MeSH term
Frequency | Condition_Probility | Female | 25 | 0.0 |
Humans | 668 | 0.0 |
Pregnancy | 2 | 0.0 |
Adolescent | 2 | 0.0 |
Male | 35 | 0.0 |
Tomography, X-Ray Computed | 3 | 0.0 |
Aged | 12 | 0.0 |
Aged, 80 and over | 8 | 0.0 |
Actins/chemistry/*metabolism | 3 | 23.0 |
Animals | 413 | 0.0 |
Cytoskeletal Proteins/metabolism | 17 | 6.0 |
Dogs | 18 | 1.0 |
Enzyme Activation/drug effects | 19 | 2.0 |
In Vitro | 17 | 0.0 |
Mutagenesis, Site-Directed | 29 | 0.0 |
Nerve Tissue Proteins/metabolism | 5 | 2.0 |
Phosphorylation | 102 | 1.0 |
Recombinant Proteins/genetics/metabolism | 8 | 1.0 |
Research Support, Non-U.S. Gov't | 515 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 302 | 0.0 |
cdc42 GTP-Binding Protein/genetics/*metabolism | 25 | 96.0 |
Bacterial Toxins/pharmacology | 12 | 29.0 |
Cells, Cultured | 91 | 0.0 |
Enzyme Activation | 133 | 3.0 |
Epidermal Growth Factor/pharmacology | 7 | 0.0 |
Microscopy, Fluorescence | 41 | 2.0 |
Mitogen-Activated Protein Kinase 1/metabolism | 4 | 1.0 |
Mitogen-Activated Protein Kinase 3 | 6 | 0.0 |
Mitogen-Activated Protein Kinases/*metabolism | 12 | 2.0 |
Osmolar Concentration | 2 | 0.0 |
p38 Mitogen-Activated Protein Kinases | 22 | 3.0 |
rho GTP-Binding Proteins/antagonists & inhibitors/metabolism | 3 | 50.0 |
Cell Adhesion | 24 | 1.0 |
Cell Movement/drug effects/physiology | 4 | 6.0 |
Fibronectins/metabolism | 10 | 5.0 |
Protein-Serine-Threonine Kinases/metabolism | 33 | 3.0 |
rac1 GTP-Binding Protein/*metabolism/pharmacology | 2 | 50.0 |
*Bacterial Proteins | 16 | 8.0 |
Base Sequence | 63 | 0.0 |
Cell Membrane/enzymology | 2 | 0.0 |
Cysteine Endopeptidases/metabolism | 3 | 1.0 |
Hela Cells | 76 | 1.0 |
Plasmids/genetics | 3 | 0.0 |
Proteasome Endopeptidase Complex | 2 | 0.0 |
Recombinant Fusion Proteins/chemistry/genetics/metabolism | 5 | 2.0 |
Sequence Deletion | 8 | 0.0 |
Transfection | 140 | 1.0 |
Ubiquitin/metabolism | 5 | 2.0 |
Bacterial Toxins/genetics/*toxicity | 4 | 100.0 |
CHO Cells | 16 | 0.0 |
Cell Line | 161 | 0.0 |
Hamsters | 22 | 0.0 |
Vimentin/metabolism | 2 | 1.0 |
Amino Acid Sequence | 173 | 0.0 |
Bacterial Proteins/*chemistry/metabolism | 2 | 33.0 |
Comparative Study | 32 | 0.0 |
Crystallography, X-Ray | 5 | 0.0 |
Evolution, Molecular | 5 | 0.0 |
Guanosine Diphosphate/metabolism | 17 | 14.0 |
Guanosine Triphosphate/metabolism | 43 | 14.0 |
Models, Molecular | 23 | 0.0 |
Molecular Sequence Data | 186 | 0.0 |
Protein Conformation | 15 | 0.0 |
Proteins/chemistry/metabolism | 4 | 12.0 |
Recombinant Fusion Proteins/chemistry/metabolism | 4 | 2.0 |
Sequence Alignment | 29 | 0.0 |
Sequence Homology, Amino Acid | 89 | 1.0 |
Signal Transduction | 120 | 2.0 |
Structure-Activity Relationship | 13 | 0.0 |
cdc42 GTP-Binding Protein/*chemistry/metabolism | 3 | 100.0 |
rac1 GTP-Binding Protein/chemistry/metabolism | 3 | 100.0 |
Actins/metabolism | 68 | 13.0 |
Blotting, Northern | 19 | 0.0 |
Cloning, Molecular | 54 | 0.0 |
Cytoskeleton/metabolism | 42 | 17.0 |
DNA, Complementary/metabolism | 22 | 1.0 |
Fibroblasts/metabolism | 7 | 0.0 |
Gene Library | 15 | 1.0 |
Precipitin Tests | 40 | 1.0 |
Protein Binding | 124 | 1.0 |
Protein Structure, Tertiary | 90 | 2.0 |
Rats | 74 | 0.0 |
Recombinant Proteins/chemistry | 3 | 0.0 |
Time Factors | 50 | 0.0 |
Tissue Distribution | 23 | 0.0 |
Two-Hybrid System Techniques | 37 | 3.0 |
cdc42 GTP-Binding Protein/metabolism | 102 | 80.0 |
rho GTP-Binding Proteins/*chemistry/metabolism | 2 | 100.0 |
rhoA GTP-Binding Protein/chemistry/metabolism | 3 | 50.0 |
1-Phosphatidylinositol 3-Kinase/*metabolism | 7 | 2.0 |
Bicyclo Compounds, Heterocyclic/pharmacology | 2 | 9.0 |
*Cell Movement | 6 | 5.0 |
*Cell Polarity | 9 | 26.0 |
*Depsipeptides | 2 | 6.0 |
Enzyme Inhibitors/pharmacology | 33 | 1.0 |
Feedback, Biochemical | 2 | 4.0 |
HL-60 Cells | 8 | 1.0 |
Neutrophils/*cytology | 2 | 10.0 |
Peptides, Cyclic/pharmacology | 2 | 5.0 |
Phosphatidylinositol Phosphates/*metabolism | 2 | 6.0 |
Pseudopodia/drug effects | 2 | 40.0 |
Thiazoles/pharmacology | 2 | 1.0 |
Blood Proteins/*chemistry | 4 | 14.0 |
Dose-Response Relationship, Drug | 20 | 0.0 |
Guanine Nucleotide Exchange Factors/*chemistry/*metabolism | 2 | 28.0 |
Phosphoproteins/*chemistry | 4 | 13.0 |
Plasmids/metabolism | 29 | 2.0 |
RNA/metabolism | 4 | 0.0 |
Recombinant Proteins/metabolism | 40 | 1.0 |
Transcription, Genetic | 15 | 0.0 |
Blotting, Southern | 3 | 0.0 |
Cell Differentiation | 6 | 0.0 |
Chromosome Mapping | 10 | 0.0 |
Introns | 4 | 0.0 |
Mice | 167 | 0.0 |
Protein Isoforms | 5 | 0.0 |
RNA, Messenger/metabolism | 16 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 17 | 0.0 |
Tumor Cells, Cultured | 58 | 0.0 |
src Homology Domains | 23 | 4.0 |
COS Cells | 87 | 3.0 |
Cercopithecus aethiops | 20 | 1.0 |
Glutathione Transferase/metabolism | 21 | 2.0 |
Kinetics | 35 | 0.0 |
Microfilament Proteins/*metabolism | 6 | 9.0 |
Nerve Tissue Proteins/*metabolism | 10 | 3.0 |
Neurites/physiology | 2 | 10.0 |
Recombinant Fusion Proteins/metabolism | 45 | 2.0 |
rac GTP-Binding Proteins/*metabolism | 20 | 35.0 |
Acetylcysteine/*analogs & derivatives/pharmacology | 2 | 4.0 |
*Cell Adhesion | 4 | 2.0 |
Cell Cycle Proteins/metabolism | 25 | 7.0 |
Cysteine Proteinase Inhibitors/pharmacology | 3 | 1.0 |
Down-Regulation | 8 | 0.0 |
Mitogen-Activated Protein Kinases/metabolism | 32 | 3.0 |
Mutation | 67 | 0.0 |
cdc42 GTP-Binding Protein/*metabolism | 77 | 96.0 |
rac1 GTP-Binding Protein/*metabolism | 35 | 38.0 |
Cell Polarity/physiology | 6 | 18.0 |
rho GTP-Binding Proteins/metabolism | 34 | 44.0 |
Adhesins, Bacterial/metabolism | 2 | 40.0 |
Bacterial Adhesion | 4 | 6.0 |
Carrier Proteins/metabolism | 10 | 1.0 |
Cytoskeleton/metabolism/microbiology | 2 | 100.0 |
Epithelial Cells/metabolism/microbiology | 2 | 22.0 |
*Escherichia coli Proteins | 15 | 6.0 |
Models, Biological | 57 | 1.0 |
Pseudopodia/physiology | 2 | 33.0 |
Receptors, Cell Surface/metabolism | 3 | 0.0 |
*Signal Transduction | 40 | 2.0 |
Cadherins/*metabolism | 6 | 8.0 |
Cell Membrane/metabolism/ultrastructure | 2 | 3.0 |
Cell Movement/physiology | 10 | 4.0 |
Coculture Techniques | 3 | 0.0 |
Protein Binding/physiology | 5 | 1.0 |
Rats, Sprague-Dawley | 9 | 0.0 |
Trans-Activators/metabolism | 5 | 0.0 |
Adult | 15 | 0.0 |
Child | 4 | 0.0 |
Follow-Up Studies | 3 | 0.0 |
Middle Aged | 10 | 0.0 |
Risk Factors | 2 | 0.0 |
Calcium/metabolism | 16 | 1.0 |
Chemotactic Factors/*pharmacology | 2 | 5.0 |
*Intercellular Signaling Peptides and Proteins | 2 | 0.0 |
MAP Kinase Kinase 1 | 2 | 1.0 |
Mitogen-Activated Protein Kinase Kinases/metabolism | 4 | 2.0 |
Protein-Serine-Threonine Kinases/*metabolism | 32 | 4.0 |
Protein-Tyrosine Kinase/metabolism | 16 | 1.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 32 | 0.0 |
Signal Transduction/drug effects/physiology | 6 | 2.0 |
Amino Acid Motifs | 15 | 1.0 |
Brain/*enzymology | 2 | 1.0 |
GTP Phosphohydrolases/metabolism | 28 | 20.0 |
In Situ Hybridization | 6 | 0.0 |
Mitogen-Activated Protein Kinase 8 | 5 | 6.0 |
Models, Genetic | 8 | 0.0 |
Phosphoproteins/*metabolism | 7 | 1.0 |
Protein-Tyrosine Kinase/*metabolism | 15 | 1.0 |
rhoA GTP-Binding Protein/*metabolism | 17 | 26.0 |
ADP Ribose Transferases/metabolism | 3 | 21.0 |
Botulinum Toxins/metabolism | 3 | 60.0 |
Cell Size | 19 | 7.0 |
Focal Adhesions/metabolism | 2 | 10.0 |
Immunohistochemistry | 17 | 0.0 |
Microinjections | 11 | 5.0 |
Myosin Light Chains/*metabolism | 3 | 21.0 |
Protein-Serine-Threonine Kinases/antagonists & inhibitors/*metabolism | 2 | 2.0 |
Recombinant Fusion Proteins/genetics/metabolism | 20 | 1.0 |
rhoA GTP-Binding Protein/metabolism | 39 | 41.0 |
Amino Acid Substitution | 9 | 0.0 |
DNA Mutational Analysis | 4 | 0.0 |
Phospholipase D/*metabolism | 3 | 3.0 |
Serine/metabolism | 4 | 1.0 |
rac1 GTP-Binding Protein/genetics/*metabolism | 12 | 37.0 |
rhoA GTP-Binding Protein/genetics/*metabolism | 7 | 35.0 |
Protein Structure, Secondary | 7 | 0.0 |
Substrate Specificity | 25 | 1.0 |
cdc42 GTP-Binding Protein/chemistry/metabolism | 3 | 100.0 |
rho GTP-Binding Proteins/*chemistry/*metabolism | 3 | 75.0 |
Cytoskeletal Proteins/*metabolism | 4 | 2.0 |
Fluorescent Antibody Technique | 19 | 0.0 |
GTPase-Activating Proteins/*metabolism | 7 | 28.0 |
Guanine Nucleotide Exchange Factors/metabolism | 11 | 25.0 |
Oncogene Proteins/metabolism | 9 | 11.0 |
rac1 GTP-Binding Protein/metabolism | 39 | 39.0 |
Amides/pharmacology | 5 | 9.0 |
Bacterial Toxins/*pharmacology | 6 | 19.0 |
Cell Line, Tumor | 23 | 0.0 |
Cytotoxins/*pharmacology | 2 | 22.0 |
Epithelial Cells/drug effects/metabolism | 5 | 5.0 |
Phosphorylation/drug effects | 9 | 1.0 |
Pyridines/pharmacology | 11 | 4.0 |
rac GTP-Binding Proteins/metabolism | 24 | 40.0 |
Alkyl and Aryl Transferases/antagonists & inhibitors | 2 | 28.0 |
Molecular Structure | 6 | 0.0 |
Protein Isoprenylation/drug effects | 3 | 16.0 |
*Mutation | 3 | 0.0 |
Phenotype | 19 | 0.0 |
Polymerase Chain Reaction | 13 | 0.0 |
Up-Regulation | 6 | 0.0 |
*rho GTP-Binding Proteins | 6 | 24.0 |
Actins/physiology | 3 | 8.0 |
Cell Adhesion/*physiology | 8 | 6.0 |
Cell Movement/*physiology | 21 | 10.0 |
Cytoskeleton/physiology | 10 | 12.0 |
cdc42 GTP-Binding Protein/physiology | 14 | 77.0 |
rac1 GTP-Binding Protein/physiology | 6 | 35.0 |
rho GTP-Binding Proteins/physiology | 3 | 23.0 |
rhoA GTP-Binding Protein/physiology | 5 | 35.0 |
Models, Neurological | 3 | 2.0 |
Protein-Serine-Threonine Kinases/physiology | 6 | 6.0 |
rho GTP-Binding Proteins/*physiology | 11 | 32.0 |
Apoptosis/physiology | 2 | 0.0 |
Binding Sites | 57 | 0.0 |
Cell Transformation, Neoplastic | 7 | 1.0 |
Carrier Proteins/genetics/*metabolism | 4 | 0.0 |
Cattle | 12 | 0.0 |
Cytoskeleton/*physiology | 9 | 25.0 |
Saccharomyces cerevisiae/genetics | 6 | 1.0 |
Signal Transduction/*physiology | 31 | 2.0 |
*ras GTPase-Activating Proteins | 24 | 70.0 |
DNA Primers | 14 | 0.0 |
Gastrula/*physiology | 3 | 20.0 |
Movement | 3 | 5.0 |
Proto-Oncogene Proteins/*physiology | 4 | 1.0 |
*Zebrafish Proteins | 2 | 0.0 |
Blotting, Western | 45 | 0.0 |
Cell Movement | 27 | 3.0 |
Gene Deletion | 11 | 0.0 |
Mice, Knockout | 7 | 0.0 |
RNA, Messenger/genetics/metabolism | 7 | 0.0 |
Cell Movement/drug effects/*physiology | 6 | 12.0 |
Neovascularization, Physiologic/drug effects/*physiology | 2 | 4.0 |
Protein-Serine-Threonine Kinases/*physiology | 4 | 3.0 |
Recombinant Fusion Proteins/pharmacology | 3 | 3.0 |
ATP-Binding Cassette Transporters/*metabolism | 2 | 2.0 |
Biological Transport | 11 | 0.0 |
Cell Membrane/metabolism | 19 | 1.0 |
Detergents/pharmacology | 2 | 1.0 |
Electrophoresis, Polyacrylamide Gel | 14 | 0.0 |
Immunoblotting | 14 | 0.0 |
Lipids/*metabolism | 2 | 0.0 |
Macrophages/metabolism | 2 | 0.0 |
Membrane Microdomains/metabolism | 3 | 10.0 |
Monocytes/metabolism | 2 | 0.0 |
Octoxynol/pharmacology | 2 | 3.0 |
Peptides/chemistry | 4 | 1.0 |
Stress Fibers/metabolism | 6 | 26.0 |
Trans-Activators/genetics/metabolism | 2 | 1.0 |
Golgi Apparatus/*metabolism | 2 | 2.0 |
Green Fluorescent Proteins | 19 | 2.0 |
Membrane Glycoproteins/metabolism | 3 | 0.0 |
3T3 Cells | 63 | 3.0 |
Catalytic Domain | 4 | 1.0 |
Cell Membrane/*metabolism | 12 | 4.0 |
*Gene Expression Regulation, Neoplastic | 4 | 0.0 |
JNK Mitogen-Activated Protein Kinases | 54 | 9.0 |
Luciferases/metabolism | 6 | 0.0 |
NF-kappa B/metabolism | 9 | 1.0 |
Promoter Regions (Genetics) | 10 | 0.0 |
Proto-Oncogene Proteins/*metabolism | 17 | 1.0 |
Actins/*metabolism | 49 | 21.0 |
Image Processing, Computer-Assisted | 3 | 0.0 |
Pseudopodia/*physiology/ultrastructure | 2 | 100.0 |
Bacterial Toxins/*metabolism | 3 | 30.0 |
*Apoptosis | 6 | 0.0 |
Bacterial Toxins/*metabolism/pharmacology | 3 | 60.0 |
Cytotoxins/*metabolism/pharmacology | 2 | 66.0 |
*Endocytosis | 2 | 1.0 |
Escherichia coli/*metabolism | 2 | 7.0 |
rho GTP-Binding Proteins/*metabolism | 39 | 46.0 |
Phosphoproteins/metabolism | 17 | 2.0 |
Virulence | 2 | 0.0 |
cdc42 GTP-Binding Protein/genetics/metabolism | 22 | 91.0 |
rho GTP-Binding Proteins/genetics/metabolism | 6 | 66.0 |
Extracellular Matrix/metabolism | 3 | 1.0 |
Fungal Proteins/metabolism | 3 | 1.0 |
Microfilament Proteins/metabolism | 10 | 11.0 |
Morphogenesis | 3 | 1.0 |
Pinocytosis | 2 | 16.0 |
*Saccharomyces cerevisiae Proteins | 17 | 1.0 |
cdc42 GTP-Binding Protein/*physiology | 17 | 100.0 |
rac1 GTP-Binding Protein/*physiology | 3 | 30.0 |
Spectrometry, Fluorescence | 7 | 1.0 |
cdc42 GTP-Binding Protein/chemistry/*metabolism | 4 | 100.0 |
Protein Transport | 9 | 1.0 |
Urinary Plasminogen Activator/*pharmacology | 2 | 25.0 |
Cell Size/drug effects | 7 | 7.0 |
GTP Phosphohydrolases/genetics/*metabolism | 6 | 28.0 |
Guanine Nucleotide Exchange Factors/*metabolism | 9 | 21.0 |
Microscopy, Video | 8 | 10.0 |
Nerve Growth Factor/*pharmacology | 2 | 11.0 |
Neurites/*drug effects/metabolism | 2 | 66.0 |
PC12 Cells | 13 | 3.0 |
rac GTP-Binding Proteins/genetics/*metabolism | 7 | 46.0 |
*Evolution, Molecular | 3 | 0.0 |
Signal Transduction/genetics | 5 | 1.0 |
cdc42 GTP-Binding Protein/*genetics | 2 | 66.0 |
rac GTP-Binding Proteins/*genetics | 2 | 33.0 |
Integrins/*metabolism | 8 | 5.0 |
Blood Platelets/metabolism | 3 | 1.0 |
Cell Surface Extensions/drug effects | 2 | 66.0 |
Chemotaxis/drug effects/physiology | 2 | 9.0 |
*Receptors, G-Protein-Coupled | 5 | 1.0 |
Receptors, Lysophosphatidic Acid | 2 | 4.0 |
Receptors, Lysophospholipid | 3 | 7.0 |
rac GTP-Binding Proteins/drug effects/genetics/*metabolism | 2 | 100.0 |
rhoA GTP-Binding Protein/genetics/metabolism | 6 | 40.0 |
Neoplasm Metastasis | 2 | 0.0 |
Tyrphostins/pharmacology | 2 | 1.0 |
*Adaptor Proteins, Signal Transducing | 15 | 1.0 |
Antineoplastic Agents/*pharmacology | 2 | 0.0 |
Apoptosis/*drug effects/physiology | 2 | 1.0 |
Carrier Proteins/physiology | 3 | 2.0 |
DNA-Binding Protein, Cyclic AMP-Responsive/metabolism | 2 | 1.0 |
K562 Cells | 4 | 0.0 |
Proto-Oncogene Proteins c-jun/metabolism | 4 | 2.0 |
Transcription Factors/metabolism | 9 | 0.0 |
1-Phosphatidylinositol 3-Kinase/antagonists & inhibitors/metabolism | 4 | 4.0 |
rho GTP-Binding Proteins/antagonists & inhibitors/*metabolism | 3 | 33.0 |
Atrial Natriuretic Factor/genetics | 2 | 20.0 |
*Gene Expression Regulation | 9 | 0.0 |
Genes, Reporter | 7 | 0.0 |
Mice, Transgenic | 6 | 0.0 |
Myocardium/*metabolism | 2 | 0.0 |
Trans-Activation (Genetics) | 7 | 0.0 |
Cell Adhesion Molecules/*metabolism | 3 | 1.0 |
Microscopy, Electron | 8 | 0.0 |
Phagocytosis | 5 | 1.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/*metabolism | 22 | 7.0 |
Collagen | 2 | 1.0 |
Receptors, Collagen | 2 | 2.0 |
*Antigens, CD | 3 | 0.0 |
*Cell Cycle Proteins | 12 | 0.0 |
Jurkat Cells | 26 | 1.0 |
Signal Transduction/*immunology | 4 | 1.0 |
T-Lymphocytes/*enzymology/immunology | 2 | 8.0 |
Tyrosine/metabolism | 19 | 1.0 |
Chromosomes, Human, Pair 19 | 2 | 1.0 |
Guanine Nucleotide Exchange Factors/*chemistry/genetics/*metabolism | 2 | 33.0 |
Phylogeny | 15 | 1.0 |
Cell Fractionation | 2 | 0.0 |
Cell Membrane/chemistry/metabolism | 4 | 9.0 |
GTP-Binding Proteins/chemistry/metabolism | 2 | 25.0 |
Carrier Proteins/genetics/metabolism | 3 | 1.0 |
Exocytosis/*physiology | 3 | 9.0 |
Proteins/genetics/metabolism | 9 | 4.0 |
Glioma | 2 | 2.0 |
Growth Cones/physiology | 2 | 66.0 |
Kidney/cytology | 3 | 1.0 |
Neuroblastoma | 2 | 1.0 |
Neurons/metabolism/ultrastructure | 2 | 11.0 |
Pseudopodia/*physiology | 2 | 66.0 |
Receptors, Cell Surface/genetics/*metabolism | 6 | 4.0 |
Algorithms | 3 | 0.0 |
Cell Polarity | 6 | 4.0 |
Fibroblasts | 3 | 0.0 |
Luminescent Proteins | 4 | 6.0 |
Microtubules/metabolism | 2 | 1.0 |
Neutrophil Activation | 3 | 6.0 |
Pseudopodia/metabolism | 4 | 13.0 |
Sensitivity and Specificity | 2 | 0.0 |
Gene Expression Regulation/*physiology | 3 | 0.0 |
Proteins/metabolism | 23 | 2.0 |
*Transcription Factors | 3 | 0.0 |
Tumor Necrosis Factor-alpha/metabolism | 2 | 0.0 |
rho GTP-Binding Proteins/chemistry/genetics/*metabolism | 3 | 100.0 |
Calcium/*metabolism | 3 | 0.0 |
Calmodulin/*metabolism | 5 | 10.0 |
Carrier Proteins/*metabolism | 16 | 2.0 |
Dimerization | 12 | 0.0 |
Cell Division | 17 | 0.0 |
Integrins/metabolism | 3 | 1.0 |
*Intracellular Signaling Peptides and Proteins | 4 | 0.0 |
*Membrane Proteins | 5 | 0.0 |
ADP-Ribosylation Factors/*metabolism | 2 | 5.0 |
Golgi Apparatus/metabolism | 3 | 1.0 |
Ligands | 3 | 0.0 |
Protein-Serine-Threonine Kinases/chemistry/genetics/*metabolism | 2 | 4.0 |
Culture Media, Serum-Free/pharmacology | 2 | 1.0 |
Endocytosis | 4 | 1.0 |
Escherichia coli/metabolism | 8 | 2.0 |
Receptor, Epidermal Growth Factor/*metabolism | 3 | 0.0 |
Caco-2 Cells | 3 | 0.0 |
cdc42 GTP-Binding Protein/genetics/*physiology | 5 | 83.0 |
rac1 GTP-Binding Protein/genetics/*physiology | 3 | 42.0 |
rhoA GTP-Binding Protein/genetics/*physiology | 2 | 33.0 |
Cadherins/metabolism | 5 | 4.0 |
Carrier Proteins/*biosynthesis | 2 | 3.0 |
Gene Expression Regulation, Neoplastic | 6 | 0.0 |
Neoplasm Invasiveness | 7 | 0.0 |
1-Phosphatidylinositol 3-Kinase/physiology | 5 | 4.0 |
Osmotic Pressure | 3 | 4.0 |
rac GTP-Binding Proteins/*physiology | 6 | 60.0 |
GTP-Binding Protein alpha Subunits, Gi-Go/metabolism | 2 | 5.0 |
Microfilament Proteins/genetics/*metabolism | 2 | 8.0 |
Protein Kinase Inhibitors | 2 | 1.0 |
Protein Kinases/*metabolism | 6 | 1.0 |
Mammals | 7 | 1.0 |
Organ Specificity | 5 | 0.0 |
DNA, Complementary/genetics | 5 | 0.0 |
Protein-Serine-Threonine Kinases/chemistry/*genetics/*metabolism | 2 | 13.0 |
Blood Proteins/chemistry | 2 | 9.0 |
Caspases/*metabolism | 3 | 1.0 |
Proteins/*metabolism | 12 | 1.0 |
*Adaptor Proteins, Vesicular Transport | 3 | 1.0 |
Lymphocyte Activation | 6 | 0.0 |
T-Lymphocytes/*immunology | 2 | 0.0 |
Cytoskeleton/physiology/ultrastructure | 5 | 62.0 |
Exocytosis/drug effects/*physiology | 3 | 33.0 |
Tumor Necrosis Factor-alpha/pharmacology | 3 | 0.0 |
*ral GTP-Binding Proteins | 2 | 13.0 |
Microscopy, Electron, Scanning | 5 | 1.0 |
Actins/analysis | 4 | 2.0 |
Antigens, CD/*metabolism | 3 | 0.0 |
*Lymphocyte Activation | 2 | 0.0 |
*MAP Kinase Signaling System | 2 | 1.0 |
Membrane Glycoproteins/*metabolism | 2 | 0.0 |
Proto-Oncogene Proteins/metabolism | 9 | 0.0 |
Cell Nucleus/metabolism | 10 | 0.0 |
Phosphotyrosine/metabolism | 9 | 2.0 |
Cell Communication | 7 | 2.0 |
Gene Expression Regulation | 15 | 0.0 |
Immunoprecipitation | 4 | 1.0 |
Mutagenesis | 9 | 0.0 |
Serine/chemistry | 3 | 2.0 |
Spectrum Analysis, Mass | 3 | 0.0 |
Epithelial Cells/metabolism | 5 | 1.0 |
Proteins/metabolism/*physiology | 3 | 6.0 |
Genes, Dominant | 21 | 2.0 |
Neuroblastoma/metabolism/pathology | 2 | 13.0 |
ras Proteins/*metabolism | 6 | 3.0 |
Oncogene Proteins/*metabolism | 5 | 5.0 |
Platelet-Derived Growth Factor/metabolism | 5 | 7.0 |
src Homology Domains/physiology | 2 | 4.0 |
Bacterial Proteins/*metabolism | 3 | 6.0 |
Luminescent Proteins/metabolism | 8 | 2.0 |
src-Family Kinases/metabolism | 4 | 2.0 |
Cadherins/*physiology | 4 | 19.0 |
Cytoskeletal Proteins/physiology | 3 | 13.0 |
*Trans-Activators | 4 | 0.0 |
Flow Cytometry | 7 | 0.0 |
Gene Expression | 17 | 0.0 |
Reference Values | 4 | 0.0 |
Cell Division/*physiology | 2 | 1.0 |
Endothelium, Vascular/*cytology | 3 | 1.0 |
Vascular Endothelial Growth Factor A | 2 | 0.0 |
Vascular Endothelial Growth Factors | 2 | 0.0 |
Protein-Serine-Threonine Kinases/genetics/*metabolism | 13 | 5.0 |
*Gene Expression | 2 | 0.0 |
Mitogen-Activated Protein Kinases/antagonists & inhibitors | 2 | 3.0 |
cdc42 GTP-Binding Protein/antagonists & inhibitors | 2 | 100.0 |
rac GTP-Binding Proteins/antagonists & inhibitors | 2 | 100.0 |
rho GTP-Binding Proteins/*antagonists & inhibitors | 4 | 66.0 |
Protein Kinase C/antagonists & inhibitors/metabolism | 3 | 3.0 |
Protein-Serine-Threonine Kinases/genetics/metabolism | 8 | 7.0 |
*Cytoskeletal Proteins | 12 | 10.0 |
Nerve Tissue Proteins/genetics/*metabolism | 6 | 4.0 |
Peptide Fragments/metabolism | 3 | 0.0 |
Pseudopodia/*metabolism | 6 | 50.0 |
cdc42 GTP-Binding Protein/metabolism/physiology | 2 | 100.0 |
rac GTP-Binding Proteins/metabolism/physiology | 2 | 66.0 |
rhoA GTP-Binding Protein/metabolism/physiology | 3 | 100.0 |
1-Phosphatidylinositol 3-Kinase/*physiology | 4 | 7.0 |
*Muscle Proteins | 3 | 1.0 |
Antibodies, Blocking/pharmacology | 2 | 2.0 |
Cytoskeleton/drug effects/metabolism | 6 | 20.0 |
Lysosomes/metabolism | 2 | 1.0 |
Protein Binding/drug effects/physiology | 2 | 5.0 |
Protein Structure, Tertiary/physiology | 4 | 2.0 |
cdc42 GTP-Binding Protein/genetics | 5 | 71.0 |
*Drosophila Proteins | 9 | 0.0 |
GTP Phosphohydrolases/*metabolism | 37 | 31.0 |
Receptors, Immunologic/*metabolism | 2 | 1.0 |
Retroviridae/genetics | 3 | 0.0 |
*Cell Transformation, Neoplastic | 9 | 2.0 |
Genes, ras | 5 | 2.0 |
Protein-Serine-Threonine Kinases/genetics/*physiology | 3 | 8.0 |
Threonine/metabolism | 4 | 4.0 |
Cytotoxins/genetics/*toxicity | 3 | 100.0 |
Escherichia coli/genetics/*metabolism | 2 | 18.0 |
Binding, Competitive | 5 | 0.0 |
Cholesterol/metabolism | 3 | 1.0 |
Mice, Inbred C57BL | 7 | 0.0 |
*Promoter Regions (Genetics) | 2 | 0.0 |
Microscopy, Confocal | 12 | 1.0 |
Neutrophils/metabolism | 3 | 2.0 |
*GTP Phosphohydrolase Activators | 5 | 71.0 |
*GTP-Binding Protein Regulators | 4 | 80.0 |
Brain/metabolism | 9 | 1.0 |
Glycoproteins/metabolism | 2 | 1.0 |
Actins/chemistry | 5 | 25.0 |
Myosins/chemistry | 2 | 50.0 |
*Phagocytosis | 2 | 1.0 |
Cytoskeleton/*metabolism | 15 | 12.0 |
Protein-Serine-Threonine Kinases/antagonists & inhibitors/metabolism | 3 | 3.0 |
Luminescent Proteins/*chemistry/genetics | 2 | 100.0 |
Proteins/*physiology | 2 | 1.0 |
Cell Adhesion Molecules/metabolism | 3 | 1.0 |
Proto-Oncogene Protein pp60(c-src)/metabolism | 2 | 5.0 |
Vinculin/metabolism | 4 | 17.0 |
Caenorhabditis elegans | 2 | 2.0 |
*Carrier Proteins | 3 | 0.0 |
Cell Line, Transformed | 9 | 0.0 |
Epithelial Cells/cytology/metabolism | 3 | 5.0 |
*Alternative Splicing | 4 | 0.0 |
Microfilament Proteins/*chemistry | 3 | 42.0 |
Actins/drug effects/metabolism | 2 | 22.0 |
Endothelium, Vascular/drug effects/*enzymology | 2 | 22.0 |
Extracellular Matrix/drug effects/metabolism | 2 | 11.0 |
rho GTP-Binding Proteins/drug effects/*metabolism | 2 | 50.0 |
Fluorides/pharmacology | 2 | 7.0 |
Membrane Proteins/metabolism | 12 | 2.0 |
Subcellular Fractions | 7 | 3.0 |
Antigen-Presenting Cells/*metabolism | 2 | 20.0 |
Cell Compartmentation | 2 | 0.0 |
Lymphocyte Specific Protein Tyrosine Kinase p56(lck)/metabolism | 3 | 5.0 |
Proteins/isolation & purification/*metabolism | 2 | 6.0 |
Receptors, Antigen, T-Cell/metabolism | 2 | 1.0 |
T-Lymphocytes/*metabolism | 3 | 0.0 |
DNA, Complementary | 16 | 0.0 |
Mice, Nude | 4 | 0.0 |
Saccharomyces cerevisiae | 2 | 0.0 |
Cell Movement/drug effects | 6 | 1.0 |
Fluorescent Antibody Technique, Indirect | 2 | 0.0 |
Protein Synthesis Inhibitors/pharmacology | 3 | 0.0 |
Cell Size/genetics | 2 | 12.0 |
Indicators and Reagents/metabolism | 2 | 5.0 |
cdc42 GTP-Binding Protein/*genetics/*metabolism | 3 | 100.0 |
Protein Subunits | 2 | 0.0 |
RNA, Messenger/biosynthesis/genetics | 5 | 0.0 |
Tumor Cells, Cultured/transplantation | 2 | 6.0 |
Guanine Nucleotide Exchange Factors/*physiology | 4 | 44.0 |
Transcription Factor AP-1/metabolism | 4 | 1.0 |
Mitosis/*physiology | 3 | 3.0 |
Magnetic Resonance Spectroscopy | 6 | 1.0 |
Phosphatidylinositol 4,5-Diphosphate/*metabolism | 4 | 26.0 |
GTP-Binding Proteins/*genetics | 5 | 4.0 |
Multigene Family | 5 | 0.0 |
Proto-Oncogene Proteins c-raf/*metabolism | 2 | 5.0 |
ras Proteins/*physiology | 2 | 7.0 |
U937 Cells | 2 | 0.0 |
Cell Cycle Proteins/genetics/*metabolism | 8 | 5.0 |
Endothelium, Vascular/cytology | 6 | 2.0 |
Surface Plasmon Resonance | 2 | 1.0 |
Umbilical Veins/cytology | 3 | 1.0 |
rho GTP-Binding Proteins/*chemistry | 2 | 66.0 |
Cell Survival/drug effects | 2 | 0.0 |
Nerve Growth Factor/pharmacology | 3 | 9.0 |
Actins/*chemistry/*metabolism | 2 | 50.0 |
Nerve Tissue Proteins/*chemistry/genetics/*metabolism | 2 | 13.0 |
Recombinant Proteins/chemistry/metabolism | 6 | 0.0 |
Spodoptera | 5 | 1.0 |
Wiskott-Aldrich Syndrome/genetics | 2 | 28.0 |
Drosophila | 4 | 1.0 |
*MAP Kinase Kinase 4 | 14 | 27.0 |
MAP Kinase Kinase 7 | 6 | 35.0 |
*Protein-Serine-Threonine Kinases | 6 | 0.0 |
Ultraviolet Rays | 4 | 0.0 |
Cell Cycle | 4 | 0.0 |
Cell Cycle Proteins/genetics/*physiology | 2 | 11.0 |
GTP-Binding Proteins/genetics/*physiology | 2 | 11.0 |
Gene Expression Regulation, Developmental | 6 | 0.0 |
Mitotic Spindle Apparatus/*physiology | 2 | 11.0 |
Protein Kinase C/genetics/metabolism | 2 | 50.0 |
Catalysis | 9 | 1.0 |
Conserved Sequence | 6 | 0.0 |
Exons | 4 | 0.0 |
1-Phosphatidylinositol 3-Kinase/metabolism | 16 | 3.0 |
Neutrophils/cytology/*metabolism | 2 | 16.0 |
Receptors, Formyl Peptide | 3 | 4.0 |
*Antigens, Bacterial | 2 | 3.0 |
Bacterial Adhesion/physiology | 2 | 14.0 |
Microfilaments/*metabolism | 4 | 17.0 |
Botulinum Toxins/pharmacology | 3 | 16.0 |
Epidermal Growth Factor/*metabolism/pharmacology | 2 | 3.0 |
Protein Structure, Tertiary/genetics | 7 | 2.0 |
Proteins/genetics/*metabolism | 13 | 2.0 |
Retroviridae Proteins, Oncogenic/*metabolism | 3 | 10.0 |
Signal Transduction/drug effects/*physiology | 5 | 2.0 |
src Homology Domains/genetics | 5 | 8.0 |
DNA-Binding Proteins/metabolism | 7 | 0.0 |
Nuclear Proteins/metabolism | 4 | 0.0 |
Serum Response Factor | 3 | 2.0 |
Leukocytes/metabolism | 2 | 1.0 |
Protein Isoprenylation | 2 | 2.0 |
Cytoskeleton/drug effects/ultrastructure | 2 | 28.0 |
GTP-Binding Proteins/metabolism | 19 | 7.0 |
Thrombin/pharmacology | 7 | 3.0 |
NF-kappa B/*physiology | 2 | 2.0 |
Signal Transduction/physiology | 20 | 2.0 |
Prognosis | 3 | 0.0 |
Quality of Life | 2 | 1.0 |
Prospective Studies | 2 | 0.0 |
Chronic Disease | 2 | 0.0 |
*Gene Expression Profiling | 2 | 0.0 |
Oligonucleotide Array Sequence Analysis | 8 | 0.0 |
Virus Replication | 3 | 0.0 |
Protein-Tyrosine Kinase/*chemistry/metabolism | 2 | 16.0 |
Binding Sites/genetics | 3 | 0.0 |
Mutation/genetics | 11 | 1.0 |
Cell Adhesion/physiology | 9 | 3.0 |
Cell Division/physiology | 4 | 0.0 |
Fibroblasts/cytology/physiology | 2 | 2.0 |
Gene Expression Regulation/physiology | 4 | 1.0 |
Anti-Inflammatory Agents, Non-Steroidal/pharmacology | 2 | 2.0 |
Guanine Nucleotide Dissociation Inhibitors/metabolism | 3 | 37.0 |
Luminescent Proteins/genetics | 4 | 2.0 |
Bacterial Toxins/metabolism | 3 | 33.0 |
Bradykinin/pharmacology | 2 | 4.0 |
Endothelium, Vascular/cytology/drug effects/*metabolism | 2 | 2.0 |
*Lysophospholipids | 3 | 8.0 |
Stress Fibers/drug effects/metabolism | 2 | 33.0 |
DNA/metabolism | 5 | 0.0 |
DNA-Binding Proteins/genetics/*metabolism | 3 | 0.0 |
*Nuclear Proteins | 7 | 0.0 |
Transcription Factors/genetics/*metabolism | 2 | 0.0 |
DNA Primers/genetics | 2 | 0.0 |
Mutagenesis, Insertional | 2 | 0.0 |
Reactive Oxygen Species/metabolism | 3 | 0.0 |
Fibroblasts/cytology/metabolism | 2 | 1.0 |
Spermatocytes/*metabolism | 2 | 33.0 |
Cell Survival | 5 | 0.0 |
Point Mutation | 8 | 0.0 |
Microscopy, Immunoelectron | 3 | 0.0 |
Adenocarcinoma/*metabolism/pathology | 2 | 1.0 |
*Genes, Tumor Suppressor | 3 | 0.0 |
Transcription Factors/*genetics/metabolism | 3 | 0.0 |
NF-kappa B/*metabolism | 5 | 0.0 |
Cell Cycle Proteins/*metabolism | 35 | 10.0 |
Protein Kinase C/*metabolism | 6 | 2.0 |
Proteins/chemistry/genetics/*physiology | 2 | 15.0 |
Collagen Type XVIII | 2 | 18.0 |
Cytotoxins/pharmacology | 4 | 30.0 |
Endostatins | 2 | 4.0 |
Extracellular Matrix/*physiology | 2 | 4.0 |
rac GTP-Binding Proteins/genetics/metabolism | 4 | 66.0 |
Culture Media, Serum-Free | 4 | 1.0 |
Plasmids/genetics/metabolism | 2 | 10.0 |
Cell Adhesion/drug effects | 5 | 1.0 |
Protein-Serine-Threonine Kinases/antagonists & inhibitors | 2 | 2.0 |
GTPase-Activating Proteins/*chemistry/*metabolism | 2 | 100.0 |
*src Homology Domains | 3 | 1.0 |
DNA, Fungal | 3 | 7.0 |
*Chromosome Mapping | 2 | 0.0 |
*cdc42 GTP-Binding Protein | 2 | 100.0 |
Epithelial Cells/*microbiology | 2 | 13.0 |
Hela Cells/*microbiology | 2 | 66.0 |
Abnormalities, Multiple/*genetics | 2 | 0.0 |
Dendrites/*physiology | 2 | 66.0 |
Membrane Proteins/*physiology | 3 | 2.0 |
Cell Polarity/*physiology | 6 | 24.0 |
rac1 GTP-Binding Protein/genetics/metabolism | 6 | 42.0 |
Cytosol/metabolism | 3 | 0.0 |
RNA, Small Interfering/metabolism | 7 | 3.0 |
GTP Phosphohydrolases/*physiology | 4 | 30.0 |
Chromones/pharmacology | 4 | 1.0 |
Escherichia coli/genetics | 2 | 0.0 |
Microtubules/*metabolism | 3 | 4.0 |
Morpholines/pharmacology | 4 | 1.0 |
Protein Biosynthesis | 2 | 0.0 |
Vero Cells | 2 | 0.0 |
Carrier Proteins/*chemistry/genetics/*metabolism | 2 | 4.0 |
Gene Expression Profiling | 8 | 0.0 |
Proteins/chemistry/genetics/metabolism | 2 | 22.0 |
Calcium Signaling/immunology | 2 | 9.0 |
rho GTP-Binding Proteins/metabolism/*physiology | 2 | 66.0 |
*MAP Kinase Kinase Kinase 1 | 6 | 4.0 |
Proto-Oncogene Proteins c-raf/metabolism | 2 | 2.0 |
Brain Chemistry | 3 | 1.0 |
Carrier Proteins/chemistry/genetics/*metabolism | 6 | 4.0 |
Cell Surface Extensions/metabolism | 2 | 16.0 |
Leucine Zippers | 6 | 3.0 |
Polymers/metabolism | 2 | 4.0 |
Wiskott-Aldrich Syndrome | 4 | 80.0 |
*Tumor Suppressor Proteins | 3 | 0.0 |
Chemokines, CXC/pharmacology | 3 | 4.0 |
Chemotaxis, Leukocyte/*drug effects | 2 | 3.0 |
Actins/genetics/metabolism | 2 | 11.0 |
Escherichia coli | 9 | 1.0 |
Glycosylation | 3 | 0.0 |
Chickens | 3 | 0.0 |
Fibroblasts/*metabolism | 2 | 1.0 |
Isoenzymes/*metabolism | 2 | 0.0 |
Cytochalasin D/pharmacology | 5 | 6.0 |
rho GTP-Binding Proteins/genetics/*metabolism | 4 | 26.0 |
Cell Membrane/*metabolism/ultrastructure | 2 | 7.0 |
Chemotaxis/*drug effects | 2 | 4.0 |
Receptors, Cell Surface/*metabolism | 3 | 0.0 |
*Cell Size | 3 | 27.0 |
Phospholipase C/metabolism | 2 | 0.0 |
Proto-Oncogene Proteins/genetics/*metabolism | 7 | 1.0 |
Receptor Protein-Tyrosine Kinases/*metabolism | 2 | 0.0 |
Integrins/*physiology | 4 | 4.0 |
T-Lymphocytes/*physiology | 2 | 0.0 |
Tyrosine | 2 | 1.0 |
Protein Kinase C/metabolism | 7 | 1.0 |
Pseudopodia/drug effects/*metabolism | 3 | 42.0 |
Epithelial Cells/*cytology/physiology | 2 | 40.0 |
Neovascularization, Pathologic | 2 | 0.0 |
Biopolymers | 6 | 5.0 |
Microfilaments/metabolism | 2 | 5.0 |
Phosphatidylinositol 4,5-Diphosphate/metabolism | 3 | 10.0 |
Protein Folding | 4 | 0.0 |
Thermodynamics | 4 | 1.0 |
GTP-Binding Proteins/*metabolism | 49 | 13.0 |
Sequence Analysis, DNA | 7 | 0.0 |
Cyclic AMP-Dependent Protein Kinases/*physiology | 2 | 10.0 |
Guanosine Triphosphate/*metabolism | 4 | 8.0 |
Receptor, PAR-1 | 3 | 14.0 |
Consensus Sequence | 3 | 0.0 |
DNA-Binding Proteins/*metabolism | 5 | 0.0 |
Transcription Factors/*metabolism | 3 | 0.0 |
Cell Membrane/ultrastructure | 3 | 6.0 |
Guanosine Triphosphate/physiology | 3 | 50.0 |
Microfilaments/metabolism/ultrastructure | 2 | 33.0 |
Platelet-Derived Growth Factor/pharmacology | 2 | 1.0 |
Protein Processing, Post-Translational | 3 | 0.0 |
Rabbits | 14 | 0.0 |
Recombinant Fusion Proteins/physiology | 5 | 1.0 |
cdc42 GTP-Binding Protein/chemistry/genetics/*metabolism | 2 | 100.0 |
Macromolecular Substances | 11 | 0.0 |
Neutrophils/physiology | 2 | 1.0 |
Peptides/metabolism | 2 | 0.0 |
Wiskott-Aldrich Syndrome/metabolism | 2 | 50.0 |
RNA, Messenger/analysis/genetics | 3 | 0.0 |
rho GTP-Binding Proteins/*chemistry/genetics/*metabolism | 2 | 100.0 |
Alternative Splicing | 6 | 0.0 |
Epitopes | 3 | 0.0 |
Carrier Proteins/chemistry/*metabolism | 4 | 4.0 |
Caenorhabditis elegans/metabolism | 3 | 25.0 |
*Caenorhabditis elegans Proteins | 5 | 4.0 |
Cell Membrane Permeability | 3 | 1.0 |
Glucosides/pharmacology | 2 | 22.0 |
N-Formylmethionine Leucyl-Phenylalanine/pharmacology | 5 | 1.0 |
Peptide Fragments/pharmacology | 4 | 1.0 |
1-Phosphatidylinositol 3-Kinase/antagonists & inhibitors | 2 | 2.0 |
Cell Adhesion/*drug effects | 2 | 3.0 |
Fibroblasts/*cytology | 2 | 6.0 |
Focal Adhesions | 2 | 15.0 |
Lipopolysaccharides/pharmacology | 3 | 0.0 |
Amino Acid Sequence/genetics | 3 | 1.0 |
Base Sequence/genetics | 2 | 0.0 |
DNA, Complementary/analysis/genetics | 3 | 3.0 |
Phosphoproteins/genetics/metabolism | 2 | 2.0 |
Wiskott-Aldrich Syndrome/genetics/metabolism | 2 | 100.0 |
Actins/*biosynthesis | 2 | 22.0 |
Chromatography, Affinity | 3 | 0.0 |
Nerve Tissue Proteins/chemistry/genetics/*metabolism | 3 | 7.0 |
Neurons/metabolism | 3 | 0.0 |
Peptide Fragments/chemistry/metabolism | 2 | 1.0 |
Alleles | 6 | 0.0 |
Genes, Fungal | 4 | 2.0 |
Isoenzymes/metabolism | 2 | 0.0 |
Proteins/chemistry/*metabolism | 3 | 3.0 |
Proteins/chemistry/genetics/*metabolism | 3 | 3.0 |
Actins/*metabolism/ultrastructure | 4 | 44.0 |
Cytoskeleton/*metabolism/ultrastructure | 3 | 23.0 |
Embryo | 3 | 0.0 |
Fibroblasts/physiology | 2 | 1.0 |
Cytoskeleton/metabolism/ultrastructure | 3 | 14.0 |
T-Lymphocytes/metabolism | 2 | 0.0 |
Antibodies, Monoclonal/pharmacology | 3 | 0.0 |
Carrier Proteins/*physiology | 2 | 0.0 |
Fibronectins/physiology | 2 | 5.0 |
Cadherins/physiology | 4 | 23.0 |
Neoplasms/*pathology | 2 | 3.0 |
Embryo, Nonmammalian | 2 | 5.0 |
GTPase-Activating Proteins/genetics/*metabolism | 2 | 15.0 |
Subcellular Fractions/metabolism | 5 | 1.0 |
Cytoplasm/metabolism | 2 | 0.0 |
Genetic Vectors | 6 | 0.0 |
Proto-Oncogene Proteins/metabolism/*physiology | 3 | 6.0 |
Receptors, Thrombin/*metabolism | 2 | 33.0 |
ADP Ribose Transferases/*metabolism | 3 | 50.0 |
GTP Phosphohydrolases/chemistry/metabolism | 4 | 36.0 |
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2 | 0.0 |
Molecular Weight | 5 | 0.0 |
Mitogen-Activated Protein Kinase Kinases/*metabolism | 3 | 5.0 |
Peptide Mapping | 3 | 0.0 |
Protein Hybridization | 2 | 3.0 |
Genes, Dominant/genetics | 3 | 2.0 |
MAP Kinase Kinase 6 | 2 | 6.0 |
Mitogen-Activated Protein Kinases/genetics/*metabolism | 4 | 9.0 |
Protein-Tyrosine Kinase/genetics/metabolism | 6 | 8.0 |
Cell Cycle/*physiology | 2 | 0.0 |
*Cell Division | 2 | 1.0 |
*GTP Phosphohydrolases | 2 | 22.0 |
Guanosine 5'-O-(3-Thiotriphosphate)/pharmacology | 4 | 5.0 |
Hydrolysis | 8 | 1.0 |
Bacterial Proteins/metabolism | 3 | 4.0 |
Protein-Serine-Threonine Kinases/*chemistry/*metabolism | 2 | 8.0 |
cdc42 GTP-Binding Protein/*chemistry/*metabolism | 2 | 100.0 |
Cytoskeleton/drug effects/physiology | 2 | 40.0 |
Lysophospholipids/pharmacology | 3 | 7.0 |
Phosphatidylinositols/metabolism | 2 | 1.0 |
Protein-Serine-Threonine Kinases/chemistry/*metabolism | 4 | 11.0 |
English Abstract | 2 | 0.0 |
Membrane Fusion/drug effects | 2 | 6.0 |
Receptor, Epidermal Growth Factor/metabolism | 3 | 0.0 |
Enzyme Activation/genetics | 2 | 2.0 |
rho GTP-Binding Proteins/chemistry/*metabolism | 3 | 60.0 |
Imidazoles/pharmacology | 4 | 1.0 |
MAP Kinase Signaling System | 7 | 2.0 |
Chromosomes/genetics | 2 | 2.0 |
DNA, Complementary/chemistry/genetics/*isolation & purification | 2 | 28.0 |
Proteins/*genetics | 4 | 0.0 |
ras GTPase-Activating Proteins/chemistry/*metabolism | 2 | 100.0 |
*Wiskott-Aldrich Syndrome | 2 | 100.0 |
*GTP-Binding Protein beta Subunits | 3 | 17.0 |
*Heterotrimeric GTP-Binding Proteins | 3 | 25.0 |
*Mitogen-Activated Protein Kinase Kinases | 16 | 16.0 |
Protein Kinases/metabolism | 7 | 1.0 |
Signal Transduction/drug effects | 5 | 0.0 |
Xenopus laevis | 3 | 0.0 |
1-Phosphatidylinositol 3-Kinase/antagonists & inhibitors/physiology | 3 | 23.0 |
Bacterial Adhesion/*physiology | 2 | 9.0 |
Cycloheximide/pharmacology | 2 | 0.0 |
Fungal Proteins/genetics/metabolism | 2 | 2.0 |
*Guanine Nucleotide Exchange Factors | 10 | 11.0 |
Protein Binding/genetics | 4 | 1.0 |
Cell-Free System | 4 | 1.0 |
Plasmids | 2 | 0.0 |
src-Family Kinases/*metabolism | 4 | 2.0 |
Recombinant Proteins/chemistry/genetics/metabolism | 4 | 1.0 |
Guanine Nucleotide Exchange Factors/chemistry/genetics/*metabolism | 3 | 30.0 |
Protein-Tyrosine Kinase/genetics/*metabolism | 4 | 2.0 |
Proto-Oncogene Proteins/chemistry/genetics/*metabolism | 2 | 3.0 |
Guanosine Diphosphate/analogs & derivatives/pharmacology | 2 | 33.0 |
Guanosine Triphosphate/*pharmacology | 2 | 66.0 |
Proteins/pharmacology | 3 | 4.0 |
Solubility | 4 | 0.0 |
GTPase-Activating Proteins/*genetics | 2 | 28.0 |
NIH 3T3 Cells | 12 | 4.0 |
Apoptosis/*genetics | 2 | 0.0 |
Cell Cycle Proteins/genetics/metabolism | 7 | 9.0 |
GTP Phosphohydrolases/physiology | 2 | 16.0 |
Exons/genetics | 2 | 0.0 |
Genotype | 2 | 0.0 |
Androstadienes/pharmacology | 6 | 2.0 |
Cell Division/genetics | 3 | 0.0 |
Cell Transformation, Neoplastic/genetics | 2 | 0.0 |
In Situ Nick-End Labeling | 2 | 0.0 |
Proto-Oncogene Proteins/genetics/metabolism | 4 | 2.0 |
Integrin alpha4beta1 | 2 | 2.0 |
Receptors, Lymphocyte Homing/metabolism | 2 | 5.0 |
Cell Membrane/physiology | 3 | 2.0 |
Cell Size/physiology | 2 | 5.0 |
Gene Expression Regulation, Enzymologic | 3 | 0.0 |
Bacterial Toxins/*toxicity | 2 | 9.0 |
Mitotic Spindle Apparatus/metabolism | 2 | 5.0 |
Phagocytosis/*immunology | 2 | 3.0 |
Enzyme Activation/drug effects/physiology | 2 | 3.0 |
cdc42 GTP-Binding Protein/drug effects/*metabolism | 3 | 100.0 |
Cytoskeleton | 3 | 10.0 |
Guanine Nucleotides/metabolism | 2 | 10.0 |
Actins/*physiology | 4 | 11.0 |
Cell Membrane/physiology/ultrastructure | 2 | 8.0 |
Chemotaxis/*physiology | 3 | 8.0 |
Phosphotyrosine/*metabolism | 2 | 3.0 |
Recombinant Proteins | 4 | 0.0 |
Guanine Nucleotides/*metabolism | 3 | 23.0 |
Protein Isoforms/genetics/metabolism | 2 | 1.0 |
GTPase-Activating Proteins | 17 | 10.0 |
*JNK Mitogen-Activated Protein Kinases | 6 | 6.0 |
cdc42 GTP-Binding Protein, Saccharomyces cerevisiae | 28 | 93.0 |
Cell Cycle Proteins/physiology | 4 | 10.0 |
GTP-Binding Proteins/physiology | 2 | 3.0 |
*Phagocytosis/drug effects | 2 | 11.0 |
cdc42 GTP-Binding Protein | 60 | 68.0 |
rac GTP-Binding Proteins | 53 | 32.0 |
Axons/*physiology | 2 | 4.0 |
Embryo, Nonmammalian/physiology | 2 | 6.0 |
GTP-Binding Proteins/genetics/*metabolism | 13 | 15.0 |
rhoA GTP-Binding Protein | 19 | 24.0 |
Enzyme Activation/immunology | 3 | 2.0 |
Wiskott-Aldrich Syndrome/*metabolism | 4 | 80.0 |
Cell Cycle Proteins/*genetics | 3 | 1.0 |
Syndrome | 3 | 0.0 |
*GTP-Binding Protein alpha Subunits, Gi-Go | 3 | 37.0 |
*Mitogen-Activated Protein Kinases | 28 | 8.0 |
Saccharomyces cerevisiae/enzymology | 2 | 3.0 |
Recombinant Fusion Proteins/biosynthesis/chemistry/metabolism | 2 | 8.0 |
GTP-Binding Proteins/genetics/metabolism | 5 | 17.0 |
GTP-Binding Proteins/*genetics/metabolism | 3 | 11.0 |
Guanine Nucleotide Exchange Factors | 7 | 7.0 |
Xenopus | 2 | 0.0 |
Loss of Heterozygosity | 3 | 0.0 |
*Up-Regulation | 3 | 1.0 |
Cell Cycle Proteins/*chemistry/metabolism | 3 | 18.0 |
GTP-Binding Proteins/*chemistry/metabolism | 3 | 30.0 |
Guanosine 5'-O-(3-Thiotriphosphate)/metabolism | 10 | 10.0 |
rho GTP-Binding Proteins | 9 | 33.0 |
Guanylyl Imidodiphosphate/chemistry | 2 | 100.0 |
Magnesium/metabolism | 2 | 2.0 |
Spectrometry, Fluorescence/*methods | 2 | 13.0 |
ras Proteins/chemistry | 2 | 100.0 |
Animals, Genetically Modified | 2 | 0.0 |
rap GTP-Binding Proteins | 4 | 5.0 |
T-Lymphocytes/metabolism/*physiology | 2 | 15.0 |
Eukaryotic Cells/*enzymology | 3 | 17.0 |
Recombinant Fusion Proteins/biosynthesis | 2 | 0.0 |
Apoptosis | 5 | 0.0 |
ADP-Ribosylation Factors | 2 | 1.0 |
Anthranilic Acids/metabolism | 2 | 33.0 |
Cell Cycle Proteins/chemistry/*metabolism | 3 | 11.0 |
Energy Transfer | 2 | 3.0 |
GTP-Binding Proteins/chemistry/*metabolism | 4 | 23.0 |
*Guanine Nucleotide Dissociation Inhibitors | 8 | 24.0 |
*GTPase-Activating Proteins | 3 | 4.0 |
rhoB GTP-Binding Protein | 9 | 33.0 |
Ca(2+)-Calmodulin Dependent Protein Kinase/metabolism | 11 | 3.0 |
ras Proteins/metabolism | 5 | 3.0 |
GTP-Binding Proteins/*physiology | 13 | 12.0 |
Antibodies, Monoclonal/metabolism | 2 | 0.0 |
Tetradecanoylphorbol Acetate/pharmacology | 4 | 0.0 |
Open Reading Frames | 4 | 0.0 |
ras GTPase-Activating Proteins | 8 | 7.0 |
ras Guanine Nucleotide Exchange Factors | 5 | 9.0 |
Treatment Outcome | 3 | 0.0 |
Apoptosis/*physiology | 2 | 0.0 |
GTP-Binding Protein alpha Subunits, G12-G13 | 3 | 18.0 |
MAP Kinase Kinase Kinases | 2 | 20.0 |
Membrane Proteins/*metabolism | 2 | 0.0 |
Cytokines/*metabolism | 2 | 0.0 |
Mitogen-Activated Protein Kinase 1 | 4 | 3.0 |
Umbilical Veins | 2 | 0.0 |
Receptors, Antigen, T-Cell/*metabolism | 2 | 1.0 |
GTP Phosphohydrolases/chemistry | 3 | 50.0 |
Gene Expression Regulation/drug effects | 2 | 0.0 |
GTP-Binding Proteins/metabolism/*physiology | 2 | 16.0 |
Isoenzymes/genetics/metabolism | 2 | 1.0 |
Protein Kinases/genetics/metabolism | 2 | 5.0 |
Cell Cycle Proteins/*physiology | 4 | 7.0 |
Chemokines/*pharmacology | 2 | 7.0 |
Membrane Proteins/physiology | 2 | 2.0 |
Monocytes/*physiology | 2 | 1.0 |
Macrophage Colony-Stimulating Factor/pharmacology | 2 | 2.0 |
Cell Membrane/*enzymology | 2 | 7.0 |
Glutathione Transferase/genetics | 2 | 0.0 |
Phagocytes/*enzymology | 2 | 25.0 |
Phosphoproteins/chemistry/genetics/*metabolism | 2 | 4.0 |
Saccharomyces cerevisiae/genetics/metabolism | 2 | 1.0 |
Cell Membrane | 3 | 4.0 |
Phosphotransferases (Alcohol Group Acceptor)/*metabolism | 2 | 2.0 |
Listeria monocytogenes/metabolism | 2 | 50.0 |
Swine | 4 | 0.0 |
ADP Ribose Transferases/pharmacology | 2 | 6.0 |
*Botulinum Toxins | 3 | 6.0 |
Tumor Necrosis Factor-alpha/*pharmacology | 2 | 0.0 |
Cell Cycle Proteins/*antagonists & inhibitors | 2 | 33.0 |
Endothelium, Vascular/drug effects/metabolism | 2 | 3.0 |
GTP-Binding Proteins/*antagonists & inhibitors | 2 | 28.0 |
*Protein-Tyrosine Kinase | 4 | 1.0 |
*Proto-Oncogene Proteins | 2 | 0.0 |
Fetus | 2 | 0.0 |
RNA, Messenger/biosynthesis | 5 | 0.0 |
Recombinant Proteins/biosynthesis/chemistry | 3 | 3.0 |
Stress | 2 | 3.0 |
Mice, Inbred BALB C | 4 | 0.0 |
Pseudopodia | 2 | 28.0 |
Skin/cytology | 2 | 1.0 |
Recombinant Fusion Proteins | 4 | 1.0 |
Cryptosporidium parvum/*pathogenicity | 2 | 66.0 |
Epithelial Cells/metabolism/parasitology | 2 | 100.0 |
rac GTP-Binding Proteins/*antagonists & inhibitors | 2 | 100.0 |
14-3-3 Proteins | 2 | 1.0 |
*MAP Kinase Kinase Kinases | 2 | 15.0 |
*Tyrosine 3-Monooxygenase | 2 | 4.0 |
Fungal Proteins/*metabolism | 2 | 2.0 |
ral GTP-Binding Proteins | 2 | 18.0 |
Enzyme Induction | 2 | 0.0 |
Insects | 3 | 1.0 |
NADPH Oxidase/metabolism | 3 | 6.0 |
Neurons/chemistry/metabolism | 2 | 22.0 |
RNA, Messenger/*metabolism | 2 | 0.0 |
Nuclear Proteins/*metabolism | 2 | 0.0 |
*Phosphoproteins | 3 | 2.0 |
Proteins/physiology | 2 | 1.0 |
Brain/*metabolism | 2 | 0.0 |
Green Fluorescent Proteins/metabolism | 2 | 3.0 |
Proteins/*genetics/metabolism | 3 | 1.0 |
Phosphatidylinositol 4,5-Diphosphate/biosynthesis | 3 | 75.0 |
MAP Kinase Kinase 3 | 2 | 10.0 |
Liver/*metabolism | 2 | 0.0 |
Actins/chemistry/metabolism | 3 | 42.0 |
Adenosine Triphosphate/chemistry | 2 | 8.0 |
Chromatography, Ion Exchange | 2 | 0.0 |
GTP Phosphohydrolases/*genetics | 2 | 5.0 |
Gene Expression Regulation, Developmental/*physiology | 2 | 1.0 |
Genetic Complementation Test | 2 | 0.0 |
RNA, Messenger/analysis | 2 | 0.0 |
Hydrogen Peroxide/pharmacology | 2 | 0.0 |
Caenorhabditis elegans/genetics | 2 | 2.0 |
Gene Expression Regulation, Fungal | 3 | 4.0 |
Genes, Structural, Fungal | 2 | 8.0 |
Restriction Mapping | 3 | 0.0 |
Guanosine Diphosphate/*metabolism | 2 | 15.0 |
Cell Cycle Proteins/*genetics/metabolism | 2 | 3.0 |
Adenosine Diphosphate Ribose/*metabolism | 3 | 20.0 |
Recombinant Proteins/biosynthesis/metabolism | 2 | 1.0 |
Protein Binding/drug effects | 2 | 0.0 |
p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors/metabolism | 2 | 25.0 |
Proto-Oncogene Protein p21(ras)/*metabolism | 2 | 4.0 |
Kidney/cytology/metabolism | 2 | 2.0 |
Saccharomyces cerevisiae/genetics/physiology | 2 | 20.0 |
*Schizosaccharomyces pombe Proteins | 2 | 2.0 |
Actins | 2 | 25.0 |
Microfilaments/ultrastructure | 2 | 13.0 |
Stress, Mechanical | 2 | 0.0 |
Electrophoresis, Agar Gel | 2 | 0.0 |
Sequence Homology, Nucleic Acid | 3 | 0.0 |
Adenosine Triphosphate/metabolism | 3 | 0.0 |
Transformation, Genetic | 4 | 2.0 |
Blood Proteins/metabolism | 3 | 1.0 |
Tyrosine/*metabolism | 2 | 0.0 |
Cell Cycle Proteins/*biosynthesis | 2 | 4.0 |
Fungal Proteins/genetics | 2 | 1.0 |
Brain/enzymology | 2 | 1.0 |
Kidney | 2 | 0.0 |
Adenoviridae/genetics | 4 | 0.0 |
Protein-Tyrosine Kinase/physiology | 3 | 2.0 |
Disease Progression | 2 | 0.0 |
Microfilament Proteins/*physiology | 2 | 33.0 |
cdc42 GTP-Binding Protein/metabolism/*physiology | 3 | 100.0 |
Chromatography, Gel | 2 | 0.0 |
Endothelial Cells/*cytology | 2 | 12.0 |
Cell Polarity/genetics | 2 | 33.0 |
Genes, Lethal | 2 | 2.0 |
Actins/*chemistry/metabolism | 2 | 33.0 |
Laminin/*metabolism | 2 | 5.0 |
Skin/blood supply | 2 | 3.0 |
Proto-Oncogene Proteins/deficiency/genetics/*physiology | 2 | 18.0 |
Cytoskeleton/drug effects/*metabolism | 2 | 10.0 |
Naphthalenes/pharmacology | 2 | 2.0 |
Wound Healing/physiology | 2 | 3.0 |
Coronary Vessels/cytology | 2 | 14.0 |
rhoB GTP-Binding Protein/metabolism | 2 | 33.0 |
Recombinant Proteins/pharmacology | 2 | 0.0 |
Antigens, CD29/metabolism | 2 | 3.0 |
Focal Adhesions/physiology | 3 | 50.0 |
Glutathione Transferase/genetics/metabolism | 2 | 1.0 |
rhoA GTP-Binding Protein/antagonists & inhibitors/*metabolism | 2 | 25.0 |
Complement 5a/metabolism | 2 | 14.0 |
Trans-Activators/*metabolism | 2 | 0.0 |
Tyrosine/chemistry | 3 | 2.0 |
Escherichia coli Proteins/genetics/*metabolism | 2 | 66.0 |
Pseudopodia/metabolism/ultrastructure | 2 | 40.0 |
src-Family Kinases/*physiology | 3 | 7.0 |
Endocytosis/*physiology | 3 | 2.0 |
Proline/chemistry | 3 | 6.0 |
Cyclic AMP/metabolism | 2 | 0.0 |
DNA, Bacterial/genetics | 2 | 2.0 |
cdc42 GTP-Binding Protein/*metabolism/physiology | 2 | 100.0 |
Active Transport, Cell Nucleus/*physiology | 2 | 5.0 |
Phosphoric Monoester Hydrolases/metabolism | 2 | 2.0 |
Chemotaxis | 2 | 1.0 |
Guanine Nucleotide Exchange Factors/genetics/*metabolism | 4 | 16.0 |
Heterotrimeric GTP-Binding Proteins/*metabolism | 2 | 5.0 |
Cell Movement/*drug effects | 2 | 2.0 |
Pertussis Toxin/pharmacology | 3 | 5.0 |
*Down-Regulation | 2 | 0.0 |
cdc42 GTP-Binding Protein/*biosynthesis | 2 | 100.0 |
Hepatocyte Growth Factor/pharmacology | 2 | 3.0 |
Permeability/drug effects | 2 | 8.0 |
Pseudopodia/*ultrastructure | 2 | 50.0 |
cdc42 GTP-Binding Protein/antagonists & inhibitors/*metabolism | 2 | 100.0 |
rac1 GTP-Binding Protein/metabolism/physiology | 2 | 100.0 |
Protein Processing, Post-Translational/drug effects | 2 | 1.0 |
Cell Death | 2 | 0.0 |
Peptide Fragments/genetics/*metabolism | 2 | 7.0 |
DNA-Binding Proteins/genetics/metabolism | 2 | 0.0 |
Enzyme Activation/physiology | 2 | 1.0 |
NADPH Oxidase/*metabolism | 2 | 4.0 |
