MeSH term
Frequency | Condition_Probility | Animals | 25 | 0.0 |
COS Cells | 2 | 0.0 |
Endopeptidases/metabolism | 2 | 1.0 |
Humans | 46 | 0.0 |
Membrane Proteins/metabolism | 2 | 0.0 |
Models, Biological | 2 | 0.0 |
Protein Binding | 5 | 0.0 |
Protein Structure, Tertiary | 8 | 0.0 |
Research Support, Non-U.S. Gov't | 28 | 0.0 |
Time Factors | 6 | 0.0 |
Transfection | 7 | 0.0 |
Alzheimer Disease/metabolism | 2 | 3.0 |
Amyloid beta-Protein/*metabolism | 7 | 7.0 |
Female | 5 | 0.0 |
Immunohistochemistry | 2 | 0.0 |
Male | 6 | 0.0 |
Mice | 14 | 0.0 |
Mice, Inbred C57BL | 3 | 0.0 |
Mice, Transgenic | 5 | 0.0 |
Protein Processing, Post-Translational | 4 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 11 | 0.0 |
Alzheimer Disease/*enzymology/genetics | 2 | 33.0 |
Amino Acid Sequence | 11 | 0.0 |
Amyloid beta-Protein/*biosynthesis | 4 | 33.0 |
Amyloid beta-Protein Precursor/*metabolism | 5 | 7.0 |
Aspartic Endopeptidases/genetics/*metabolism | 4 | 36.0 |
Mice, Knockout | 4 | 0.0 |
Molecular Sequence Data | 17 | 0.0 |
Aspartic Endopeptidases/*metabolism | 8 | 44.0 |
Biopsy | 2 | 0.0 |
Case-Control Studies | 3 | 0.0 |
Immunoblotting | 2 | 0.0 |
Amyloid beta-Protein Precursor/metabolism | 8 | 22.0 |
Cell Line | 10 | 0.0 |
Golgi Apparatus/*metabolism | 3 | 3.0 |
Substrate Specificity | 6 | 0.0 |
Membrane Microdomains/chemistry/*enzymology | 2 | 100.0 |
Microscopy, Fluorescence | 5 | 0.0 |
Peptide Fragments/metabolism | 2 | 0.0 |
Biological Transport | 2 | 0.0 |
Cell Line, Tumor | 3 | 0.0 |
Endopeptidases/*metabolism | 4 | 3.0 |
Mutation | 5 | 0.0 |
Neurons/metabolism | 2 | 0.0 |
Alzheimer Disease/*metabolism | 3 | 1.0 |
Aspartic Endopeptidases/*chemistry | 4 | 57.0 |
Catalytic Domain | 2 | 0.0 |
Green Fluorescent Proteins | 2 | 0.0 |
Luminescent Proteins/metabolism | 2 | 0.0 |
Plasmids/metabolism | 2 | 0.0 |
Recombinant Fusion Proteins/metabolism | 2 | 0.0 |
Aged | 3 | 0.0 |
Amyloid beta-Protein Precursor/genetics/*metabolism | 3 | 10.0 |
Apolipoproteins E/genetics | 3 | 0.0 |
Aspartic Endopeptidases/*genetics | 5 | 29.0 |
Genotype | 4 | 0.0 |
Aspartic Endopeptidases/metabolism | 3 | 23.0 |
Binding Sites | 4 | 0.0 |
Blotting, Western | 4 | 0.0 |
Cell Membrane/enzymology | 3 | 1.0 |
Analysis of Variance | 2 | 0.0 |
Comparative Study | 7 | 0.0 |
Dose-Response Relationship, Drug | 4 | 0.0 |
Neuroblastoma | 3 | 1.0 |
Reverse Transcriptase Polymerase Chain Reaction/methods | 2 | 0.0 |
Base Sequence | 6 | 0.0 |
DNA Primers | 3 | 0.0 |
Membrane Proteins/genetics/*metabolism | 2 | 0.0 |
RNA Interference | 2 | 0.0 |
Aspartic Endopeptidases/*antagonists & inhibitors | 2 | 50.0 |
Mutagenesis, Site-Directed | 5 | 0.0 |
Sequence Homology, Amino Acid | 3 | 0.0 |
Tumor Cells, Cultured | 2 | 0.0 |
Open Reading Frames/genetics | 2 | 1.0 |
Enzyme Activation | 4 | 0.0 |
*Protein Processing, Post-Translational | 2 | 0.0 |
Aspartic Endopeptidases/antagonists & inhibitors/genetics/*metabolism | 2 | 100.0 |
Disease Models, Animal | 3 | 0.0 |
Brain/metabolism | 2 | 0.0 |
Alzheimer Disease/drug therapy | 2 | 13.0 |
Cells, Cultured | 6 | 0.0 |
Inhibitory Concentration 50 | 3 | 1.0 |
Genes, Reporter | 2 | 0.0 |
Rats | 3 | 0.0 |
Kinetics | 3 | 0.0 |
Alzheimer Disease/genetics/metabolism | 2 | 20.0 |
Cloning, Molecular | 3 | 0.0 |
Up-Regulation | 3 | 0.0 |
Age of Onset | 2 | 0.0 |
Alleles | 2 | 0.0 |
Gene Frequency | 2 | 0.0 |
*Polymorphism, Single Nucleotide | 2 | 0.0 |
Exons | 2 | 0.0 |
Models, Chemical | 2 | 0.0 |
Aspartic Endopeptidases/*biosynthesis | 2 | 66.0 |
Cathepsin D/metabolism | 2 | 5.0 |
Hydrogen-Ion Concentration | 2 | 0.0 |
