNA | 2 | 0.0 |
Steroid 11-beta-Hydroxylase/*genetics/metabolism | 4 | 80.0 |
*Crossing Over, Genetic | 2 | 6.0 |
DNA, Complementary/genetics | 3 | 0.0 |
Exons | 10 | 0.0 |
Gene Expression | 3 | 0.0 |
Homozygote | 2 | 0.0 |
Polymerase Chain Reaction | 13 | 0.0 |
Renin/blood | 5 | 1.0 |
Genotype | 5 | 0.0 |
*Polymorphism, Genetic | 4 | 0.0 |
Steroid 11-beta-Hydroxylase/genetics/metabolism | 4 | 66.0 |
Case-Control Studies | 2 | 0.0 |
Hyperaldosteronism/*genetics | 2 | 40.0 |
Polymorphism, Single-Stranded Conformational | 2 | 0.0 |
Mutation/*genetics | 2 | 0.0 |
Angiotensin II/pharmacology | 2 | 2.0 |
Cell Line | 11 | 0.0 |
Stereoisomerism | 2 | 0.0 |
Transcription, Genetic/physiology | 2 | 1.0 |
Adrenal Glands/metabolism | 3 | 6.0 |
Cortodoxone/metabolism | 3 | 75.0 |
DNA/genetics | 2 | 0.0 |
Hydrocortisone/biosynthesis | 7 | 43.0 |
RNA, Messenger/metabolism | 2 | 0.0 |
Aldosterone/biosynthesis | 7 | 50.0 |
Hydrocortisone/metabolism | 4 | 12.0 |
Hypertension/*genetics | 3 | 2.0 |
*Mutation | 8 | 0.0 |
Chromosome Banding | 2 | 0.0 |
Chromosome Mapping | 3 | 0.0 |
Family Health | 2 | 0.0 |
Haplotypes | 3 | 0.0 |
Renin/*blood | 2 | 2.0 |
Hypertension/etiology | 2 | 4.0 |
Hypokalemia/etiology | 2 | 50.0 |
Blotting, Western | 2 | 0.0 |
Corticotropin/metabolism | 2 | 5.0 |
Enzyme Activation | 2 | 0.0 |
Gene Expression Regulation | 3 | 0.0 |
Mutation | 11 | 0.0 |
Steroids/metabolism | 3 | 9.0 |
Transcription, Genetic | 2 | 0.0 |
11-beta-Hydroxysteroid Dehydrogenases | 2 | 8.0 |
DNA Primers | 7 | 0.0 |
Adolescent | 4 | 0.0 |
Adrenalectomy | 2 | 4.0 |
Diagnosis, Differential | 2 | 0.0 |
Steroid 17-alpha-Hydroxylase/genetics | 3 | 10.0 |
Immunohistochemistry | 2 | 0.0 |
Child | 5 | 0.0 |
*Adrenal Hyperplasia, Congenital | 3 | 13.0 |
Aldosterone/*biosynthesis | 9 | 56.0 |
Hyperaldosteronism/genetics | 2 | 66.0 |
Desoxycorticosterone/metabolism | 3 | 75.0 |
Hydroxylation | 5 | 1.0 |
Cercopithecus aethiops | 2 | 0.0 |
Steroid 11-beta-Hydroxylase/*physiology | 2 | 100.0 |
Aldosterone/*metabolism | 3 | 30.0 |
Time Factors | 3 | 0.0 |
Catalysis | 2 | 0.0 |
Gene Conversion | 2 | 3.0 |
*Gene Expression Regulation, Enzymologic | 2 | 0.0 |
Gene Frequency | 2 | 0.0 |
Introns | 3 | 0.0 |
Polymorphism, Genetic | 3 | 0.0 |
Potassium/blood | 2 | 2.0 |
Aldosterone Synthase/*antagonists & inhibitors/genetics/metabolism | 2 | 100.0 |
Recombinant Proteins/antagonists & inhibitors/genetics/metabolism | 2 | 6.0 |
*Point Mutation | 4 | 0.0 |
Amino Acid Substitution | 2 | 0.0 |
Recombination, Genetic | 3 | 0.0 |
Rats, Sprague-Dawley | 3 | 0.0 |
Infant | 2 | 0.0 |
Infant, Newborn | 2 | 0.0 |
Polymerase Chain Reaction/methods | 4 | 0.0 |
DNA, Complementary | 3 | 0.0 |
Mixed Function Oxygenases/*deficiency | 4 | 25.0 |
Reference Values | 4 | 0.0 |
Aldosterone Synthase | 15 | 75.0 |
Corticotropin/pharmacology | 2 | 3.0 |
Cytochrome P-450 Enzyme System/*genetics | 7 | 1.0 |
Gene Expression Regulation, Enzymologic | 2 | 0.0 |
Dexamethasone/*therapeutic use | 2 | 11.0 |
Adrenal Glands/*enzymology | 2 | 15.0 |
Cricetulus | 3 | 0.0 |
Mitochondria/*enzymology | 2 | 1.0 |
Adrenal Cortex/*enzymology | 2 | 33.0 |
Chimeric Proteins/metabolism | 2 | 1.0 |
Polymorphism, Restriction Fragment Length | 2 | 0.0 |
Oligodeoxyribonucleotides/chemistry | 2 | 0.0 |
Prenatal Diagnosis | 2 | 1.0 |
Cytochrome P-450 Enzyme System/*genetics/metabolism | 2 | 1.0 |
DNA | 2 | 0.0 |
Glucocorticoids/*biosynthesis | 2 | 66.0 |
Mineralocorticoids/*biosynthesis | 2 | 100.0 |
Sequence Homology, Nucleic Acid | 3 | 0.0 |
Steroid Hydroxylases/*genetics/metabolism | 2 | 9.0 |
Iran | 2 | 5.0 |
Steroid Hydroxylases/*genetics | 5 | 5.0 |
*Genes, Structural | 2 | 0.0 |
*Multigene Family | 2 | 0.0 |
Oligonucleotide Probes/genetics | 2 | 1.0 |
Genes, Structural | 3 | 0.0 |
Immunoblotting | 2 | 0.0 |
Cholesterol Side-Chain Cleavage Enzyme/genetics | 2 | 9.0 |
