MeSH term
Frequency | Condition_Probility | Adult | 159 | 0.0 |
Alleles | 53 | 0.0 |
Case-Control Studies | 23 | 0.0 |
China | 8 | 1.0 |
DNA Mutational Analysis | 5 | 0.0 |
Female | 121 | 0.0 |
Gene Frequency | 44 | 0.0 |
Genotype | 135 | 1.0 |
Humans | 319 | 0.0 |
Male | 202 | 0.0 |
Polymorphism, Single Nucleotide | 2 | 0.0 |
Alcohol Dehydrogenase/*genetics | 51 | 57.0 |
Alcohol Drinking/*adverse effects | 12 | 31.0 |
Aldehyde Dehydrogenase/*genetics | 162 | 94.0 |
Middle Aged | 129 | 0.0 |
Polymorphism, Genetic | 33 | 0.0 |
Research Support, Non-U.S. Gov't | 150 | 0.0 |
Risk Factors | 42 | 0.0 |
Uric Acid/blood | 2 | 3.0 |
Alcohol Drinking/*physiopathology | 2 | 66.0 |
Aldehyde Dehydrogenase/*chemistry/*metabolism | 2 | 100.0 |
Amino Acid Sequence | 12 | 0.0 |
Cloning, Molecular | 4 | 0.0 |
Conserved Sequence | 2 | 0.0 |
Isoenzymes/chemistry/metabolism | 2 | 7.0 |
Kinetics | 15 | 0.0 |
Macromolecular Substances | 4 | 0.0 |
Models, Molecular | 3 | 0.0 |
Molecular Sequence Data | 29 | 0.0 |
Protein Conformation | 4 | 0.0 |
Protein Subunits | 2 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 84 | 0.0 |
Sequence Alignment | 2 | 0.0 |
Sequence Homology, Amino Acid | 4 | 0.0 |
Alcohol Drinking/*genetics/*metabolism | 2 | 66.0 |
Asian Continental Ancestry Group/*genetics | 19 | 5.0 |
Body Mass Index | 6 | 0.0 |
Central Nervous System Depressants/*metabolism | 3 | 75.0 |
Cytochrome P-450 CYP2E1/*genetics | 13 | 10.0 |
Ethanol/*metabolism | 18 | 66.0 |
Japan | 58 | 4.0 |
Polymorphism, Genetic/*genetics | 24 | 1.0 |
Aged | 64 | 0.0 |
Chi-Square Distribution | 8 | 1.0 |
Genetic Predisposition to Disease | 15 | 0.0 |
Logistic Models | 11 | 1.0 |
Age Factors | 6 | 0.0 |
Alcohol Drinking | 8 | 6.0 |
Aldehyde Dehydrogenase/genetics | 23 | 79.0 |
Carcinogens/*adverse effects | 2 | 9.0 |
Cohort Studies | 2 | 0.0 |
Comparative Study | 37 | 0.0 |
DNA-Binding Proteins/*genetics | 2 | 0.0 |
Dose-Response Relationship, Drug | 5 | 0.0 |
Genetic Predisposition to Disease/*genetics | 2 | 0.0 |
Glutathione Transferase/genetics | 5 | 1.0 |
Occupational Exposure/*adverse effects | 2 | 2.0 |
Polyvinyl Chloride/*adverse effects | 2 | 66.0 |
Prevalence | 4 | 0.0 |
Smoking | 6 | 1.0 |
Taiwan/epidemiology | 2 | 1.0 |
Vinyl Chloride/*adverse effects | 2 | 40.0 |
Alcoholism/*genetics/metabolism | 2 | 33.0 |
Mutation | 6 | 0.0 |
Aldehyde Dehydrogenase/*antagonists & inhibitors/*genetics/metabolism | 2 | 100.0 |
Confidence Intervals | 2 | 0.0 |
Gene Frequency/genetics | 11 | 2.0 |
Odds Ratio | 11 | 1.0 |
Receptor, Serotonin, 5-HT1B | 2 | 12.0 |
Receptors, Serotonin/*genetics | 2 | 2.0 |
Alcoholism/epidemiology/*genetics | 2 | 20.0 |
Analysis of Variance | 4 | 0.0 |
Breath Tests | 2 | 2.0 |
Central Nervous System Depressants/pharmacology | 2 | 16.0 |
Ethanol/*pharmacology | 7 | 6.0 |
Flushing/epidemiology/genetics | 2 | 100.0 |
Polymorphism, Restriction Fragment Length | 14 | 0.0 |
Child | 2 | 0.0 |
English Abstract | 24 | 0.0 |
Polymerase Chain Reaction | 45 | 0.0 |
Acetaldehyde/metabolism | 4 | 80.0 |
Alcohol Dehydrogenase/genetics | 16 | 69.0 |
Animals | 42 | 0.0 |
Japan/epidemiology | 16 | 4.0 |
*Alleles | 14 | 1.0 |
DNA Primers/chemistry | 2 | 0.0 |
Polymerase Chain Reaction/*methods | 3 | 0.0 |
Polymorphism, Single Nucleotide/*genetics | 4 | 1.0 |
Staining and Labeling | 2 | 0.0 |
Carcinoma, Hepatocellular | 4 | 1.0 |
Enzyme Activation | 2 | 0.0 |
Gene Expression Regulation, Enzymologic/*drug effects | 3 | 2.0 |
Kidney/enzymology | 2 | 1.0 |
Liver/enzymology | 12 | 2.0 |
Rats | 17 | 0.0 |
Transcription, Genetic/drug effects | 2 | 0.0 |
Transfection | 6 | 0.0 |
Tumor Cells, Cultured | 5 | 0.0 |
Asian Continental Ancestry Group/genetics | 11 | 3.0 |
Base Sequence | 28 | 0.0 |
DNA Primers/genetics | 3 | 0.0 |
China/ethnology | 11 | 5.0 |
Korea/ethnology | 6 | 33.0 |
Alcoholism/enzymology/genetics | 4 | 66.0 |
Central Nervous System Depressants/pharmacokinetics | 2 | 100.0 |
Ethanol/pharmacokinetics | 10 | 50.0 |
Korea | 2 | 0.0 |
Liver Cirrhosis, Alcoholic/enzymology/*genetics | 4 | 80.0 |
*Polymorphism, Genetic | 45 | 0.0 |
Asian Americans | 2 | 13.0 |
Double-Blind Method | 4 | 0.0 |
Heart Rate/drug effects | 3 | 1.0 |
Placebos | 2 | 0.0 |
Questionnaires | 13 | 2.0 |
Sex Characteristics | 3 | 0.0 |
Polymerase Chain Reaction/methods | 4 | 0.0 |
Genetics, Population | 11 | 2.0 |
Receptors, Dopamine D2/*genetics | 5 | 1.0 |
DNA Restriction Enzymes | 4 | 1.0 |
*Genotype | 33 | 15.0 |
Hypersensitivity | 2 | 16.0 |
Isoenzymes/*genetics | 38 | 8.0 |
Alcohol Drinking/epidemiology/genetics | 2 | 100.0 |
California | 2 | 4.0 |
*Phenotype | 4 | 1.0 |
Risk | 6 | 0.0 |
Acetaldehyde/blood | 6 | 85.0 |
Alcohol Drinking/blood/*genetics | 3 | 100.0 |
Aldehyde Dehydrogenase/*genetics/*metabolism | 3 | 75.0 |
Asia/ethnology | 2 | 6.0 |
Liver Neoplasms, Experimental | 2 | 4.0 |
Mitochondria, Liver/*enzymology | 10 | 37.0 |
Phenotype | 15 | 0.0 |
Rats, Sprague-Dawley | 4 | 0.0 |
Recombinant Proteins/metabolism | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 2 | 0.0 |
Data Collection | 2 | 2.0 |
Genetic Screening | 2 | 0.0 |
Linkage Disequilibrium | 5 | 0.0 |
Pregnancy | 2 | 0.0 |
Regression Analysis | 7 | 0.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 11 | 0.0 |
Aldehyde Oxidoreductases/*genetics | 6 | 35.0 |
Follow-Up Studies | 3 | 0.0 |
Health Promotion | 2 | 25.0 |
Smoking/*adverse effects | 5 | 2.0 |
Taiwan | 10 | 5.0 |
Time Factors | 4 | 0.0 |
Blood Pressure/*drug effects | 3 | 1.0 |
Aldehyde Dehydrogenase/genetics/*metabolism | 5 | 71.0 |
Blotting, Northern | 3 | 0.0 |
Blotting, Western | 2 | 0.0 |
Mice | 10 | 0.0 |
Mice, Knockout | 2 | 0.0 |
Mitochondria/*enzymology | 13 | 11.0 |
*Promoter Regions (Genetics) | 3 | 0.0 |
Asia/epidemiology | 2 | 12.0 |
*Genetic Predisposition to Disease | 8 | 0.0 |
*Genetics, Population | 5 | 1.0 |
Incidence | 2 | 0.0 |
Cytosol/enzymology | 6 | 3.0 |
Enzyme Stability | 2 | 1.0 |
Mitochondria/enzymology | 7 | 6.0 |
Protein Denaturation | 2 | 0.0 |
Ethanol/administration & dosage | 4 | 36.0 |
Exons | 5 | 0.0 |
*Polymorphism, Restriction Fragment Length | 8 | 1.0 |
Polymorphism, Single-Stranded Conformational | 6 | 0.0 |
Promoter Regions (Genetics) | 5 | 0.0 |
Sequence Analysis, DNA | 2 | 0.0 |
Alanine Transaminase/blood | 4 | 2.0 |
Alcohol Drinking/*genetics | 9 | 52.0 |
Aspartate Aminotransferases/blood | 4 | 3.0 |
Heterozygote | 11 | 0.0 |
Homozygote | 14 | 0.0 |
Liver Diseases, Alcoholic/*genetics | 4 | 50.0 |
gamma-Glutamyltransferase/blood | 4 | 8.0 |
Blood Pressure/drug effects | 2 | 0.0 |
Skin Temperature/drug effects | 2 | 40.0 |
Biological Markers/analysis | 3 | 0.0 |
Life Style | 2 | 1.0 |
Reference Values | 11 | 0.0 |
Alcoholism/genetics | 7 | 29.0 |
Alcoholism/*genetics | 14 | 15.0 |
Mexican Americans/*genetics | 2 | 8.0 |
*Genetic Techniques | 2 | 3.0 |
Adolescent | 13 | 0.0 |
Aged, 80 and over | 11 | 0.0 |
Acetaldehyde/*metabolism | 2 | 40.0 |
Alcohol Drinking/*genetics/metabolism | 3 | 75.0 |
Alcohol-Related Disorders/*genetics/metabolism | 2 | 100.0 |
Aldehyde Dehydrogenase/*genetics/metabolism | 12 | 92.0 |
Cytochrome P-450 CYP2E1/*genetics/metabolism | 2 | 9.0 |
Japan/ethnology | 9 | 12.0 |
Polymorphism, Genetic/genetics | 6 | 0.0 |
Chromatography, Affinity | 3 | 0.0 |
Hydrogen-Ion Concentration | 2 | 0.0 |
In Vitro | 2 | 0.0 |
Molecular Weight | 2 | 0.0 |
Species Specificity | 5 | 0.0 |
Binding Sites | 3 | 0.0 |
Crystallography, X-Ray | 2 | 0.0 |
Mutagenesis, Site-Directed | 3 | 0.0 |
Alcohol Drinking/ethnology/*genetics | 3 | 100.0 |
DNA Primers | 10 | 0.0 |
Alcohol Drinking/*epidemiology | 3 | 50.0 |
Smoking/*epidemiology | 2 | 20.0 |
Alcohol Dehydrogenase/*genetics/metabolism | 7 | 70.0 |
Chromosome Mapping | 10 | 0.0 |
Crosses, Genetic | 2 | 0.0 |
Mice, Inbred C57BL | 3 | 0.0 |
RNA, Messenger/metabolism | 3 | 0.0 |
Linkage Disequilibrium/*genetics | 2 | 2.0 |
Interleukin-1/genetics | 2 | 2.0 |
NAD(P)H Dehydrogenase (Quinone)/genetics | 2 | 11.0 |
Peptidyl-Dipeptidase A/genetics | 2 | 2.0 |
Physical Examination | 2 | 7.0 |
Quinone Reductases/genetics | 2 | 28.0 |
Tumor Necrosis Factor-alpha/genetics | 2 | 0.0 |
Mass Screening | 2 | 1.0 |
Cytochrome P-450 CYP2E1/genetics | 7 | 18.0 |
Ethnic Groups/*genetics | 7 | 3.0 |
Isoenzymes/genetics | 7 | 2.0 |
Flushing/chemically induced/enzymology/genetics | 2 | 100.0 |
Mitochondria, Liver/enzymology | 6 | 24.0 |
Alcohol Drinking/epidemiology/*genetics/metabolism | 2 | 66.0 |
Linear Models | 2 | 0.0 |
Liver Function Tests | 4 | 2.0 |
Cause of Death | 2 | 1.0 |
Mass Fragmentography | 2 | 0.0 |
Liver/enzymology/*metabolism | 2 | 5.0 |
Oxidation-Reduction | 2 | 0.0 |
Neoplasm Proteins/*genetics | 2 | 0.0 |
Chromosomes, Human, Pair 12/genetics | 2 | 2.0 |
Aldehyde Dehydrogenase/*deficiency/genetics | 3 | 100.0 |
Apolipoproteins E/genetics | 3 | 0.0 |
Genes, Dominant/genetics | 2 | 1.0 |
Acetaldehyde/*blood | 6 | 100.0 |
Alcohol Drinking/genetics | 4 | 40.0 |
Ethanol/blood | 2 | 22.0 |
Nutritional Status | 2 | 1.0 |
Alcohol Dehydrogenase/biosynthesis/*genetics | 2 | 66.0 |
Aldehyde Dehydrogenase/biosynthesis/*genetics | 3 | 60.0 |
*Polymorphism, Single Nucleotide | 4 | 0.0 |
Alcoholism/enzymology/*genetics | 8 | 80.0 |
Ethanol/administration & dosage/blood | 2 | 100.0 |
Asian Americans/*genetics/psychology | 2 | 100.0 |
Multivariate Analysis | 5 | 0.0 |
Reproducibility of Results | 3 | 0.0 |
Sex Factors | 5 | 0.0 |
Cytochrome P-450 CYP1A1/genetics | 2 | 2.0 |
Chromosomes, Human, Pair 12 | 2 | 1.0 |
Haplotypes | 6 | 0.0 |
Models, Genetic | 5 | 0.0 |
Variation (Genetics) | 4 | 0.0 |
Point Mutation | 5 | 0.0 |
Sister Chromatid Exchange | 3 | 6.0 |
Age Distribution | 2 | 0.0 |
Ethanol/pharmacology | 2 | 3.0 |
European Continental Ancestry Group/genetics | 7 | 1.0 |
Thailand | 2 | 1.0 |
Aldehyde Dehydrogenase/blood/*genetics | 4 | 100.0 |
Flushing/*etiology | 3 | 60.0 |
African Continental Ancestry Group/genetics | 2 | 0.0 |
Gene Deletion | 2 | 0.0 |
Aldehyde Dehydrogenase/analysis/*genetics | 2 | 100.0 |
Disulfiram/pharmacology | 2 | 22.0 |
Enzyme Inhibitors/pharmacology | 3 | 0.0 |
RNA, Messenger/analysis | 2 | 0.0 |
Rats, Wistar | 2 | 0.0 |
Esophageal Neoplasms/chemically induced/*enzymology/genetics | 2 | 100.0 |
Ethanol/*adverse effects | 2 | 8.0 |
*Variation (Genetics) | 6 | 0.0 |
Aldehyde Dehydrogenase/deficiency/*genetics | 8 | 100.0 |
Hypertension/epidemiology/*genetics | 2 | 10.0 |
Cytochrome P-450 Enzyme System/genetics/metabolism | 2 | 4.0 |
DNA Damage | 2 | 0.0 |
Glutathione Transferase/genetics/metabolism | 2 | 1.0 |
*Occupational Exposure | 3 | 2.0 |
Cell Transformation, Neoplastic | 2 | 0.0 |
Cross-Sectional Studies | 5 | 0.0 |
Immunohistochemistry | 2 | 0.0 |
Alcohol Drinking/*adverse effects/genetics | 2 | 100.0 |
Flushing/*genetics | 4 | 100.0 |
Renal Dialysis | 2 | 0.0 |
Stomach Neoplasms/enzymology/genetics | 2 | 28.0 |
Alcohol Drinking/adverse effects/*genetics | 3 | 60.0 |
Gene Expression Regulation, Enzymologic/physiology | 7 | 8.0 |
Ethanol/*pharmacokinetics | 9 | 60.0 |
Flushing/genetics | 6 | 85.0 |
Hela Cells | 4 | 0.0 |
Genetic Markers | 3 | 0.0 |
DNA/analysis | 3 | 0.0 |
*Chromosome Mapping | 4 | 0.0 |
*Chromosomes, Human, Pair 12 | 2 | 0.0 |
Pedigree | 3 | 0.0 |
Asia | 3 | 4.0 |
Asian Continental Ancestry Group | 9 | 3.0 |
Enzyme Inhibitors/*pharmacology | 2 | 0.0 |
Aldehyde Oxidoreductases/*genetics/metabolism | 2 | 66.0 |
Disease Susceptibility | 3 | 0.0 |
Aldehyde Dehydrogenase/*deficiency/*genetics | 2 | 100.0 |
*Oxidative Stress | 2 | 0.0 |
PC12 Cells | 2 | 0.0 |
Workplace | 2 | 40.0 |
Aldehyde Dehydrogenase/chemistry/*genetics | 2 | 100.0 |
*Evolution, Molecular | 2 | 0.0 |
*Mutation | 2 | 0.0 |
*Phylogeny | 2 | 1.0 |
Disease Progression | 2 | 0.0 |
Genetic Predisposition to Disease/genetics | 3 | 0.0 |
United States | 3 | 0.0 |
Glutathione Transferase/*genetics | 2 | 0.0 |
Electrophoresis, Polyacrylamide Gel | 3 | 0.0 |
Biological Markers | 2 | 0.0 |
*Alcohol Drinking | 3 | 12.0 |
Flushing/*chemically induced | 3 | 100.0 |
Smoking/adverse effects | 2 | 0.0 |
*Membrane Transport Proteins | 2 | 0.0 |
Asian Americans/*genetics | 3 | 33.0 |
Ethanol/*blood | 3 | 75.0 |
Structure-Activity Relationship | 2 | 0.0 |
Alcohol Dehydrogenase/genetics/*metabolism | 2 | 66.0 |
Ethanol/metabolism | 8 | 36.0 |
Alcoholism/*genetics/psychology | 2 | 20.0 |
Liver Diseases, Alcoholic/enzymology/*genetics | 5 | 71.0 |
Cattle | 3 | 0.0 |
Alcohol Drinking/*metabolism | 2 | 22.0 |
DNA, Mitochondrial/genetics | 2 | 4.0 |
Mutation/genetics | 3 | 0.0 |
Occupational Exposure | 2 | 2.0 |
Aldehyde Dehydrogenase/metabolism | 3 | 37.0 |
*Flushing | 2 | 100.0 |
Patch Tests | 2 | 6.0 |
Alcoholism/*complications | 3 | 15.0 |
*Asian Continental Ancestry Group | 3 | 4.0 |
Glutamic Acid | 2 | 2.0 |
Isoelectric Focusing | 13 | 2.0 |
Alcohol Drinking/*blood | 3 | 21.0 |
Aldehyde Dehydrogenase/*genetics/physiology | 3 | 75.0 |
Chronic Disease | 2 | 0.0 |
Isoenzymes/*genetics/physiology | 2 | 20.0 |
Acetaldehyde/*pharmacokinetics | 3 | 100.0 |
*Point Mutation | 2 | 0.0 |
Ethanol | 2 | 9.0 |
Genes, Dominant | 3 | 0.0 |
*Gene Expression Regulation, Enzymologic | 3 | 0.0 |
Transcription, Genetic | 3 | 0.0 |
Deoxyribonucleases, Type II Site-Specific | 3 | 1.0 |
Restriction Mapping | 2 | 0.0 |
Carcinoma, Squamous Cell/*etiology/pathology | 2 | 50.0 |
Esophageal Neoplasms/*etiology/pathology | 2 | 66.0 |
Cells, Cultured | 5 | 0.0 |
Aldehyde Dehydrogenase/*metabolism | 4 | 44.0 |
Isoenzymes/*metabolism | 2 | 0.0 |
Alcoholism/enzymology/ethnology/*genetics | 3 | 100.0 |
*Ethnic Groups | 2 | 1.0 |
Alcohol Drinking/adverse effects | 5 | 10.0 |
Tissue Distribution | 2 | 0.0 |
Cytochrome P-450 CYP2E1 | 9 | 8.0 |
Cytochrome P-450 Enzyme System/*genetics | 10 | 2.0 |
Oxidoreductases, N-Demethylating/*genetics | 7 | 16.0 |
Aldehyde Dehydrogenase/genetics/metabolism | 2 | 50.0 |
Cytochrome P-450 CYP1A1 | 2 | 4.0 |
Hippurates/*urine | 2 | 66.0 |
Cell Line | 4 | 0.0 |
Liver Neoplasms | 3 | 1.0 |
Alcohol Drinking/*adverse effects/ethnology | 2 | 66.0 |
DNA/genetics | 5 | 0.0 |
Indians, North American/*genetics | 3 | 3.0 |
Isoenzymes/deficiency/*genetics | 3 | 50.0 |
Hippurates/urine | 3 | 75.0 |
Alcoholism/ethnology/*genetics | 3 | 33.0 |
Isoenzymes/*genetics/metabolism | 2 | 3.0 |
Indians, South American/*genetics | 2 | 3.0 |
Hair/enzymology | 4 | 80.0 |
*Indians, South American | 2 | 8.0 |
*Heterozygote Detection | 2 | 1.0 |
Mexico | 2 | 2.0 |
Toluene/*metabolism | 3 | 37.0 |
Cytochrome P-450 Enzyme System/genetics | 2 | 1.0 |
Linkage (Genetics) | 2 | 0.0 |
Oxidoreductases, N-Demethylating/genetics | 2 | 18.0 |
Heterozygote Detection | 3 | 0.0 |
*Environmental Monitoring | 2 | 6.0 |
European Continental Ancestry Group/*genetics | 2 | 0.0 |
Flushing/enzymology/*genetics | 2 | 100.0 |
Alcoholism/*enzymology/genetics | 3 | 50.0 |
European Continental Ancestry Group | 5 | 0.0 |
Hamsters | 3 | 0.0 |
Hybrid Cells | 3 | 0.0 |
Oligonucleotide Probes | 2 | 0.0 |
Alcohol Drinking/physiopathology | 2 | 50.0 |
Nucleic Acid Hybridization | 7 | 0.0 |
Lipoproteins, HDL Cholesterol/*blood | 2 | 0.0 |
Erythrocytes/enzymology | 2 | 0.0 |
Liver/*enzymology | 8 | 1.0 |
*Cross-Cultural Comparison | 2 | 14.0 |
Aldehyde Dehydrogenase/*genetics/pharmacology | 2 | 100.0 |
DNA Probes | 5 | 0.0 |
Chile | 2 | 3.0 |
Electrophoresis, Starch Gel | 6 | 4.0 |
Immunoblotting | 2 | 0.0 |
Aldehyde Dehydrogenase/*blood | 2 | 100.0 |
Electrophoresis, Agar Gel | 2 | 0.0 |
*Genes, Structural | 2 | 0.0 |
Hepatitis C/*complications | 2 | 11.0 |
Liver Neoplasms/*etiology | 2 | 16.0 |
Universities/statistics & numerical data | 2 | 33.0 |
Immunoassay/*methods | 2 | 2.0 |
Aldehyde Dehydrogenase/*genetics/immunology | 2 | 100.0 |
Immunoelectrophoresis, Two-Dimensional | 3 | 2.0 |
DNA/*analysis | 2 | 0.0 |
Aldehyde Dehydrogenase | 4 | 100.0 |
Amino Acids/analysis | 2 | 0.0 |
Alcohol Drinking/epidemiology/*genetics | 2 | 50.0 |
Blood Pressure/*genetics | 2 | 3.0 |
Genetic Predisposition to Disease/epidemiology | 2 | 2.0 |
