MeSH term
Frequency | Condition_Probility | Adult | 11 | 0.0 |
Humans | 67 | 0.0 |
Male | 16 | 0.0 |
Middle Aged | 6 | 0.0 |
Weight Loss | 3 | 2.0 |
Animals | 49 | 0.0 |
Amino Acid Substitution | 2 | 0.0 |
Cell Line | 15 | 0.0 |
Mice | 20 | 0.0 |
Oligopeptides/*chemical synthesis/chemistry/pharmacology | 2 | 50.0 |
Receptor, Melanocortin, Type 3 | 7 | 25.0 |
Receptor, Melanocortin, Type 4 | 17 | 25.0 |
Receptors, Melanocortin | 12 | 12.0 |
Research Support, Non-U.S. Gov't | 41 | 0.0 |
Research Support, U.S. Gov't, P.H.S. | 31 | 0.0 |
Structure-Activity Relationship | 6 | 0.0 |
Amino Acid Sequence | 19 | 0.0 |
Binding, Competitive | 4 | 0.0 |
Molecular Sequence Data | 19 | 0.0 |
Protein Folding | 4 | 0.0 |
Protein Structure, Tertiary | 4 | 0.0 |
Base Sequence | 3 | 0.0 |
Sequence Homology, Amino Acid | 4 | 0.0 |
Species Specificity | 2 | 0.0 |
Swine/*genetics | 2 | 1.0 |
Anti-Obesity Agents/chemistry/therapeutic use | 2 | 100.0 |
Body Weight/drug effects/*physiology | 2 | 100.0 |
Gene Expression | 2 | 0.0 |
MSH/genetics/*physiology | 3 | 100.0 |
Obesity/drug therapy/*physiopathology | 2 | 100.0 |
Receptors, Corticotropin/drug effects/genetics/physiology | 2 | 100.0 |
Fluorescent Antibody Technique, Indirect | 2 | 0.0 |
Immunohistochemistry | 2 | 0.0 |
Neurons/*metabolism | 2 | 0.0 |
Proteins/metabolism | 3 | 0.0 |
Body Weight/*physiology | 3 | 9.0 |
Proteins/physiology | 4 | 2.0 |
Signal Transduction | 2 | 0.0 |
Aged | 2 | 0.0 |
Aged, 80 and over | 2 | 0.0 |
Female | 13 | 0.0 |
Hypothalamus/*metabolism | 2 | 6.0 |
Proteins/genetics/*metabolism | 2 | 0.0 |
RNA, Messenger/metabolism | 3 | 0.0 |
Tissue Distribution | 2 | 0.0 |
Amino Acid Motifs | 2 | 0.0 |
Models, Molecular | 9 | 0.0 |
Protein Structure, Secondary | 4 | 0.0 |
*Intercellular Signaling Peptides and Proteins | 6 | 1.0 |
Magnetic Resonance Spectroscopy | 3 | 0.0 |
Peptides, Cyclic/*chemical synthesis/chemistry/pharmacology | 3 | 50.0 |
Proteins/*chemistry | 4 | 4.0 |
*Receptor, Melanocortin, Type 3 | 4 | 57.0 |
Research Support, U.S. Gov't, Non-P.H.S. | 5 | 0.0 |
Transfection | 7 | 0.0 |
DNA Primers | 2 | 0.0 |
Gene Frequency | 3 | 0.0 |
Polymerase Chain Reaction | 2 | 0.0 |
Polymorphism, Genetic | 2 | 0.0 |
Polymorphism, Restriction Fragment Length | 2 | 0.0 |
Proteins/*genetics | 7 | 0.0 |
Mice, Transgenic | 2 | 0.0 |
Adolescent | 3 | 0.0 |
Body Mass Index | 2 | 0.0 |
Case-Control Studies | 2 | 0.0 |
Child | 2 | 0.0 |
Obesity/*genetics | 3 | 2.0 |
Pedigree | 2 | 0.0 |
Injections, Intraventricular | 3 | 2.0 |
Peptide Fragments/*pharmacology | 4 | 2.0 |
Leptin/blood | 2 | 3.0 |
Proteins/*analysis | 3 | 2.0 |
Fasting | 2 | 0.0 |
Genetic Screening | 2 | 0.0 |
Mutation, Missense | 3 | 0.0 |
Proteins/*pharmacology | 3 | 4.0 |
alpha-MSH/pharmacology | 2 | 16.0 |
Eating | 2 | 1.0 |
Frameshift Mutation | 2 | 0.0 |
Heterozygote | 2 | 0.0 |
*Mutation | 2 | 0.0 |
alpha-MSH/metabolism | 5 | 33.0 |
Proteins/*physiology | 2 | 1.0 |
Hypothalamus/*physiology | 2 | 7.0 |
Leptin/*physiology | 3 | 27.0 |
Rats | 7 | 0.0 |
Recombinant Proteins/chemistry | 2 | 0.0 |
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2 | 0.0 |
Leptin/*blood | 2 | 2.0 |
Hypothalamus/metabolism | 2 | 4.0 |
Receptors, Peptide/genetics/metabolism | 2 | 16.0 |
Eating/*physiology | 3 | 4.0 |
Energy Metabolism/*physiology | 4 | 4.0 |
MSH/metabolism | 2 | 33.0 |
Protein Binding | 5 | 0.0 |
Protein Conformation | 4 | 0.0 |
Proteins/*metabolism | 2 | 0.0 |
Peptides, Cyclic/pharmacology | 2 | 5.0 |
Sequence Alignment | 4 | 0.0 |
Cyclic AMP/metabolism | 6 | 1.0 |
Iodine Radioisotopes | 2 | 0.0 |
Receptors, Corticotropin/genetics/*metabolism | 2 | 20.0 |
Oxidation-Reduction | 2 | 0.0 |
Dose-Response Relationship, Drug | 3 | 0.0 |
Rats, Wistar | 3 | 0.0 |
Comparative Study | 3 | 0.0 |
Peptide Fragments/pharmacology | 2 | 0.0 |
Cyclic AMP/biosynthesis | 3 | 2.0 |
*Polymorphism, Single Nucleotide | 3 | 0.0 |
Trans-Activation (Genetics) | 2 | 0.0 |
Drug Design | 3 | 0.0 |
Ligands | 3 | 0.0 |
Radioligand Assay | 3 | 0.0 |
Cells, Cultured | 2 | 0.0 |
Body Weight | 2 | 0.0 |
Genotype | 3 | 0.0 |
Proteins/*genetics/metabolism | 2 | 0.0 |
Reverse Transcriptase Polymerase Chain Reaction | 3 | 0.0 |
alpha-MSH/physiology | 2 | 33.0 |
Kinetics | 2 | 0.0 |
Peptide Hormones/physiology | 2 | 100.0 |
Eating/physiology | 2 | 3.0 |
Receptors, Corticotropin/physiology | 2 | 25.0 |
Time Factors | 2 | 0.0 |